Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
1.7318 mL
8.6592 mL
17.3184 mL
5 mM
0.3464 mL
1.7318 mL
3.4637 mL
10 mM
0.1732 mL
0.8659 mL
1.7318 mL
50 mM
0.0346 mL
0.1732 mL
0.3464 mL
Description
Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the and prevents the release of lysosomal content without affecting the process of resealing. Vacuolin-1 is also a potent and selective inhibitor, and inhibits by impairing lysosomal maturation via PIKfyve inhibition.
Vacuolin-1 blocks both ionophore- and wound-induced, Ca-dependent exocytosis of lysosomes, but does not block Ca-dependent fusion of enlargeosomes with the plasma membrane.
