Overview
MDL | MFCD28385769 |
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Molecular Weight | 513.07 |
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Molecular Formula | C27H37ClN6O2 |
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SMILES | N#CC1(CNC2=CC=CC(C3=CC(N[C@H]4CC[C@H](N[C@H](C)COC)CC4)=NC=C3Cl)=N2)CCOCC1 |
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For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
NVP-2, a potent, selective, non-neurotoxic and ATP-competitive inhibitor with IC50 of 0.514 nM for CDK9/CycT activity and induces cell .
Targets
CDK9/CycT [1] (Cell-free assay) |
0.514 nM |
In vitro
NVP-2 selectively inhibits CDK9. NVP-2 exhibits anti-proliferative effects and transcription inhibition. NVP-2 diminishes elongating polymerase II.