Tetraethylene glycol monotosylate (OH-PEG4-Tos) is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). And it also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.
Biopharma PEG offers a wide range of PEG products from lab to commercial scale in both non-GMP and GMP grades. Email at [email protected] and start using a superior product for your next product R&D project.
References:
1. Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16(7):763-72.