[CAS NO. 1263373-43-8]  NVP-2

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PRODUCTS SPECIFICATIONS [1263373-43-8]

Catalog
SLK-S8981
Brand
Selleck
CAS
1263373-43-8

DESCRIPTION [1263373-43-8]

Overview

MDLMFCD28385769
Molecular Weight513.07
Molecular FormulaC27H37ClN6O2
SMILESN#CC1(CNC2=CC=CC(C3=CC(N[C@H]4CC[C@H](N[C@H](C)COC)CC4)=NC=C3Cl)=N2)CCOCC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

NVP-2, a potent, selective, non-neurotoxic and ATP-competitive inhibitor with IC50 of 0.514 nM for CDK9/CycT activity and induces cell .

Targets

CDK9/CycT [1]
(Cell-free assay)
0.514 nM

In vitro

NVP-2 selectively inhibits CDK9. NVP-2 exhibits anti-proliferative effects and transcription inhibition. NVP-2 diminishes elongating polymerase II.