[CAS NO. 1303420-67-8] PLX5622

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PRODUCTS SPECIFICATIONS [1303420-67-8]

Catalog

SLK-S8874

Brand

Selleck

CAS

1303420-67-8

MDL	MFCD32201039
Molecular Weight	395.41
Molecular Formula	C21H19F2N5O
SMILES	CC1=CN=C(C2=C1)NC=C2CC3=C(N=C(C=C3)NCC4=CC(F)=CN=C4OC)F

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

PLX5622 is a highly selective inhibitor (IC50 < 10 nmol/L), showing > 20-fold selectivity over KIT and FLT3.

CSF-1R ^[1] (Cell-free assay)	FLT3 ^[1] (Cell-free assay)	KIT ^[1] (Cell-free assay)	AURKC ^[1] (Cell-free assay)	KDR ^[1] (Cell-free assay)
0.016 μM	0.39 μM	0.86 μM	1 μM	1.1 μM

PLX5622 is a highly selective CSF-1R inhibitor (IC50 < 10 nmol/L), showing > 20-fold selectivity over KIT and FLT3.