[CAS NO. 2061344-88-3] 6H05
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PRODUCTS SPECIFICATIONS [2061344-88-3]
Catalog
SLK-S7330
Brand
Selleck
CAS
2061344-88-3
DESCRIPTION [2061344-88-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 590.14 |
| Molecular Formula | C20H30ClN3O2S3.CF3COOH |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.6945 mL | 8.4726 mL | 16.9451 mL |
| 5 mM | 0.3389 mL | 1.6945 mL | 3.3890 mL |
| 10 mM | 0.1695 mL | 0.8473 mL | 1.6945 mL |
| 50 mM | 0.0339 mL | 0.1695 mL | 0.3389 mL |
Description
6H05 is a selective, and allosteric inhibitor of oncogenic .
Targets
| K-Ras(G12C) [1] |
In vitro
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras. . Furthermore, 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors.
References
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