[CAS NO. 1306760-87-1]  Ozanimod (RPC1063)

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PRODUCTS SPECIFICATIONS [1306760-87-1]

Catalog
SLK-S7952
Brand
Selleck
CAS
1306760-87-1

DESCRIPTION [1306760-87-1]

Overview

MDLMFCD28386168
Molecular Weight404.46
Molecular FormulaC23H24N4O3
SMILESN(CCO)[C@@H]1C=2C(=C(C=CC2)C=3N=C(ON3)C4=CC(C#N)=C(OC(C)C)C=C4)CC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.4724 mL12.3622 mL24.7243 mL
5 mM0.4945 mL2.4724 mL4.9449 mL
10 mM0.2472 mL1.2362 mL2.4724 mL
50 mM0.0494 mL0.2472 mL0.4945 mL

Description

Ozanimod (RPC1063) is a selective oral modulator. Phase 3.

Targets

S1P1R [1]
(Cell-free assay)
S1P5R [1]
(Cell-free assay)
0.41 nM(EC50)11 nM(EC50)

In vitro

In S1P1R-HEK293T cells, Ozanimod induces sustained S1P1R internalization and degradation.


Synonyms

Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-
5-[3-[(1S)-2,3-Dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)benzonitrile
Ozanimod
RPC 1063
5-[3-[1-(S)-(2-Hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-isopropoxybenzonitrile
Zeposia