[CAS NO. 2573912-32-8] CU-CPD107
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:
PRODUCTS SPECIFICATIONS [2573912-32-8]
Store
Catalog
SLK-S9937
Brand
Selleck
CAS
2573912-32-8
DESCRIPTION [2573912-32-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 400.26 |
| Molecular Formula | C16H21IN2O2 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a signaling inhibitor (IC50=13.7 μM). In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling.
Targets
| TLR8 [1] (in HEK-Blue hTLR8 cells) |
| 13.7 μM |
In vitro
CU-CPD107, a tetrasubstituted imidazole, inhibits R848-induced TLR8 signaling and shows unexpected synergistic agonist activities in the presence of ssRNA, while CU-CPD107 alone is unable to influence TLR8 signaling.
Powered by Arctom Copyright © 2026 Arctom. All rights
reserved.