[CAS NO. 1361951-15-6] TP-3654

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PRODUCTS SPECIFICATIONS [1361951-15-6]

Catalog

SLK-S6774

Brand

Selleck

CAS

1361951-15-6

MDL	MFCD28502206
Molecular Weight	418.46
Molecular Formula	C22H25F3N4O
SMILES	OC(C)([C@H]1CC[C@@H](CC1)NC2=NN3C(C=C2)=NC=C3C4=CC=CC(C(F)(F)F)=C4)C

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

TP-3654 is the second-generation inhibitor with K values of 5 nM, 239 nM, and 42 nM for PIM-1, PIM-2 and PIM-3, respectively.

Pim1 ^[1] (Cell-free assay)	Pim3 ^[1] (Cell-free assay)	Pim2 ^[1] (Cell-free assay)
5 nM(Ki)	42 nM(Ki)	239 nM(Ki)