[CAS NO. 2070014-87-6] MRT68921 HCl

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PRODUCTS SPECIFICATIONS [2070014-87-6]

Catalog

SLK-S7949

Brand

Selleck

CAS

2070014-87-6

MDL	MFCD30187515
Molecular Weight	434.58 (free base)
Molecular Formula	C25H34N6O·xHCl
SMILES	O=C(C1CCC1)NCCCNC2=NC(NC3=CC4=C(CN(C)CC4)C=C3)=NC=C2C5CC5.[H]Cl

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

MRT68921 is a potent and dual autophagy kinase inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.

ULK2 ^[1] (Cell-free assay)	ULK1 ^[1] (Cell-free assay)
1.1 nM	2.9 nM

MRT68921 specifically disrupts autophagosome maturation and thus blocks autophagic flux through ULK1 inhibition.