[CAS NO. 102029-68-5] Adenosine 5′-monophosphoramidate sodium

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PRODUCTS SPECIFICATIONS [102029-68-5]

Catalog

HY-N7517

Brand

MCE

CAS

102029-68-5

DESCRIPTION [102029-68-5]

Overview

MDL	MFCD00042776
Molecular Weight	368.22
Molecular Formula	C10H14N6NaO6P
SMILES	O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](N)(O[Na])=O)([H])N2C3=NC=NC(N)=C3N=C2

For research use only. We do not sell to patients.

Summary

Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : ≥ 25 mg/mL ( 67.89 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7158 mL	13.5788 mL	27.1577 mL
5 mM	0.5432 mL	2.7158 mL	5.4315 mL
10 mM	0.2716 mL	1.3579 mL	2.7158 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] H Iizuka, et al.Adenosine and Adenine Nucleotides Stimulation of Skin (Epidermal) Adenylate Cyclase. Biochim Biophys Acta. 1976 Oct 22;444(3):685-93.