Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
3.2291 mL
16.1457 mL
32.2914 mL
5 mM
0.6458 mL
3.2291 mL
6.4583 mL
10 mM
0.3229 mL
1.6146 mL
3.2291 mL
50 mM
0.0646 mL
0.3229 mL
0.6458 mL
Description
DTHIB (Direct Targeted HSF1 InhiBitor) is a direct and selective inhibitor of with Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB exhibits potently anticancer activities.
Direct Targeted HSF1 InhiBitor (DTHIB) physically engages HSF1 and selectively stimulates degradation of nuclear HSF1. DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
