[CAS NO. 384859-58-9] BCH001
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PRODUCTS SPECIFICATIONS [384859-58-9]
Catalog
SLK-S8977
Brand
Selleck
CAS
384859-58-9
DESCRIPTION [384859-58-9]
Overview
| MDL | MFCD02932975 |
|---|---|
| Molecular Weight | 420.34 |
| Molecular Formula | C20H15F3N2O5 |
| SMILES | O=C(C1=C(NC2=CC=CC=C2C(O)=O)C3=CC(OC(F)(F)F)=CC=C3N=C1)OCC |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.3790 mL | 11.8951 mL | 23.7903 mL |
| 5 mM | 0.4758 mL | 2.3790 mL | 4.7581 mL |
| 10 mM | 0.2379 mL | 1.1895 mL | 2.3790 mL |
| 50 mM | 0.0476 mL | 0.2379 mL | 0.4758 mL |
Description
BCH001 is a specific inhibitor that restores telomerase activity and telomere length in dyskeratosis congenita (DC) patient induced pluripotent stem cells. PAPD5 is a noncanonical poly(A) polymerase with an unusual RNA-binding motif.
Targets
| PAPD5 [1] |
In vitro
BCH001 is a specific PAPD5 inhibitor that restores telomerase activity and telomere length in DC patient induced pluripotent stem cells.
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