Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
HA15 is a molecule that targets specifically also known as or . HA15 displays activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
HA15 induces ER stress leading to cancer cell death in vitro and overcomes BRAF inhibitor resistance in melanoma cells.
In vivo
HA15 induces ER stress leading to cancer cell death and exhibits strong efficacy in xenograft mouse models with melanoma cells either sensitive or resistant to BRAF inhibitors.
