[CAS NO. 1123231-07-1]  WAY-262611

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PRODUCTS SPECIFICATIONS [1123231-07-1]

Catalog
SLK-S9828
Brand
Selleck
CAS
1123231-07-1

DESCRIPTION [1123231-07-1]

Overview

MDLMFCD20527803
Molecular Weight318.42
Molecular FormulaC20H22N4
SMILESNCC1CCN(C2=NC=CC(C3=CC=C4C=CC=CC4=C3)=N2)CC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.1405 mL15.7025 mL31.4051 mL
5 mM0.6281 mL3.1405 mL6.2810 mL
10 mM0.3141 mL1.5703 mL3.1405 mL
50 mM0.0628 mL0.3141 mL0.6281 mL

Description

WAY-262611 (BML-WN110, Compound 5) is a agonist that increases bone formation rate with EC50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also an inhibitor of .

Targets

DKK1 [2]β-Catenin [1]
(TCF-Luciferase assay)
0.63 μM(EC50)

In vitro

WAY-262611, the DKK1 inhibitor, blocks DKK1 and restores the GDF5 reduced MMP13 gene expression.