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[CAS NO. 103773-62-2] Ganoderic acid C2
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N1517 |
| Brand: | MCE |
| CAS: | 103773-62-2 |
Overview
| MDL | MFCD04039842 |
|---|---|
| Molecular Weight | 518.68 |
| Molecular Formula | C30H46O7 |
| SMILES | CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H] |
Summary
Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum . Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC 50 of 3.8 µM [1] [2] .
IC50 & Target
IC50: 3.8 µM (RLAR) [2]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL ( 96.40 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9280 mL | 9.6399 mL | 19.2797 mL |
| 5 mM | 0.3856 mL | 1.9280 mL | 3.8559 mL |
| 10 mM | 0.1928 mL | 0.9640 mL | 1.9280 mL |
References
- [1] Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73.
- [2] Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3.
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