Overview MDL MFCD05144768 Molecular Weight 277.38 Molecular Formula C15H19NO2S SMILES CC1=CN(S(=O)(C2=C(C)C=C(C)C=C2C)=O)C(C)=C1
For research use only.
Storage 3 years,-20°C,powder
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions Concentration Volume Mass 1 mg 5 mg 10 mg 1 mM 3.6052 mL 18.0258 mL 36.0516 mL 5 mM 0.7210 mL 3.6052 mL 7.2103 mL 10 mM 0.3605 mL 1.8026 mL 3.6052 mL 50 mM 0.0721 mL 0.3605 mL 0.7210 mL
Description HJC0350 is a potent and selective inhibitor with of 0.3 μM, exhibiting no inhibition on Epac1.
In vitro HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2.
