[CAS NO. 285986-31-4] STAT5-IN-1
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PRODUCTS SPECIFICATIONS [285986-31-4]
Store
Catalog
SLK-S6784
Brand
Selleck
CAS
285986-31-4
DESCRIPTION [285986-31-4]
Overview
| MDL | MFCD00124694 |
|---|---|
| Molecular Weight | 293.28 |
| Molecular Formula | C16H11N3O3 |
| SMILES | O=C1C=2C(OC=C1C=NNC(=O)C=3C=CC=NC3)=CC=CC2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
STAT5-IN-1 is a potent and selective inhibitor with IC50 of 47 μM for STAT5β isoform.
Targets
| STAT5β [1] (Cell-free assay) |
| 47 μM |
In vitro
STAT5-IN-1, the STAT5 phosphorylation specific inhibitor, selectively blocks the STAT5 signaling and decreases the percentage of CD4+CD25+Foxp3+ Tregs after SEC2 stimulation on murine splenocytes.
References
Synonyms
3-Pyridinecarboxylic acid, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide
3-Pyridinecarboxylic acid, [(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide
3-Pyridinecarboxylic acid 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide
SC 355979
STAT 5-IN-1
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