[CAS NO. 1613028-81-1] SR9243
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [1613028-81-1]
Store
Catalog
SLK-S7934
Brand
Selleck
CAS
1613028-81-1
DESCRIPTION [1613028-81-1]
Overview
| MDL | MFCD29049514 |
|---|---|
| Molecular Weight | 626.62 |
| Molecular Formula | C31H32BrNO4S2 |
| SMILES | BrC1=CC(CCN(S(C2=C(C)C=C(C)C=C2C)(=O)=O)CC(C=C3)=CC=C3C4=CC(S(=O)(C)=O)=CC=C4)=CC=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
SR9243 is a potent and selective inverse agonist.
Targets
| LXR [1] |
In vitro
In HEK293 cells expressing LXRs, SR9243 inhibits LXR activation by enhancing LXR-corepressor recruitment. In a variety of cancer cell types, SR9243 reduces cancer cell viability, induces apoptotic cell death, and sensitizes cancer cells to chemotherapeutic treatments.
In vivo
In Ob/Ob mice fed a high-fat diet, SR9243 (60 mg/kg, i.p.) inhibits LXR-dependent lipogenic enzyme gene expression and tumor growth.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.