[CAS NO. 2416874-75-2] KB-0742 Dihydrochloride
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PRODUCTS SPECIFICATIONS [2416874-75-2]
Catalog
SLK-S9901
Brand
Selleck
CAS
2416874-75-2
DESCRIPTION [2416874-75-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 360.33 |
| Molecular Formula | C16H25N5.2ClH |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7752 mL | 13.8762 mL | 27.7523 mL |
| 5 mM | 0.5550 mL | 2.7752 mL | 5.5505 mL |
| 10 mM | 0.2775 mL | 1.3876 mL | 2.7752 mL |
| 50 mM | 0.0555 mL | 0.2775 mL | 0.5550 mL |
Targets
| CDK9/cyclin T1 [1] |
| 6 nM |
In vitro
KB-0742 rapidly downregulates nascent transcription, preferentially depleting short half-life transcripts and AR-driven oncogenic programs in 22Rv1 cells. [1]
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