[CAS NO. 1798331-92-6]  QX77

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PRODUCTS SPECIFICATIONS [1798331-92-6]

Catalog
SLK-S6797
Brand
Selleck
CAS
1798331-92-6

DESCRIPTION [1798331-92-6]

Overview

MDL-
Molecular Weight300.74
Molecular FormulaC16H13ClN2O2
SMILESCC(NC1=CC=C(C2=NC3=CC=C(Cl)C=C3OC2)C=C1)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.3251 mL16.6257 mL33.2513 mL
5 mM0.6650 mL3.3251 mL6.6503 mL
10 mM0.3325 mL1.6626 mL3.3251 mL
50 mM0.0665 mL0.3325 mL0.6650 mL

Description

QX77 is a novel activator of . QX77 induces the up-regulation of Rab11 expression and up-regulates LAMP2A expression.

Targets

CMA [1]

In vitro

QX77, an activator of CMA, eliminates the effects of milk fat globule-EGF factor 8 (MFG-E8) on TGF-β1-induced human pancreatic stellate cells (PSCs) activation. QX77 mitigates the suppressive effect of MFG-E8 on oxidative stress in activated PSCs.