[CAS NO. 175135-47-4] O4I1

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PRODUCTS SPECIFICATIONS [175135-47-4]

Catalog

SLK-S7943

Brand

Selleck

CAS

175135-47-4

DESCRIPTION [175135-47-4]

Overview

MDL	MFCD00067778
Molecular Weight	253.30
Molecular Formula	C16H15NO2
SMILES	O(CC1=CC=C(OC)C=C1)C2=CC=C(CC#N)C=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.9479 mL	19.7394 mL	39.4789 mL
5 mM	0.7896 mL	3.9479 mL	7.8958 mL
10 mM	0.3948 mL	1.9739 mL	3.9479 mL
50 mM	0.0790 mL	0.3948 mL	0.7896 mL

Description

O4I1 is a potent inducer.

Targets

OCT4 ^[1]

OCT3 ^[1]

In vitro

O4I1 enhances Oct3/4 gene expression by approximately 2.5- and 4-fold at 10 μM and 20 μM, respectively, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation.

References

[1] Cheng X, et al. J Med Chem. 2015, 58(12), 4976-4983.

Synonyms

Benzeneacetonitrile, 4-[(4-methoxyphenyl)methoxy]-

4-[(4-Methoxyphenyl)methoxy]benzeneacetonitrile

[4-[(4-Methoxybenzyl)oxy]phenyl]acetonitrile

2-(4-[(4-Methoxybenzyl)oxy]phenyl)acetonitrile

2-[4-[(4-Methoxyphenyl)methoxy]phenyl]acetonitrile