[CAS NO. 2086-83-1]  Berberine

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PRODUCTS SPECIFICATIONS [2086-83-1]

Distributor
Catalog
SLK-S9046
Brand
Selleck
CAS
2086-83-1

DESCRIPTION [2086-83-1]

Overview

MDLMFCD01175817
Molecular Weight336.36
Molecular FormulaC20H18NO4
SMILESO(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9730 mL14.8650 mL29.7301 mL
5 mM0.5946 mL2.9730 mL5.9460 mL
10 mM0.2973 mL1.4865 mL2.9730 mL
50 mM0.0595 mL0.2973 mL0.5946 mL

Description

Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.

In vitro

In 3T3-L1 adipocytes, the treatment of 12 μM or 20 μM berberine combined with 25 μM resveratrol shows more significant inhibition of lipid accumulation compared with individual compounds. The combination of berberine with resveratrol significantly increases the low-density-lipoprotein receptor expression in HepG2 cells to a level about one-fold higher in comparison to individual compounds.


Synonyms

Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-
Umbellatine
Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
Berberine
Berbericine
Berberin
Umbellatin
Thalsine
Majarine
Berberone