
New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.
MCE owns a unique collection of 3,163 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. MCE FDA-Approved Drug Library is a good tool for drug repurposing which could dramatically accelerate drug development.
For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.
• A unique collection of 3,163 approved drugs for high throughput screening (HTS) and high content screening (HCS).
• Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.
• A useful tool for researching new targets of marketed old drugs.
• All compounds have been approved by the FDA, EMA and other countries.
• Structurally diverse, bioactive, and cell permeable.
• More detailed compound information with structure, IC50, and brief introduction.
• NMR and HPLC validated ensure high purity.
• All compounds are in stock and continuously updated.
| FDA-Approved Drug Library | FDA-Approved Drug Library Mini (Cat. No.: HY-L022M) | |
|---|---|---|
| Size | 30, 50, 100, and 200 μL in DMSO | 10 μL in DMSO |
| Package | 96-Well Format Sample Storage Tube With Screw Cap | 96-well microplate with peelable foil seal |
| Delivery Date | About one month | Within three days |
| Price Per Set | High | Low |
| Preparation For Use | If there is no robot, each tube needs to be manually opened | Tear off the seal film on the microplate |
Formulation:
A collection of 3,163 marketed drugs supplied as pre-dissolved Solutions or Solid
Solution: 3,069 compounds supplied in 10 mM solution, 65 compounds supplied in 2 mM solution, 29 compounds supplied in 3 mg/mL solution.
Layout:
96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice or dry ice