[CAS NO. 1313881-70-7]  Miransertib (ARQ-092)

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PRODUCTS SPECIFICATIONS [1313881-70-7]

Store
Catalog
SLK-S6811
Brand
Selleck
CAS
1313881-70-7

DESCRIPTION [1313881-70-7]

Overview

MDLMFCD30187510
Molecular Weight432.52
Molecular FormulaC27H24N6
SMILESNC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3120 mL11.5602 mL23.1203 mL
5 mM0.4624 mL2.3120 mL4.6241 mL
10 mM0.2312 mL1.1560 mL2.3120 mL
50 mM---

Description

Miransertib (ARQ-092) is a potent, selective and orally bioavailable allosteric inhibitor of with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.

Targets

Akt1 [1]
(Cell-free assay)
Akt3 [1]
(Cell-free assay)
Akt2 [1]
(Cell-free assay)
2.7 nM8.1 nM14 nM