According to public information, mPEG-DMG (PEG 2000 DMG) is one of the excipients of the COVID-19 vaccine, which can help reduce antibody association (opsonization) by serum proteins and clearance by phagocytes thus conferring longer systemic circulation.
Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at [email protected] and start using a superior product for your next product R&D project.
References:
1. Lipid Nanoparticles─From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement, Rumiana Tenchov, Robert Bird, Allison E. Curtze, and Qiongqiong Zhou, ACS Nano 2021 15 (11), 16982-17015, DOI: 10.1021/acsnano.1c04996
2. Roh, H., & Oh, K. (2021). Brief Review on the Processes for RNA-Platform Vaccine Production. Journal of the Korea Convergence Society , 12 (8), 179–186. https://doi.org/10.15207/JKCS.2021.12.8.179