[CAS NO. 1285702-20-6] ML167

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PRODUCTS SPECIFICATIONS [1285702-20-6]

Catalog

SLK-S7509

Brand

Selleck

CAS

1285702-20-6

MDL	MFCD27978379
Molecular Weight	335.36
Molecular Formula	C19H17N3O3
SMILES	OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

ML167 (CID 44968231) is a highly selective inhibitor with of 136 nM, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B.

CLK4 ^[1]	CLK1 ^[1]	CLK2 ^[1]	Dyrk1B ^[1]
136 nM	1522 nM	1648 nM	4420 nM

ML167, as a probe of Clk4, shows high cell permeability in a Caco-2 assay.