[CAS NO. 1190836-34-0]  Pamufetinib (TAS-115)

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PRODUCTS SPECIFICATIONS [1190836-34-0]

Catalog
SLK-S6764
Brand
Selleck
CAS
1190836-34-0

DESCRIPTION [1190836-34-0]

Overview

MDL-
Molecular Weight518.56
Molecular FormulaC27H23FN4O4S
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.9284 mL9.6421 mL19.2842 mL
5 mM0.3857 mL1.9284 mL3.8568 mL
10 mM0.1928 mL0.9642 mL1.9284 mL
50 mM---

Description

Pamufetinib (TAS-115) is a highly potent and dual inhibitor with IC50s of 30 nM and 32 nM for recombinant VEGFR2 and recombinant MET, respectively.

Targets

recombinant VEGFR2 [1]
(Cell-free assay)
recombinant VEGFR2 [1]
(Cell-free assay)
recombinant MET [1]
(Cell-free assay)
recombinant MET [1]
(Cell-free assay)
30 nM30 nM32 nM32 nM