[CAS NO. 979-92-0] S-Adenosyl-L-homocysteine (SAH)

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PRODUCTS SPECIFICATIONS [979-92-0]

Catalog

SLK-S7868

Brand

Selleck

CAS

979-92-0

DESCRIPTION [979-92-0]

Overview

MDL	MFCD00037388
Molecular Weight	384.41
Molecular Formula	C14H20N6O5S
SMILES	O[C@H]1[C@](N2C=3C(N=C2)=C(N)N=CN3)(O[C@H](CSCC[C@@H](C(O)=O)N)[C@H]1O)[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.6014 mL	13.0069 mL	26.0139 mL
5 mM	0.5203 mL	2.6014 mL	5.2028 mL
10 mM	0.2601 mL	1.3007 mL	2.6014 mL
50 mM	0.0520 mL	0.2601 mL	0.5203 mL

Description

S-Adenosyl-L-homocysteine (SAH, S-Adenosylhomocysteine, AdoHcy, Formycinylhomocysteine) is an inhibitor for with IC50 of 0.9 μM.

Targets

METTL3-14 ^[1]
(Cell-free assay)

0.9 μM

In vitro

S-Adenosyl-L-homocysteine (SAH) shows strong inhibitory effects on METTL3-14 activity with an IC50 value of 0.9 ± 0.1 μM. While the presence of S-Adenosyl-L-homocysteine has no significant effects on ALKBH5 activity.

References

[1] Fengling Li, et al. J Biomol Screen. 2016 Mar;21(3):290-7.

Synonyms

L-Homocysteine, S-(5′-deoxyadenosin-5′-yl)-

Adenosine, 5′-S-(3-amino-3-carboxypropyl)-5′-thio-, L-

Homocysteine, S-adenosyl-, L-

S-(5′-Deoxyadenosin-5′-yl)-L-homocysteine

Adenosylhomocysteine

S-Adenosylhomocysteine

Adenosyl-L-homocysteine

S-Adenosyl-L-homocysteine

L-S-Adenosylhomocysteine

S-(5′-Adenosyl)-L-homocysteine

SAH

SAH (S-Adenosylhomocysteine)