MDL | - |
---|---|
Molecular Weight | 151.16 |
Molecular Formula | C8H9NO2 |
SMILES | O=C(C)NC1=CC=C(O)C=C1 |
COX-2 25.8 μM (IC 50 ) |
COX-1 113.7 μM (IC 50 ) |
In vitro , acetaminophen elicites a 4.4-fold selectivity toward COX-2 inhibition (IC 50 113.7 μM for COX-1; IC 50 25.8 μM for COX-2). Following oral administration of the drug, maximal ex vivo inhibitions are 56% (COX-1) and 83% (COX-2). Acetaminophen plasma concentrations remaine above the in vitro IC 50 for COX-2 for at least 5 h postadministration. Ex vivo IC 50 values (COX-1: 105.2 μM; COX-2: 26.3 μM) of acetaminophen compared favorably with its in vitro IC 50 values. In contrast to previous concepts, acetaminophen inhibited COX-2 by more than 80%, i.e., to a degree comparable to nonsteroidal antiinflammatory drugs (NSAIDs) and selective COX-2 inhibitors. However, a >95% COX-1 blockade relevant for suppression of platelet function is not achieved [1] . MTT assay shows that Acetaminophen (APAP) in a dose of 50 mM significantly (p<0.001) reduces cell viability to 61.5±6.65%. Interestingly, the significant (p<0.01) increase in cell viability to 79.7±2.47% is observed in the Acetaminophen/HV110 co-treated cells, compared to Acetaminophen treated cells [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Administering Acetaminophen (250 mg/kg, orally) to the mice causes significant (p<0.001) liver damage and necrosis of cells as evidenced by the elevated serum hepatic enzymes alanine aminotransferase (ALT), aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (γGT) compared with normal group. Conversely, effects of pretreatment with different doses of citral (125, 250, and 500 mg/kg) exhibited a significant (p<0.05) decrease in serum activities of ALT (91.79%, 93.07%, and 95.61%, resp.), AST (93.40%, 91.89%, and 96.52%, resp.), ALP (39.29%, 37.07%, and 59.80%, resp.), and γGT (92.83%, 91.59%, and 93.0%, resp.), when compared to the Acetaminophen group. Similar results were found in pretreatment with SLM on the activity of ALT (95.90%), AST (95.03%), ALP (70.52%), and γGT (92.69%) [3] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
NCT Number | Sponsor | Condition | Start Date | Phase |
---|---|---|---|---|
NCT03368664 | Genzyme, a Sanofi Company|Sanofi |
Multiple Sclerosis
|
October 24, 2017 | Phase 3 |
NCT03145467 | Pamukkale University |
Acute Migraine Headache
|
January 2016 | Phase 4 |
NCT05523102 | Indonesia University|Dr Cipto Mangunkusumo General Hospital |
Pain, Postoperative
|
March 31, 2022 | Phase 4 |
NCT02439034 | Centre Oscar Lambret|Santelys Association |
Uterine Cervical Cancer|Upper Aerodigestive Tract Neoplasms
|
February 2015 | Phase 2 |
NCT01466348 | GlaxoSmithKline |
Common Cold
|
February 2011 | Phase 4 |
NCT00534651 | University of Zurich |
Coronary Arteriosclerosis|Endothelial Function
|
November 2006 | Phase 4 |
NCT04536051 | University of Oxford |
Coronavirus
|
June 2, 2020 | Phase 3 |
NCT03243006 | University of Monastir |
Acute Pain
|
January 1, 2016 | Not Applicable |
NCT02108990 | Ohio State University|National Center for Advancing Translational Sciences (NCATS)|National Center for Research Resources (NCRR) |
Borderline Personality Disorder
|
September 2013 | Phase 2 |
NCT00474721 | University of California, San Diego |
Pain
|
November 2002 | Not Applicable |
NCT00720811 | Mbarara University of Science and Technology|Makerere University|Ministry of Health, Uganda|Navrongo Health Research Centre, Ghana|National Malaria Research and Training Centre, Burkina Faso |
Malaria|Pneumonia
|
October 2009 | Not Applicable |
NCT01944085 | KK Women´s and Children´s Hospital |
Elbow Fracture
|
October 2008 | Not Applicable |
NCT02268058 | McMaster Children´s Hospital |
Concussion|Headache
|
October 2013 | Not Applicable |
NCT03223506 | Poitiers University Hospital |
Brain Injured Patients
|
March 23, 2013 | Phase 1 |
NCT02359305 | Arlyne Thung|Nationwide Children´s Hospital |
Pyloric Stenosis
|
June 2014 | |
NCT01527942 | Saint Francis Care |
Obesity|Pain
|
March 2012 | Not Applicable |
NCT02832687 | Rutgers, The State University of New Jersey|Mallinckrodt |
Recovery Following Cholecystectomy
|
June 19, 2017 | Phase 4 |
NCT04532931 | Shin Poong Pharmaceutical Co. Ltd.|Medicines for Malaria Venture |
COVID-19
|
September 3, 2020 | Phase 2 |
NCT01231139 | Dr. M.K. Saxena|The George Institute|The University of New South Wales|Royal Brisbane and Women´s Hospital|South East Sydney and Illawarra Area Health Service |
Traumatic Brain Injury
|
October 2010 | Phase 2 |
NCT01476189 | GlaxoSmithKline |
Healthy Subjects
|
November 2009 | Phase 1 |
NCT02711826 | National Institute of Allergy and Infectious Diseases (NIAID)|Clinical Trials in Organ Transplantation |
Kidney Transplant|Adult Living Donor Kidney Transplant Recipients|Renal Transplant|Living Kidney Donor
|
September 20, 2016 | Phase 1|Phase 2 |
NCT01517555 | Novo Nordisk A+S |
Diabetes|Diabetes Mellitus, Type 2
|
October 2006 | Phase 1 |
NCT02393339 | Hadassah Medical Organization |
Pain, Postoperative|Analgesia
|
February 1, 2017 | Early Phase 1 |
NCT01535001 | Northern Orthopaedic Division, Denmark|The Danish Rheumatism Association|Association of Danish Physiotherapists |
Osteoarthritis of the Knee
|
February 2012 | Not Applicable |
NCT00261560 | Johnson & Johnson Consumer and Personal Products Worldwide |
Sprains and Strains|Pain
|
Phase 4 | |
NCT01540734 | GlaxoSmithKline |
Healthy Subjects
|
December 2009 | Phase 1 |
NCT04662567 | Northwell Health |
Postoperative Pain|IVF
|
March 12, 2021 | Not Applicable |
NCT04640376 | Unither Pharmaceuticals, France|AIXIAL Development |
Acute Pain
|
March 24, 2021 | Phase 3 |
NCT04202224 | Lithuanian University of Health Sciences |
Pre-emptive Analgesia in Different Psycho-emotional Status Patients
|
October 1, 2018 | Not Applicable |
NCT00029770 | National Center for Complementary and Integrative Health (NCCIH) |
Neck Pain
|
September 2001 | Phase 2 |
NCT03084536 | Washington University School of Medicine |
Breast Cancer|Breast Cancer Female|Cancer of Breast
|
June 7, 2017 | Phase 2 |
NCT00681174 | University of Parma |
Anesthesia Recovery Period|Pain, Postoperative
|
July 2008 | Phase 4 |
NCT01420666 | AFT Pharmaceuticals, Ltd. |
Osteoarthritis
|
Phase 3 | |
NCT01737593 | University of California, Los Angeles |
Emergence Agitation|Pain
|
November 2012 | Phase 4 |
NCT02678416 | Mallinckrodt |
Pain
|
December 7, 2015 | Phase 4 |
NCT00371696 | University of Bristol |
Osteoarthritis
|
December 2001 | Phase 2 |
NCT04459117 | Institut National de la Santé Et de la Recherche Médicale, France|UPCET|PARTNERS for International clinical Research|European Fundation for the Care of the Newborn Infants|Connect for Children |
Patency of the Ductus Arteriosus|Acetaminophen|Extreme Prematurity
|
October 29, 2020 | Phase 2|Phase 3 |
NCT03622489 | Wolfson Medical Center |
Postoperative Pain|Post-Cesarean Section
|
March 1, 2017 | Phase 4 |
NCT00489424 | Novartis Pharmaceuticals|Novartis |
Osteoporosis
|
June 2007 | Phase 4 |
NCT02241148 | Universidad Autonoma de Nuevo Leon |
Patellofemoral Pain Syndrome
|
February 2014 | Not Applicable |
NCT02229786 | Boehringer Ingelheim |
Gastrointestinal Diseases
|
February 1998 | Phase 2 |
NCT03570541 | Zealand University Hospital |
Postoperative Pain
|
June 28, 2018 | Phase 4 |
NCT03081728 | Postgraduate Institute of Medical Education and Research |
Respiratory Insufficiency
|
April 1, 2017 | Not Applicable |
NCT03472469 | The University of Texas Health Science Center, Houston|National Center for Advancing Translational Sciences (NCATS) |
Nonspecific Pain Post Traumatic Injury
|
April 2, 2018 | Phase 4 |
NCT03947671 | Virginia Commonwealth University|Stryker Medical |
Cardiac Surgery|Post-operative Cognitive Dysfunction|Fever
|
January 22, 2020 | Phase 2 |
NCT01607905 | Karyopharm Therapeutics Inc |
Solid Tumor
|
June 18, 2012 | Phase 1 |
NCT03391284 | Scripps Health |
Post-operative Pain
|
February 2016 | Not Applicable |
NCT00619203 | Kamuzu University of Health Sciences |
Bacterial Meningitis
|
March 2008 | Phase 3 |
NCT04673214 | Gilberto Cruz Arteaga|Coordinación de Investigación en Salud, Mexico |
Covid19
|
December 16, 2020 | Phase 3 |
NCT00970450 | University Hospital, Basel, Switzerland |
Analgesia
|
November 2009 | Not Applicable |
NCT01562704 | University Hospital, Clermont-Ferrand|Dr. Gisèle PICKERING (MCU, PH)|Dr. Betty JEAN (PH) |
Pain
|
January 2012 | Phase 1 |
NCT05564819 | Nanjing Children´s Hospital |
Analgesic|Enhanced Recovery After Surgery|Postoperative Pain|Infant ALL|Acetaminophen
|
September 14, 2022 | Phase 1 |
NCT03732469 | University of South Florida |
Opioid Use
|
November 1, 2019 | Phase 4 |
NCT03635684 | Saint-Joseph University |
Pain|Fever|Drug Effect|Drug Reaction
|
May 17, 2018 | Phase 2 |
NCT01381120 | Barrie Urology Associates|Astellas Pharma Canada, Inc. |
Flank Pain|Urinary Bladder, Overactive
|
October 2010 | Phase 4 |
NCT02498483 | Columbia University |
Pain|Circumcision
|
September 2015 | Phase 4 |
NCT00000731 | National Institute of Allergy and Infectious Diseases (NIAID) |
HIV Infections
|
Not Applicable | |
NCT00240838 | Johnson & Johnson Consumer and Personal Products Worldwide |
Pain
|
May 2003 | Phase 4 |
NCT03088826 | Antonios Likourezos|Maimonides Medical Center |
Pain Management
|
August 18, 2017 | Phase 2 |
NCT05499234 | Medipol University |
Labor Pain
|
August 1, 2022 | Phase 1 |
NCT02418182 | University of Alabama at Birmingham |
Pain
|
January 2015 | Phase 4 |
NCT01318187 | Pamukkale University |
Urolithiasis
|
January 2011 | Phase 4 |
NCT05544734 | Weill Medical College of Cornell University |
Nail Diseases|Nail Abnormality
|
November 2022 | Phase 4 |
NCT01837394 | Jens Borglum Neimann|Bispebjerg Hospital |
Postoperative Pain|Postoperative Nausea and Vomiting|Postoperative Function Level
|
August 2012 | Phase 4 |
NCT01960114 | McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.|Johnson & Johnson Consumer and Personal Products Worldwide |
Dental Pain
|
October 2013 | Phase 2 |
NCT04690673 | Johanna Kujala|Helsinki University Central Hospital |
Drug Mechanism|Healthy
|
January 15, 2021 | Not Applicable |
NCT04221477 | Hoffmann-La Roche |
Lupus Nephritis
|
August 10, 2020 | Phase 3 |
NCT02305017 | Bial - Portela C S.A. |
Parkinson´s Disease
|
March 2014 | Phase 1 |
NCT03068260 | Zealand University Hospital |
Postoperative Pain
|
March 15, 2017 | Phase 4 |
NCT02205489 | Genzyme, a Sanofi Company|Sanofi |
Relapsing-remitting Multiple Sclerosis
|
October 2014 | Phase 4 |
NCT02641899 | Intarcia Therapeutics |
Healthy
|
December 2015 | Phase 1 |
NCT01228305 | Vanderbilt University Medical Center |
Congenital Heart Disease|Cardiopulmonary Bypass
|
July 2011 | Not Applicable |
NCT02698995 | Foisor Orthopedics Clinical Hospital |
Postoperative Pain
|
November 2015 | Phase 3 |
NCT01544062 | University of Washington|Mallinckrodt |
Acute Pain|Hyperalgesia
|
July 2012 | Phase 4 |
NCT00750347 | University Hospital, Clermont-Ferrand |
Pain
|
September 2008 | Phase 1 |
NCT05354479 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
Pain Control
|
October 20, 2021 | Phase 4 |
NCT00236483 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C.|PriCara, Unit of Ortho-McNeil, Inc. |
Surgery, Oral|Pain, Postoperative
|
November 2002 | Phase 4 |
NCT02570581 | Centre Hospitalier Universitaire de Nice |
Healthy
|
June 2014 | Phase 1 |
NCT04976387 | Loma Linda University |
Postoperative Pain|Patient Satisfaction|Analgesia
|
July 2, 2021 | Phase 3 |
NCT01605903 | Massachusetts Eye and Ear Infirmary|United States Naval Medical Center, San Diego|Brooke Army Medical Center|United States Naval Medical Center, Portsmouth|Madigan Army Medical Center |
Tonsillectomy|Adenoidectomy
|
May 3, 2012 | Phase 2 |
NCT01120769 | Vanderbilt University |
Acute Myocardial Infarction
|
July 2011 | Not Applicable |
NCT03734627 | St. James´s Hospital, Ireland |
Esophageal Cancer|Nutrition Disorders|Appetite Disorders|Dumping Syndrome|Delayed Gastric Emptying|Surgery
|
July 1, 2016 | |
NCT02602197 | Baskent University |
Postoperative Pain
|
August 2013 | Phase 3 |
NCT02244619 | Kettering Health Network |
Post-op Pain
|
September 2014 | Phase 4 |
NCT03437707 | Inonu University |
Postoperative Pain Management
|
February 13, 2018 | Not Applicable |
NCT04986839 | Manchester University NHS Foundation Trust |
Patent Ductus Arteriosus
|
September 3, 2021 | Phase 2|Phase 3 |
NCT03695367 | Heron Therapeutics |
Postoperative Pain
|
October 1, 2018 | Phase 2 |
NCT03062488 | Nemours Children´s Clinic|University of Central Florida |
Emergence Agitation|Pain
|
October 3, 2017 | Early Phase 1 |
NCT02605187 | Stanford University |
Postoperative Pain
|
November 2015 | Not Applicable |
NCT04495283 | Nevakar, Inc.|Nevakar Injectables, Inc. |
Postoperative Pain
|
July 28, 2020 | Phase 2 |
NCT01392378 | Pfizer |
Pneumococcal Vaccines
|
August 2011 | Phase 4 |
NCT03953287 | Kolding Sygehus |
Pharmacological Action
|
August 18, 2019 | Phase 1 |
NCT02179892 | Colette Curtis MD|Emory University |
Pain
|
July 2014 | Phase 4 |
NCT01291654 | Shaare Zedek Medical Center |
Patent Ductus Arteriosus
|
April 2012 | Phase 2 |
NCT01891435 | Hamad Medical Corporation |
Fever|Reduction in Temperature
|
January 2010 | Not Applicable |
NCT02749162 | Foisor Orthopedics Clinical Hospital |
Postoperative Pain
|
November 2015 | Phase 3 |
NCT01652183 | Pinar Ergenoglu|Baskent University |
Catheter Related Bladder Discomfort
|
October 2008 | Phase 4 |
NCT01869699 | University of California, San Francisco |
Fever|Critical Illness
|
September 2013 | Phase 4 |
NCT02700451 | Hospital for Special Surgery, New York |
Lumbar Osteoarthritis|Spondylosis|Lumbar Disc Disease|Spinal Stenosis
|
March 2016 | Not Applicable |
NCT00493311 | Mallinckrodt |
Fever
|
June 2007 | Phase 3 |
NCT05253014 | Bahaa Mohammed Refaie|Sohag University |
Post-Dural Puncture Headache
|
January 1, 2018 | Not Applicable |
NCT03224403 | Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division|Johnson & Johnson Consumer and Personal Products Worldwide |
Post-operative Dental Pain
|
July 19, 2017 | Phase 3 |
NCT02719834 | University of Florida|Florida Department of Health |
Alzheimer´s Disease
|
April 2016 | |
NCT01822665 | GlaxoSmithKline |
Gastrointestinal Mucosal Damage
|
February 2012 | Phase 4 |
NCT03161509 | Rambam Health Care Campus |
Bariatric Surgery Candidate
|
July 1, 2017 | Phase 4 |
NCT01048398 | Basque Health Service |
Breech Presentation|Pregnancy
|
June 2010 | Phase 3 |
NCT01520792 | University Hospital, Clermont-Ferrand |
Healthy
|
November 2011 | Phase 1 |
NCT02884921 | Bnai Zion Medical Center |
Adverse Anesthesia Outcome
|
April 2015 | Not Applicable |
NCT00982215 | University Hospital, Clermont-Ferrand|Unither Pharmaceuticals |
Healthy
|
September 2009 | Phase 1 |
NCT01428375 | Ain Shams University |
Labor Pain
|
August 2011 | Phase 3 |
NCT02691572 | Mansoura University |
Postcesarean Analgesia
|
February 2016 | Not Applicable |
NCT05597878 | Wake Forest University Health Sciences |
Pain Management|Opioid Use|Prostate Cancer
|
January 2023 | Phase 2|Phase 3 |
NCT00246168 | Janssen Korea, Ltd., Korea |
Arthritis, Rheumatoid
|
Phase 4 | |
NCT00298974 | Abbott |
Osteoarthritis
|
February 2006 | Phase 3 |
NCT02544282 | GZA Ziekenhuizen Campus Sint-Augustinus |
Pain, Postoperative|Postoperative Nausea and Vomiting
|
April 2014 | Phase 4 |
NCT01523080 | Ranbaxy Laboratories Limited|Ranbaxy Inc. |
Healthy
|
May 2006 | Not Applicable |
NCT00484744 | University of Missouri, Kansas City |
Orthodontic Pain
|
June 2007 | Phase 4 |
NCT02524743 | Suleyman Demirel University |
Injection Site Irritation
|
May 2014 | Phase 4 |
NCT03131713 | Tufts Medical Center |
Non-melanoma Skin Cancer
|
July 1, 2016 | Phase 3 |
NCT01739699 | NorthShore University HealthSystem|Cadence Pharmaceuticals |
Craniotomy|Brain Surgery
|
January 2012 | Phase 4 |
NCT03558555 | Yan Lai|Icahn School of Medicine at Mount Sinai |
Inguinal Hernia
|
December 8, 2017 | Phase 4 |
NCT03375593 | Lawson Health Research Institute|Canadian Institutes of Health Research (CIHR) |
Distal Radius Fracture|Pain Management|Metacarpal Fracture
|
August 1, 2019 | Phase 4 |
NCT01328782 | University of Colorado, Denver |
Elbow Fracture
|
June 2008 | Not Applicable |
NCT00300924 | Diamond Headache Clinic|Merck Sharp & Dohme LLC |
Migraine
|
March 2006 | Phase 3 |
NCT00152854 | University Health Network, Toronto |
Cancer|Pain
|
July 2005 | Phase 3 |
NCT03829774 | DyAnsys, Inc. |
Cesarean Section; Dehiscence
|
January 2, 2019 | Not Applicable |
NCT02703259 | Christiana Care Health Services |
Pain, Postoperative
|
June 2016 | Phase 4 |
NCT03538457 | Norwegian University of Science and Technology|St. Olavs Hospital|Volvat Medisinsk Senter Stokkan|Namsos Hospital|Alesund Hospital |
Obesity, Morbid
|
November 2, 2016 | |
NCT03126084 | Bozyaka Training and Research Hospital |
Inguinal Hernia|Postoperative Pain
|
May 2, 2017 | Phase 4 |
NCT00925951 | Korea Institute of Oriental Medicine |
Low Back Pain
|
June 2009 | Not Applicable |
NCT04629248 | Hoffmann-La Roche |
Primary Membranous Nephropathy
|
June 25, 2021 | Phase 3 |
NCT01598701 | The University of Texas Health Science Center, Houston|Mallinckrodt |
Postoperative Pain
|
May 2, 2012 | Phase 4 |
NCT02987985 | University of Saskatchewan |
Anesthesia|General Anesthesia|Analgesics, Opioid|Postoperative Complications|Pathologic Processes|Physiologic Effects of Drugs|Narcotics|Analgesics|Sleep Disordered Breathing|Obstructive Sleep Apnea of Child|Tonsillectomy|Respiratory Depression|Dexmedetomidine|Ketamine|Lidocaine|Gabapentin|Pulse Oximetry
|
October 15, 2017 | Phase 3 |
NCT02292667 | Centre Hospitalier Universitaire de Besancon |
Aortic Aneurysm, Abdominal|Pain|Anesthesia, Local
|
January 2015 | Phase 3 |
NCT02549716 | Milton S. Hershey Medical Center |
Subarachnoid Hemorrhage|Stroke
|
January 5, 2017 | Phase 4 |
NCT02815111 | University of Florida |
Pain
|
July 2016 | |
NCT00635349 | Janssen Korea, Ltd., Korea |
Osteoarthritis
|
May 2007 | Phase 4 |
NCT02648490 | Henlix, Inc |
Solid Tumour
|
September 2016 | Phase 1 |
NCT01588158 | Massachusetts General Hospital |
Carpal Tunnel Syndrome
|
July 2012 | Phase 4 |
NCT01586143 | University Hospital, Clermont-Ferrand |
Acute Pain
|
May 2012 | Phase 3 |
NCT05396677 | University of Guelph|Natural Sciences and Engineering Research Council, Canada |
Fear
|
May 2022 | Not Applicable |
NCT01979510 | Merck Sharp & Dohme LLC |
Low Back Pain
|
November 2013 | Phase 3 |
NCT02400580 | University of Pittsburgh |
Pain
|
February 2015 | Phase 4 |
NCT02288923 | Royal Devon and Exeter NHS Foundation Trust |
Arthritis Knee
|
March 2015 | Not Applicable |
NCT00921700 | Ullevaal University Hospital|University of Oslo|Oslo University Hospital |
Pain, Postoperative
|
June 2009 | Phase 4 |
NCT05428306 | Laboratorios Silanes S.A. de C.V. |
Healthy
|
October 23, 2018 | Phase 1 |
NCT02804633 | Jewish Hospital, Cincinnati, Ohio |
Pain Control Post Colorectal Surgery
|
August 2013 | Not Applicable |
NCT02369133 | Baskent University |
Cesarean Section; Dehiscence
|
November 2013 | Phase 4 |
NCT02174068 | University Hospital, Clermont-Ferrand |
Healthy Volunteers
|
July 2014 | Phase 1 |
NCT02375100 | Bozyaka Training and Research Hospital |
Pain, Postoperative
|
February 2015 | Not Applicable |
NCT02113566 | Jean Brown Research |
Delayed Onset Muscle Soreness
|
February 2013 | Phase 4 |
NCT03860428 | Lviv National Medical University |
Patent Ductus Arteriosus
|
February 15, 2019 | Not Applicable |
NCT03649165 | AstraZeneca |
Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)|Healthy Participants
|
September 5, 2018 | Phase 1 |
NCT01116596 | University Hospital, Clermont-Ferrand |
Chronic Pain|Elderly
|
February 2007 | Phase 1 |
NCT02902172 | St. Louis University |
Hypertension
|
March 15, 2017 | Phase 4 |
NCT05425355 | University Health Network, Toronto |
Hip-fracture|Surgery
|
November 4, 2022 | Phase 4 |
NCT02785549 | Corporacion Parc Tauli |
Acute Diverticulitis
|
November 2016 | Phase 4 |
NCT03844776 | Taibah University |
Infection
|
October 2, 2019 | Not Applicable |
NCT02255955 | Diskapi Yildirim Beyazit Education and Research Hospital |
Postoperative Pain|Postoperative Laminectomy Pain
|
October 2014 | Phase 4 |
NCT02556970 | University Hospitals Bristol and Weston NHS Foundation Trust|David Telling Charitable Trust |
Pain, Postoperative
|
Not Applicable | |
NCT01410409 | Northern Orthopaedic Division, Denmark|The Danish Rheumatism Association|Obel Family Foundation|Spar Nord Foundation|The Bevica Foundation|Aalborg University|Association of Danish Physiotherapists|Formthotics|Medical Specialist Heinrich Kopp´s Grant|Danish Medical Association |
Osteoarthritis of the Knee
|
September 2011 | Not Applicable |
NCT01635101 | Mallinckrodt |
Acute Pain
|
June 2012 | Phase 3 |
NCT02443142 | Northwestern University|Northwestern Memorial Hospital |
Brain Concussion
|
May 1, 2015 | Phase 2 |
NCT02402543 | University of Vermont|American Society of Colon and Rectal Surgeons |
Hemorrhoids|Fissure in Ano|Rectal Fistula|Anal Condyloma
|
June 2014 | Not Applicable |
NCT00390260 | Merck Sharp & Dohme LLC |
Pain, Postoperative Arthroscopy
|
February 2002 | Phase 3 |
NCT03475693 | Spectrum Health - Lakeland|Michigan State University |
Concussion Post Syndrome
|
September 1, 2017 | Early Phase 1 |
NCT02662660 | Hospital General Universitario Elche |
Postoperative Pain
|
January 2012 | Phase 3 |
NCT03781505 | Aga Khan University |
Postoperative Analgesia
|
January 31, 2019 | Phase 4 |
NCT00137969 | Genentech, Inc. |
Lupus Erythematosus, Systemic
|
May 10, 2005 | Phase 2|Phase 3 |
NCT04622813 | American University of Beirut Medical Center |
Cholecystectomy|Pain, Postoperative|Opioid Use
|
April 8, 2021 | Phase 3 |
NCT03073980 | Massachusetts General Hospital |
Infertility, Female|Pain, Postoperative
|
September 1, 2019 | Phase 4 |
NCT00240825 | Johnson & Johnson Consumer and Personal Products Worldwide|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Pain
|
Phase 4 | |
NCT03843281 | Bruno Minotti|Cantonal Hospital of St. Gallen |
Analgesia
|
May 2, 2019 | Phase 4 |
NCT02452320 | Weill Medical College of Cornell University |
Obesity
|
February 2016 | Phase 4 |
NCT05248152 | University Medical Centre Ljubljana |
Postoperative Pain
|
January 13, 2022 | Not Applicable |
NCT00434681 | Sanofi |
Fever|Pain
|
October 2006 | Phase 3 |
NCT04381104 | Dow University of Health Sciences |
Anxiety|Pain|Discomfort
|
November 21, 2019 | Not Applicable |
NCT01432977 | University Hospital, Limoges |
Pain
|
September 2011 | Phase 3 |
NCT03586934 | Rush University Medical Center |
Shoulder Pain|Opioid Use
|
June 1, 2018 | Phase 3 |
NCT01760330 | Nationwide Children´s Hospital |
Cleft Palate
|
December 2015 | Phase 2 |
NCT03041935 | Alberta Children´s Hospital |
Testicle Undescended|Pain, Postoperative
|
September 1, 2015 | Not Applicable |
NCT05340582 | Mount Sinai Hospital, Canada|Sunnybrook Health Sciences Centre|McMaster Children´s Hospital|The Rotunda Hospital |
Patent Ductus Arteriosus After Premature Birth
|
November 2022 | Phase 2 |
NCT00743093 | Denver Health and Hospital Authority|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Drug Toxicity|Healthy
|
August 2008 | Phase 4 |
NCT02206178 | University Hospital, Clermont-Ferrand |
Healthy
|
September 2013 | Phase 1 |
NCT01298778 | Wake Forest University Health Sciences |
Other Chronic Postoperative Pain
|
August 2010 | Not Applicable |
NCT00525967 | Faculdade de Medicina do ABC |
Cancer|Pain|Palliative Care
|
February 2006 | Phase 2|Phase 3 |
NCT04414995 | Indonesia University |
Analgesia
|
June 5, 2020 | Phase 2|Phase 3 |
NCT02056223 | University of Padova |
Ductus Arteriosus Patent|Respiratory Distress Syndrome
|
January 9, 2017 | Phase 2|Phase 3 |
NCT02366065 | Johns Hopkins University |
Glaucoma
|
January 2015 | Early Phase 1 |
NCT04874675 | University of Zimbabwe|UZ-CHS-PERFECT |
Impacted Third Molar Tooth|PAIN
|
June 2021 | Not Applicable |
NCT02028715 | Aultman Health Foundation |
Post-operative Pain
|
December 24, 2013 | Phase 4 |
NCT05097950 | Western Galilee Hospital-Nahariya |
Labor Pain
|
November 2021 | Not Applicable |
NCT03617900 | Thammasat University |
Postpartum Disorder
|
August 29, 2018 | Phase 1|Phase 2 |
NCT01721486 | Kaveh Aslani, MD|William Beaumont Hospitals |
Tonsillitis|Airway Obstruction|Difficulty Swallowing
|
September 2012 | Phase 4 |
NCT02155738 | Halina M Zyczynski, MD|University of Pittsburgh |
Pelvic Organ Prolapse
|
July 2014 | Phase 4 |
NCT03297073 | University Hospital, Lille |
Paracetamol Causing Adverse Effects in Therapeutic Use|Hepatic Disease
|
December 20, 2016 | Not Applicable |
NCT05413902 | University of Puerto Rico |
Pain Management|Posterior Spinal Fusion
|
April 5, 2021 | Phase 4 |
NCT03568721 | Rio de Janeiro State University|Conselho Nacional de Desenvolvimento Científico e Tecnológico |
Pain
|
January 25, 2015 | Phase 4 |
NCT02002741 | Rambam Health Care Campus |
Ductus Arteriosus, Patent
|
August 1, 2014 | Phase 2|Phase 3 |
NCT02836509 | Pamukkale University |
Low Back Pain
|
September 2016 | Phase 4 |
NCT04408560 | Institut Jean-Godinot |
Breast Cancer Female|Joint Pain
|
September 13, 2018 | Not Applicable |
NCT05547659 | October 6 University|Beni-Suef University |
Compare Unimodal and Multimodal Analgesics
|
January 1, 2019 | Phase 1|Phase 2 |
NCT01462370 | Organon and Co |
Dysmenorrhea
|
November 2011 | Phase 3 |
NCT00078559 | University of Wisconsin, Madison|Immune Tolerance Network (ITN) |
Kidney Transplantation|Kidney Disease
|
November 2003 | Phase 1|Phase 2 |
NCT00411190 | GlaxoSmithKline |
Osteoarthritis
|
October 19, 2006 | Phase 1 |
NCT00427206 | Denver Health and Hospital Authority|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Alcohol Related Disorders
|
November 2004 | Phase 4 |
NCT02262702 | GlaxoSmithKline |
Osteoarthritis
|
January 2013 | |
NCT02401529 | King Fahd General Hospital |
Postoperative Pain|Postoperative Nausea and Vomiting
|
January 2013 | Phase 2 |
NCT04372264 | Pamukkale University |
Headache, Migraine
|
October 15, 2018 | Phase 4 |
NCT02043704 | TriHealth Inc. |
Post Operative Pain
|
January 2014 | Phase 4 |
NCT03754686 | Rambam Health Care Campus |
Influenza
|
February 10, 2019 | Phase 4 |
NCT02763059 | King Abdulaziz University |
Pain Measurement
|
September 2013 | Phase 4 |
NCT04038307 | Cairo University |
Cesarean Section
|
August 1, 2019 | Phase 2|Phase 3 |
NCT03858231 | Sanford Health |
Knee Injuries|Pain, Postoperative|Opioid Use
|
October 29, 2018 | Phase 4 |
NCT00400621 | Denver Health and Hospital Authority|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Moderate Alcohol Consumption (1-3 Drinks Per Day)
|
April 2003 | Phase 4 |
NCT01827475 | Stony Brook University |
Pain
|
July 2010 | Phase 2 |
NCT04767178 | Istanbul Medeniyet University |
Retinopathy of Prematurity|Pain Management
|
January 1, 2020 | |
NCT02474199 | National Institute of Allergy and Infectious Diseases (NIAID)|Clinical Trials in Organ Transplantation in Children|Rho Federal Systems Division, Inc. |
Liver Transplant Recipient|Living Donor (of the Respective Liver Transplant Recipient)
|
June 6, 2016 | Phase 1|Phase 2 |
NCT00763997 | Ruhr University of Bochum|Pfizer |
Platelet Aggregation
|
February 2004 | Not Applicable |
NCT00003346 | Memorial Sloan Kettering Cancer Center|National Cancer Institute (NCI) |
Melanoma (Skin)
|
November 1997 | Phase 2 |
NCT03849625 | Chulalongkorn University |
Aspirin Sensitivity|Aspirin-exacerbated Respiratory Disease|Aspirin-Induced Angioedema-Urticaria|Aspirin Allergy|NSAID-Induced Asthma|NSAID-Induced Angioedema-Urticaria|NSAID-Induced Anaphylactoid Reaction|Aspirin-Induced Anaphylactoid Reaction
|
May 1, 2015 | |
NCT04015557 | Hospital de Clinicas de Porto Alegre|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil |
CBS Deficiency
|
February 11, 2022 | Phase 1|Phase 2 |
NCT01882530 | Rennes University Hospital |
Post Operative Analgesia
|
July 23, 2013 | Phase 4 |
NCT03241030 | University of Texas at Austin |
Herpangina|Gingivostomatitis|Hand, Foot and Mouth Disease
|
September 12, 2017 | Phase 2 |
NCT01587274 | Montefiore Medical Center |
Acute Low Back Pain
|
April 2012 | Phase 4 |
NCT04779255 | Poitiers University Hospital |
Pain|Actinic Keratosis|Analgesia|Phototerapy|Vertex
|
July 28, 2021 | Not Applicable |
NCT02958566 | University of Illinois College of Medicine at Peoria |
Colon Cancer|Colon Diverticulosis|Colonic Neoplasms|Colonic Diverticulitis|Pain, Postoperative|Ileus|Ileus Paralytic|Ileus; Mechanical|Constipation Drug Induced|Constipation|Rectum Cancer|Rectum Neoplasm
|
January 2017 | Phase 4 |
NCT04123873 | Naestved Hospital |
Pain, Acute|Hip Arthropathy|Analgesia|Postoperative Pain
|
March 5, 2020 | Phase 4 |
NCT01104844 | AFT Pharmaceuticals, Ltd. |
Dental Pain
|
Phase 2 | |
NCT03428230 | Sintetica SA|Cross Research S.A. |
Pain, Postoperative
|
August 6, 2018 | Phase 2 |
NCT01453400 | Bayer |
Pharyngitis
|
September 27, 2011 | Phase 3 |
NCT04251351 | University of British Columbia|Mahidol Oxford Tropical Medicine Research Unit|Kinshasa Medical Oxford Research Unit |
Severe Malaria|Malaria,Falciparum|Acute Kidney Injury|Paracetamol
|
December 13, 2021 | Phase 3 |
NCT02689063 | AFT Pharmaceuticals, Ltd. |
Post Operative Pain
|
October 26, 2016 | Phase 3 |
NCT04290208 | Main Line Health|Sharpe-Strumia Research Foundation |
Postoperative Pain|Cesarean Section|Acetaminophen
|
August 22, 2019 | Phase 4 |
NCT04291508 | Massachusetts General Hospital |
Acute Respiratory Distress Syndrome|Critical Illness|Respiratory Failure|Sepsis
|
October 13, 2021 | Phase 2 |
NCT04608669 | Saint George Hospital |
Safety Issues
|
July 1, 2019 | Phase 4 |
NCT03771755 | Indonesia University |
Lower Extremity Problem|Surgery|Postoperative Pain
|
July 1, 2017 | Not Applicable |
NCT03679013 | Inova Health Care Services |
Pain, Postoperative
|
April 19, 2019 | Phase 2 |
NCT05025228 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS |
Femur Fracture
|
June 1, 2019 | |
NCT01394718 | Children´s Hospital of Philadelphia |
Pain, Postoperative
|
July 2011 | Phase 3 |
NCT00267293 | Penn State University|Children Youth and Family Consortium |
Fever
|
January 2006 | Phase 4 |
NCT00940836 | Hospital de Clinicas de Porto Alegre |
Common Cold|Flu-like Syndrome
|
June 2009 | Phase 3 |
NCT00880828 | Taipei Medical University WanFang Hospital |
Cervical Radiculopathy|Radicular Pain|Acute Neck Pain|Cervicobrachial Pain
|
August 2010 | Not Applicable |
NCT01332578 | GlaxoSmithKline |
Influenza|Common Cold
|
May 2011 | Phase 4 |
NCT02025166 | Rambam Health Care Campus |
Pain
|
January 2014 | Not Applicable |
NCT05076110 | Mayo Clinic |
Hip Arthroscopy
|
April 7, 2022 | Phase 4 |
NCT03781544 | University of Zurich |
Osteoarthritis of Multiple Joints of Ankle or Foot|Healthy
|
January 1, 2019 | Phase 4 |
NCT03107481 | Montefiore Medical Center |
Pain, Acute
|
June 4, 2017 | Phase 4 |
NCT05109312 | Heron Therapeutics |
Analgesia
|
October 18, 2021 | Phase 4 |
NCT02839876 | Duke University |
Osteoarthritis|Acetaminophen|Arthroplasty, Hip Replacement
|
March 14, 2017 | Phase 4 |
NCT00564486 | Mallinckrodt |
Pain
|
November 2007 | Phase 3 |
NCT03783702 | Stanford University|Mayo Clinic|Vanderbilt University Medical Center|Albert Einstein College of Medicine|University of British Columbia|NorthShore University HealthSystem |
Sinusitis|Opioid Use|Opioid Abuse|Narcotic Use|Otolaryngologic Disease|Postoperative Pain|Pain
|
April 4, 2019 | Phase 4 |
NCT02954484 | National University Hospital, Singapore |
Pain, Postoperative
|
April 2015 | Phase 3 |
NCT00561288 | University of Toronto |
Emotional Pain
|
November 2007 | Not Applicable |
NCT02452450 | Reckitt Benckiser Healthcare (UK) Limited|Simbec Research |
Healthy Volunteer Study
|
January 2014 | Phase 1 |
NCT01420094 | Bayer |
Healthy Subjects
|
June 16, 2011 | Phase 3 |
NCT00482053 | Stanford University |
Lymphoma, B-cell|Lymphoma, Non-Hodgkin|Diffuse Large B-cell Lymphoma (DLBCL)|Malignant Lymphoma, Non-Hodgkin
|
October 2006 | Phase 2 |
NCT01842633 | GlaxoSmithKline |
Pain
|
April 1, 2013 | Phase 3 |
NCT00923910 | National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC) |
Leukemia, Acute Myelogenous (AML)|Leukemia, Acute Lymphocytic (ALL)|Leukemia, Chronic Myelogenous (CML)|Myelodysplastic Syndrome (MDS)|Non-Hodgkin´s Lymphoma (NHL)
|
February 22, 2008 | Phase 1|Phase 2 |
NCT02408705 | Medical University of Graz|Novo Nordisk A+S |
Type 1 Diabetes Mellitus
|
January 2015 | Phase 2 |
NCT02833584 | Phramongkutklao College of Medicine and Hospital |
Dengue|Transaminitis
|
September 2016 | Not Applicable |
NCT01711229 | Babiash, Kimberly H., M.D. |
Pain, Postoperative
|
December 2015 | Phase 4 |
NCT01576809 | Novartis|Novartis Consumer Health |
Upper Respiratory Infections
|
March 2012 | Phase 3 |
NCT00713440 | Glostrup University Hospital, Copenhagen |
Type 2 Diabetes Mellitus|Steroids
|
July 2008 | Not Applicable |
NCT02029599 | Maoxiang Group Jilin Pharmaceutical Co., Ltd. |
Rheumatoid Arthritis
|
March 2014 | Phase 2 |
NCT03978767 | Washington University School of Medicine |
Preeclampsia Severe|Preeclampsia Postpartum
|
June 10, 2019 | Phase 2 |
NCT01966172 | Rigshospitalet, Denmark |
Analgesia|Postoperative Pain
|
March 2007 | Phase 4 |
NCT03818932 | Henry Ford Health System |
Anterior Cruciate Ligament Injury
|
January 22, 2019 | Phase 2|Phase 3 |
NCT03105518 | Brigham and Women´s Hospital |
Oocyte Retrieval|Postoperative Pain
|
March 1, 2011 | Phase 4 |
NCT03111186 | University of Southern California |
Carpal Tunnel Syndrome|Dupuytren Contracture|Trigger Digit|Ganglion Cysts|De Quervain Disease
|
April 24, 2017 | Phase 2 |
NCT00292214 | Melbourne Health |
Laparoscopic Cholecystectomy
|
October 2005 | Phase 4 |
NCT02891174 | University of Michigan |
Hypertension, Pregnancy-Induced|Pre-eclampsia
|
December 1, 2016 | Phase 4 |
NCT02848729 | Mallinckrodt |
Pain
|
February 2016 | Phase 4 |
NCT04087317 | Rambam Health Care Campus |
Pain|Post Partum Depression|Opioid Use|Breast Feeding
|
September 1, 2019 | Not Applicable |
NCT03846102 | Zuyderland Medisch Centrum|Fresenius Kabi |
Humans|Anesthetics, Local|Morphine|Pain Management|Analgesia|Pain|Anesthesia, Local|Fascia|Emergency Medicine|Analgesia, Patient-Controlled|Ultrasonography|Femoral Fracture
|
January 28, 2019 | Phase 4 |
NCT02233400 | St. Luke´s Hospital and Health Network, Pennsylvania |
Hospital Costs|Length of Stay|Postoperative Pain Score|Patient Satisfaction
|
February 2013 | Phase 4 |
NCT01798316 | Northwell Health |
Postoperative Pain|Postoperative Nausea|Postoperative Vomiting
|
March 2013 | Phase 4 |
NCT01583660 | Beijing Army General Hospital |
Hip Fracture
|
January 2012 | |
NCT01112462 | McNeil AB|Johnson & Johnson Consumer and Personal Products Worldwide |
Respiratory Tract Infections
|
March 2010 | Phase 1 |
NCT01105936 | GlaxoSmithKline |
Osteoarthritis, Knee
|
September 1, 2010 | Phase 4 |
NCT04324606 | University of Oxford |
Coronavirus
|
April 23, 2020 | Phase 1|Phase 2 |
NCT03592485 | Medical University of Lublin|Division of Cardiovascular Surgery, St. Jadwiga Provincial Clinical Hospital, Rzeszów, Poland |
Postoperative Pain|Mitral Valve Disease
|
June 28, 2018 | Phase 4 |
NCT03965819 | LifeSeasons Inc.|KGK Science Inc. |
Healthy
|
May 30, 2019 | Not Applicable |
NCT00634543 | Janssen Korea, Ltd., Korea |
Diabetic Neuropathy
|
December 2006 | Phase 4 |
NCT01070732 | University of Athens |
Fever|Analgesia
|
January 2010 | Phase 4 |
NCT01997112 | University of Edinburgh|British Heart Foundation|National Health Service, United Kingdom |
Blood Pressure
|
January 2014 | Phase 4 |
NCT01938261 | University of Oulu |
Persistent Ductus Arteriosus|Complication of Prematurity|Pain or Discomfort in Intensive Care of Preterm Infants
|
August 2013 | Phase 2 |
NCT01605240 | University of Manitoba |
Fracture|Pain
|
July 2012 | Not Applicable |
NCT02252419 | Seoul National University Hospital |
Pharyngitis
|
October 2014 | Not Applicable |
NCT02385188 | University Medical Center Nijmegen|Leiden University Medical Center|University Medical Center Groningen|Erasmus Medical Center|The Netherlands Cancer Institute|UMC Utrecht|Catharina Ziekenhuis Eindhoven |
Paget Disease, Extramammary
|
May 2015 | Phase 3 |
NCT00240799 | Johnson & Johnson Consumer and Personal Products Worldwide|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Osteoarthritis
|
Phase 3 | |
NCT01685658 | Centre Hospitalier Universitaire de N?mes |
Renal Colic|Acute Renal Colic
|
September 2016 | Phase 4 |
NCT03012763 | University Medicine Greifswald |
Pharmacokinetics|Magnetic Resonance Imaging|Administration, Oral
|
April 2016 | Phase 1 |
NCT03994731 | Horizon Therapeutics Ireland DAC|Horizon Pharma Ireland, Ltd., Dublin Ireland |
Gout
|
June 13, 2019 | Phase 4 |
NCT04122443 | Montefiore Medical Center |
Musculoskeletal Pain
|
December 1, 2019 | Phase 4 |
NCT01821872 | Barts & The London NHS Trust |
Paracetamol
|
May 2011 | Phase 4 |
NCT01770236 | Gundersen Lutheran Medical Foundation |
Postoperative Pain|Medication Side Effects|Narcotic Requirement
|
January 2013 | Phase 4 |
NCT02737124 | NYU Langone Health |
Post Operative Pain
|
February 16, 2017 | Phase 3 |
NCT02761980 | Pfizer |
Fever
|
December 6, 2016 | Phase 3 |
NCT02164929 | Duke University |
Laparoscopic Colorectal Resection
|
December 2013 | Not Applicable |
NCT04268498 | University of Miami|Amgen|Janssen Pharmaceuticals |
Multiple Myeloma
|
February 11, 2020 | Phase 2 |
NCT02076321 | University of Missouri-Columbia |
Fractures
|
January 2014 | Phase 4 |
NCT00736853 | Janssen Pharmaceutical K.K. |
Pain
|
June 2008 | Phase 3 |
NCT04959591 | Asan Medical Center |
Scoliosis; Adolescence
|
June 1, 2021 | Phase 3 |
NCT01382940 | Hoffmann-La Roche |
Rheumatoid Arthritis
|
July 26, 2011 | Phase 4 |
NCT01608217 | Radboud University Medical Center|Health Valley, Netherlands |
Behavioural Disturbances|Pain|Dementia|Alzheimer´s Dementia|Vascular Dementia
|
June 2012 | Phase 2 |
NCT00921505 | Ullevaal University Hospital|University of Oslo|Oslo University Hospital |
Pain
|
May 2009 | Phase 4 |
NCT02180334 | Seoul National University Hospital|Daewoong Pharmaceutical Co. LTD. |
Diabetes Mellitus, Type 2
|
July 2014 | Phase 4 |
NCT01420653 | AFT Pharmaceuticals, Ltd. |
Dental Pain
|
April 2013 | Phase 3 |
NCT01077752 | Assistance Publique - Hôpitaux de Paris |
Pain, Postoperative
|
February 2010 | Phase 3 |
NCT05246644 | McGill University Health Centre+Research Institute of the McGill University Health Centre|McMaster University|Montreal Heart Institute|University of Manitoba |
Delirium
|
March 1, 2022 | Phase 3 |
NCT03859102 | James Cook University Hospital|Medela AG |
Cardiac Surgery|Coronary Artery Disease|Aortic Valve Disease|Mitral Valve Disease|Tricuspid Valve Disease|Aortic Root Dilatation
|
December 17, 2018 | Not Applicable |
NCT02625753 | University of Sao Paulo General Hospital |
Myopia
|
November 2014 | Phase 3 |
NCT03509740 | Cairo University|Algazeerah hospital |
Dysmenorrhea
|
April 25, 2018 | Phase 4 |
NCT03412474 | Assiut University |
Cleft Palate
|
January 14, 2018 | Phase 2 |
NCT01782885 | Hospital Universitario Dr. Jose E. Gonzalez |
Knee Osteoarthritis
|
May 2013 | Not Applicable |
NCT04741139 | Baylor College of Medicine |
Immune Thrombocytopenia
|
October 20, 2021 | Phase 1 |
NCT02067442 | Thomas Jefferson University |
Pain
|
August 2013 | Not Applicable |
NCT01586299 | Rabin Medical Center |
Pleuro-pneumonia
|
March 2012 | Not Applicable |
NCT02327923 | B.P. Koirala Institute of Health Sciences |
Gall Stone Disease
|
January 2015 | Phase 4 |
NCT00381810 | Genentech, Inc. |
Lupus Erythematosus, Systemic
|
June 22, 2006 | Phase 3 |
NCT00679614 | Lawson Health Research Institute |
Hip Arthroplasty|Knee Arthroplasty|Spinal Anesthesia
|
December 17, 2007 | Phase 3 |
NCT01381640 | GlaxoSmithKline |
Healthy Subjects
|
April 2010 | Phase 1 |
NCT02785003 | Medical College of Wisconsin |
Acute Pain|Pain, Postoperative|Colorectal Surgery
|
July 2016 | Phase 4 |
NCT02154464 | Soroka University Medical Center |
Obesity
|
June 2014 | Not Applicable |
NCT00750048 | University Hospital, Clermont-Ferrand |
Pain
|
September 2008 | Phase 1 |
NCT01552798 | Bayer |
Headache
|
March 12, 2012 | Phase 3 |
NCT00000425 | Stanford University|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
Osteoarthritis
|
July 1996 | Phase 3 |
NCT03485625 | Assiut University |
Postoperative Pain
|
March 21, 2018 | Phase 3 |
NCT05285813 | M.D. Anderson Cancer Center |
AML|MDS
|
May 6, 2022 | Phase 2 |
NCT00370318 | GlaxoSmithKline |
Infections, Rotavirus
|
September 2006 | Phase 3 |
NCT01267136 | Children´s Hospitals and Clinics of Minnesota |
Tonsillitis|Pain
|
January 2011 | Phase 4 |
NCT02912650 | Pfizer |
Post-surgical Pain Following Extraction of Molar Teeth
|
September 2015 | Phase 3 |
NCT03541980 | Newark Beth Israel Medical Center |
Sickle Cell Anemia Crisis
|
February 20, 2018 | Phase 4 |
NCT05229965 | University of Monastir |
Acute Pain Due to Trauma
|
August 1, 2021 | Phase 3 |
NCT01544972 | Zekai Tahir Burak Women´s Health Research and Education Hospital |
Patent Ductus Arteriosus
|
February 2012 | Phase 4 |
NCT03415555 | Medical University of Lublin|Medical University of Rzeszów |
Postoperative Pain|Mitral Valve Disease
|
January 22, 2018 | Phase 4 |
NCT03955211 | Heron Therapeutics |
Analgesia
|
June 24, 2019 | Phase 2 |
NCT04028596 | Rijnstate Hospital|University of Twente|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
Epilepsy|Depression|Postictal Delirium|Electroconvulsive Therapy
|
December 5, 2019 | Phase 2 |
NCT05406752 | Unither Pharmaceuticals, France|Raptim Research |
Acute Pain
|
July 22, 2022 | Phase 1 |
NCT03413371 | Medical University of Silesia|Silesian University of Medicine |
Vitreoretinal Surgeries|Postoperative Nausea and Vomiting|Postoperative Pain|Oculocardiac Reflex
|
April 26, 2018 | Not Applicable |
NCT03415243 | GlaxoSmithKline |
Common Cold
|
March 1, 2018 | Phase 1 |
NCT02194894 | University of Southern California |
Non-alcoholic Fatty Liver Disease (NAFLD)
|
June 2014 | Not Applicable |
NCT01764555 | St. Antonius Hospital |
Morbid Obesity
|
December 2012 | Phase 4 |
NCT02643394 | University of Texas Southwestern Medical Center |
Postoperative Pain
|
August 17, 2015 | Phase 4 |
NCT01730326 | Pamukkale University |
Acute Migraine
|
March 2012 | Phase 4 |
NCT05284409 | Ain Shams University |
Shivering
|
July 1, 2022 | Phase 4 |
NCT03289390 | Albany Medical College |
Patent Ductus Arteriosus
|
August 1, 2017 | |
NCT02840526 | Silesian University of Medicine |
Postoperative Pain
|
May 2013 | Not Applicable |
NCT01231191 | University of California, San Diego|Cadence Pharmaceuticals |
Postoperative Pain|Intraoperative and Postoperative Opioid Requirements
|
Phase 4 | |
NCT01592227 | GlaxoSmithKline |
Pain
|
December 2009 | Phase 1 |
NCT02358850 | University of Nebraska |
Pain, Postoperative|Postoperative Nausea and Vomiting|Postoperative Hemorrhage|Body Weight Changes
|
January 2016 | Phase 4 |
NCT04037514 | Máximo Vento Torres|Instituto de Investigacion Sanitaria La Fe|Spanish Clinical Research Network - SCReN |
Patent Ductus Arteriosus After Premature Birth
|
July 7, 2017 | Phase 3 |
NCT01500109 | Loma Linda University |
Cleft Palate
|
November 2011 | Not Applicable |
NCT03105830 | Western Galilee Hospital-Nahariya |
Labour
|
May 2017 | Not Applicable |
NCT01973205 | Novartis |
Acute Migraine
|
October 2013 | Phase 3 |
NCT03599089 | Concentric Analgesics |
Post-surgical Pain
|
July 9, 2018 | Phase 2 |
NCT01858402 | Baskent University |
Other Acute Postoperative Pain
|
December 2009 | Phase 2 |
NCT03221998 | Soroka University Medical Center |
Obesity, Morbid
|
July 2017 | Early Phase 1 |
NCT05122351 | Sohag University |
Analgesia in Patients With Open Inguinal Hernia Surgeries
|
October 1, 2021 | Early Phase 1 |
NCT02069184 | Montefiore Medical Center |
Post-operative Pain
|
November 2013 | Phase 4 |
NCT03103022 | University of Florida |
Patent Ductus Arteriosus|Neonate
|
June 12, 2017 | Phase 1 |
NCT04765787 | The Searle Company Limited Pakistan |
Musculoskeletal Disorder|Pain Management
|
November 25, 2020 | |
NCT04653506 | Tel-Aviv Sourasky Medical Center |
Pain
|
November 28, 2020 | Not Applicable |
NCT01526525 | G.Gennimatas General Hospital|Aristotle University Of Thessaloniki |
Pain, Postoperative
|
July 2009 | Phase 4 |
NCT02110719 | Hartford Hospital |
Narcotic Use|Pain|Constipation|Nausea
|
March 2014 | Phase 4 |
NCT03570554 | Bayer |
Osteoarthritis, Knee
|
June 29, 2018 | Phase 2 |
NCT01988298 | Complejo Hospitalario Dr. Arnulfo Arias Madrid |
Hypertension
|
October 2013 | Phase 2|Phase 3 |
NCT02252614 | Diskapi Yildirim Beyazit Education and Research Hospital |
Postoperative Pain, PCA Contramal Consumption
|
September 2014 | Phase 4 |
NCT04615702 | Zagazig University |
Acute Pancreatitis
|
May 15, 2017 | |
NCT01313247 | Haraldsplass Deaconess Hospital |
Advanced Cancer|Opioid Use, Unspecified
|
April 2011 | Phase 4 |
NCT02504996 | Akdeniz University|Pamukkale University|Antalya Training and Research Hospital|University of Gaziantep|Ataturk University |
Sciatica
|
January 2015 | Phase 4 |
NCT03435692 | Seattle Children´s Hospital|Seattle Children´s Research Institute Center for Clinical and Translational Research |
Hip Surgery|Post Operative Pain Control
|
July 15, 2011 | Not Applicable |
NCT05116293 | University of Washington |
Transgender Persons
|
May 1, 2021 | |
NCT04662125 | Zagazig University |
Analgesia
|
December 10, 2020 | Not Applicable |
NCT00389272 | Assaf-Harofeh Medical Center |
Fever
|
September 2005 | Not Applicable |
NCT02667730 | Canadian Department of National Defense |
Ligament Injury
|
June 2015 | Phase 4 |
NCT02487303 | Medical University of South Carolina |
Pain, Postoperative
|
March 17, 2015 | Not Applicable |
NCT02774148 | Spectrum Health Hospitals |
Hip Fracture
|
December 2016 | Phase 4 |
NCT00712712 | Institut Bergonié |
Metastatic Cancer|Pain|Unspecified Adult Solid Tumor, Protocol Specific
|
December 24, 2007 | Phase 2 |
NCT03823534 | St. Louis University |
Bone Metastases|Lymphoma|Multiple Myeloma|Opioid Use|Pain
|
February 20, 2019 | Phase 3 |
NCT00766675 | Johnson & Johnson Taiwan Ltd |
Pain|Fibromyalgia
|
October 2008 | Phase 4 |
NCT03644147 | Seoul National University Hospital |
Postoperative Pain|Gynecologic Disease
|
August 27, 2018 | Not Applicable |
NCT04271917 | University of Tennessee |
Pain, Acute
|
February 24, 2020 | Phase 3 |
NCT02839668 | Iuliu Hatieganu University of Medicine and Pharmacy|Prof. Dr. I. Chiricuta Institute of Oncology |
Breast Cancer
|
August 2016 | Phase 2 |
NCT05548582 | Johns Hopkins University |
Pain, Postoperative|Opioid Misuse|Opioid Use|Pain
|
December 2022 | Not Applicable |
NCT04918147 | National Institute of Allergy and Infectious Diseases (NIAID)|Autoimmunity Centers of Excellence|Bristol-Myers Squibb|Rho Federal Systems Division, Inc. |
IgG4 Related Disease|IgG4-RD
|
October 13, 2021 | Phase 2 |
NCT02112448 | Advocate Health Care |
Congenital Heart Disease
|
June 2014 | Not Applicable |
NCT00314340 | University of California, Davis |
Chronic Pain
|
November 2005 | Phase 4 |
NCT03537144 | University of Tennessee |
Patent Ductus Arteriosus
|
June 2016 | Phase 3 |
NCT03651804 | University of California, Davis |
Vertebral Compression Fracture|Facet Joint Pain
|
April 10, 2019 | Phase 4 |
NCT01691690 | Nationwide Children´s Hospital |
Adenotonsillitis|Tonsillitis
|
October 2012 | Phase 2 |
NCT02987920 | University of Southern California |
Pain, Postoperative
|
January 2017 | Phase 4 |
NCT02911701 | University of New Mexico |
Pre-Eclampsia|HELLP Syndrome|Eclampsia
|
September 2016 | Phase 4 |
NCT03008876 | Albany Medical College |
Patent Ductus Arteriosus
|
January 1, 2017 | Not Applicable |
NCT01021696 | University of Bergen|The Research Council of Norway |
Dementia|Pain|Agitation
|
November 2009 | Phase 2|Phase 3 |
NCT02238288 | Grupo de Estudos Multicentricos em Onco-Hematologia|Rio de Janeiro State Research Supporting Foundation (FAPERJ) |
Oral Hemorrhage
|
December 2013 | Phase 4 |
NCT03789318 | Concentric Analgesics |
Postsurgical Pain
|
December 3, 2018 | Phase 2 |
NCT00841841 | University Center of Araraquara|University of Sao Paulo |
Pain, Postoperative
|
March 2006 | Phase 2 |
NCT00402571 | Denver Health and Hospital Authority|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Alcohol Related Disorders
|
January 2002 | Phase 4 |
NCT00324038 | Napp Pharmaceuticals Limited |
Osteoarthritis
|
March 2006 | Phase 4 |
NCT01248468 | Novartis |
Pain, Migraine
|
November 2010 | Phase 4 |
NCT01579786 | University of Padova |
Post Operative Pain
|
May 2011 | Not Applicable |
NCT03783312 | Inonu University |
Postoperative Pain|Myalgia|Headache
|
December 20, 2018 | Not Applicable |
NCT01755702 | GlaxoSmithKline |
Headache, Tension-Type
|
July 2009 | Phase 2|Phase 3 |
NCT03768882 | Pamukkale University |
Sore Throat
|
December 1, 2017 | Phase 4 |
NCT01002573 | Cumberland Pharmaceuticals |
Fever
|
July 2010 | Phase 3 |
NCT02621619 | Montefiore Medical Center|National Institute on Aging (NIA) |
Acute Pain
|
March 2016 | Phase 4 |
NCT01953978 | Rigshospitalet, Denmark|Glostrup University Hospital, Copenhagen |
Pain
|
December 2012 | Phase 4 |
NCT01947205 | Gökhan Açmaz|Kayseri Education and Research Hospital |
Curettage|Analgesia|Paracervical Block|Paracetamol
|
November 2012 | Not Applicable |
NCT03198871 | Kathirvel Subramaniam|Mallinckrodt|University of Pittsburgh |
Abdominal Wall Hernia|Pancreatic Diseases|Bowel Disease|Gastric Disease
|
May 24, 2018 | Phase 4 |
NCT01082081 | GlaxoSmithKline |
Post-surgical Dental Pain
|
October 2009 | Phase 4 |
NCT00210561 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C.|PriCara, Unit of Ortho-McNeil, Inc. |
Back Pain|Low Back Pain
|
March 2005 | Phase 4 |
NCT00240773 | Johnson & Johnson Consumer and Personal Products Worldwide|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Osteoarthritis, Hip|Osteoarthritis, Knee
|
Phase 3 | |
NCT01366976 | Vanderbilt University |
Cardiopulmonary Bypass Induced Lipid Peroxidation
|
July 2011 | Not Applicable |
NCT01460667 | McLaren Regional Medical Center|Cadence Pharmaceuticals |
Morbid Obesity
|
October 2011 | Not Applicable |
NCT02647047 | Ospedale San Raffaele |
Secondary Malignant Neoplasm of Liver|Liver Diseases|Liver Neoplasms
|
January 2016 | Not Applicable |
NCT01739361 | Vanderbilt University|Vanderbilt University Medical Center |
Severe Sepsis
|
April 2013 | Phase 2 |
NCT02777320 | Pamukkale University |
Sciatica
|
March 2016 | Phase 4 |
NCT03880981 | University of California, Los Angeles |
Musculoskeletal Injury
|
August 1, 2019 | Not Applicable |
NCT04879823 | David Chi, MD|University of Pittsburgh |
Adenotonsillectomy|Analgesia|Surgery
|
August 5, 2021 | Phase 3 |
NCT02911961 | Denver Health and Hospital Authority|Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division|University of Colorado, Denver|Rocky Mountain Poison and Drug Center |
Acetaminophen Exposure
|
August 2021 | Phase 4 |
NCT02188719 | National Institute of Allergy and Infectious Diseases (NIAID)|Rho Federal Systems Division, Inc. |
Liver Transplantation
|
December 17, 2014 | Phase 1 |
NCT05442268 | Tanta University |
Modified Radical Mastectomy|Postoperative Analgesia
|
July 16, 2022 | Not Applicable |
NCT01540721 | GlaxoSmithKline |
Healthy Subjects
|
December 2009 | Phase 1 |
NCT03702023 | Ascension Genesys Hospital |
Post Electrophysiology Procedure Pain
|
February 8, 2019 | Phase 4 |
NCT05125796 | Adiyaman University Research Hospital |
Scorpion Stings
|
September 1, 2020 | Not Applicable |
NCT02973958 | Alberta Children´s Hospital |
Pain, Postoperative|Phimosis|Paraphimosis|Balanitis
|
February 1, 2017 | Phase 1 |
NCT03448536 | Bayer |
Dysmenorrhea
|
April 5, 2018 | Phase 4 |
NCT04573426 | Ohio State University |
Overweight|Obesity|Healthy Adults
|
November 15, 2019 | |
NCT01564680 | Imam Abdulrahman Bin Faisal University |
Postoperative Pain
|
March 2009 | Phase 4 |
NCT01985126 | Janssen Research & Development, LLC |
Multiple Myeloma
|
September 27, 2013 | Phase 2 |
NCT01277081 | GlaxoSmithKline |
Common Cold
|
October 2010 | Phase 2 |
NCT03122314 | Pamukkale University |
Musculoskeletal Pain
|
August 2015 | Phase 4 |
NCT03121963 | University of Alabama at Birmingham |
Pain Management
|
November 10, 2017 | Phase 4 |
NCT00299039 | Nova Scotia Health Authority |
Pain|Breast Diseases
|
May 2006 | Phase 3 |
NCT02689024 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)|ZonMw: The Netherlands Organisation for Health Research and Development |
Hip Fractures|Anesthesia
|
May 2016 | Phase 4 |
NCT03626753 | Centre de Maternité de Monastir |
Cesarean Section; Complications, Wound, Infection (Following Delivery)|Postoperative Pain|Spinal Anaesthesia During the Puerperium
|
January 1, 2015 | Phase 2|Phase 3 |
NCT02837614 | Sun Yat-sen University |
Impacted Third Molar Tooth
|
October 2015 | Early Phase 1 |
NCT00899847 | Stanford University |
Transplantation, Homologous|Transplantation, Autologous|Multiple Myeloma|Blood and Marrow Transplant (BMT)
|
May 2009 | Phase 2 |
NCT00598702 | Mallinckrodt |
Pain|Fever
|
January 2008 | Phase 3 |
NCT02304783 | University of Monastir |
Renal Colic
|
January 2014 | Phase 1|Phase 2 |
NCT04646967 | Alberta Children´s Hospital |
Pain, Postoperative|Phimosis|Paraphimosis|Balanitis
|
August 20, 2022 | Phase 2 |
NCT01783236 | Weill Medical College of Cornell University|Mallinckrodt |
Lung Tumor
|
June 2013 | Phase 4 |
NCT03879408 | Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division|Johnson & Johnson Consumer and Personal Products Worldwide |
Pain
|
May 28, 2019 | Phase 2 |
NCT01756209 | University of Catanzaro |
Migraine
|
January 2010 | Phase 4 |
NCT04682743 | Cairo University |
Post-Operative Shivering
|
January 6, 2021 | Early Phase 1 |
NCT00405158 | Karlstad University |
Mastitis
|
January 2002 | Not Applicable |
NCT00488540 | University Hospital, Basel, Switzerland|Neonatology and Obstetrics, University Hospital Inselspital Berne|University Hospital, Zürich |
Pain
|
June 2007 | Phase 4 |
NCT01448057 | Novartis |
Upper Respiratory Tract Infection|Nasal Congestion|Rhinorrhea|Sneezing
|
July 2013 | Phase 3 |
NCT03060265 | Bnai Zion Medical Center |
Analgesia
|
March 2017 | Not Applicable |
NCT02625454 | Richmond University Medical Center |
Fever|Oxidative Stress
|
December 2016 | Phase 2 |
NCT02311881 | GlaxoSmithKline |
Pain
|
January 2015 | Phase 3 |
NCT02914028 | Istanbul University |
Postoperative Pain
|
April 2016 | Not Applicable |
NCT04347720 | IWK Health Centre|Provincial Health Services Authority|Children´s Hospital of Eastern Ontario|CHU de Quebec-Universite Laval|Foothills Medical Centre|Victoria General Hospital|The Hospital for Sick Children|Health Sciences Centre, Winnipeg, Manitoba|St. Justine´s Hospital|Queen´s University|MOUNT SINAI HOSPITAL|Royal Alexandra Hospital|Regina General Hospital|Royal University Hospital Foundation|St. Boniface Hospital|The Moncton Hospital|Horizon Health Network|Sunnybrook Health Sciences Centre|Windsor Regional Hospital|Royal Columbian Hospital|Centre de recherche du Centre hospitalier universitaire de Sherbrooke|London Health Sciences Centre|Canadian Institutes of Health Research (CIHR) |
Patent Ductus Arteriosus|Extreme Prematurity
|
January 1, 2020 | |
NCT03830398 | Mustafa Kemal University |
Mental Disorders
|
November 20, 2018 | Phase 4 |
NCT00576173 | Johnson & Johnson Taiwan Ltd |
Pain
|
December 2005 | Phase 4 |
NCT04214691 | Janssen Korea, Ltd., Korea |
Healthy
|
December 17, 2019 | Phase 1 |
NCT04199572 | Hamad Medical Corporation |
Musculoskeletal Injury
|
September 1, 2022 | Phase 4 |
NCT04790812 | The University of Texas Health Science Center, Houston |
Pain, Postoperative
|
April 22, 2021 | Phase 4 |
NCT03549611 | Kevin J Flynn MD|University of Iowa |
Kidney Calculi|Pain, Postoperative
|
August 1, 2018 | Phase 4 |
NCT04968158 | Laboratorios Silanes S.A. de C.V. |
Acute Low Back Pain
|
November 29, 2021 | Phase 3 |
NCT04793490 | Ain Shams University |
Post-Dural Puncture Headache
|
March 15, 2021 | Not Applicable |
NCT00429624 | University of Colorado, Denver|Foundation for Chiropractic Education and Research (FCER) |
Neck Pain
|
September 1994 | Not Applicable |
NCT03087877 | DexCom, Inc. |
Diabetes Mellitus
|
February 3, 2017 | Not Applicable |
NCT01852955 | Northwestern University |
Pain
|
November 2013 | Not Applicable |
NCT00240864 | Johnson & Johnson Consumer and Personal Products Worldwide|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Pain
|
Phase 4 | |
NCT04882202 | Gangnam Severance Hospital |
Aortic Surgery
|
September 1, 2021 | Not Applicable |
NCT02425254 | University of Nottingham |
Pain|Surgical Wound
|
January 2016 | Phase 4 |
NCT02921906 | Royal Devon and Exeter NHS Foundation Trust |
Neonatal Diabetes
|
June 2016 | Not Applicable |
NCT04609254 | Pamukkale University |
Low Back Pain, Mechanical
|
December 15, 2018 | Phase 4 |
NCT00646906 | University of Pennsylvania |
Myocardial Infarction|Arthritis
|
June 2, 2004 | Not Applicable |
NCT00137059 | Queen´s University |
Hepatotoxicity
|
November 2002 | Not Applicable |
NCT00185692 | Stanford University |
Blood Cancer|Leukemia|Graft Versus Host Disease|Malignancy|CLL|NHL|Hodgkin´s Disease|MDS
|
August 2000 | Phase 2 |
NCT02546765 | Beth Israel Deaconess Medical Center |
Delirium
|
October 2015 | Phase 4 |
NCT01762891 | Hospital Universitario Pedro Ernesto |
Antiphospholipid Antibody Syndrome
|
March 2003 | Not Applicable |
NCT01948505 | University of Utah |
Post-operative Craniotomy Patients|Carotid Endarterectomy and Carotid Artery Stenosis Patients|Post-op Spine Patients Admitted to the NCCU|Endovascular Patients Undergoing Intracranial Intervention|Traumatic Brain Injuries NPO for at Least 12 Hours
|
August 2013 | Phase 4 |
NCT02251249 | University Hospital, Bordeaux |
Impairment of Gastric Emptying|Acute Phase of Myocardial Infarction
|
December 8, 2014 | Phase 4 |
NCT03469310 | Minerva A Romero Arenas|DHR Health Institute for Research and Development |
Thyroid Cancer|Thyroid Nodule|Thyroid Neoplasms|Thyroid Goitre|Thyroid Diseases|Parathyroid Diseases|Parathyroid Adenoma|Parathyroid Hyperplasia
|
March 9, 2018 | Phase 4 |
NCT02248493 | Lithuanian University of Health Sciences |
Pain, Postoperative|Recovery of Function|Child
|
November 2012 | Phase 4 |
NCT00377832 | Weill Medical College of Cornell University |
Fever|Heart Rate, Fetal (FHR)
|
July 2007 | Not Applicable |
NCT01540838 | University of Helsinki|Foundation for Paediatric Research, Finland |
Bacterial Meningitis
|
February 2012 | Phase 4 |
NCT05428293 | Laboratorios Silanes S.A. de C.V. |
Healthy
|
February 22, 2019 | Phase 1 |
NCT02514941 | University Medicine Greifswald |
Morbid Obesity
|
June 2007 | Phase 1 |
NCT02521415 | Wake Forest University Health Sciences|Carolinas Trauma Network Research Group|Charlotte, Houston, Milwaukee Prehospital Emergency Research Nodal Center-CHaMP-ERNC |
Bone Fracture
|
December 2015 | Phase 2 |
NCT02091297 | Dartmouth-Hitchcock Medical Center|Massachusetts General Hospital|Brigham and Women´s Hospital |
Caesarean Delivery
|
April 2014 | Not Applicable |
NCT01485198 | Hospital Universitario Dr. Jose E. Gonzalez |
Osteoarthritis, Knee
|
August 2011 | Phase 1 |
NCT03749616 | University of Missouri-Columbia |
Distal Radius Fracture
|
January 2, 2019 | Phase 4 |
NCT03759028 | University of California, Los Angeles |
Supracondylar Humerus Fracture
|
February 26, 2019 | Phase 4 |
NCT04176419 | Case Comprehensive Cancer Center |
Postoperative Pain Control|Opioid Consumption
|
January 17, 2020 | Phase 3 |
NCT05469204 | University of Washington |
Transgender Persons
|
October 2022 | |
NCT02018601 | Paula Diéguez García|Complexo Hospitalario Universitario de A Coruña |
no Reconstructive Breast Surgery
|
September 2013 | Phase 4 |
NCT02260934 | National Institute of Allergy and Infectious Diseases (NIAID)|Immune Tolerance Network (ITN) |
Lupus Nephritis
|
July 9, 2015 | Phase 2 |
NCT03585374 | Mundipharma Pharmaceuticals srl|Bioikos Ambiente Srl |
Acute Traumatic Pain
|
February 8, 2018 | Phase 3 |
NCT03323684 | Mansoura University |
Laparoscopic Cholecystectomy
|
October 1, 2017 | Not Applicable |
NCT03893175 | University of Pennsylvania |
Impacted Third Molar Tooth|Pain, Acute
|
May 10, 2019 | Phase 1 |
NCT03714919 | Arlyne Thung|Nationwide Children´s Hospital |
Adenoid Hypertrophy
|
August 2, 2019 | Phase 2 |
NCT05013437 | Ehsan Malek|Case Comprehensive Cancer Center |
Multiple Myeloma
|
December 2022 | Early Phase 1 |
NCT01608308 | The University of Texas Health Science Center, Houston|Mallinckrodt |
Chronic Sinusitis
|
July 2012 | Not Applicable |
NCT05051735 | Oslo University Hospital|Sykehuset Telemark |
Cancer Pain|Cancer
|
October 20, 2021 | Phase 3 |
NCT01790009 | University of Reading |
Healthy
|
February 2011 | Phase 1 |
NCT02583594 | Genzyme, a Sanofi Company|Sanofi |
Progressive Multiple Sclerosis
|
December 6, 2015 | Phase 1 |
NCT02540512 | Loma Linda University |
Musculoskeletal Pain|Pain
|
July 27, 2017 | Early Phase 1 |
NCT05511025 | AstraZeneca |
Healthy Participants
|
September 20, 2022 | Phase 1 |
NCT03786029 | Tishreen University |
Local Anesthesia|Tooth Extraction
|
April 1, 2019 | Phase 2|Phase 3 |
NCT00585559 | Vanderbilt University Medical Center|National Institutes of Health (NIH)|National Institute of General Medical Sciences (NIGMS) |
Aneurysmal Subarachnoid Hemorrhage|Cerebral Vasospasm
|
April 2007 | Phase 3 |
NCT04837924 | General Hospital Sveti Duh |
Hip Fractures
|
April 21, 2021 | Phase 4 |
NCT00737048 | Janssen Pharmaceutical K.K. |
Pain|Postoperative Pain
|
March 2008 | Phase 3 |
NCT03584373 | Montefiore Medical Center |
Nephrolithiasis
|
July 27, 2018 | Phase 3 |
NCT04702256 | Assistance Publique - Hôpitaux de Paris|Roche Pharma AG |
Lupus Nephritis|Systemic Lupus Erythematosus (SLE)
|
December 9, 2021 | Phase 3 |
NCT03184649 | Cairo University |
Analgesic Drugs|Pain Relief
|
May 1, 2017 | Phase 1|Phase 2 |
NCT03641209 | Outi Aikio|University of Oulu |
Prematurity; Extreme|Low Birthweight, Extremely (999 Grams or Less)
|
September 3, 2018 | Phase 1|Phase 2 |
NCT04651556 | Menoufia University |
Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics
|
April 4, 2019 | Phase 4 |
NCT03185143 | Allodynic Therapeutics, LLC |
Migraine With and Without Aura
|
June 27, 2017 | Phase 2|Phase 3 |
NCT01422291 | Pamukkale University |
Low Back Pain
|
January 2011 | Phase 4 |
NCT03824938 | Columbia University|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
Multiple Sclerosis
|
April 30, 2019 | Phase 3 |
NCT02532322 | Children´s National Research Institute |
Arnold-Chiari Malformation|Posterior Fossa Tumors
|
November 2015 | Phase 2 |
NCT02495077 | National Institute of Allergy and Infectious Diseases (NIAID)|Clinical Trials in Organ Transplantation|Rho Federal Systems Division, Inc. |
Kidney Transplant
|
November 2, 2015 | Phase 2 |
NCT04626063 | Istanbul University |
Low Back Pain|Acute Pain
|
June 10, 2018 | Not Applicable |
NCT04660799 | Hoffmann-La Roche |
Lymphoma, Large B-Cell, Diffuse
|
February 24, 2021 | Phase 2 |
NCT02373514 | Akdeniz University |
Dysmenorrhea
|
January 2015 | Phase 4 |
NCT01053650 | University Hospital, Clermont-Ferrand |
Healthy Volunteers
|
January 2010 | Phase 1 |
NCT01946594 | Duke University|Centers for Disease Control and Prevention |
Fever
|
October 2013 | Phase 4 |
NCT01938144 | Pfizer |
Common Cold
|
April 2016 | Phase 3 |
NCT03701074 | University of South Alabama |
Patent Ductus Arteriosus|Preterm Infant|Bronchopulmonary Dysplasia
|
December 15, 2018 | Phase 2 |
NCT04148495 | Nantes University Hospital |
Pain Management
|
December 3, 2019 | Phase 4 |
NCT00092313 | Merck Sharp & Dohme LLC |
Postoperative Pain
|
June 2002 | Phase 3 |
NCT00325819 | Kaiser Permanente|Centers for Disease Control and Prevention |
Fever
|
May 2006 | Phase 3 |
NCT01115673 | McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.|Johnson & Johnson Consumer and Personal Products Worldwide |
Pain
|
June 2010 | Phase 3 |
NCT02974348 | University of Bamenda|Ministry of Science and Technology of the People´s Republic of China|National Institute for Parasitic Disease, Chinese Center for Disease Control and Prevention |
Drug Resistant Malaria Due to Plasmodium Falciparum
|
January 2013 | Phase 3 |
NCT01958866 | Chulalongkorn University |
Patients With Body Temperature Between 37.8-38.5|No Sign of Infection|No Liver and Kidney Problem
|
October 2013 | Phase 2|Phase 3 |
NCT03580980 | National Cancer Institute, Egypt |
Pediatric Cancer|Pain, Postoperative
|
April 1, 2015 | Not Applicable |
NCT04230252 | Janssen Korea, Ltd., Korea |
Healthy
|
January 7, 2020 | Phase 1 |
NCT03244540 | Medical University of Lublin |
Cesarean Section|Pain, Postoperative|Pain, Neuropathic
|
September 4, 2017 | Phase 4 |
NCT01476176 | GlaxoSmithKline |
Headache, Tension-Type
|
July 2009 | Phase 1 |
NCT01390441 | Merck Sharp & Dohme LLC |
Rheumatoid Arthritis
|
July 2011 | Phase 1 |
NCT00616018 | Kennon Heard|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.|Denver Health and Hospital Authority |
Drug Induced Liver Injury
|
August 2007 | Phase 4 |
NCT01474304 | Swedish Medical Center|Mallinckrodt |
Craniotomy
|
November 2011 | Phase 2 |
NCT03652818 | Nevakar, Inc. |
Dental Pain
|
June 15, 2018 | Phase 2 |
NCT00768716 | Tufts University|National Institute of General Medical Sciences (NIGMS) |
Pain|Fever|Hepatotoxicity
|
December 2008 | Phase 4 |
NCT01637818 | University Hospital, Basel, Switzerland|PD Dr. D. Frey, GZO Wetzikon, Wetzikon, Switzerland|Kantonsspital Olten|Prof. J. Metzger, Kantonsspital Luzern, Luzern, Switzerland |
Inguinal Hernia
|
September 1999 | Not Applicable |
NCT01048866 | Reckitt Benckiser LLC |
Pharyngitis
|
November 2009 | Phase 3 |
NCT03372382 | The University of Texas Health Science Center, Houston |
Opioid Use|Pain, Postoperative
|
December 13, 2017 | Phase 4 |
NCT03104816 | University of Southern California |
Fusion of Spine, Lumbar Region
|
October 2016 | Phase 4 |
NCT04149964 | William Beaumont Hospitals |
Post-operative Pain|Sinus Surgery
|
November 27, 2019 | Phase 4 |
NCT02094807 | Sahlgren´s University Hospital|Sahlgrenska University Hospital, Sweden |
Trauma|Rib Fractures|Surgery|Pain
|
April 2014 | Not Applicable |
NCT04530149 | Antonios Likourezos|Maimonides Medical Center |
Pain
|
November 1, 2021 | Phase 4 |
NCT03404908 | Medical University of Lublin |
Cesarean Section|Postoperative Pain
|
February 7, 2018 | Phase 4 |
NCT02355678 | Makassed General Hospital |
Postoperative Nausea and Vomiting
|
January 2015 | Not Applicable |
NCT04791761 | David Chi, MD|University of Pittsburgh |
Adenotonsillectomy|Post-operative Analgesia|Opioid Use
|
April 13, 2021 | Phase 1|Phase 2 |
NCT00399568 | Mallinckrodt |
Postoperative Pain|Hysterectomy
|
November 2006 | Phase 3 |
NCT03022253 | Postgraduate Institute of Medical Education and Research |
Patent Ductus Arteriosus
|
March 2016 | Phase 3 |
NCT02029638 | National Institute of Allergy and Infectious Diseases (NIAID)|Immune Tolerance Network (ITN) |
Kidney Transplantation
|
January 7, 2014 | Phase 2 |
NCT05417997 | RAAS Nutritionals, LLC|Kayseri City Hospital |
COVID-19 Respiratory Infection|FLU|Cold; Influenza|Bacterial Pneumonia|COVID-19 Pneumonia
|
May 29, 2021 | Phase 3 |
NCT04730297 | University of Roma La Sapienza |
To Control Pain After Third Molar Surgery
|
January 1, 2018 | Phase 4 |
NCT02999633 | Sanofi |
T-cell Type Acute Leukemia-Precursor|T-lymphoblastic Lymphoma+Leukaemia
|
March 8, 2017 | Phase 2 |
NCT00240786 | Johnson & Johnson Consumer and Personal Products Worldwide |
Osteoarthritis
|
April 2002 | Phase 3 |
NCT01464944 | Bayer |
Respiratory Tract Infections|Fever
|
November 2003 | Phase 4 |
NCT03588910 | Montefiore Medical Center |
Surgery
|
August 8, 2018 | Phase 2 |
NCT03648658 | Mette Cathrine Oerngreen|Elsass Foundation|Rigshospitalet, Denmark |
SMA II|Cerebral Palsy
|
February 18, 2019 | Phase 4 |
NCT03400267 | A.H. Tavenier|Isala |
STEMI|STEMI - ST Elevation Myocardial Infarction
|
February 16, 2018 | Phase 4 |
NCT03944044 | University Hospital, Caen |
Palliative Care
|
July 15, 2019 | Not Applicable |
NCT04571996 | Orion Corporation, Orion Pharma |
CNS Disease
|
October 29, 2020 | Phase 1 |
NCT00510536 | Probity Medical Research |
Arthritis|Arthralgia
|
July 2007 | Phase 4 |
NCT03117894 | Umeå University |
Breast Neoplasm Female|Regional Anesthesia|Anesthesia|Regional Anesthesia Morbidity|Anesthesia Morbidity
|
May 23, 2017 | Not Applicable |
NCT02797522 | Arrowhead Pharmaceuticals |
Hepatitis B
|
June 2016 | Phase 1 |
NCT02132416 | Sahlgren´s University Hospital|Sahlgrenska University Hospital, Sweden|Karolinska University Hospital |
Trauma|Flail Chest|Rib Fractures|Surgery
|
May 2014 | Not Applicable |
NCT02735122 | Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division|Johnson & Johnson Consumer and Personal Products Worldwide |
Post Operative Dental Pain
|
April 30, 2016 | Phase 3 |
NCT02519023 | University of Minnesota |
Acute Pain
|
July 2016 | Phase 4 |
NCT02706769 | University of Edinburgh|NHS Lothian |
Pain
|
November 25, 2016 | Not Applicable |
NCT05024825 | Albany Medical College |
Pain, Postoperative
|
August 4, 2017 | Phase 4 |
NCT01520298 | Lancaster General Hospital |
Pain|Hip Fracture
|
December 2011 | Phase 3 |
NCT01755728 | Hillel Yaffe Medical Center |
PDA
|
January 1, 2013 | Phase 3 |
NCT04416334 | Instituto de Investigación Marqués de Valdecilla|Gerencia de atención primaria área 1|Gerencia de atención primaria área 2|Gerencia Atencion Primaria Area 3|Gerencia de atención primaria área 4 |
SARS-CoV-2 Infection (COVID-19)
|
August 19, 2020 | Phase 3 |
NCT01104337 | Hopital Lariboisière |
Deep Venous Thrombosis|Pulmonary Embolism|Atrial Fibrillation|Stroke|Antiphospholipid Syndrome
|
March 2007 | Phase 4 |
NCT02095704 | Central South University |
Focus of Study: Pharmacokinetics Analysis, in Vivo Dissolution Studies
|
May 2013 | Phase 1 |
NCT01699815 | Duke University |
Osteoarthritis
|
October 2012 | Phase 4 |
NCT02867800 | Monica Bhatia|Columbia University |
Sickle Cell Disease|Graft Versus Host Disease
|
July 2016 | Phase 1 |
NCT04178109 | KAT General Hospital |
Postoperative Pain|Pain, Acute
|
January 10, 2019 | Phase 2 |
NCT03907176 | Heron Therapeutics |
Analgesia
|
April 5, 2019 | Phase 3 |
NCT00802087 | Egalet Ltd |
Pain
|
November 2008 | Phase 1 |
NCT04688788 | Rigshospitalet, Denmark|Odense University Hospital|Aarhus University Hospital|Aalborg University Hospital|Herlev Hospital|Hillerod Hospital, Denmark|Zealand University Hospital|Kolding Sygehus|Regional Hospital Holstebro|Hvidovre University Hospital|Hospital of South West Jutland, Esbjerg, Denmark|GCP unit, Copenhagen University Hospital|GCP-unit at Aarhus University Hospital, Aarhus, Denmark|Hospital of Southern Jutland, Sønderborg, Denmark|Hospital of Central Denmark Region, Viborg, Denmark|Danske Regioner |
Relapsing Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Primary Progressive Multiple Sclerosis
|
April 28, 2021 | Phase 3 |
NCT03997851 | University of Miami |
Pruritus
|
July 22, 2019 | Phase 1|Phase 2 |
NCT03389243 | Medical University of Silesia|Silesian University of Medicine |
Vitreoretinal Surgeries|Postoperative Nausea and Vomiting|Postoperative Pain
|
January 15, 2018 | Not Applicable |
NCT03704623 | Mansoura University|Amiri Hospital |
Acute Renal Colic|Ureteric Stone
|
May 1, 2019 | Phase 4 |
NCT03194555 | Allodynic Therapeutics, LLC |
Migraine With or Without Aura
|
August 25, 2017 | Phase 2 |
NCT02294071 | Lawson Health Research Institute |
Fever
|
December 2014 | Phase 4 |
NCT04165096 | Merck Sharp & Dohme LLC |
Carcinoma, Non-Small-Cell Lung
|
January 21, 2020 | Phase 2 |
NCT04551196 | Washington University School of Medicine |
Pain, Postoperative|Tonsillar Hypertrophy|Tonsillitis
|
September 28, 2020 | Phase 3 |
NCT01822821 | The Cleveland Clinic |
Pain
|
March 2013 | Not Applicable |
NCT02240407 | University of Florida|Lacerta Therapeutics |
Pompe Disease
|
October 17, 2017 | Phase 1 |
NCT02582996 | Ache Laboratorios Farmaceuticos S.A. |
Migraine
|
April 2020 | Phase 3 |
NCT03510910 | NYU Langone Health |
Hip Arthroscopy
|
April 10, 2018 | Phase 4 |
NCT00186628 | Stanford University|The Leukemia and Lymphoma Society|National Cancer Institute (NCI) |
Leukemia, Mast-Cell|Mantle-cell Lymphoma
|
June 2005 | Phase 2 |
NCT04835116 | Armed Forces Institute of Urology, Rawalpindi |
Pain|Postoperative Pain
|
April 11, 2019 | Phase 4 |
NCT03041948 | Alberta Children´s Hospital|University of Saskatchewan |
Hernia, Inguinal|Pain, Postoperative
|
September 1, 2015 | Not Applicable |
NCT03767933 | University of Alberta|University of Manitoba|Centre hospitalier de l´Université de Montréal (CHUM)|University of Western Ontario, Canada|University of Calgary|The Hospital for Sick Children|University of Ottawa |
Musculoskeletal Injury
|
April 20, 2019 | Phase 2 |
NCT03825198 | Dr M. B. Breebaart|University Hospital, Antwerp |
Pain, Postoperative|Anaesthesia|Surgery|Nerve Block|Anesthesia, Local|Back Pain|Spinal Fusion
|
August 1, 2019 | Phase 3 |
NCT03020875 | Hospital for Special Surgery, New York|Mallinckrodt |
Multimodal Analgesic Approach
|
January 2017 | Phase 4 |
NCT01038609 | AbbVie (prior sponsor, Abbott)|AbbVie |
Pain
|
December 2009 | Phase 2 |
NCT05366049 | Istanbul University-Cerrahpasa |
Fever|Heart Rate|Respiratory Rate|Pain
|
November 1, 2020 | Not Applicable |
NCT04933058 | Tel-Aviv Sourasky Medical Center |
Women Undergoing Oocyte Retrieval Procedures
|
December 5, 2021 | Not Applicable |
NCT02187614 | Hamad Medical Corporation |
Renal Colic|Urinary Calculi
|
August 2014 | Phase 4 |
NCT01079078 | Ranbaxy Laboratories Limited|Ranbaxy Inc. |
Healthy
|
October 2007 | Not Applicable |
NCT04574778 | Rothman Institute Orthopaedics |
Pain, Postoperative|Spine Surgery
|
March 18, 2021 | Phase 3 |
NCT03559985 | University Hospital, Clermont-Ferrand |
Neuropathic Pain
|
August 20, 2018 | Phase 2 |
NCT02821468 | Bioiberica|Artialis |
Osteoarthritis, Knee
|
June 2016 | Phase 4 |
NCT01552993 | St. Olavs Hospital|Norwegian University of Science and Technology |
Infant, Premature|Retinopathy
|
March 2012 | Not Applicable |
NCT03825809 | Henry Ford Health System |
Narcotic Use
|
January 22, 2019 | Phase 2|Phase 3 |
NCT02694653 | University of Tennessee Graduate School of Medicine |
Complications; Cesarean Section
|
October 2014 | Phase 1 |
NCT02778958 | Inonu University |
Bariatric Surgery Candidate|Obesity, Morbid
|
January 2016 | Phase 4 |
NCT01686646 | GlaxoSmithKline |
Common Cold
|
November 2011 | Phase 3 |
NCT03365622 | University of Rochester |
Nephrectomy
|
August 8, 2018 | Phase 4 |
NCT03445390 | Stanford University |
Pain
|
May 1, 2014 | Phase 4 |
NCT03679065 | Ain Shams University |
Shivering
|
March 1, 2018 | Phase 4 |
NCT04224558 | Cedars-Sinai Medical Center |
Crohn Disease
|
December 15, 2020 | Phase 1|Phase 2 |
NCT03968146 | Kasr El Aini Hospital |
Scoliosis Idiopathic|Scoliosis; Adolescence|Erector Spinae Plane Block
|
June 18, 2019 | Phase 2 |
NCT02910167 | Boehringer Ingelheim |
Acute Pain|Dysmenorrhea
|
October 15, 2016 | |
NCT03648437 | University of Oulu|Helsinki University Central Hospital|Turku University Hospital|Tartu University Hospital |
Patent Ductus Arteriosus
|
September 3, 2018 | Phase 1 |
NCT00493246 | Mallinckrodt |
Pain|Fever
|
June 2007 | Phase 1 |
NCT03631433 | Ohio State University |
Pain, Postoperative
|
February 10, 2016 | Phase 4 |
NCT01872871 | Dr. Sami Ulus Children´s Hospital |
Retinopathy of Prematurity
|
January 2013 | Not Applicable |
NCT00490009 | Susan Knox|Corixa Corporation|GlaxoSmithKline|Stanford University |
Lymphoma
|
September 2004 | Phase 2 |
NCT03618823 | David Chi, MD|University of Pittsburgh |
Adenotonsillectomy|Post-operative Analgesia|Opioid Use
|
October 25, 2018 | Phase 1|Phase 2 |
NCT03521102 | Montefiore Medical Center |
Acute Pain
|
August 20, 2018 | Phase 2 |
NCT01476215 | GlaxoSmithKline |
Healthy Subjects
|
November 2009 | Phase 1 |
NCT00382083 | Mountain States Tumor and Medical Research Institute |
Breast Pain
|
March 2006 | Phase 4 |
NCT04691856 | Inonu University |
Postoperative Pain Management
|
December 24, 2020 | Not Applicable |
NCT02236130 | University of Mississippi Medical Center |
Pediatric Extremity Fracture|Pediatric Extremity Soft Tissue Injury
|
June 2014 | Not Applicable |
NCT03482232 | Universidad Miguel Hernandez de Elche|Osasunbidea|Servicio Madrileño de Salud, Madrid, Spain|Fondo de Investigacion Sanitaria|AQuAS|Agencia de Calidad Sanitaria de Andalucía|Ministerio de Sanidad, Servicios Sociales e Igualdad|Servicio Aragones De Salud|Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana|Generalitat Valenciana|MurciaSalud|Osakidetza|Castilla-La Mancha Health Service |
Overdose|Adverse Event
|
October 14, 2018 | |
NCT04202406 | Cairo University |
Symptomatic Irreversible Pulpitis
|
January 9, 2021 | Not Applicable |
NCT00000875 | National Institute of Allergy and Infectious Diseases (NIAID) |
HIV Infections
|
Not Applicable | |
NCT03482492 | Yeditepe University Hospital |
Lumbar Disc Herniation
|
March 20, 2014 | Not Applicable |
NCT02440399 | HaEmek Medical Center, Israel |
Post Cesarean Pain Management
|
July 2015 | Not Applicable |
NCT04905563 | Le Bonheur Children´s Hospital|The Campbell Foundation |
Supracondylar Humerus Fracture
|
June 7, 2021 | Phase 4 |
NCT01216163 | Pfizer |
Pain
|
October 2010 | Phase 3 |
NCT01465009 | Bayer |
Common Cold|Pharyngitis|Tonsillitis
|
November 2003 | Phase 4 |
NCT02433912 | Universidade Federal Fluminense |
Gingival Recession
|
June 2002 | Phase 4 |
NCT04469413 | Ankara University |
Patent Ductus Arteriosus in Preterm Infants
|
January 1, 2019 | |
NCT03597308 | Rothman Institute Orthopaedics |
Post-operative Pain
|
March 17, 2017 | Not Applicable |
NCT02449369 | AdventHealth|Sagent Pharmaceuticals Inc. |
Unilateral Knee Arthroplasty
|
April 2015 | Phase 4 |
NCT03988075 | Medstar Health Research Institute |
Pain|Thyroidectomy
|
July 24, 2018 | Not Applicable |
NCT04837014 | McGill University Health Centre+Research Institute of the McGill University Health Centre |
Pain, Postoperative|Opioid Use
|
July 4, 2022 | Not Applicable |
NCT04360135 | Montefiore Medical Center |
Post Operative Pain
|
May 6, 2020 | Phase 2|Phase 3 |
NCT04630834 | New York City Health and Hospitals Corporation |
Pain, Acute
|
March 30, 2021 | Phase 4 |
NCT03547427 | University of Virginia |
Type 1 Diabetes Mellitus
|
May 20, 2018 | Not Applicable |
NCT02156154 | The Cleveland Clinic |
Postoperative Pain
|
December 2014 | Phase 3 |
NCT03056391 | Menzies School of Health Research |
Malaria
|
October 2016 | Phase 3 |
NCT03061734 | Allodynic Therapeutics, LLC |
Migraine With or Without Aura
|
February 18, 2017 | Phase 2 |
NCT02477007 | Assistance Publique - Hôpitaux de Paris |
Pain|Long-bone Fractures
|
December 3, 2015 | Phase 3 |
NCT05022810 | GlaxoSmithKline |
Pain
|
August 23, 2021 | Phase 1 |
NCT02369211 | Brigham and Women´s Hospital|Mallinckrodt |
Prostatectomy|Pain
|
September 2015 | Phase 4 |
NCT01182974 | Barzilai Medical Center|Hadassah Medical Organization |
Fever|Sepsis
|
August 2010 | Phase 3 |
NCT01063842 | Janssen Korea, Ltd., Korea |
Osteoarthritis
|
August 2005 | Phase 4 |
NCT02417337 | University of Khartoum |
Pain|Postoperative Pain|Irreversible Pulpitis
|
August 2012 | Phase 2 |
NCT01086540 | National Institute of Allergy and Infectious Diseases (NIAID)|Autoimmunity Centers of Excellence|Rho Federal Systems Division, Inc. |
Systemic Sclerosis-Associated PAH
|
June 24, 2011 | Phase 2 |
NCT03058224 | IgNova GmbH|SCOPE International AG|Klinar CRO|CenTrial GmbH|Pharmasolutions4U|idv Data Analysis and Study Planning |
Chronic Widespread Pain|Fibromyalgia
|
February 16, 2017 | Not Applicable |
NCT03201393 | Allodynic Therapeutics, LLC |
Chronic Low Back Pain|Lumbar Radiculopathy
|
August 15, 2017 | Phase 2 |
NCT02267772 | The University of Texas Health Science Center, Houston |
Pain Management in Pregnant Women
|
January 2014 | Not Applicable |
NCT03472872 | Spectrum Health - Lakeland|Michigan State University |
Headache
|
September 5, 2017 | Phase 4 |
NCT01209455 | University of Edinburgh|NHS Lothian |
Poisoning
|
January 2011 | Not Applicable |
NCT04523740 | University Hospital Bispebjerg and Frederiksberg |
Pain, Chronic|Pain, Medication|Pain, Discontinuation
|
August 2020 | Not Applicable |
NCT01075243 | GlaxoSmithKline |
Post-surgical Dental Pain
|
November 2009 | Phase 4 |
NCT05143762 | Benha University |
Analgesia
|
October 15, 2021 | Phase 2 |
NCT04622735 | Unither Pharmaceuticals, France|EXCELYA Bordeaux |
Acute Pain
|
February 22, 2020 | Phase 3 |
NCT00012857 | US Department of Veterans Affairs|VA Office of Research and Development |
Dementia|Alzheimer Disease, Pain|Behavior, Agitation
|
Phase 2 | |
NCT02750163 | Università Politecnica delle Marche |
Sepsis and Septic Shock
|
July 5, 2017 | |
NCT00188071 | University Hospital, Angers |
Abortion, Induced
|
September 2002 | Not Applicable |
NCT02267057 | University of Bergen |
Depression|Pain|Dementia
|
August 2014 | Phase 4 |
NCT04593160 | Cairo University |
Symptomatic Irreversible Pulpitis
|
January 2021 | Not Applicable |
NCT03913559 | St. Jude Children´s Research Hospital|Pfizer |
Acute Lymphoblastic Leukemia
|
May 14, 2019 | Phase 2 |
NCT03128346 | Western University, Canada |
Postoperative Pain|Nerve Block|Cardiac Surgery
|
October 1, 2017 | Not Applicable |
NCT02578251 | Ain Shams Maternity Hospital |
Analgesia, Obstetrical
|
October 2015 | Phase 2 |
NCT05603832 | Arthritis Innovation Corporation|Allucent |
Post Operative Pain
|
November 2022 | Phase 3 |
NCT03295214 | Massachusetts Eye and Ear Infirmary |
Acetaminophen
|
March 28, 2018 | Phase 3 |
NCT02237989 | Eskisehir Osmangazi University |
Knee Osteoarthritis
|
January 2013 | Not Applicable |
NCT03385057 | Massachusetts Eye and Ear Infirmary|Emory University|University Hospitals Cleveland Medical Center|Madigan Army Medical Center|United States Naval Medical Center, Portsmouth|Rady Children´s Hospital, San Diego |
Tonsillectomy With or Without Adenoidectomy
|
September 2018 | Phase 1 |
NCT02280239 | University of British Columbia|Vancouver Coastal Health Research Institute |
Critical Illness|Fever
|
May 2015 | Phase 4 |
NCT03355248 | ProMedica Health System |
Pain, Postoperative|Cesarean Section Complications|Postpartum Disorder|Opioid Use
|
August 18, 2017 | Not Applicable |
NCT03035045 | Rajavithi Hospital |
Amniocentesis
|
November 2016 | Not Applicable |
NCT03011567 | MemorialCare Health System |
Hypertension, Pregnancy-Induced
|
January 2017 | Not Applicable |
NCT00855049 | University of Texas Southwestern Medical Center|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.|American College of Medical Toxicology |
Pharmacokinetics
|
April 2009 | Not Applicable |
NCT01998971 | Janssen Research & Development, LLC |
Multiple Myeloma
|
February 18, 2014 | Phase 1 |
NCT02622802 | University Hospital, Gasthuisberg |
Pregnancy
|
November 2012 | Not Applicable |
NCT01073709 | Ranbaxy Laboratories Limited|Ranbaxy Inc. |
Healthy
|
November 2007 | Not Applicable |
NCT03648021 | Fondation Ophtalmologique Adolphe de Rothschild |
Brain Injuries
|
April 10, 2018 | Phase 4 |
NCT00528658 | Chinese University of Hong Kong|Hong Kong Academy of Medicine |
Soft Tissue Injuries
|
January 2005 | Phase 2 |
NCT03222518 | University of Monastir |
Acute Pain Due to Trauma
|
March 1, 2017 | Phase 3 |
NCT04769557 | Melaka Manipal Medical College |
Impacted Third Molar Tooth
|
March 4, 2017 | Phase 4 |
NCT00890604 | University of Washington|Gaymar Industries, Inc. |
Subarachnoid Hemorrhage|Severe Traumatic Brain Injury
|
July 2009 | Not Applicable |
NCT02422966 | Aziende Chimiche Riunite Angelini Francesco S.p.A |
Ductus Arteriosus, Patent
|
December 2015 | Phase 2 |
NCT02929212 | Columbia University|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Morbid Obesity
|
September 2009 | Not Applicable |
NCT05088876 | University Hospital Inselspital, Berne|Swiss National Science Foundation |
Pain
|
August 15, 2022 | Phase 4 |
NCT00631514 | University Hospital of Split|Dr Ivancica Pavlicevic Family Practice Office |
Hypertension
|
January 2005 | Phase 4 |
NCT05556356 | Indiana Hand to Shoulder Center |
Carpometacarpal Osteoarthritis
|
September 13, 2022 | Phase 4 |
NCT00137566 | Bandim Health Project |
Malaria|Falciparum
|
May 2004 | Phase 4 |
NCT05129137 | Unither Pharmaceuticals, France|Accutest Research Laboratories (I) Pvt. Ltd. |
Healthy Volunteers
|
November 29, 2021 | Phase 1 |
NCT04779567 | Pontificia Universidad Catolica de Chile |
Acute Pain|Cancer Pain
|
June 10, 2019 | Phase 4 |
NCT00771875 | University of Cincinnati |
Graft Rejection
|
September 2008 | Phase 2 |
NCT03818919 | Henry Ford Health System |
Rotator Cuff Tear
|
January 22, 2019 | Phase 2 |
NCT05529290 | Yuzuncu Y?l University |
Temporomandibular Disorder
|
July 16, 2019 | Phase 4 |
NCT02091830 | Northern Orthopaedic Division, Denmark |
Knee Osteoarthritis
|
January 2013 | |
NCT01019980 | Novartis Pharmaceuticals|Novartis |
Fever
|
March 2010 | Phase 4 |
NCT03540030 | OrthoCarolina Research Institute, Inc. |
Opioid Use|Shoulder Osteoarthritis|Avascular Necrosis|Rotator Cuff Tear|Arthritis;Inflammatory
|
September 2016 | Phase 4 |
NCT00942565 | The University of Hong Kong |
Postoperative Pain
|
April 2007 | Phase 4 |
NCT02811991 | Jiangsu HengRui Medicine Co., Ltd. |
Post-operative Analgesia
|
June 2016 | Phase 2|Phase 3 |
NCT02209181 | McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.|Johnson & Johnson Consumer and Personal Products Worldwide |
Pain
|
August 2014 | Phase 2 |
NCT01568749 | GlaxoSmithKline |
Analgesia
|
December 2008 | Phase 1 |
NCT02845271 | Genzyme, a Sanofi Company|Sanofi |
Osteoarthritis
|
July 21, 2016 | Phase 2 |
NCT02902666 | Aziende Chimiche Riunite Angelini Francesco S.p.A|Cross Research S.A. |
Healthy
|
April 2016 | Phase 1 |
NCT04424420 | Prof. Jürgen Brockmöller|University Hospital Ulm|University of Göttingen |
Empathy
|
November 7, 2019 | Phase 1 |
NCT05401916 | Bezmialem Vakif University |
Postoperative Pain Management
|
June 10, 2022 | Not Applicable |
NCT03763084 | Xiangya Hospital of Central South University|Yale University |
Acetaminophen|Delirium in Old Age
|
February 15, 2019 | Early Phase 1 |
NCT01394731 | King Abdulaziz University|King Abdulaziz Medical City |
Labor Pain
|
December 2010 | Phase 4 |
NCT02994940 | University of California, Davis |
Tonsillectomy|Adenoidectomy
|
August 28, 2017 | Phase 4 |
NCT05070650 | Sandoz |
Common Cold
|
September 20, 2023 | Phase 3 |
NCT00702416 | University of Parma |
Shoulder|Orthopedic Surgery|Nerve Block
|
May 2008 | Phase 4 |
NCT04625608 | King´s College Hospital NHS Trust|Barts & The London NHS Trust |
Fasting
|
October 6, 2020 | Phase 4 |
NCT02815189 | Universidad Autonoma de Baja California |
Pain
|
February 2014 | Phase 2 |
NCT00344045 | Bristol-Myers Squibb |
Pain
|
April 2006 | Phase 4 |
NCT01817829 | Ain Shams University |
Labor Pain
|
December 2011 | Phase 3 |
NCT03883893 | Children´s Hospital Medical Center, Cincinnati |
Tonsillectomy|Adenoidectomy
|
December 2021 | Phase 2 |
NCT01465984 | Tehran University of Medical Sciences |
Acute Pain
|
November 2011 | Phase 4 |
NCT02198378 | University Hospital, Toulouse |
Acute Coronary Syndrome
|
November 2014 | Phase 4 |
NCT03918135 | Pamukkale University |
Fever
|
January 1, 2019 | Phase 4 |
NCT04038346 | Desiree Neville, MD|University of Pittsburgh |
Lyme Arthritis|Lyme Disease|Arthritis
|
October 1, 2019 | Phase 3 |
NCT01770041 | University of Edinburgh|NHS Lothian |
Liver Resection|Paracetamol Administration
|
February 2013 | |
NCT00110474 | Rottapharm |
Knee Osteoarthritis
|
May 2000 | Phase 3 |
NCT01891084 | The University of Hong Kong |
Influenza
|
July 2013 | Phase 4 |
NCT04529356 | Huashan Hospital |
Headache|Pituitary Tumor|Acromegaly
|
September 1, 2020 | Not Applicable |
NCT00406679 | Baxter Healthcare Corporation |
Pain, Postoperative
|
November 2006 | Phase 3 |
NCT02320708 | Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.|Johnson & Johnson Consumer and Personal Products Worldwide |
Dental Pain
|
December 31, 2014 | Phase 2 |
NCT00487110 | University Hospital, Clermont-Ferrand |
Pain
|
June 2008 | Phase 4 |
NCT00594867 | University of Illinois at Chicago |
Healthy
|
December 2006 | Phase 4 |
NCT01551836 | GlaxoSmithKline |
Healthy Volunteer
|
June 2009 | Phase 1 |
NCT02571361 | Daniel Hägi-Pedersen|Copenhagen Trial Unit, Center for Clinical Intervention Research|Naestved Hospital |
Pain, Postoperative
|
November 2015 | Phase 4 |
NCT01656057 | Filip Krag Knop|University of Copenhagen|University Hospital, Gentofte, Copenhagen |
To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion
|
July 2012 | Not Applicable |
NCT03996564 | San Antonio Military Medical Center |
Low Back Pain, Mechanical
|
February 22, 2016 | Not Applicable |
NCT03024814 | King Saud Medical City |
Intraventricular Haemorrhage Neonatal
|
October 2016 | Phase 3 |
NCT05241054 | Mansoura University |
Patient With Nasolacrimal Duct Obstruction|External Dacryocystorhinostomy Operation
|
March 2022 | Not Applicable |
NCT03399318 | University of Rochester|National Institute of Neurological Disorders and Stroke (NINDS) |
Malaria|Seizures|Coma|Parasitemia|Hyperpyrexia
|
July 2, 2018 | Phase 2 |
NCT02227316 | University of California, Los Angeles|Sponsor Name Pending |
Symptomatic Uterine Fibroids and Adenomyosis
|
August 2014 | Phase 4 |
NCT04015908 | University of Utah |
Opioid Use
|
August 1, 2019 | Phase 4 |
NCT00200590 | Nantes University Hospital |
Pain
|
December 2003 | Not Applicable |
NCT04939987 | Wake Forest University Health Sciences |
Radical Prostatectomies
|
August 2022 | Phase 2|Phase 3 |
NCT04694300 | Hersh, Elliot V., DMD, MS, PhD|University of Pennsylvania |
Osseointegrated Dental Implantation|Pain, Acute
|
February 7, 2021 | Phase 4 |
NCT01630343 | Queen Elizabeth Hospital, Hong Kong |
Geriatric Hip Fracture Pain Management
|
January 2010 | Phase 2 |
NCT02691754 | Azienda Unità Sanitaria Locale Reggio Emilia |
Osteoarthritis
|
November 2012 | Not Applicable |
NCT00694369 | Organon and Co |
Postoperative Dental Pain
|
June 2008 | Phase 3 |
NCT02804126 | Micha? Borys|Medical University of Lublin |
Cesarean Section|Pain Management|Neuropathic Pain
|
June 2016 | Phase 4 |
NCT05557344 | Dr. Niina Kleiber|St. Justine´s Hospital |
Pain
|
April 21, 2021 | Phase 4 |
NCT03553498 | Albert Einstein College of Medicine |
Acute Pain
|
November 27, 2018 | Phase 3 |
NCT03910088 | Cairo University |
Post-Dural Puncture Headache
|
April 20, 2019 | Phase 4 |
NCT03929640 | Milton S. Hershey Medical Center |
Pain, Postoperative|Opioid Use
|
August 5, 2019 | Phase 3 |
NCT04278625 | Peter Winch|Nationwide Children´s Hospital |
Congenital Heart Disease
|
March 23, 2021 | |
NCT02654860 | Sintetica SA|Cross S.A. |
Phase 1: Pain Management|Phase 2: Pain Management
|
November 2016 | Phase 1|Phase 2 |
NCT02359175 | Odense University Hospital |
Lung Neoplasms|Pain|Immune Suppression
|
February 2015 | Phase 4 |
NCT03041779 | Clinical Research Centre, Malaysia |
Perineal Tear|Perineal Laceration (Obstetric)
|
October 2015 | Phase 2 |
NCT04066426 | Yuzuncu Y?l University |
Temporomandibular Disorder
|
March 1, 2018 | Phase 4 |
NCT04645966 | Pfizer |
Meningococcal Vaccine
|
November 26, 2020 | Phase 2 |
NCT02160301 | University of North Carolina, Chapel Hill |
Post Operative Pain Control
|
November 2017 | Phase 4 |
NCT00210847 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C.|PriCara, Unit of Ortho-McNeil, Inc. |
Diabetic Neuropathies
|
December 2003 | Phase 3 |
NCT01767428 | GlaxoSmithKline |
Fever|Headache Disorders|Pain
|
April 2010 | Phase 1 |
NCT03020966 | Hospital for Special Surgery, New York|Mallinckrodt |
Pain, Postoperative|Opioid Use
|
February 16, 2017 | Phase 4 |
NCT04294459 | Sanofi |
Immune System Disorder
|
June 18, 2020 | Phase 1|Phase 2 |
NCT03677830 | St. Louis University |
Pain, Postoperative|Premature Infant|Opioid Use
|
April 19, 2019 | Phase 4 |
NCT00699114 | Ullevaal University Hospital|University of Oslo|Oslo University Hospital |
Surgery
|
June 2007 | Phase 4 |
NCT00377403 | Washington University School of Medicine|National Institute of Allergy and Infectious Diseases (NIAID) |
Acute Respiratory Infections|Acute Rhinosinusitis
|
October 2006 | Phase 4 |
NCT00240851 | Johnson & Johnson Consumer and Personal Products Worldwide|McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. |
Pain
|
Phase 4 | |
NCT04026464 | University of Florida |
Patent Ductus Arteriosus
|
April 2021 | Phase 2 |
NCT02465255 | IRCCS Burlo Garofolo |
Abdominal Pain
|
March 2015 | Phase 3 |
NCT02085577 | Rigshospitalet, Denmark|Glostrup University Hospital, Copenhagen |
Postoperative Pain|Chronic Pain|Analgesics
|
May 2014 | Phase 4 |
NCT02671851 | Istanbul University |
Pain, Postoperative
|
January 2014 | |
NCT01073748 | Tel-Aviv Sourasky Medical Center |
Asthma
|
March 2010 | Not Applicable |
NCT05298683 | Hellenic Society of Hematology|Sanofi |
Multiple Myeloma|Renal Impairment|Neoplasms, Plasma Cell|Neoplasms by Histologic Type|Neoplasms|Paraproteinemias|Blood Protein Disorders|Hematologic Diseases
|
May 2022 | Phase 2 |
NCT03554005 | Merck Sharp & Dohme LLC |
Neoplasms
|
December 29, 1997 | Phase 1 |
NCT03265782 | Ain Shams University |
Patent Ductus Arteriosus
|
June 2015 | Phase 4 |
NCT01024348 | Shaare Zedek Medical Center |
Postoperative Pain
|
December 2009 | Not Applicable |
NCT03885596 | Concentric Analgesics |
Pain
|
March 25, 2019 | Phase 2 |
NCT02714179 | Baskent University |
Cesarean Section; Dehiscence
|
May 2015 | Phase 4 |
NCT02244437 | Mountain Medicine Society of Nepal |
Acute Mountain Sickness, Blood Oxygen Saturation, Headache
|
October 2014 | Phase 4 |
NCT05602064 | Alexandria University |
Post-operative Pain
|
November 1, 2022 | Phase 4 |
NCT02746263 | Mallinckrodt |
Acute Pain, Postoperative
|
April 27, 2016 | Phase 4 |
NCT02614118 | Azad University of Medical Sciences |
Irreversible Pulpitis
|
September 2015 | Phase 2 |
NCT04018612 | Nevakar, Inc. |
Pain, Postoperative|Dental Pain
|
April 25, 2019 | Phase 2 |
NCT05509244 | The Catholic University of Korea |
Gynecologic Disease
|
September 9, 2022 | Not Applicable |
NCT04920838 | ANRS, Emerging Infectious Diseases|University of Bordeaux|Institut National de la Santé Et de la Recherche Médicale, France|PACCI Program|Alliance for International Medical Action|Centre Muraz|Barcelona Institute for Global Health |
Covid19|Covid19 Drug Treatment|Severe Acute Respiratory Syndrome Coronavirus 2|SARS-CoV2 Infection
|
April 12, 2021 | Phase 2|Phase 3 |
NCT03496545 | University of California, San Francisco |
Subarachnoid Hemorrhage|Subdural Hematoma|Traumatic Brain Injury|Ischemic Stroke|Fever|Intracerebral Hemorrhage
|
November 30, 2018 | Phase 1|Phase 2 |
NCT03055507 | University of Washington |
Chronic Rhinosinusitis (Diagnosis)
|
April 1, 2017 | Phase 2|Phase 3 |
NCT04949477 | Benha University |
Anxiety
|
July 1, 2021 | Phase 2 |
NCT03016650 | Muharrem Ucar|Inonu University |
Analgesia|Percutaneous Nephrolithotomy
|
January 2017 | Phase 4 |
NCT03697746 | Pamukkale University |
Dysmenorrhea
|
October 1, 2018 | Not Applicable |
NCT00969176 | Universitaire Ziekenhuizen KU Leuven |
Pain|Fever
|
September 2009 | Phase 2|Phase 3 |
NCT04726878 | Medical University of Lublin |
Breast Cancer|Pain, Acute|Anesthesia, Local
|
February 1, 2021 | Phase 4 |
NCT04429022 | State University of New York at Buffalo |
Pain, Postoperative
|
October 15, 2020 | Phase 3 |
NCT04681105 | City of Hope Medical Center|National Cancer Institute (NCI) |
Recurrent Acute Leukemia|Recurrent B Acute Lymphoblastic Leukemia|Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Hairy Cell Leukemia|Recurrent Hematologic Malignancy|Recurrent Hodgkin Lymphoma|Recurrent T Acute Lymphoblastic Leukemia|Refractory Acute Leukemia|Refractory B Acute Lymphoblastic Leukemia|Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Hairy Cell Leukemia|Refractory Hematologic Malignancy|Refractory Hodgkin Lymphoma|Refractory T Acute Lymphoblastic Leukemia|Systemic Mastocytosis
|
November 18, 2020 | Phase 1 |
NCT04407234 | Eli Lilly and Company |
Overweight|Obesity|Diabetes Mellitus, Type 2
|
September 15, 2020 | Phase 1 |
NCT03323047 | London Health Sciences Centre |
Tonsillitis
|
March 1, 2018 | Phase 4 |
NCT00378937 | University Hospitals Bristol and Weston NHS Foundation Trust|National Cancer Institute (NCI) |
Pain|Unspecified Adult Solid Tumor, Protocol Specific
|
January 2004 | Phase 4 |
NCT00564629 | Mallinckrodt |
Fever
|
August 2007 | Phase 3 |
NCT02819414 | Shaare Zedek Medical Center |
Patent Ductus Arteriosus
|
June 2016 | Phase 2 |
NCT03428503 | Pamukkale University |
Musculoskeletal Pain
|
December 2015 | Phase 4 |
NCT02219698 | Helsinki University Central Hospital|Vatsatautien tutkimussäätiö - foundation|Mary and Georg Ehrnroot´s foundation|Finnish Surgical society|Martti I. Turunen Foundation|Governmental competitive funds (EVO) |
Diverticulitis
|
July 2014 | Not Applicable |
NCT02855866 | Centre Hospitalier Universitaire Dijon |
Thyroidectomy|Post-operative Swallowing Disorders
|
September 3, 2013 | Not Applicable |
NCT02061774 | Texas Tech University Health Sciences Center |
Low Back Pain
|
October 2013 | Phase 4 |
NCT02046382 | TriHealth Inc. |
Cesarean Section|Pain, Postoperative
|
January 2014 | Phase 4 |
NCT01359020 | Mantecorp Industria Quimica e Farmaceutica Ltd. |
Fever
|
January 2007 | Phase 4 |
NCT00282347 | Genentech, Inc. |
Lupus Nephritis
|
January 2006 | Phase 3 |
NCT02973581 | Medical University of Silesia|Silesian University of Medicine |
Vitreoretinal Surgeries|Postoperative Nausea and Vomiting|Postoperative Pain
|
February 2016 | Not Applicable |
NCT03974932 | Heron Therapeutics |
Analgesia
|
June 5, 2019 | Phase 3 |
NCT05154682 | Rothman Institute Orthopaedics |
Pain, Postoperative
|
November 30, 2021 | Phase 3 |
NCT00508495 | Baxter Healthcare Corporation|MDS Pharma Services |
Pain, Postoperative
|
August 2007 | Phase 3 |
NCT01246713 | Beth Israel Deaconess Medical Center|Harvard University|National Center for Research Resources (NCRR) |
Acetaminophen Metabolism|Acetaminophen Poisoning|Drug Metabolism by Excipients
|
December 2010 | Not Applicable |
NCT01530880 | Columbia University|Cumberland Pharmaceuticals |
Fever
|
October 2012 | Phase 4 |
NCT03820193 | Henry Ford Health System |
Meniscus Disorder|Narcotic Use
|
January 22, 2019 | Early Phase 1 |
NCT02181387 | Wake Forest University Health Sciences |
Pain
|
September 5, 2013 | Phase 4 |
NCT04397913 | Shandong University|West China Second University Hospital |
Patent Ductus Arteriosus
|
May 25, 2020 | |
NCT01635608 | University Medicine Greifswald |
Gastrointestinal Motility Disorder
|
April 2011 | Phase 1 |
NCT01069055 | Diskapi Teaching and Research Hospital |
Inguinal Hernia|Postoperative Pain
|
February 2010 | Phase 3 |
NCT02086747 | Mustafa Kemal University |
Abdominal Hysterectomy (& Wertheim)
|
March 2013 | Phase 4 |
NCT04265456 | Nevakar, Inc. |
Postoperative Pain
|
January 14, 2020 | Phase 1 |
NCT01810458 | University of Florida |
Liver Fibrosis|Alpha-1 Antitrypsin Deficiency|AAT Deficiency|AATD
|
October 2013 | |
NCT01536158 | Zekai Tahir Burak Women´s Health Research and Education Hospital |
Patent Ductus Arteriosus
|
February 2012 | Phase 4 |
NCT02102555 | MercyOne Des Moines Medical Center |
Post Operative Pain|Post Operative Nausea and Vomiting
|
October 2013 | Phase 3 |
NCT01073670 | Queen´s University |
Hemorrhage
|
August 2000 | Phase 4 |
NCT05488847 | Henry Ford Health System |
Shoulder Arthropathy|Shoulder Pain
|
June 25, 2022 | Phase 4 |
NCT03049878 | University of Roma La Sapienza |
To Control Pain After Third Molar Surgery
|
February 21, 2013 | Phase 4 |
NCT04093219 | Beth Israel Deaconess Medical Center|National Institute on Aging (NIA) |
Delirium in Old Age|Delirium|Coronary Artery Disease
|
August 11, 2020 | Phase 3 |
NCT02974114 | GlaxoSmithKline |
Pain
|
October 31, 2016 | Phase 4 |
NCT00598559 | Mallinckrodt |
Acute Pain|Fever
|
January 2008 | Phase 3 |
NCT03554018 | Montefiore Medical Center |
Low Back Pain
|
October 16, 2018 | Phase 3 |
NCT02677532 | University of Genova |
Postoperative Pain
|
December 2011 | Phase 4 |
NCT01264965 | University of Chicago |
Arthritis|Pain|Cognitive Impairment
|
January 2011 | Phase 4 |
NCT01606319 | Milton S. Hershey Medical Center|National Heart, Lung, and Blood Institute (NHLBI) |
Asthma|Wheezing
|
February 2013 | Phase 3 |
NCT04175509 | Aultman Health Foundation |
Postoperative Pain|Opioid Use|Acetaminophen
|
December 23, 2019 | Phase 4 |
NCT01906762 | Seyed Mehdi Pourafzali|Isfahan University of Medical Sciences |
Renal Colic
|
July 2012 | Phase 2 |
NCT02205983 | University of Chicago|National Institute on Drug Abuse (NIDA) |
Healthy
|
January 2015 | Not Applicable |
NCT01235949 | GlaxoSmithKline |
Infections, Streptococcal
|
November 12, 2010 | Phase 4 |
NCT02212990 | Duke University|Centers for Disease Control and Prevention |
Fever
|
September 2014 | Not Applicable |
NCT04074174 | Novo Nordisk A+S |
Overweight|Obesity
|
September 12, 2019 | Phase 1 |
NCT03261310 | Brooke Army Medical Center |
Postoperative Pain
|
May 2013 | Not Applicable |
NCT03468920 | TriHealth Inc. |
Pain, Postoperative
|
April 1, 2018 | Phase 4 |
NCT00325949 | Abbott |
Chronic Low Back Pain
|
May 2006 | Phase 3 |
NCT03523988 | University of Washington |
NSAID|Pain Management
|
May 2, 2017 | Phase 4 |
NCT02539979 | Sheba Medical Center |
Chronic Lower Back Pain|Lumbar Facet Syndrome
|
August 2015 | Not Applicable |
NCT03859024 | University of Alabama at Birmingham |
Pain, Postoperative|Urethral Stricture
|
March 22, 2019 | Phase 4 |
NCT02313675 | John Fowler|University of Pittsburgh |
Postoperative Pain|Carpal Tunnel Release|Distal Radius Fracture
|
May 2015 | Phase 4 |
NCT02432456 | Medical College of Wisconsin |
Wounds and Injuries|Rib Fractures
|
September 2015 | Phase 4 |
NCT01641289 | University of Oxford |
Malaria
|
July 10, 2012 | Not Applicable |
NCT05361824 | National Institute of Cardiovascular Diseases, Karachi |
Coronary Artery Disease|Post Operative Pain|Analgesia|Coronary Artery Bypass Grafting Surgery
|
January 1, 2021 | Phase 4 |
NCT00147355 | Kirby Institute|The University of New South Wales |
HIV Infections
|
November 2005 | Phase 3 |
NCT01551797 | GlaxoSmithKline |
Pain
|
May 2010 | Phase 1 |
NCT00324467 | British Columbia Cancer Agency|Hoffmann-La Roche |
Lymphoma, Non-Hodgkin|Advanced Stage Diffuse Large B-Cell Non-Hodgkin´s Lymphoma
|
August 2006 | Phase 2 |
NCT03011905 | Oslo University Hospital |
Brachial Plexus Block|Pain, Postoperative
|
January 2017 | Phase 3 |
NCT01513668 | Ranbaxy Laboratories Limited|Ranbaxy Inc. |
Healthy
|
May 2006 | Not Applicable |
NCT02514538 | Jordi Gol i Gurina Foundation |
Hypertension|Chronic Disease of Musculoskeletal System
|
February 2012 | Phase 4 |
NCT02590900 | Universitaire Ziekenhuizen KU Leuven |
Pain
|
June 2010 | |
NCT02601911 | Azad University of Medical Sciences |
Irreversible Pulpitis
|
September 2015 | Phase 2 |
NCT02025634 | AdventHealth|University of Central Florida |
Pain, Postoperative
|
November 2013 | Phase 4 |
NCT02934191 | Children´s Hospital of Philadelphia|Pfizer |
Tonsillectomy
|
June 2016 | Phase 2 |
NCT01321710 | University of California, San Francisco|National Institute of Nursing Research (NINR) |
Pregnancy|Postpartum Period|Sleep Disturbance
|
December 2004 | Not Applicable |
NCT02183688 | Boehringer Ingelheim |
Migraine Disorders
|
September 1998 | Phase 3 |
NCT03182595 | Hospital da Luz, Portugal|Universidade Nova de Lisboa |
Healthy Volunteers
|
March 17, 2017 | Phase 1 |
NCT00568295 | Johnson & Johnson Consumer and Personal Products Worldwide |
Osteoarthritis of the Knee
|
October 1999 | Phase 3 |
NCT04931693 | Kasr El Aini Hospital |
Complete Heart Block
|
December 20, 2021 | Phase 4 |
NCT01366313 | Procare Riaya Hospital |
Postoperative Pain
|
September 2007 | Not Applicable |
NCT03122561 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
Diurnal Variation of Paracetamol Excretion
|
November 3, 2016 | Not Applicable |
NCT02750696 | Federal University of Rio Grande do Sul|Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. |
Periapical Abscess
|
April 2013 | Not Applicable |
NCT03063658 | Ankara University |
Acute Pain|Postoperative Pain
|
February 1, 2017 | Phase 4 |
NCT00378547 | Glostrup University Hospital, Copenhagen |
Pain, Postoperative
|
January 2006 | Phase 4 |
NCT03224637 | Assiut University |
Osteo Arthritis Knee|Pain, Chronic
|
July 2014 | Not Applicable |
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years |
* The compound is unstable in solutions, freshly prepared is recommended.
DMSO : 250 mg/mL ( 1653.88 mM ; Need ultrasonic)
H 2 O : 10 mg/mL ( 66.16 mM ; Need ultrasonic)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 6.6155 mL | 33.0775 mL | 66.1551 mL |
5 mM | 1.3231 mL | 6.6155 mL | 13.2310 mL |
10 mM | 0.6616 mL | 3.3078 mL | 6.6155 mL |
Add each solvent one by one: 0.5% CMC-Na /saline water
Solubility: 10 mg/mL (66.16 mM); Suspended solution; Need ultrasonic
Add each solvent one by one: saline >> 0.5% Tween-80
Solubility: 10 mg/mL (66.16 mM); Clear solution; Need ultrasonic
Add each solvent one by one: PBS
Solubility: 6.67 mg/mL (44.13 mM); Clear solution; Need ultrasonic
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (13.76 mM); Clear solution
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (13.76 mM); Clear solution