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Catalog:
SLK-S8905
Brand:
Selleck
CAS:
2289690-31-7
Overview
MDL
-
Molecular Weight
594.86
Molecular Formula
C26H16ClF9N2O2
SMILES
-
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
1.6811 mL
8.4053 mL
16.8107 mL
5 mM
0.3362 mL
1.6811 mL
3.3621 mL
10 mM
0.1681 mL
0.8405 mL
1.6811 mL
50 mM
0.0336 mL
0.1681 mL
0.3362 mL
Description
MYCi361 is a inhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 μM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy.
