[CAS NO. 432001-69-9]  Skp2 inhibitor C1 (SKPin C1)

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PRODUCTS SPECIFICATIONS [432001-69-9]

Catalog
SLK-S8652
Brand
Selleck
CAS
432001-69-9

DESCRIPTION [432001-69-9]

Overview

MDL-
Molecular Weight465.34
Molecular FormulaC18H13BrN2O4S2
SMILESO=C(O)COC1=CC=C(Br)C=C1/C=C(SC(N2CC3=CC=CN=C3)=S)/C2=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of by reducing p27 binding through key compound-receptor contacts.

Targets

p27 degradation [1]

In vitro

Skp2 inhibitor C1 treatment of MCF-7 breast cancer cells lines does not increase, but rather decrease the percentage of cells in G1 while increasing the G2/M population.