[CAS NO. 165682-93-9] O4I2

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PRODUCTS SPECIFICATIONS [165682-93-9]

Catalog

SLK-S7944

Brand

Selleck

CAS

165682-93-9

DESCRIPTION [165682-93-9]

Overview

MDL	MFCD08166530
Molecular Weight	282.75
Molecular Formula	C12H11ClN2O2S
SMILES	N(C1=NC(C(OCC)=O)=CS1)C2=CC=C(Cl)C=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.5367 mL	17.6835 mL	35.3669 mL
5 mM	0.7073 mL	3.5367 mL	7.0734 mL
10 mM	0.3537 mL	1.7683 mL	3.5367 mL
50 mM	0.0707 mL	0.3537 mL	0.7073 mL

Description

O4I2 is a potent inducer, which is suitable for iPSC generation.

Targets

OCT3 ^[1]

OCT4 ^[1]

In vitro

O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog.

Synonyms

4-Thiazolecarboxylic acid, 2-[(4-chlorophenyl)amino]-, ethyl ester

Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate