[CAS NO. 2378173-15-8] PF-06928215
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PRODUCTS SPECIFICATIONS [2378173-15-8]
Catalog
SLK-S9615
Brand
Selleck
CAS
2378173-15-8
DESCRIPTION [2378173-15-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 380.40 |
| Molecular Formula | C20H20N4O4 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
PF-06928215 is a high affinity inhibitor of with an IC50 of 4.9 μM.
Targets
| cGAS [1] |
| 4.9 μM |
In vitro
PF-06928215, a high affinity inhibitor of Cyclic GMP-AMP synthase (cGAS), has no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression via a luciferase reporter. PF-06928215 has minimal effect on cell viability.[1]
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