[CAS NO. 473727-83-2] Navarixin (SCH-527123)
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PRODUCTS SPECIFICATIONS [473727-83-2]
Catalog
SLK-S8506
Brand
Selleck
CAS
473727-83-2
DESCRIPTION [473727-83-2]
Overview
| MDL | MFCD16628072 |
|---|---|
| Molecular Weight | 397.42 |
| Molecular Formula | C21H23N3O5 |
| SMILES | O=C(N(C)C)C1=CC=CC(NC2=C(N[C@@H](C3=CC=C(C)O3)CC)C(C2=O)=O)=C1O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.5162 mL | 12.5811 mL | 25.1623 mL |
| 5 mM | 0.5032 mL | 2.5162 mL | 5.0325 mL |
| 10 mM | 0.2516 mL | 1.2581 mL | 2.5162 mL |
| 50 mM | 0.0503 mL | 0.2516 mL | 0.5032 mL |
Description
Navarixin (SCH-527123, MK-7123, PS-291822) is a potent, orally bioavailable antagonist with IC50 values of 2.6 nM and 36 nM, respectively.
In vitro
Navarixin (SCH-527123, MK-7123, PS-291822) is a potent, orally bioavailable CXCR2/CXCR1 antagonist with IC50 values of 2.6 nM and 36 nM, respectively.
References
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