[CAS NO. 1353900-92-1] Pibrentasvir (ABT-530)
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PRODUCTS SPECIFICATIONS [1353900-92-1]
Catalog
SLK-S9641
Brand
Selleck
CAS
1353900-92-1
DESCRIPTION [1353900-92-1]
Overview
| MDL | MFCD30747902 |
|---|---|
| Molecular Weight | 1113.18 |
| Molecular Formula | C57H65F5N10O8 |
| SMILES | FC1=C([C@@H]2N([C@H](CC2)C3=C(F)C=C4C(NC([C@@H]5CCCN5C([C@@H](NC(OC)=O)[C@H](OC)C)=O)=N4)=C3)C6=CC(F)=C(C(F)=C6)N7CCC(CC7)C8=CC=C(C=C8)F)C=C9C(N=C(N9)[C@@H]%10CCCN%10C([C@@H](NC(OC)=O)[C@H](OC)C)=O)=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 0.8983 mL | 4.4916 mL | 8.9833 mL |
| 5 mM | 0.1797 mL | 0.8983 mL | 1.7967 mL |
| 10 mM | 0.0898 mL | 0.4492 mL | 0.8983 mL |
| 50 mM | 0.0180 mL | 0.0898 mL | 0.1797 mL |
Description
Pibrentasvir (ABT-530) is a novel and pan-genotypic inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.
Targets
In vitro
Pibrentasvir is a next-generation HCV NS5A inhibitor with potent and pan-genotypic activity, and it maintains activity against common amino acid substitutions of HCV genotypes 1 to 6 that are known to confer resistance to currently approved NS5A inhibitors.
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