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Catalog:
SLK-S9790
Brand:
Selleck
CAS:
2369979-68-8
Overview
MDL
-
Molecular Weight
358.84
Molecular Formula
C19H20ClFN4
SMILES
-
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
2.7868 mL
13.9338 mL
27.8676 mL
5 mM
0.5574 mL
2.7868 mL
5.5735 mL
10 mM
0.2787 mL
1.3934 mL
2.7868 mL
50 mM
0.0557 mL
0.2787 mL
0.5574 mL
Description
JHU37160 is a agonist with Ki of 1.9 nM and 3.6 nM for and in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
JHU37160 is a potent DREADD agonist with high potency and efficacy in fluorescent and BRET-based assays in HEK-293 cells, whereas no responses are observed in untransfected HEK-293 cells.