Please click "REQUEST A QUOTE" button if there is no stock, or
you need other sizes or custom synthesis.
Catalog:
SLK-S9819
Brand:
Selleck
CAS:
218137-86-1
Overview
MDL
-
Molecular Weight
254.32
Molecular Formula
C14H22O4
SMILES
C(CCCCCCC)C1C(C(O)=O)C(=C)C(=O)O1
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
1 mg
5 mg
10 mg
1 mM
3.9321 mL
19.6603 mL
39.3205 mL
5 mM
0.7864 mL
3.9321 mL
7.8641 mL
10 mM
0.3932 mL
1.9660 mL
3.9321 mL
50 mM
0.0786 mL
0.3932 mL
0.7864 mL
Description
C75 (4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid) , a more stable synthetic mimic of cerulenin, inhibits with an IC50 of 15.53 μM and has potential therapeutic effects in several cancer models. C75 is also a potent CPT1A activator.
C75, the competitive irreversible fatty acid synthase (FASN) inhibitor, possesses radiosensitizing activity in prostate cancer cell lines that is affected by the availability of fatty acids, also increases expression of fatty acid transporter proteins FATP1 and CD36.
