[CAS NO. 2222844-89-3] Camizestrant (AZD9833)
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PRODUCTS SPECIFICATIONS [2222844-89-3]
Catalog
SLK-S8958
Brand
Selleck
CAS
2222844-89-3
DESCRIPTION [2222844-89-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 476.51 |
| Molecular Formula | C24H28F4N6 |
| SMILES | FC(F)(F)CN1[C@H](C2=CC=C(NC3CN(CCCF)C3)C=N2)C4=C(C5=C(NN=C5)C=C4)C[C@H]1C |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.0986 mL | 10.4930 mL | 20.9859 mL |
| 5 mM | 0.4197 mL | 2.0986 mL | 4.1972 mL |
| 10 mM | 0.2099 mL | 1.0493 mL | 2.0986 mL |
| 50 mM | 0.0420 mL | 0.2099 mL | 0.4197 mL |
Description
Camizestrant (AZD9833) is an orally available and selective antagonist with antineoplastic activity.
Targets
| ER [1] |
In vitro
AZD9833 is demonstrated to be a highly potent selective estrogen receptor degraders (SERD) that shows a pharmacological profile comparable to fulvestrant in its ability to degrade ERα in both MCF-7 and CAMA-1 cell lines.
References
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