[CAS NO. 100900-16-1]  1,4-Chrysenequinone

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PRODUCTS SPECIFICATIONS [100900-16-1]

Catalog
HY-111441
Brand
MCE
CAS
100900-16-1

DESCRIPTION [100900-16-1]

Overview

MDLMFCD00009941
Molecular Weight258.27
Molecular FormulaC18H10O2
SMILESO=C(C1=C2C=CC3=C1C=CC4=CC=CC=C43)C=CC2=O

For research use only. We do not sell to patients.

Summary

1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor ( AhR ).


IC50 & Target

AhR [1]


In Vitro

1,4-Chrysenequinone shows significant AhR ligand activity, with EC TCDD25 s (concentration equivalent with 25% of TCDD max) of 9.7 nM and 1.9 μM in yeast and mouse hepatoma cell systems, respectively [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 3.33 mg/mL ( 12.89 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8719 mL 19.3596 mL 38.7192 mL
5 mM 0.7744 mL 3.8719 mL 7.7438 mL
10 mM 0.3872 mL 1.9360 mL 3.8719 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 0.5 mg/mL (1.94 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.