[CAS NO. 2174-59-6] Demethylnobiletin

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PRODUCTS SPECIFICATIONS [2174-59-6]

Catalog

SLK-S9421

Brand

Selleck

CAS

2174-59-6

DESCRIPTION [2174-59-6]

Overview

MDL	MFCD08458849
Molecular Weight	388.37
Molecular Formula	C20H20O8
SMILES	O(C)C1=C2C(=C(O)C(OC)=C1OC)C(=O)C=C(O2)C3=CC(OC)=C(OC)C=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Demethylnobiletin (5-Demethylnobiletin) is a unique flavonoid found in citrus fruits with potential chemopreventive effects against human cancers.5-Demethylnobiletin is a direct inhibitor of with IC50 of 0.1 μM, without affecting the expression of COX-2. 5-Demethylnobiletin has anti-inflammatory activity, inhibits formation in rat neutrophils and elastase release in human neutrophils with IC50 of 0.35 μM.

Synonyms

4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-

Flavone, 5-hydroxy-3′,4′,6,7,8-pentamethoxy-

2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one

5-O-Demethylnobiletin

5-Hydroxy-6,7,8,3′,4′-pentamethoxyflavone

5-Hydroxy-3′,4′,6,7,8-pentamethoxyflavone

5-O-Desmethylnobiletin

5-Desmethylnobiletin

5-Demethylnobiletin

NSC 618927

2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxychromen-4-one