[CAS NO. 1334719-95-7] Telacebec (Q203)
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PRODUCTS SPECIFICATIONS [1334719-95-7]
Distributor
Catalog
SLK-S7739
Brand
Selleck
CAS
1334719-95-7
DESCRIPTION [1334719-95-7]
Overview
| MDL | MFCD28502122 |
|---|---|
| Molecular Weight | 557.01 |
| Molecular Formula | C29H28ClF3N4O2 |
| SMILES | O=C(C1=C(CC)N=C2C=CC(Cl)=CN21)NCC3=CC=C(N4CCC(C5=CC=C(OC(F)(F)F)C=C5)CC4)C=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.7953 mL | 8.9765 mL | 17.9530 mL |
| 5 mM | 0.3591 mL | 1.7953 mL | 3.5906 mL |
| 10 mM | 0.1795 mL | 0.8976 mL | 1.7953 mL |
| 50 mM | - | - | - |
Description
Telacebec (Q203, IAP6) is a novel antituberculosis drug that targets cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
Targets
| Mycobacterium tuberculosis H37Rv [2] |
| 2.7 nM(MIC50) |
In vitro
References
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