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[CAS NO. 104987-11-3] Tacrolimus

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Catalog:	HY-13756
Brand:	MCE
CAS:	104987-11-3

Overview

MDL	MFCD00869853
Molecular Weight	804.02
Molecular Formula	C44H69NO12
SMILES	O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O

For research use only. We do not sell to patients.

45 Publications Citing Use of MCE

[1]J Extracell Vesicles. 2019 Dec 27;9(1):1709262.
[2]Nano Lett. 2019 Jan 9;19(1):124-134.
[3]Biomaterials. 2021, 120757.
[4]Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2009539118.
[5]Cell Syst. 2018 Apr 25;6(4):424-443.e7.
[6]Theranostics. 2022 Jan 16;12(4):1621-1638.
[7]Theranostics. 2021 Mar 5;11(10):5045-5060.
[8]Theranostics. 2020 May 16;10(14):6483-6499.
[9]Theranostics. 2018 Jan 1;8(4):878-893.
[10]Nano Res. 11, 6086-6101(2018).
[11]J Colloid Interface Sci. 5 October 2022.
[12]Cell Rep. 2021 Jul 20;36(3):109404.
[13]Cell Rep. 2021 Apr 6;35(1):108959.
[14]Br J Pharmacol. 2022 Jan 20.
[15]J Control Release. 2020 Dec 10;328:237-250.
[16]Am J Transplant. 2022.
[17]NPJ Regen Med. 2022 Sep 2;7(1):43.
[18]Cell Biol Toxicol. 2022 Jun;38(3):487-504.
[19]Biomater Sci. 2020 Oct 7;8(19):5282-5292.
[20]Pharmacol Res. 2021, 105382.
[21]FASEB J. 2023 Feb;37(2):e22749.
[22]Drug Deliv. 2021 Dec;28(1):1759-1768.
[23]Int J Pharm. 2019 Dec 13;575:118951.
[24]J Cell Sci. 2019 May 20;132(10):jcs227777.
[25]Int J Mol Sci. 2022 Aug 19;23(16):9376.
[26]Cell Commun Signal. 2021 Oct 11;19(1):103.
[27]Acs Biomater Sci Eng. 2022 Oct 10.
[28]J Neurochem. 2022 Oct 21.
[29]Mediat Inflamm. 2019 Dec 17;2019:4176974.
[30]Skelet Muscle. 2020 Apr 22;10(1):10.
[31]Toxins (Basel). 2019 Jun 18;11(6):349.
[32]Invest Ophthalmol Vis Sci. 2023 Jan 3;64(1):19.
[33]Biochim Biophys Acta Gen Subj. 2022 Jun;1866(6):130133.
[34]Brain Res. 2019 May 15;1711:68-76.
[35]Acta Trop. 2020 Dec;212:105708.
[36]BMC Pharmacol Toxicol. 2022 Nov 28;23(1):87.
[37]Transpl Immunol. 2021 Jun 30;101434.
[38]Animal Model Exp Med. 2022 Sep 21.
[39]Patent. US20220087984A1.
[40]Research Square Preprint. 2020 Dec.
[41]Dis Model Mech. 2019 Jan 28;12(1). pii: dmm036830.
[42]Patent. US20180263995A1.
[43]Exp Hematol Oncol. 2016 Jul 29;5:22.
[44]Am J Digest Dis. 2015;2(2):95-99.
[45]Int J Physiol Pathophysiol Pharmacol. 2015 Mar 20;7(1):54-60.

Summary

Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties ^[1] .

IC50 & Target

Macrolide

In Vitro

Tacrolimus (FK506) inhibits calcium-dependent events, such as IL-2 gene transcription, NO synthase activation, cell degranulation, and apoptosis. Tacrolimus also potentiates the actions of glucocorticoids and progesterone by binding to FKBPs contained within the hormone receptor complex, preventing degradation. The agent may enhance expression of the TGFβ-1 gene in a fashion analogous to that demonstrated for CsA. T cell proliferation in response to ligation of the T cell receptor is inhibited by Tacrolimus ^[1] . Treatment with a low concentration of Tacrolimus (FK506,10 μg/L) does not significantly affect the proliferation of MH3924A cells (P=0.135). Upon treatment with higher concentrations of Tacrolimus (100-1,000 μg/L), the proliferation of MH3924A cells is significantly enhanced (P<0.01). Treatment with AMD3100 at any concentration (10, 50 or 100 μg/L), has no obvious effect on MH3924A cell proliferation (P>0.05). However, when different concentrations of AMD3100 are combined with 100 μg/L Tacrolimus, the in vitro proliferation of MH3924A cells is increased (P<0.01) ^[3] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The therapeutic effect of Tacrolimus is investigated on progression and perpetuation of colitis by administering Tacrolimus to Dextran sulfate sodium (DSS)-treated mice from Days 10 to 16 or to 23. At Days 17 and 24, colon length is significantly shortened, and colon weight is significantly higher in DSS-treated control animals than in normal animals. In addition, colon weight per unit length in the control group is more than twice that in the normal group. While both 7 and 14 d treatment with Tacrolimus significantly suppresses increases in colon weight per unit length in DSS-treated animals compared with the control group, this treatment does not actually restore the colon shortening. In addition, this inhibitory effect of Tacrolimus on increases in colon weight per unit length is more pronounced with 14-d than 7-d treatment, as shown by the inhibitory percentages (59% vs. 28%) ^[4] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00177138	University of Minnesota\|Bayer\|Gruessner, Rainer, MD	Diabetes Mellitus	July 2004	Phase 4
NCT01856257	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation	Primary Renal Allograft Candidate\|Kidney Transplantation	July 2013	Phase 2
NCT00938860	Novartis Pharmaceuticals\|Novartis	Hepatitis C\|Liver Transplantation	September 2009	Phase 4
NCT01619761	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|DS Stage II Plasma Cell Myeloma\|DS Stage III Plasma Cell Myeloma\|High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements\|ISS Stage II Plasma Cell Myeloma\|ISS Stage III Plasma Cell Myeloma\|Myelodysplastic Syndrome\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Hodgkin Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Acute Lymphoblastic Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hodgkin Lymphoma\|Refractory Non-Hodgkin Lymphoma\|Refractory Small Lymphocytic Lymphoma\|Secondary Acute Myeloid Leukemia\|Therapy-Related Acute Myeloid Leukemia\|Therapy-Related Myelodysplastic Syndrome	May 3, 2013	Phase 1
NCT01511003	Astellas Pharma Inc\|Astellas Pharma Korea, Inc.	Rheumatoid Arthritis	December 5, 2011	Phase 4
NCT00296348	Astellas Pharma Inc	Kidney Transplantation	November 2005	Phase 3
NCT01828879	Janssen-Cilag Ltd.,Thailand	Dermatitis, Atopic	November 2007	Phase 4
NCT00304720	Colorado Blood Cancer Institute	Multiple Myeloma\|Lymphoma\|Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	March 2004	Phase 2
NCT01625377	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	December 2012	Phase 3
NCT03781414	Novartis Pharmaceuticals\|Novartis	Liver Transplant Rejection	October 7, 2019	Phase 2
NCT00666159	Astellas Pharma Inc	Dermatitis, Atopic	December 2002	Phase 4
NCT02766465	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|Dana-Farber Cancer Institute\|National Marrow Donor Program\|Emory University	Sickle Cell Disease	November 2016	Phase 2
NCT01220531	Enzyvant Therapeutics GmBH\|National Institutes of Health (NIH)\|National Institute of Allergy and Infectious Diseases (NIAID)\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	Complete DiGeorge Anomaly\|DiGeorge Syndrome\|DiGeorge Anomaly\|Complete DiGeorge Syndrome
NCT00810602	Pavan Reddy, MD\|University of Michigan Rogel Cancer Center	Hematologic Malignancies\|Graft vs Host Disease	January 2009	Phase 1\|Phase 2
NCT01927120	H. Lee Moffitt Cancer Center and Research Institute	Graft-Versus-Host-Disease	March 25, 2014	Phase 2
NCT02167958	Rafic Farah, MD\|University of Pittsburgh	Leukemia\|MDS\|Myelofibrosis\|Lymphoma	February 11, 2015	Phase 1
NCT02652468	University of Wisconsin, Madison	Lymphoma	March 10, 2016	Not Applicable
NCT00144677	Dana-Farber Cancer Institute	Acute Myelogenous Leukemia\|Graft Versus Host Disease\|Acute Lymphoblastic Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndromes\|Non-Hodgkin´s Lymphoma\|Hodgkin´s Disease	November 2003	Phase 2
NCT03222687	Shandong University	Henoch-Schönlein Purpura Nephritis	September 1, 2015	Phase 4
NCT00552201	Centre Hospitalier Universitaire, Amiens\|Roche Pharma AG\|Astellas Pharma Inc	Kidney Transplantation	April 2006	Phase 4
NCT00104975	Yale University\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	February 2005	Phase 1
NCT02960646	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Aplastic Anemia\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Lymphoblastic Lymphoma\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Plasma Cell Myeloma\|Recurrent Chronic Lymphocytic Leukemia+Small Lymphocytic Lymphoma\|Recurrent Hodgkin Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Therapy-Related Myelodysplastic Syndrome	January 18, 2017	Phase 1
NCT02188719	National Institute of Allergy and Infectious Diseases (NIAID)\|Rho Federal Systems Division, Inc.	Liver Transplantation	December 17, 2014	Phase 1
NCT05152628	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Liver Transplantation\|Kidney Transplantation	January 11, 2022	Phase 4
NCT00290069	Sociedad Andaluza de Trasplantes de Organos y Tejidos	Kidney Diseases\|Graft Rejection		Phase 4
NCT04048161	The Children´s Hospital of Zhejiang University School of Medicine\|Children´s Hospital of Fudan University\|Peking University First Hospital\|First Affiliated Hospital of Zhongshan Medical University\|Nanjing Children´s Hospital\|Chengdu Women and Children´s Center Hospital\|Tongji Hospital\|Second Xiangya Hospital of Central South University\|Children´s Hospital of Chongqing Medical University\|Children´s Hospital Of Soochow University\|Henan Provincial People´s Hospital\|Shandong Provincial Hospital	Nephrotic Syndrome in Children	November 12, 2019	Phase 4
NCT00555048	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	September 2007	Phase 1\|Phase 2
NCT00691262	Astellas Pharma Inc	Dermatitis, Atopic	October 2003	Phase 3
NCT02158052	Massachusetts General Hospital	Multiple Myeloma\|Amyloidosis	February 2015	Not Applicable
NCT03358082	Sohag University	Vitiligo\|Tacrolimus	October 1, 2017	Phase 1\|Phase 2
NCT00302549	Nanjing University School of Medicine\|Sun Yat-sen University	Lupus Nephritis	May 2004	Not Applicable
NCT03674411	Masonic Cancer Center, University of Minnesota	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Biphenotypic+Undifferentiated Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplasia\|Relapsed Large Cell Lymphoma\|Mantle Cell Lymphoma\|Hodgkin Lymphoma\|Burkitt Lymphoma\|Relapsed T-Cell Lymphoma\|Lymphoplasmacytic Lymphoma	January 2, 2019	Phase 2
NCT03918265	Peking Union Medical College Hospital	Autoimmune Hemolytic Anemia\|Pure Red Cell Aplasia\|Evans Syndrome	May 4, 2019	Phase 4
NCT02457221	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Lupus Nephritis	March 10, 2015	Phase 3
NCT01132027	Dr. Reddy´s Laboratories Limited	Healthy	January 2008	Phase 1
NCT00003572	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	August 1998	Phase 2
NCT04776850	M.D. Anderson Cancer Center	Beta Thalassemia Major\|Sickle Beta 0 Thalassemia\|Sickle Beta Plus Thalassemia\|Sickle Beta Thalassemia\|Sickle Cell Disease\|Sickle Cell-SS Disease	December 29, 2020	Early Phase 1
NCT00709592	Virginia Commonwealth University\|Genzyme, a Sanofi Company	Non-Hodgkin´s Lymphoma\|Leukemia\|Multiple Myeloma\|Acute Myeloid Leukemia\|Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndrome	July 21, 2008	Phase 2
NCT00611351	Lori Maness Harris, MD\|National Cancer Institute (NCI)\|University of Nebraska	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Secondary Myelofibrosis	June 2005	Phase 2
NCT04224350	Chong Kun Dang Pharmaceutical	Kidney Transplant	December 17, 2018	Phase 4
NCT01350245	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Acute Myeloid Leukemia\|Myelodysplastic Syndromes\|Biphenotypic Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Chronic Lymphocytic Leukemia\|Plasma Cell Neoplasms\|Lymphoma\|Hodgkin´s Disease\|Aplastic Anemia	July 2010	Phase 2
NCT00689832	Astellas Pharma Inc	Dermatitis, Atopic	February 2004	Phase 4
NCT02528877	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Myeloid Leukemia in Remission\|Primary Myelofibrosis\|Primary Myelofibrosis, Prefibrotic Stage\|Secondary Acute Myeloid Leukemia\|Secondary Myelofibrosis	November 2015	Phase 1
NCT01150097	Novartis Pharmaceuticals\|Novartis	Liver Transplant Recipient	March 31, 2010	Phase 3
NCT01544842	University of Oulu\|Kuopio University Hospital	Oral Lichen Planus	August 2004	Not Applicable
NCT01388387	Rennes University Hospital	Hepatic Transplantation	February 22, 2012	Not Applicable
NCT02159651	Astellas Pharma Inc	Interstitial Pneumonia Associated With Polymyositis+Dermatomyositis	April 1, 2014
NCT00121186	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	July 2005	Phase 2
NCT00622895	Fred Hutchinson Cancer Center\|National Institute of Allergy and Infectious Diseases (NIAID)	Systemic Scleroderma\|Severe Systemic Sclerosis	September 1, 2006	Phase 1\|Phase 2
NCT00273871	Wyeth is now a wholly owned subsidiary of Pfizer	Graft Rejection\|Kidney Failure\|Kidney Transplantation	January 2002	Phase 3
NCT00117702	Technische Universität Dresden	Graft vs Host Disease	October 2005	Phase 2\|Phase 3
NCT01055964	Seoul National University Hospital	Pharmacokinetics\|Tacrolimus	September 2008	Phase 3
NCT04633733	Hanlim Pharm. Co., Ltd.	Healthy Male Volunteers	August 22, 2020	Phase 1
NCT00133887	Hospices Civils de Lyon	Skin Cancer\|Kidney Transplantation	April 2004	Phase 3
NCT00189722	Astellas Pharma Inc\|Astellas Pharma Europe B.V.	Asthma, Bronchial\|Bronchial Asthma		Phase 2
NCT01955187	Hospital Universitario 12 de Octubre\|Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz\|Hospital Universitario Fundación Alcorcón\|Fundación para la Investigación Biomédica Hospital Universitario 12 de Octubre\|Biobanco REDinREN\|ERA-EDTA\|REDinREN\|Spanish Society of Nephrology\|Fundación de Investigación Biomédica - Hospital Universitario de La Princesa\|University Hospital, Aachen	MEMBRANOUS NEPHROPATHY	January 2014	Phase 3
NCT01289301	Hannover Medical School	Disorder Related to Renal Transplantation\|Immunosuppression Related Infectious Disease\|Virus Diseases	October 2011	Phase 4
NCT01729494	University of Cincinnati	Renal Transplantation	September 2012	Phase 4
NCT03663335	Novartis Pharmaceuticals\|Novartis	Kidney Transplant Rejection	November 28, 2018	Phase 2
NCT04646356	Unity Health Toronto\|United States Department of Defense	Hereditary Hemorrhagic Telangiectasia\|Epistaxis Nosebleed	October 20, 2020	Phase 2
NCT03970096	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Undifferentiated Leukemia\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Lymphoblastic Lymphoma\|Mixed Phenotype Acute Leukemia\|Acute Leukemia\|Hematopoietic and Lymphoid Cell Neoplasm	November 19, 2019	Phase 2
NCT00317681	Heinrich-Heine University, Duesseldorf	Cutaneous Lupus Erythematosus	August 2005	Phase 2
NCT00545402	Hoffmann-La Roche	Liver Transplantation	November 2007	Phase 4
NCT00293891	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Psoriasis		Phase 3
NCT03794492	Chong Kun Dang Pharmaceutical	Kidney Transplant	March 31, 2018	Phase 4
NCT03066466	Loyola University	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2019	Phase 3
NCT01224028	Astellas Pharma Inc\|Astellas Pharma Korea, Inc.	IgA Nephropathy	November 2010	Phase 2
NCT00643071	Astellas Pharma Inc	Ulcerative Colitis	September 2006	Phase 3
NCT01303965	Sherif S. Farag\|Celgene Corporation\|Indiana University	Multiple Myeloma	February 7, 2011	Phase 1\|Phase 2
NCT00064701	Astellas Pharma Inc	Kidney Transplantation	June 2003	Phase 3
NCT02880293	Memorial Sloan Kettering Cancer Center	Hematologic Malignancy	August 23, 2016	Not Applicable
NCT00518271	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplantation	April 2000	Phase 2
NCT03511560	Columbia University\|Veloxis Pharmaceuticals	Renal Transplant Rejection\|Kidney Transplant Failure and Rejection	July 26, 2018	Phase 4
NCT03734601	Stanford University	Acute Myeloid Leukemia\|Myelodysplastic Syndromes\|Myeloproliferative Disorder\|Chronic Lymphocytic Leukemia\|B-cell Lymphoma\|T-cell Lymphoma\|Non Hodgkin Lymphoma\|Hodgkin Lymphoma\|Chronic Myelomonocytic Leukemia	November 5, 2018	Phase 2
NCT03464435	Zhongshan Ophthalmic Center, Sun Yat-sen University	Vernal Keratoconjunctivitis	November 1, 2016	Phase 4
NCT01788501	Seoul National University Hospital	Graft vs Host Disease	November 2011	Phase 2\|Phase 3
NCT02080195	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|Maryland Stem Cell Research Fund	Lupus Erythematosus\|Graft-versus-host Disease	September 13, 2016	Phase 1\|Phase 2
NCT00189748	Astellas Pharma Inc	Bone Marrow Transplantation\|Graft Versus Host Disease\|Graft-Versus-Host Disease\|Graft-Vs-Host Disease	August 2004	Phase 2
NCT01678937	Northwestern University\|Northwestern Memorial Hospital	Liver Transplant Rejection\|Immunosuppression	September 2007
NCT01056614	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Phase Chronic Myelogenous Leukemia\|de Novo Myelodysplastic Syndromes\|Hematopoietic+Lymphoid Cancer\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Relapsing Chronic Myelogenous Leukemia	September 2004	Phase 2
NCT00885820	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Kidney Transplantation	September 2001	Phase 4
NCT05622318	Medical College of Wisconsin	Graft-versus-host Disease	January 15, 2023	Phase 2
NCT02061800	Diane George\|Columbia University	Chronic Myeloid Leukemia (CML)\|Acute Myelogenous Leukemia (AML)\|Myelodysplastic Syndrome (MDS)\|Juvenile Myelomonocytic Leukemia (JMML)\|Acute Lymphoblastic Leukemia (ALL)\|Lymphoma (Hodgkin´s and Non-Hodgkin´s)	June 3, 2013	Phase 1\|Phase 2
NCT02805842	Rabin Medical Center\|Astellas Pharma Inc\|Teva Pharma	Medication Adherence	August 2016	Phase 3
NCT00608894	Veloxis Pharmaceuticals	Autoimmune Hepatitis	December 2007	Phase 2
NCT00510913	Astellas Pharma Inc	Graft Rejection\|Kidney Transplantation	February 1999	Phase 4
NCT00347048	Astellas Pharma Inc	Ulcerative Colitis	September 2006	Phase 3
NCT00002792	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic+Myeloproliferative Diseases	June 1996	Phase 2
NCT03413722	University of Kansas Medical Center\|Novartis Pharmaceuticals	End Stage Renal Disease	February 1, 2018
NCT00535691	Astellas Pharma Inc	Dermatitis, Atopic	April 2003	Phase 2
NCT00157014	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Heart Diseases\|Heart Transplantation	May 10, 2004	Phase 3
NCT03540472	Peking Union Medical College Hospital	Pure Red Cell Aplasia	June 10, 2018	Phase 4
NCT01518153	M.D. Anderson Cancer Center	Leukemia\|Lymphoma\|Myeloma\|Myeloproliferative Diseases	February 2012	Phase 2
NCT01871441	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Malignant Neoplasm	May 17, 2013	Phase 2
NCT00268515	National Heart, Lung, and Blood Institute (NHLBI)	Lung Diseases	April 1998	Phase 2
NCT01640743	IRCCS Policlinico S. Matteo	Kidney Transplantation	March 2010	Not Applicable
NCT00332839	Novartis Pharmaceuticals\|Novartis	Renal Transplantation	November 2005	Phase 4
NCT00106392	Astellas Pharma Inc	Erectile Dysfunction\|Prostate Cancer	February 2005	Phase 4
NCT00105001	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndrome\|Refractory Chronic Lymphocytic Leukemia\|Refractory Plasma Cell Myeloma\|Waldenstrom Macroglobulinemia\|Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL\|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11\|Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1\|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Lymphoma\|Childhood Myelodysplastic Syndrome\|Stage II Contiguous Adult Burkitt Lymphoma\|Stage II Contiguous Adult Diffuse Large Cell Lymphoma\|Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma\|Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma\|Stage II Adult Contiguous Immunoblastic Lymphoma\|Stage II Contiguous Adult Lymphoblastic Lymphoma\|Stage II Grade 1 Contiguous Follicular Lymphoma\|Stage II Grade 2 Contiguous Follicular Lymphoma\|Stage II Grade 3 Contiguous Follicular Lymphoma\|Stage II Contiguous Mantle Cell Lymphoma\|Stage II Non-Contiguous Adult Burkitt Lymphoma\|Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma\|Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma\|Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma\|Stage II Adult Non-Contiguous Immunoblastic Lymphoma\|Stage II Non-Contiguous Adult Lymphoblastic Lymphoma\|Stage II Grade 1 Non-Contiguous Follicular Lymphoma\|Stage II Grade 2 Non-Contiguous Follicular Lymphoma\|Stage II Grade 3 Non-Contiguous Follicular Lymphoma\|Stage II Non-Contiguous Mantle Cell Lymphoma\|Stage II Small Lymphocytic Lymphoma\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Burkitt Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Recurrent Childhood Hodgkin Lymphoma\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Secondary Myelodysplastic Syndrome\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Immunoblastic Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Childhood Anaplastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Lymphoblastic Lymphoma\|Stage I Childhood Burkitt Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Small Lymphocytic Lymphoma\|Stage II Childhood Anaplastic Large Cell Lymphoma\|Stage II Childhood Lymphoblastic Lymphoma\|Stage II Childhood Burkitt Lymphoma\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Immunoblastic Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Childhood Anaplastic Large Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Lymphoblastic Lymphoma\|Stage III Childhood Burkitt Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Immunoblastic Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Childhood Burkitt Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma	November 2004	Phase 2
NCT00446264	University Hospital, Lille\|Institut National de la Santé Et de la Recherche Médicale, France	Type 1 Diabetes\|Hypoglycemia\|Metabolic Diseases	May 2003	Phase 2
NCT01649427	Novartis Pharmaceuticals\|Novartis	Pharmacokinetics Study in de Novo Kidney Transplantation	October 17, 2012	Phase 4
NCT02274662	Enzyvant Therapeutics GmBH	Poor Thymic Function\|Immunodeficiency\|Athymia\|Immunoreconstitution\|Thymus Transplantation\|Low T Cell Numbers
NCT04258423	Indiana University	Kidney Failure	December 19, 2019	Phase 3
NCT05532111	RenJi Hospital	Efficacy and Safety	September 1, 2022	Not Applicable
NCT00480896	Astellas Pharma Inc	Dermatitis, Atopic	June 2004	Phase 3
NCT00043979	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Sarcoma	September 19, 2002	Phase 2
NCT03095547	F2G Biotech GmbH\|Bio-Kinetic Europe, Ltd.	Invasive Aspergillosis	May 2017	Phase 1
NCT03535051	Kasr El Aini Hospital	Stable Vitiligo	January 1, 2015	Not Applicable
NCT03388008	Washington University School of Medicine\|National Heart, Lung, and Blood Institute (NHLBI)\|Bristol-Myers Squibb	Lung Transplant Rejection\|Antibody-mediated Rejection	December 17, 2019	Phase 2
NCT00007787	National Institute of Allergy and Infectious Diseases (NIAID)	Kidney Transplantation\|Chronic Allograft Nephropathy	April 2000	Not Applicable
NCT02438982	Nilratan Sircar Medical College	Nephrotic Syndrome	May 8, 2015	Phase 3
NCT01564095	Ludwig-Maximilians - University of Munich	Terminal Liver Disease\|Ischemia Reperfusion Injury\|Graft Dysfunction\|Graft Failure\|Poor Graft Quality	October 2011	Phase 2\|Phase 3
NCT00489203	Fred Hutchinson Cancer Center	Hematopoietic+Lymphoid Cancer\|Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Atypical Chronic Myeloid Leukemia\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Eosinophilic Leukemia\|Chronic Myelomonocytic Leukemia\|Chronic Neutrophilic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Extramedullary Plasmacytoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Isolated Plasmacytoma of Bone\|Juvenile Myelomonocytic Leukemia\|Meningeal Chronic Myelogenous Leukemia\|Myelodysplastic+Myeloproliferative Disease, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Childhood Hodgkin Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Multiple Myeloma\|Stage I Mycosis Fungoides+Sezary Syndrome\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult Hodgkin Lymphoma\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Multiple Myeloma\|Stage II Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Small Lymphocytic Lymphoma	April 2007	Phase 2
NCT04063865	Indiana University	Kidney Failure	May 9, 2019	Phase 3
NCT01008462	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	B-Cell Prolymphocytic Leukemia\|Hypodiploidy\|Loss of Chromosome 17p\|Plasma Cell Leukemia\|Progression of Multiple Myeloma or Plasma Cell Leukemia\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Non-Hodgkin Lymphoma\|Recurrent Childhood Hodgkin Lymphoma\|Recurrent Childhood Non-Hodgkin Lymphoma\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Non-Hodgkin Lymphoma\|Refractory Plasma Cell Myeloma\|Refractory Small Lymphocytic Lymphoma\|t(14;16)\|t(4;14)\|T-Cell Prolymphocytic Leukemia\|Waldenstrom Macroglobulinemia	March 18, 2010	Phase 2
NCT00295997	University of California, San Francisco\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	May 2005	Not Applicable
NCT00513474	Massachusetts General Hospital	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	January 2008	Phase 1
NCT01312064	National Taiwan University Hospital	Renal Insufficiency	April 2011	Phase 4
NCT00378326	Rockefeller University	Paraneoplastic Syndromes	April 2006	Not Applicable
NCT02587052	Vastra Gotaland Region	Renal Transplantation	October 2015
NCT00275509	Johns Hopkins University	Kidney Failure, Chronic	January 2007	Phase 3
NCT01080456	Panacea Biotec Ltd	Healthy Volunteers	September 2007	Not Applicable
NCT02341274	Indiana University\|Food and Drug Administration (FDA)	Bioequivalence	November 11, 2016	Phase 1
NCT01446484	Pirogov Russian National Research Medical University\|Russian Academy of Medical Sciences	End-Stage Renal Disease\|Kidney Failure	October 2011	Phase 1\|Phase 2
NCT00434811	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Type 1 Diabetes Mellitus	October 2006	Phase 3
NCT00982072	Imperial College Healthcare NHS Trust	Minimal Change Disease	December 2009	Phase 4
NCT03289650	Lorenzo Gallon\|Northwestern University	End Stage Renal Disease\|Rejection of Renal Transplant	September 5, 2017	Phase 3
NCT03703154	University of Kansas Medical Center\|Veloxis Pharmaceuticals	End Stage Renal Disease	October 25, 2018
NCT02808065	Seoul National University Hospital\|Ministry of Food and Drug Safety, Korea	Kidney Transplantation	May 2016
NCT01068054	Siriraj Hospital	Keratoconjunctivitis, Vernal	June 2003	Phase 2\|Phase 3
NCT00456235	University Hospital, Limoges	Liver Transplantation	September 2006	Phase 4
NCT01256398	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	December 14, 2010	Phase 2
NCT00556933	R. Brian Stevens, MD\|Genzyme, a Sanofi Company\|University of Nebraska	End-stage Renal Disease	April 2004	Phase 4
NCT02744378	University of Peradeniya	Oral Lichen Planus	June 2014	Phase 2
NCT01534143	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Refractory Multiple Myeloma\|Stage I Multiple Myeloma\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma	February 2012	Phase 2
NCT01629511	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Allogeneic Hematopoietic Stem Cell Transplantation Recipient\|Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Richter Syndrome	November 21, 2012	Phase 1\|Phase 2
NCT01160276	Assistance Publique - Hôpitaux de Paris\|Institut National de la Santé Et de la Recherche Médicale, France	Renal Replacement Therapies	May 2010	Phase 1
NCT00534508	Astellas Pharma Inc	Dermatitis, Atopic	December 2000	Phase 2
NCT03032783	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematopoietic and Lymphoid Cell Neoplasm	January 31, 2017	Phase 2
NCT01810588	Weill Medical College of Cornell University	Hematologic Malignancies	October 16, 2012	Phase 2
NCT02447055	Washington University School of Medicine	Multiple Myeloma\|Myeloma-Multiple	December 2015	Early Phase 1
NCT02411604	Veloxis Pharmaceuticals	Renal Failure
NCT00296309	Astellas Pharma Inc\|Astellas Pharma Europe B.V.	Kidney Transplantation	October 2004	Phase 3
NCT02821026	University of Alberta	Type 1 Diabetes	May 2016	Phase 1\|Phase 2
NCT03882164	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Liver Transplant; Complications\|Immunosuppression\|Transplant Failure\|Transplant; Complication, Rejection	February 21, 2019
NCT02154854	University Hospital, Tours\|Astellas Pharma Inc	De Novo Transplant Disease	July 2013	Phase 4
NCT01680861	Gaetano Ciancio\|University of Miami	Transplant; Failure, Kidney	November 2012	Phase 3
NCT00147381	Dr. Claudia Bösmüller\|Astellas Pharma GmbH\|Medical University Innsbruck	Kidney Transplantation	January 2004	Phase 3
NCT00469131	Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan\|Kyoto University	Hepatitis C\|Liver Cirrhosis	September 2003	Phase 3
NCT02152345	Columbia University	Implant or Graft; Rejection	June 2014	Phase 4
NCT03715387	University of British Columbia	Edema Face	October 10, 2018	Phase 2\|Phase 3
NCT01207297	Zhejiang University	SLE\|Lupus Nephritis\|Renal Insufficiency\|End-stage Renal Disease	March 2003	Phase 1
NCT00686855	Brigham and Women´s Hospital\|Dana-Farber Cancer Institute\|Boston Children´s Hospital\|Beth Israel Deaconess Medical Center\|Massachusetts General Hospital	Oral Chronic Graft-versus-host Disease	August 2008	Phase 2
NCT04339101	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Leukemia\|Hematologic and Lymphocytic Disorder\|Myelodysplastic Syndrome\|Primary Myelofibrosis\|Secondary Myelofibrosis	November 11, 2020	Phase 2
NCT00078559	University of Wisconsin, Madison\|Immune Tolerance Network (ITN)	Kidney Transplantation\|Kidney Disease	November 2003	Phase 1\|Phase 2
NCT02866682	University of California, Los Angeles\|Food and Drug Administration (FDA)	Renal Transplant Rejection	March 1, 2018	Phase 4
NCT00995059	Mayo Clinic	Multiple Myeloma\|Refractory Multiple Myeloma		Phase 1\|Phase 2
NCT03605927	H. Lee Moffitt Cancer Center and Research Institute\|Bristol-Myers Squibb	Graft-versus-host-disease\|GVHD\|GVHD, Acute	February 15, 2019	Phase 1
NCT01388517	Universidad Autonoma de San Luis Potosí\|Hospital Central Dr. Ignacio Morones Prieto	Pityriasis Alba	January 2008	Phase 4
NCT04859946	M.D. Anderson Cancer Center\|Incyte Corporation	Hematologic and Lymphocytic Disorder	January 11, 2022	Phase 1
NCT00301951	University of California, San Francisco\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	September 2004	Phase 1
NCT01746680	Chong Kun Dang Pharmaceutical	Rheumatoid Arthritis	August 2012	Phase 4
NCT03096782	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Leukemia\|Acute Lymphoblastic Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Chemotherapy-Related Leukemia\|Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Hodgkin Lymphoma\|Langerhans Cell Histiocytosis\|Minimal Residual Disease\|Myelodysplastic Syndrome\|Myelodysplastic Syndrome With Excess Blasts\|Non-Hodgkin Lymphoma\|Recurrent Hodgkin Lymphoma\|Refractory Acute Lymphoblastic Leukemia\|Refractory Myelodysplastic Syndrome\|Small Lymphocytic Lymphoma\|Therapy-Related Myelodysplastic Syndrome	October 13, 2017	Phase 2
NCT04154735	Northwestern University	Crohn´s Disease	November 2019	Phase 2
NCT01889758	University of Cincinnati\|University of Colorado, Denver\|Children´s Hospital Medical Center, Cincinnati	Kidney Transplant Recipients\|Liver Transplant Recipients	June 2013	Phase 4
NCT00296296	Stanford University	Kidney Transplant\|Diabetes Mellitus, Type 2\|Diabetic Nephropathy	June 2005	Phase 4
NCT00538265	University Hospital, Toulouse	Liver Transplantation	May 2005	Phase 4
NCT00293917	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Psoriasis	January 2006	Phase 3
NCT05153915	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Liver Transplantation\|Kidney Transplantation	December 30, 2021	Phase 4
NCT01047072	Fred Hutchinson Cancer Research Center+University of Washington Cancer Consortium\|National Cancer Institute (NCI)\|Fred Hutchinson Cancer Center	Systemic Scleroderma		Phase 2
NCT01560572	University Medical Center Groningen\|Leiden University Medical Center\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Renal Insufficiency\|Kidney Transplantation	April 2011	Phase 4
NCT00106639	Pfizer	Kidney Transplantation	May 2005	Phase 2
NCT03549663	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	Idiopathic Membranous Nephropathy	July 4, 2018	Not Applicable
NCT00525681	University of Oslo School of Pharmacy	Renal Transplantation	September 2007	Phase 4
NCT04205240	Srinivas Devarakonda\|Ohio State University Comprehensive Cancer Center	Recurrent Plasma Cell Myeloma	May 27, 2020	Phase 2
NCT01491958	Ohio State University Comprehensive Cancer Center	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2011	Phase 2
NCT02558452	Klemens Budde\|Dr. med. univ. L. J. Lehner\|Charite University, Berlin, Germany\|ERA-EDTA\|DESCARTES Working Group On Transplantation\|European Kidney Transplant Association (EKITA)	Graft Failure\|Death\|Acute Rejection of Renal Transplant\|Infections\|Bone Disease\|Post Transplant Diabetes Mellitus\|Quality of Life\|HLA Antibody Production\|Cardiovascular Risk Factors\|Non-HLA Antibody Production	December 2016
NCT02456025	The Eye Center and The Eye Foundation for Research in Ophthalmology	Vernal Keratoconjunctivitis	April 2013	Phase 4
NCT00056966	Baylor College of Medicine\|The Methodist Hospital Research Institute\|Center for Cell and Gene Therapy, Baylor College of Medicine	Hematologic Malignancy	November 2002	Phase 1\|Phase 2
NCT02867800	Monica Bhatia\|Columbia University	Sickle Cell Disease\|Graft Versus Host Disease	July 2016	Phase 1
NCT05501574	TFF Pharmaceuticals, Inc.	Lung Transplant Rejection	November 1, 2022	Phase 2
NCT00468403	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Islet Transplantation Consortium	Type 1 Diabetes Mellitus	October 2008	Phase 2
NCT01760655	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Juvenile Myelomonocytic Leukemia\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Polycythemia Vera\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Acute Myeloid Leukemia\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Waldenström Macroglobulinemia	December 24, 2012	Phase 2
NCT04263519	Massachusetts General Hospital	Alzheimer Disease\|Mild Cognitive Impairment	December 1, 2021	Phase 2
NCT00693524	Astellas Pharma Inc	Liver Transplantation	November 2002	Phase 2
NCT01951885	Case Comprehensive Cancer Center	Chronic Myelogenous Leukemia\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Biphenotypic Leukemia\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Non-Hodgkin Lymphoma\|Hodgkins Disease\|Chronic Lymphocytic Leukemia\|Multiple Myeloma	July 7, 2014	Phase 3
NCT03199664	South Valley University	Vitiligo	September 1, 2017	Phase 4
NCT02833805	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Severe Aplastic Anemia\|Aplastic Anemia\|Bone Marrow Failure\|Immunosuppression	September 2016	Phase 2
NCT03099122	Sanofi	End-stage Renal Disease	August 16, 2017	Phase 4
NCT03737708	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Rheumatoid Arthritis (RA)	February 13, 2019	Phase 4
NCT02064777	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	Pediatric Liver Transplantation	July 2013	Phase 4
NCT00368719	University of California, Davis	Atopic Dermatitis	September 2007	Phase 4
NCT01028716	Fred Hutchinson Cancer Center	Acute Biphenotypic Leukemia\|Acute Erythroid Leukemia in Remission\|Acute Leukemia in Remission\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Acute Myeloid Leukemia in Remission\|Acute Myeloid Leukemia With FLT3+ITD Mutation\|Acute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM\|Acute Myeloid Leukemia With Multilineage Dysplasia\|Acute Myeloid Leukemia With t(6;9) (p23;q34.1); DEK-NUP214\|Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Complete Remission\|B Acute Lymphoblastic Leukemia With t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)\|B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Burkitt Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Complete Remission\|DS Stage II Plasma Cell Myeloma\|DS Stage III Plasma Cell Myeloma\|Myelodysplastic Syndrome\|Recurrent Anaplastic Large Cell Lymphoma\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Recurrent Follicular Lymphoma\|Recurrent Hodgkin Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Plasma Cell Myeloma\|Refractory Plasma Cell Myeloma\|Secondary Acute Myeloid Leukemia\|T Lymphoblastic Lymphoma\|Hematopoietic Cell Transplant Recipient	February 8, 2010	Phase 2
NCT04069065	Chong Kun Dang Pharmaceutical	Liver Transplant	July 31, 2019	Phase 4
NCT02743247	Seoul National University Hospital\|Ministry of Food and Drug Safety, Korea	Healthy Volunteers	October 2015	Phase 1
NCT00406393	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Leukemia, Myelocytic, Acute\|Leukemia, Lymphocytic, Acute\|Leukemia, Myeloid, Chronic\|Myelodysplastic Syndromes	November 2006	Phase 3
NCT01773395	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center	Myelodysplastic Syndrome\|Acute Myeloid Leukemia\|Chronic Myelomonocytic Leukemia	January 8, 2013	Phase 2
NCT02382575	Nilratan Sircar Medical College	Nephrotic Syndrome	March 15, 2015	Phase 4
NCT01471444	M.D. Anderson Cancer Center\|Sanofi	Disorder Related to Bone Marrow Transplantation\|Leukemia\|Transplantation Infection	November 2, 2011	Phase 3
NCT01233570	University of Aberdeen	Crohn Disease		Phase 2
NCT00195429	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Failure\|Graft vs Host Disease	August 2005	Phase 4
NCT04496401	Nantes University Hospital\|Chiesi Farmaceutici S.p.A.	Kidney Transplantation\|Pancreas Transplantation\|Diabetes	September 28, 2020	Phase 4
NCT01790594	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation\|Rho Federal Systems Division, Inc.\|Bristol-Myers Squibb	Simultaneous Kidney and Pancreas Transplantation	February 2013	Phase 2
NCT00905515	East Carolina University\|Astellas Pharma US, Inc.	Kidney Transplantation	August 2003	Phase 4
NCT04009525	First Affiliated Hospital of Guangxi Medical University\|Peking University People´s Hospital\|Ruijin Hospital\|The 923th Hospital of People´s Liberation Army\|Fourth Affiliated Hospital of Guangxi Medical University\|Liuzhou General Hospital\|Hainan General Hospital\|The Affiliated Hospital Of Guizhou Medical University\|The First People´s Hospital of Yunnan	Thalassemia Major	June 1, 2019	Phase 4
NCT01884571	Emory University\|ALS Association	Amyotrophic Lateral Sclerosis (ALS)	October 2013	Phase 2
NCT00404794	Hospital Authority, Hong Kong\|The University of Hong Kong	Lupus Nephritis\|Glomerulonephritis, Membranous	November 2005	Phase 3
NCT00639717	University of Michigan Rogel Cancer Center\|Mallinckrodt\|Amgen	Graft Versus Host Disease	March 2009	Phase 2
NCT01653847	Northwestern University\|Novartis	End Stage Renal Failure With Renal Transplant	February 2013	Not Applicable
NCT03128359	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Leukemia\|Chronic Lymphocytic Leukemia+Small Lymphocytic Lymphoma\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Diffuse Large B-Cell Lymphoma\|Follicular Lymphoma\|Graft Versus Host Disease\|Hodgkin Lymphoma\|Mantle Cell Lymphoma\|Marginal Zone Lymphoma\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes\|Recurrent Plasma Cell Myeloma\|Refractory Plasma Cell Myeloma\|Secondary Myelodysplastic Syndrome	May 30, 2017	Phase 2
NCT01044745	University of Nebraska\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Mycosis Fungoides+Sezary Syndrome\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Small Lymphocytic Lymphoma\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Waldenström Macroglobulinemia	December 2009	Phase 2
NCT05221411	Leiden University Medical Center	Autoimmune Hepatitis	January 19, 2022	Phase 4
NCT03194321	Cedars-Sinai Medical Center\|Astellas Pharma Inc	End Stage Renal Disease	September 11, 2017	Phase 4
NCT00049504	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hematopoietic+Lymphoid Cancer\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Peripheral T-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage II Multiple Myeloma\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Childhood Hodgkin Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Childhood Hodgkin Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Small Lymphocytic Lymphoma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	January 2002	Phase 2
NCT02091973	Chulalongkorn University	microRNA Profiles	June 2010	Not Applicable
NCT00807690	Oslo University Hospital	Vitiligo	November 2005	Phase 3
NCT00048399	Baylor College of Medicine\|The Methodist Hospital Research Institute	Graft Failure	December 2000	Phase 1\|Phase 2
NCT00146614	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Massachusetts General Hospital	Graft Versus Host Disease\|Hematologic Malignancies	July 2002	Phase 2
NCT01316133	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Lupus Nephritis	April 19, 2011	Phase 4
NCT04701528	Leiden University Medical Center\|Aurinia Pharmaceuticals Inc.	Covid19\|Kidney Transplant Infection	November 15, 2020	Phase 2
NCT04420195	NYU Langone Health	Lung Transplant	October 23, 2020	Not Applicable
NCT00506922	M.D. Anderson Cancer Center\|Astex Pharmaceuticals, Inc.	Leukemia\|Lymphoma	September 2000	Phase 1\|Phase 2
NCT00275535	Mayo Clinic\|Wyeth is now a wholly owned subsidiary of Pfizer\|Genzyme, a Sanofi Company\|Roche Pharma AG	Kidney Diseases	April 2001	Phase 4
NCT00693446	Nantes University Hospital	Pancreas Transplantation\|Kidney Transplantation	April 2004	Phase 4
NCT00543569	Astellas Pharma Inc	Kidney Transplantation	February 2008	Phase 2
NCT01659606	Boston Children´s Hospital\|Dana-Farber Cancer Institute\|Children´s Hospital Medical Center, Cincinnati\|Children´s Hospital Los Angeles\|Fred Hutchinson Cancer Research Center+University of Washington Cancer Consortium\|Baylor College of Medicine\|Children´s Hospital of Philadelphia\|University of Wisconsin, Madison\|Karolinska University Hospital\|Hackensack Meridian Health\|Duke University\|Oslo University Hospital\|Children´s Mercy Hospital Kansas City\|Mayo Clinic\|University of Chicago\|Massachusetts General Hospital	Dyskeratosis Congenita\|Hoyeraal Hreidarsson Syndrome\|Revesz Syndrome\|Aplastic Anemia	July 2012	Phase 2
NCT03670966	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Acute Myeloid Leukemia in Remission\|Chronic Myelomonocytic Leukemia\|Myelodysplastic Syndrome With Excess Blasts\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Recurrent Mixed Phenotype Acute Leukemia\|Refractory Mixed Phenotype Acute Leukemia\|Hematopoietic and Lymphoid Cell Neoplasm	July 10, 2019	Phase 1\|Phase 2
NCT00654355	Wake Forest University\|Wake Forest University Health Sciences	Atopic Dermatitis	April 2008	Phase 4
NCT00027573	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Kidney Cancer	October 2001	Phase 2
NCT03751332	Medical University of Vienna	Immunosuppression\|Renal Failure	March 2008	Phase 4
NCT03644485	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Kidney Transplant	October 22, 2018	Phase 4
NCT02861417	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Hematopoietic and Lymphoid Cell Neoplasm\|High Risk Acute Myeloid Leukemia\|High Risk Myelodysplastic Syndrome\|Lymphoproliferative Disorder\|Myelodysplastic Syndrome\|Myelodysplastic+Myeloproliferative Neoplasm\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent High Risk Myelodysplastic Syndrome\|Recurrent Hodgkin Lymphoma\|Recurrent Myelodysplastic Syndrome\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma	August 5, 2016	Phase 2
NCT00782379	Northside Hospital, Inc.	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	October 2008	Phase 2
NCT02036554	Seoul St. Mary´s Hospital\|Novartis	Kidney; Complications, Allograft	March 2013	Phase 4
NCT00987103	Maastricht University Medical Center	Organ Transplantation	September 2009	Phase 1
NCT00757874	Deana Funaro\|Astellas Pharma Inc\|St. Justine´s Hospital	Vulvar Lichen Sclerosus	April 2006	Phase 2
NCT01203722	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Hematologic Malignancies	September 2010	Phase 1\|Phase 2
NCT02014103	University of Cincinnati\|University of Colorado, Denver\|Children´s Hospital Medical Center, Cincinnati	Complication of Transplant	March 2015	Phase 4
NCT04503616	NYU Langone Health	Graft-versus-host Disease	July 21, 2020	Phase 1\|Phase 2
NCT01333410	Mahidol University	Vitiligo	June 2009	Phase 4
NCT01764581	University of Bologna	Liver Disease	July 2008	Not Applicable
NCT01371344	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Heart Transplantation\|Kidney Transplantation\|Liver Transplantation	June 24, 2011	Phase 4
NCT04177004	City of Hope Medical Center\|National Cancer Institute (NCI)	Allogeneic Hematopoietic Stem Cell Transplant Recipient\|Hematopoietic and Lymphoid Cell Neoplasm	April 30, 2021	Phase 1
NCT05294666	Peking University Third Hospital	Graft Versus Host Disease in Eye	April 1, 2020	Phase 4
NCT00496483	Veloxis Pharmaceuticals\|CTI Clinical Trial and Consulting Services	Renal Failure	July 2007	Phase 2
NCT00002809	Temple University	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	August 1996	Phase 2
NCT00006042	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	December 1999	Phase 1
NCT00070135	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome	January 2004	Phase 2
NCT01649609	Columbia University\|Pfizer\|Cornell University	BK Viremia\|BK Nephropathy	March 2012	Not Applicable
NCT02839941	The First Affiliated Hospital with Nanjing Medical University	Kidney Transplantation	August 2016	Not Applicable
NCT02702960	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|Fibrolamellar Cancer Foundation	Fibrolamellar Hepatocellular Carcinoma\|Hepatocellular Carcinoma (Fibrolamellar Variant)\|Hepatocellular Carcinoma	March 2016	Phase 2
NCT01429844	Universitätsklinikum Hamburg-Eppendorf	Bronchiolitis Obliterans\|Immunosuppression	January 2001	Phase 3
NCT01053247	Fougera Pharmaceuticals Inc.	Atopic Dermatitis	January 2008	Phase 3
NCT00623012	Yale University	Graft Versus Host Disease	February 2008	Phase 1\|Phase 2
NCT03500848	Southern Medical University, China\|First Affiliated Hospital, Sun Yat-Sen University\|Nanfang Hospital of Southern Medical University	Liver Transplantation	May 1, 2018	Phase 2\|Phase 3
NCT00882895	Washington University School of Medicine	Lymphoma, Non-Hodgkin	May 5, 2009	Phase 2
NCT04262843	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|High Risk Myelodysplastic Syndrome\|Myelodysplastic Syndrome	February 7, 2020	Phase 2
NCT02137239	Bristol-Myers Squibb	Kidney Transplantation	December 31, 2015	Phase 2
NCT01744470	University Hospital, Tours\|Astellas Pharma Inc	De Novo Transplant Disease	May 2012	Phase 4
NCT01005316	National Institute of Allergy and Infectious Diseases (NIAID)\|National Heart, Lung, and Blood Institute (NHLBI)	Pediatric Heart Transplantation\|Pediatric Heart Transplant Recipients	January 2010
NCT00589563	City of Hope Medical Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Infection\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Precancerous Condition\|Secondary Myelofibrosis\|Small Intestine Cancer	May 2007	Phase 2
NCT01318915	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Renal Transplant Recipients	July 25, 2011	Early Phase 1
NCT03083782	Thomas Jefferson University\|Bristol-Myers Squibb	Venous Thromboembolism\|Pharmacokinetics\|Healthy	April 18, 2017	Phase 1
NCT00691145	Astellas Pharma Inc	Dermatitis, Atopic	October 2002	Phase 3
NCT00934791	Mayo Clinic\|Wyeth is now a wholly owned subsidiary of Pfizer	Polycystic Liver Disease	February 2009	Not Applicable
NCT01701986	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Hematopoietic Cell Transplantation Recipient\|Refractory B-Cell Non-Hodgkin Lymphoma\|Refractory Hodgkin Lymphoma\|Refractory T-Cell Non-Hodgkin Lymphoma	October 25, 2012	Phase 1\|Phase 2
NCT05088356	Stanford University\|Orca Biosystems, Inc.	Allogeneic Hematopoietic Cell Transplantation (HCT)\|Advanced Hematologic Malignancies\|Acute Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndromes\|Myeloproliferative Disorders	September 7, 2021	Phase 1
NCT01288521	Sony Tuteja\|American College of Clinical Pharmacy\|University of Iowa	Kidney Transplantation	October 2008	Phase 4
NCT01790568	University of Michigan Rogel Cancer Center	Graft vs Host Disease\|Hematologic Neoplasms\|Non-Neoplastic Hematologic and Lymphocytic Disorder	December 2014	Phase 2
NCT00931255	University of Maryland, Baltimore\|Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplant\|Delayed Graft Function	April 2009	Phase 4
NCT01328834	Sun Yat-sen University	Nephritis, Lupus	January 2011	Phase 3
NCT00189787	Astellas Pharma Inc\|Astellas Pharma Europe B.V.	Asthma, Bronchial\|Bronchial Asthma		Phase 2
NCT03828682	Simon Tremblay, PharmD, PhD\|Veloxis Pharmaceuticals\|University of Cincinnati	Kidney Transplantation\|Immunosuppression	June 21, 2019	Phase 4
NCT05621759	NYU Langone Health	Graft Vs Host Disease	August 23, 2022	Phase 2
NCT00789308	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|Clinical Islet Transplantation Consortium	Diabetes Mellitus, Type I	July 11, 2008	Phase 2
NCT01342016	Astellas Pharma Inc\|Astellas Pharma China, Inc.	Lupus Nephritis	April 2011	Phase 3
NCT01139450	Fougera Pharmaceuticals Inc.	Atopic Dermatitis	January 2008	Phase 3
NCT01068067	Sun Yat-sen University\|First Affiliated Hospital, Sun Yat-Sen University	Renal Transplantation	March 2010	Not Applicable
NCT04232085	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Primary Immune Deficiency Disorder\|Immune Deficiency Disease\|Bone Marrow Failure	February 12, 2020	Phase 2
NCT00612274	Yale University	Stem Cell Transplantation	October 2007	Early Phase 1
NCT03626714	Auritec Pharmaceuticals\|National Institute of Allergy and Infectious Diseases (NIAID)	Organ Transplant Rejection\|Psoriasis	October 16, 2018	Early Phase 1
NCT00914940	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	December 17, 2009	Phase 2
NCT02711826	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation	Kidney Transplant\|Adult Living Donor Kidney Transplant Recipients\|Renal Transplant\|Living Kidney Donor	September 20, 2016	Phase 1\|Phase 2
NCT00311311	Pfizer	Atherosclerosis\|Kidney Failure	April 2006	Phase 3
NCT01685411	Masonic Cancer Center, University of Minnesota	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Myelodysplastic Syndrome	January 2013	Not Applicable
NCT00282243	Astellas Pharma Inc	Liver Transplantation	February 2003	Phase 2
NCT00821587	University of Florida\|Novartis Pharmaceuticals	Hepatitis C	June 2004	Phase 4
NCT01754389	Dana-Farber Cancer Institute	Graft Versus Host Disease	January 2013	Phase 2
NCT02970630	Chiesi Farmaceutici S.p.A.\|Cromsource	Kidney Transplantation	January 2017	Phase 2
NCT03234673	Assiut University	Vitiligo Vulgaris	August 2017	Phase 1
NCT00717379	Astellas Pharma Inc	Kidney Transplantation\|Kidney Failure, Chronic\|Renal Insufficiency, Chronic	May 2007	Phase 4
NCT03680092	Dimitrios Tzachanis, MD PhD\|Bristol-Myers Squibb\|University of California, San Diego	GVHD\|Hematologic Neoplasms	November 26, 2019	Phase 2
NCT00006747	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Lymphoma	November 2000	Phase 2
NCT01904136	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Acute Myeloid Leukemia With Gene Mutations\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|de Novo Myelodysplastic Syndrome\|Myelodysplastic Syndrome\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Therapy-Related Acute Myeloid Leukemia	April 22, 2014	Phase 1\|Phase 2
NCT03105466	Zhongshan Ophthalmic Center, Sun Yat-sen University	Corneal Transplantation	February 2016	Not Applicable
NCT03347357	Shandong University	Nephrotic Syndrome	January 1, 2012	Phase 4
NCT03365141	The Catholic University of Korea	Vitiligo\|Treatment\|Intralesional Injection\|Corticosteroid	November 14, 2017	Not Applicable
NCT04207177	Oslo University Hospital	Kidney Transplant; Complications\|Immune Suppression	October 30, 2019	Phase 4
NCT01488253	The Korean Society of Blood and Marrow Transplantation\|Asan Medical Center\|Chonbuk National University Hospital\|Chonnam National University Hospital\|Chung-Ang University Hosptial, Chung-Ang University College of Medicine\|Daegu Catholic University Medical Center\|Ewha Womans University Mokdong Hospital\|Gachon University Gil Medical Center\|Inha University Hospital\|Inje University\|Keimyung University Dongsan Medical Center\|Korea University Anam Hospital\|Pusan National University Hospital\|Samsung Medical Center\|Severance Hospital\|Seoul St. Mary´s Hospital\|Seoul National University Hospital\|Soonchunhyang University Hospital	Acute Leukemia in Remission\|Myelodysplastic Syndromes\|Leukemia, Myeloid, Chronic-Phase\|Leukemia, Myeloid, Accelerated-Phase	January 2012	Phase 2
NCT01698541	University of Oslo School of Pharmacy\|Oslo University Hospital	End Stage Renal Disease	February 2013	Phase 4
NCT01010217	M.D. Anderson Cancer Center	Blood Stem Cell Transplant Failure\|Leukemia\|Hematologic Malignancies	November 5, 2009	Phase 2
NCT00933231	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Kidney Transplantation	August 17, 2009	Phase 3
NCT00171496	Novartis	Kidney Transplant	October 2003	Phase 4
NCT00136903	Mesoblast, Inc.\|Mesoblast, Ltd.	Graft Vs Host Disease	April 27, 2005	Phase 2
NCT05364762	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Chronic Myelomonocytic Leukemia\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Primary Myelofibrosis\|Secondary Myelofibrosis	November 20, 2022	Phase 2
NCT00295607	Astellas Pharma Inc	Hepatitis C\|Liver Transplantation	June 2005	Phase 2
NCT00150891	University of Giessen\|Heidelberg University\|Astellas Pharma Inc\|Novartis\|Fresenius AG\|Hoffmann-La Roche\|Biotest	Renal Failure, Chronic	January 1998
NCT03712878	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematopoietic and Lymphoid Cell Neoplasm	September 19, 2018	Phase 2
NCT01517984	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation	Kidney Transplant Recipients	November 2010	Phase 2
NCT00972101	M.D. Anderson Cancer Center	Stem Cell Transplantation\|Leukemia\|Lymphoma\|Pediatric Disorders	September 2009	Phase 1
NCT05148715	Université de Sherbrooke\|McMaster University	Organ Transplant Failure or Rejection\|Brain Death\|Ischemic Reperfusion Injury	January 2022	Phase 2
NCT03864926	University of Wisconsin, Madison\|Veloxis Pharmaceuticals	Delayed Graft Function	March 18, 2019	Phase 4
NCT00970073	The Cleveland Clinic\|Genzyme, a Sanofi Company	Liver Transplantation	August 2009	Not Applicable
NCT02251821	Fred Hutchinson Cancer Center\|Incyte Corporation\|National Cancer Institute (NCI)	Primary Myelofibrosis\|Secondary Myelofibrosis	October 20, 2014	Phase 2
NCT04657562	National Science Centre, Poland\|Medical University of Warsaw	Immunosuppression\|Kidney Transplant Rejection\|Kidney Transplant; Complications\|Liver Transplant Rejection\|Liver Transplant; Complications\|Metabolism Medication Toxicity\|Genetic Predisposition	August 1, 2020
NCT01163357	City of Hope Medical Center\|National Cancer Institute (NCI)	Autologous Hematopoietic Stem Cell Transplant Recipient\|Loss of Chromosome 17p\|Plasma Cell Leukemia\|Recurrent Plasma Cell Myeloma\|Refractory Plasma Cell Myeloma	January 28, 2011	Phase 1
NCT00182559	Medical University of Vienna	End Stage Renal Disease	April 2004	Phase 4
NCT00579111	Baylor College of Medicine\|Center for Cell and Gene Therapy, Baylor College of Medicine\|The Methodist Hospital Research Institute	Myelodysplastic and Myeloproliferative Disorders\|Acute Myelogenous Leukemia\|Acute Lymphoblastic Leukemia\|Chronic Myelogenous Leukemia\|Multiple Myeloma\|Plasma Cell Dyscrasia\|Lymphoproliferative Disorders\|Hematologic Diseases	June 2007	Phase 1\|Phase 2
NCT04114097	Jacob Thyssen\|LEO Pharma\|University Hospital, Gentofte, Copenhagen	Atopic Dermatitis\|Atopic Eczema	August 22, 2019	Phase 4
NCT02208037	National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Acute Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplasia\|Chronic Lymphocytic Leukemia\|Small Lymphocytic Lymphoma\|Lymphoma, B-Cell\|Lymphoma, Follicular\|Lymphoma, Large B-Cell, Diffuse\|Hodgkin´s Lymphoma	August 2014	Phase 2
NCT00223054	University Hospital Schleswig-Holstein\|University of Kiel	Function of Renal Transplant	March 2005
NCT00707759	Fondo Nacional de Desarrollo Científico y Tecnológico, Chile	Kidney Diseases	June 2008	Phase 3
NCT00589316	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|CD45-Positive Neoplastic Cells Present\|Chronic Myelomonocytic Leukemia\|Previously Treated Myelodysplastic Syndrome\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ring Sideroblasts\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts	October 5, 2007	Phase 1
NCT00369382	Wyeth is now a wholly owned subsidiary of Pfizer	Graft Rejection\|Kidney Failure	September 2006	Phase 4
NCT00560378	Astellas Pharma Inc	Dermatitis, Atopic\|Eczema, Atopic	June 1998	Phase 3
NCT00766909	University of Aarhus	Complications of Transplanted Organs and Tissue\|Diabetes Mellitus Nos New Onset	March 2008	Phase 4
NCT00787761	Northside Hospital, Inc.\|Blood and Marrow Transplant Group of Georgia	Myeloproliferative Disorders\|Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	April 2007	Phase 2
NCT02545972	Newark Beth Israel Medical Center	Heart Failure	February 2016	Phase 4
NCT00229138	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation	September 2005	Phase 4
NCT03047733	Ajou University School of Medicine	Dermatologic Disease\|Vitiligo	July 21, 2015	Not Applicable
NCT02555787	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Kidney Transplantation	March 5, 2015
NCT00443105	Assaf-Harofeh Medical Center	Allergic Conjunctivitis		Phase 2
NCT00667160	Astellas Pharma Inc	Dermatitis, Atopic	December 2002	Phase 4
NCT01279616	Nationwide Children´s Hospital	Sickle Cell Disease	September 2010	Phase 2
NCT00779792	Odense University Hospital\|LEO Pharma\|University of Southern Denmark	Dermatitis, Contact\|Dermatitis, Occupational	September 2008	Phase 4
NCT04339777	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Lymphoproliferative Disorders\|Autoimmune Lymphoproliferative\|Immune System Diseases\|Common Variable Immunodeficiency\|Primary T-cell Immunodeficiency Disorders	September 22, 2020	Phase 2
NCT00857389	M.D. Anderson Cancer Center	Stem Cell Transplantation\|Leukemia\|Lymphoma	March 2, 2009	Phase 2
NCT03088709	Loyola University	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome\|Non-hodgkin Lymphoma\|Chronic Lymphocytic Leukemia	January 18, 2017	Phase 2
NCT03654794	Rennes University Hospital	Hemochromatosis	October 24, 2013
NCT03386305	Albert Einstein Healthcare Network\|Veloxis Pharmaceuticals	Post Liver Transplant	December 13, 2017	Phase 2\|Phase 3
NCT01875237	M.D. Anderson Cancer Center\|Bellicum Pharmaceuticals	Leukemia\|Myeloma\|Myeloproliferative Diseases	December 27, 2013	Phase 1\|Phase 2
NCT01586845	Aurinia Pharmaceuticals Inc.	Renal Transplantation	March 2013	Phase 3
NCT02077556	National Taiwan University Hospital	Drug Interaction Potentiation	April 2014	Phase 4
NCT01095172	Guy´s and St Thomas´ NHS Foundation Trust\|Astellas Pharma Europe Ltd.	Function of Renal Transplant	November 2010	Phase 4
NCT02441803	M.D. Anderson Cancer Center	Leukemia	September 14, 2015	Phase 2
NCT01935128	University of Toledo Health Science Campus\|Novartis Pharmaceuticals\|University of Toledo	Renal Transplant	July 3, 2013	Phase 4
NCT03076151	University Hospital, Limoges	Transplantation\|Kidney\|Pharmacokinetic	February 12, 2018	Phase 4
NCT02294552	Ivan S Moiseev\|St. Petersburg State Pavlov Medical University	Acute Myeloid Leukemia\|Acute Lymphoid Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Chronic Lymphocytic Leukemia\|Immune System Diseases	October 2014	Phase 2
NCT03256864	Chang Gung Memorial Hospital	Liver Transplantation	January 2016	Phase 4
NCT01244659	EMS	Renal Transplant	May 2014	Phase 3
NCT00113269	Astellas Pharma Inc	Kidney Transplantation	May 2005	Phase 4
NCT02566304	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Acute Myeloid Leukemia\|Acute Myeloid Leukemia in Remission\|Aplastic Anemia\|Chronic Myelomonocytic Leukemia\|Hodgkin Lymphoma\|Indolent Non-Hodgkin Lymphoma\|Malignant Neoplasm\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Plasma Cell Myeloma\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ring Sideroblasts\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts	November 13, 2015	Phase 2
NCT00862979	Novartis Pharmaceuticals\|Novartis	Heart Transplantation	February 24, 2009	Phase 4
NCT04773392	University of Southern California\|Veloxis Pharmaceuticals	Kidney Transplantation\|Kidney Transplant Rejection	November 23, 2021	Phase 4
NCT00039377	National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Remission	April 2002	Phase 2
NCT04825262	Singapore General Hospital	Kidney Transplant Rejection\|Kidney Transplant; Complications	February 1, 2021	Not Applicable
NCT00564538	University of Nebraska\|Genzyme, a Sanofi Company	Liver Transplantation\|Liver Disease\|Immunosuppression	December 2007	Phase 4
NCT01265537	University of British Columbia\|Astellas Pharma Canada, Inc.	Acute Graft Rejection\|Diabetes	June 24, 2011	Not Applicable
NCT03959241	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)\|National Marrow Donor Program	Acute Leukemia\|Chronic Myelogenous Leukemia (CML)\|Myelodysplasia\|Lymphoma	June 25, 2019	Phase 3
NCT00304018	University of California, San Francisco\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	October 2002	Phase 1
NCT03645057	University of Rochester	Atopic Dermatitis	February 20, 2019	Phase 3
NCT00843856	Imperial College Healthcare NHS Trust	Glomerulonephritis, Membranous	March 3, 2009	Phase 4
NCT01797341	University Health Network, Toronto	Kidney-Pancreas Transplantation	June 2013	Phase 3
NCT00023244	National Institute of Allergy and Infectious Diseases (NIAID)\|Cooperative Clinical Trials in Pediatric Transplantation	End-Stage Renal Disease	January 2001	Phase 2
NCT02248597	Wake Forest University Health Sciences\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Hematopoietic+Lymphoid Cancer	February 25, 2015	Phase 2
NCT02444143	University of Illinois at Chicago\|Astellas Pharma US, Inc.	Kidney Transplantation	May 2015	Phase 4
NCT01181271	Massachusetts General Hospital\|Dana-Farber Cancer Institute	Diffuse, Large B-Cell, Lymphoma\|Lymphoma, Low-Grade\|T-Cell Lymphoma\|Mantle-Cell Lymphoma\|Hodgkin´s Lymphoma\|Chronic Lymphocytic Leukemia\|Lymphoma, Small Lymphocytic	August 2010	Phase 2
NCT00369226	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Millennium Pharmaceuticals, Inc.	Hematologic Malignancies	August 2006	Phase 1\|Phase 2
NCT04903054	National Institute of Allergy and Infectious Diseases (NIAID)\|Bristol-Myers Squibb\|PPD	Kidney Transplantation\|Renal Transplant Recipients	October 2021	Phase 2
NCT01490723	M.D. Anderson Cancer Center\|Spectrum Pharmaceuticals, Inc	Leukemia\|Lymphoma	January 2013	Phase 2
NCT00337493	Hoffmann-La Roche	Kidney Transplantation	December 2005	Phase 4
NCT00369161	Novartis	Renal Transplantation	June 2006	Phase 4
NCT01535547	Astellas Pharma Inc\|Basilea Pharmaceutica International Ltd	Pharmacokinetics of Isavuconazole\|Pharmacokinetics of Tacrolimus\|Healthy Volunteers	December 2011	Phase 1
NCT00298662	Clinique de sclérose en plaques et neuromusculaire de l´Outaouais	Multiple Sclerosis	February 2003	Phase 2
NCT01166724	The Cleveland Clinic\|Pfizer	Kidney Transplant	July 2010	Phase 3
NCT00609388	Medical University of Vienna	Ischemia Reperfusion Injury	January 2008	Phase 4
NCT04542733	King Chulalongkorn Memorial Hospital	Kidney Transplant Infection\|BK Virus Infection	February 10, 2021	Not Applicable
NCT02877082	Emory University	Acute Leukemia\|Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Diffuse Large B-Cell Lymphoma\|Follicular Lymphoma\|Graft Versus Host Disease\|Mantle Cell Lymphoma\|Marginal Zone Lymphoma\|Myelodysplastic Syndrome\|Myelofibrosis\|Myeloproliferative Neoplasm\|Small Lymphocytic Lymphoma	September 2016	Phase 2
NCT02377609	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Validation\|Dried Blood Spot\|Transplant Patients	October 2013
NCT02653196	Montefiore Medical Center\|Children´s Hospital Los Angeles\|Nationwide Children´s Hospital	Neuroepithelial Tumor\|Solid Tumor\|Allogeneic Hematopoietic Stem Cell Transplantation	September 2015	Early Phase 1
NCT02356146	Chulalongkorn University	Kidney Transplantation Recipients	January 2012
NCT02466997	University Hospital, Bordeaux	Vitiligo	February 23, 2016	Phase 3
NCT01469884	Irmandade Santa Casa de Misericórdia de Porto Alegre\|Novartis	Renal Allograft\|Hepatitis C	November 2011	Phase 4
NCT02115113	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	March 28, 2014	Phase 3
NCT02954198	Medical University of South Carolina	Immunosuppression	December 1, 2016	Not Applicable
NCT05577637	Combined Military Hospital Abbottabad	Vitiligo	May 1, 2021	Phase 1
NCT01875224	University of Arizona\|Bristol-Myers Squibb	New Onset Diabetes After Transplant\|Kidney Transplantation	August 2013	Phase 4
NCT01064791	Novartis Pharmaceuticals\|Novartis	Renal Transplantation	December 2009	Phase 2
NCT00553202	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	January 2008	Phase 2
NCT01256294	Novartis\|Sandoz	Renal Transplant	October 2010	Phase 4
NCT00004878	Jonsson Comprehensive Cancer Center	Graft Versus Host Disease\|Leukemia		Phase 2
NCT01962922	Veloxis Pharmaceuticals	Renal Failure	November 2013	Phase 3
NCT00282568	Astellas Pharma Inc	Kidney Transplantation	August 2002	Phase 2
NCT05353010	HK inno.N Corporation	Healthy	May 1, 2022	Phase 1
NCT01027000	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Genentech, Inc.\|Biologics, Inc.	Leukemia\|Lymphoma	February 2010	Phase 2
NCT00801957	Astellas Pharma Inc	Atopic Dermatitis	March 2003	Phase 2
NCT03152019	Hospices Civils de Lyon	Hemorrhagic Hereditary Telangiectasia (HHT)	May 22, 2017	Phase 2
NCT02337036	Assistance Publique - Hôpitaux de Paris\|Cliniques universitaires Saint-Luc- Université Catholique de Louvain	Liver Transplantation, Child	December 2013	Not Applicable
NCT00282282	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital	Graft Versus Host Disease\|GVHD	January 2006	Phase 2
NCT00481481	Astellas Pharma Inc	Transplantation	April 2007	Phase 3
NCT03240822	Wake Forest University Health Sciences	Urologic Injuries\|Genital Diseases, Male\|Amputation	January 2017	Phase 1
NCT01804634	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Refractory and+or Relapsed Metastatic Solid Tumors	March 27, 2013	Phase 2
NCT02790515	St. Jude Children´s Research Hospital	Acute Lymphoblastic Leukemia (ALL)\|Acute Myeloid Leukemia (AML)\|Myeloid Sarcoma\|Chronic Myeloid Leukemia (CML)\|Juvenile Myelomonocytic Leukemia (JMML)\|Myelodysplastic Syndrome (MDS)\|Non-Hodgkin Lymphoma (NHL)	July 14, 2016	Phase 2
NCT00720629	H. Lee Moffitt Cancer Center and Research Institute\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Graft Versus Host Disease	December 2007	Phase 2
NCT00322101	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Acute Myeloid Leukemia+Transient Myeloproliferative Disorder\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|de Novo Myelodysplastic Syndromes\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes	January 2006	Phase 3
NCT00765661	Veloxis Pharmaceuticals\|CTI Clinical Trial and Consulting Services\|Aptuit Inc.	Kidney Failure\|Renal Failure	September 2008	Phase 2
NCT03438773	California Institute of Renal Research\|Balboa Institute of Transplantation\|University of California, San Diego	Kidney Transplant; Complications\|Kidney Transplant Failure and Rejection	July 11, 2018	Phase 1
NCT00041288	University of Texas Southwestern Medical Center	Leukemia\|Lymphoma	October 2001	Phase 2
NCT04530487	M.D. Anderson Cancer Center	Desmoplastic Small Round Cell Tumor\|Ewing Sarcoma+Peripheral Primitive Neuroectodermal Tumor\|Recurrent Desmoplastic Small Round Cell Tumor\|Recurrent Malignant Peripheral Nerve Sheath Tumor\|Recurrent Malignant Solid Neoplasm\|Recurrent Neuroblastoma\|Recurrent Rhabdomyosarcoma\|Refractory Desmoplastic Small Round Cell Tumor\|Refractory Malignant Peripheral Nerve Sheath Tumor\|Refractory Malignant Solid Neoplasm\|Refractory Neuroblastoma\|Refractory Rhabdomyosarcoma	August 19, 2020	Phase 2
NCT03673527	LEO Pharma	Healthy	November 22, 2018	Phase 1
NCT00928018	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|National Cancer Institute (NCI)	Non-hodgkin Lymphoma\|Hodgkin Lymphoma	June 2009	Phase 3
NCT00560326	Astellas Pharma Inc	Dermatitis, Atopic	June 2003	Phase 2
NCT00166712	Northwestern University\|Roche Pharma AG	Kidney Transplant Failure and Rejection	April 2005	Phase 4
NCT02057484	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Liver Transplant\|Kidney Transplant	March 3, 2014
NCT02909335	Rennes University Hospital	Liver Transplantation	November 2016	Phase 3
NCT00148746	Technische Universität Dresden	Moderate to Severe Atopic Dermatitis	May 2004	Not Applicable
NCT01780844	Astellas Pharma Global Development, Inc.\|Kyowa Kirin Co., Ltd.\|Astellas Pharma Inc	Kidney Transplantation	March 5, 2013	Phase 2
NCT00731874	Weill Medical College of Cornell University	Immunosuppression	August 2008	Phase 4
NCT05109390	Alexion Pharmaceuticals\|Achillion, a wholly owned subsidiary of Alexion	Healthy	July 27, 2018	Phase 1
NCT03266393	Meghan Pearl, MD\|Veloxis Pharmaceuticals\|University of California, Los Angeles	Kidney Transplantation\|Renal Transplantation\|Grafting, Kidney	January 15, 2019	Phase 4
NCT00163657	Baylor Research Institute\|Baylor Health Care System\|Emory University\|University of Southern California\|Mayo Clinic - Scottsdale+Phoenix, Arizona\|New York Presbyterian Hospital\|Oregon Health and Science University\|New York University\|University of Cincinnati\|University of Alabama at Birmingham\|The University of Texas Health Science Center at San Antonio\|University of Chicago\|University of California, San Francisco\|Mayo Clinic - Rochester, Minnesota\|Medical University of South Carolina\|University of Virginia\|Lahey Clinic\|University of Medicine and Dentistry of New Jersey\|Northwestern Memorial Hospital	End Stage Liver Disease\|Hepatitis C	July 2002	Phase 4
NCT00034528	National Institute of Allergy and Infectious Diseases (NIAID)	Hemoglobinopathies\|Anemia, Sickle Cell\|Hemoglobin SC Disease\|Thalassemia\|Thalassemia Major	September 2001	Phase 2
NCT02799888	Affiliated Hospital to Academy of Military Medical Sciences	Graft-versus-host Disease\|Hematopoietic Stem Cell Transplantation	April 2014	Phase 2
NCT03979365	Mayo Clinic\|Veloxis Pharmaceuticals	Kidney Transplant Recipients	July 18, 2019	Phase 4
NCT00382109	Children´s Oncology Group\|National Cancer Institute (NCI)	B-cell Childhood Acute Lymphoblastic Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Graft Versus Host Disease\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	March 2007	Phase 3
NCT03865888	Pavly Moawd\|Cairo University	Dry Eye\|Sjogren Syndrome	October 30, 2018	Phase 3
NCT04477629	Marlena V. Habal\|Bristol-Myers Squibb\|Columbia University	Heart Transplantation	August 6, 2020	Phase 2
NCT02129582	Case Comprehensive Cancer Center	Acute Myeloid Leukemia\|Hematologic Malignancies\|Acute Lymphocytic Leukemia\|Non Hodgkin Lymphoma\|Hodgkin Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndrome\|Chronic Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Myelofibrosis\|Myeloproliferative Syndrome	November 5, 2014	Phase 1
NCT00262886	University of Rochester	Kidney Cancer	August 2001	Phase 2
NCT04380311	University of Utah\|National Heart, Lung, and Blood Institute (NHLBI)	Heart Transplant Failure and Rejection	May 1, 2020	Not Applicable
NCT04095858	OncoImmune, Inc.	Hematopoietic Stem Cell Transplantation\|Acute Graft Versus Host Disease\|Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia\|Myelodysplastic Syndromes	January 5, 2021	Phase 3
NCT00792948	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Adult L1 Acute Lymphoblastic Leukemia\|Adult L2 Acute Lymphoblastic Leukemia\|Adult T Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia	September 1, 2009	Phase 2
NCT01888432	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	September 25, 2013	Phase 3
NCT00014911	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Diabetes Mellitus, Insulin-Dependent	April 2001	Phase 2
NCT00040417	Baylor College of Medicine\|The Methodist Hospital Research Institute	Sickle Cell Anemia\|Hemoglobinopathy\|Thalassemia	August 2000	Phase 2
NCT04390685	Odense University Hospital	Lymphedema	February 26, 2020	Phase 1\|Phase 2
NCT01887171	Republican Scientific and Practical Center for Organ and Tissue Transplantation	Early Allograft Dysfunction\|Ischemic Reperfusion Injury\|Liver Transplantation\|Hyperfibrinolysis	July 2013	Not Applicable
NCT01169701	Novartis Pharmaceuticals\|Novartis	Renal Transplant	August 2010	Phase 4
NCT02556931	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Myelodysplastic Syndrome\|Chronic Myelomonocytic Leukemia\|Small Lymphocytic Lymphoma\|Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Chronic Myeloid Leukemia\|Chronic Myeloproliferative Disorders\|Multiple Myeloma\|Plasma Cell Neoplasm\|Plasma Cell Dyscrasia\|Myelofibrosis\|Polycythemia Vera\|Essential Thrombocythemia\|Plasma Cell Leukemia	December 2015	Phase 2
NCT00690105	Astellas Pharma Inc	Dermatitis, Atopic	February 2004	Phase 4
NCT00263328	Pfizer	Kidney Transplantation	December 2005	Phase 2
NCT01038167	Vertex Pharmaceuticals Incorporated\|Tibotec Pharmaceutical Limited	Hepatitis C	January 2010	Phase 1
NCT04559048	The Second Hospital of Tangshan\|Chinese PLA General Hospital	Chronic Pain\|Liver Transplantation	September 15, 2019
NCT03968588	Ajou University School of Medicine	Disorder Related to Renal Transplantation	July 29, 2014	Phase 4
NCT03699631	Medical College of Wisconsin	Hematologic Malignancy	November 6, 2018	Phase 2
NCT04370301	Fred Hutchinson Cancer Center	Primary Myelofibrosis\|Secondary Myelofibrosis	February 9, 2021	Phase 2
NCT04942730	St. Petersburg State Pavlov Medical University	Leukemia, Acute Lymphoblastic\|Myeloid Leukemia, Acute\|Biphenotypic Acute Leukemia\|Lymphoblastic Lymphoma\|Myelodysplastic Syndromes\|Myeloproliferative Neoplasm	January 21, 2021	Phase 2
NCT02608606	Pontificia Universidad Catolica de Chile	Evidence of Liver Transplantation\|Effects of Immunosuppressant Therapy	March 2015	Not Applicable
NCT00866684	Charite University, Berlin, Germany	Kidney Transplantation\|Skin Cancer	January 2007	Phase 4
NCT01002339	Armando Torres Ramírez\|Fundación Canaria Rafael Clavijo para la Investigación Biomédica	Diabetes Mellitus, Adult-Onset	February 2010	Phase 4
NCT04469842	Vanderbilt University Medical Center\|Veloxis Pharmaceuticals	Lung Transplant; Complications	October 1, 2022	Early Phase 1
NCT00567762	Astellas Pharma Inc	Keratoconjunctivitis\|Conjunctivitis	February 2004	Phase 3
NCT00555789	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation	October 2007	Phase 2
NCT00827099	Northside Hospital, Inc.	Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	June 2006	Phase 2
NCT01309477	Sun Yat-sen University	Nephrotic Syndrome	January 2011	Phase 3
NCT00129961	Wyeth is now a wholly owned subsidiary of Pfizer	Skin Neoplasms\|Kidney Transplantation	August 2005	Phase 4
NCT01479881	Tibotec Pharmaceuticals, Ireland	Hepatitis C Virus	October 2011	Phase 1
NCT00056979	Baylor College of Medicine\|The Methodist Hospital Research Institute	Inherited Metabolic Storage Diseases	June 2002	Phase 1\|Phase 2
NCT01246206	Barbara Ann Karmanos Cancer Institute	Hematological Malignancies	November 2010	Phase 2
NCT02453867	Klemens Budde\|Charite University, Berlin, Germany\|European Renal Association - European Dialysis and Transplant Association\|European Kidney Transplant Association (EKITA)\|DESCARTES Working Group On Transplantation	Immunosuppression After Renal Transplantation	December 2017	Phase 4
NCT00183248	University of Miami\|Immune Tolerance Network (ITN)	Kidney Transplantation\|Kidney Disease\|Kidney Failure	September 2004	Phase 1\|Phase 2
NCT01168219	National Cancer Institute (NCI)	Acute Myeloid Leukemia\|Adult Acute Megakaryoblastic Leukemia\|Adult Acute Monoblastic Leukemia\|Adult Acute Monocytic Leukemia\|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11\|Adult Acute Myeloid Leukemia With Maturation\|Adult Acute Myeloid Leukemia With Minimal Differentiation\|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11\|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1\|Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL\|Adult Acute Myeloid Leukemia Without Maturation\|Adult Acute Myelomonocytic Leukemia\|Adult Erythroleukemia\|Adult Pure Erythroid Leukemia\|Alkylating Agent-Related Acute Myeloid Leukemia\|de Novo Myelodysplastic Syndrome\|Myelodysplastic Syndrome\|Myelodysplastic Syndrome With Excess Blasts\|Recurrent Adult Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndrome	July 15, 2010	Phase 2
NCT00429143	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematologic Malignancies	January 2006	Phase 1\|Phase 2
NCT00301912	University of California, San Francisco\|National Cancer Institute (NCI)	Anemia\|Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	January 2002	Phase 2
NCT02345850	National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Acute Leukemia\|Myelodysplasia	August 2015	Phase 3
NCT03005236	University Hospital Birmingham NHS Foundation Trust	Kidney Transplant Failure and Rejection	April 2017	Phase 4
NCT03263052	University of Illinois at Chicago\|Veloxis Pharmaceuticals	Disorder Related to Renal Transplantation	July 1, 2017
NCT00096096	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	August 2004	Phase 2
NCT01824693	Children´s Oncology Group\|National Cancer Institute (NCI)	Juvenile Myelomonocytic Leukemia	June 24, 2013	Phase 2
NCT02891603	H. Lee Moffitt Cancer Center and Research Institute\|CTI BioPharma\|National Heart, Lung, and Blood Institute (NHLBI)	Graft Vs Host Disease\|GVHD	June 8, 2017	Phase 1\|Phase 2
NCT01591070	Pusan National University Hospital	Seborrheic Dermatitis	November 2010	Phase 4
NCT02548468	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Cutaneous T-Cell Non-Hodgkin Lymphoma\|Recurrent Mycosis Fungoides and Sezary Syndrome\|Stage IIB Mycosis Fungoides and Sezary Syndrome\|Stage IIIA Mycosis Fungoides and Sezary Syndrome\|Stage IIIB Mycosis Fungoides and Sezary Syndrome\|Stage IVA Mycosis Fungoides and Sezary Syndrome\|Stage IVB Mycosis Fungoides and Sezary Syndrome	November 20, 2015	Phase 1
NCT04198506	Philipps University Marburg Medical Center	Transplantation Lung	August 5, 2020	Not Applicable
NCT00874315	Nationwide Children´s Hospital	Neuroblastoma	September 2008	Phase 2
NCT01025817	Novartis Pharmaceuticals\|Novartis	Kidney Transplant	January 2010	Phase 3
NCT04220008	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent Aggressive Non-Hodgkin Lymphoma\|Recurrent B-Cell Non-Hodgkin Lymphoma\|Recurrent Burkitt Lymphoma\|Recurrent Diffuse Large B-Cell Lymphoma\|Recurrent High Grade B-Cell Lymphoma\|Recurrent T-Cell Non-Hodgkin Lymphoma\|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma	June 1, 2023	Phase 2
NCT02540395	Prof. Dr. Petra Reinke\|Charite University, Berlin, Germany	Disorder Related to Renal Transplantation\|Effects of Immunosuppressant Therapy	March 2015	Not Applicable
NCT01509300	Asan Medical Center	Acute Leukemia\|Myelodysplastic Syndrome\|Solid Tumors	January 2012	Phase 1\|Phase 2
NCT02145403	University of Michigan Rogel Cancer Center	Hematologic Malignancies\|Relapse\|Graft-Versus-Host Disease	October 2014	Phase 1\|Phase 2
NCT00293930	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Psoriasis		Phase 3
NCT00790439	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Diabetes Mellitus, Type I	July 2008	Phase 2
NCT00089037	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	June 2003	Phase 1\|Phase 2
NCT01451489	Nanjing University School of Medicine	FSGS	October 13, 2011	Not Applicable
NCT02075242	Asan Medical Center	HEPATITIS	January 2014	Phase 4
NCT00615667	Sun Yat-sen University	Kidney Diseases\|Nephrotic Syndrome\|Tacrolimus	June 2006	Phase 3
NCT04041219	Mayo Clinic	Immunosuppression\|Stem Cell Transplant\|Bone Marrow Transplant	June 17, 2019	Phase 4
NCT00189839	Astellas Pharma Inc	Kidney Transplantation	August 2004	Phase 3
NCT00240994	National Institute of Allergy and Infectious Diseases (NIAID)\|Cooperative Clinical Trials in Pediatric Transplantation	Kidney Failure, Chronic\|Kidney Transplantation\|Immunosuppression	January 2005	Phase 2
NCT02680717	Medical College of Wisconsin\|Mayo Clinic\|Seattle Children´s Hospital\|University of Toronto	Scleroderma	March 2016	Phase 1
NCT00296244	Thomas Jefferson University\|Novartis Pharmaceuticals	Liver Cirrhosis\|Liver Transplant Disorder	February 2006	Phase 4
NCT05490511	Indiana University	CBD\|Transplant Complication\|Kidney Disease, Chronic	September 2022	Phase 1
NCT02213068	Lorenzo Gallon\|Bristol-Myers Squibb\|Northwestern University	Transplant; Failure, Kidney\|EBV	July 2014	Phase 4
NCT03386539	Boston Children´s Hospital\|Stanford University\|United States Department of Defense	Pediatric Heart Transplantation\|Immunosuppression\|Chronic Kidney Diseases\|Cardiac Allograft Vasculopathy\|Heart Transplant Failure and Rejection\|Post-transplant Lymphoproliferative Disorder\|Heart Transplant Infection	January 29, 2018	Phase 3
NCT04403321	Peking Union Medical College Hospital	Aplastic Anemia\|Drug Effect	July 1, 2020	Phase 2
NCT01154387	Tolera Therapeutics, Inc	End Stage Renal Disease\|Renal Transplant	July 2010	Phase 1\|Phase 2
NCT00076570	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|National Institutes of Health Clinical Center (CC)	Kidney Transplantation	January 2004	Phase 2
NCT01471067	M.D. Anderson Cancer Center\|American Stem Cell, Inc.\|National Cancer Institute (NCI)	Blood And Marrow Transplantation\|Leukemia\|Lymphoma\|Transplantation Infection\|Transplantation, Bone Marrow	July 13, 2012	Phase 1
NCT02661035	Masonic Cancer Center, University of Minnesota	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myelogenous Leukemia\|Plasma Cell Leukemia\|Myelodysplastic Syndromes\|Chronic Lymphocytic Leukemia\|Small Lymphocytic Lymphoma\|B-Cell Lymphoma\|Follicular Lymphoma\|Lymphoplasmacytic Lymphoma\|Mantle-Cell Lymphoma\|Prolymphocytic Leukemia\|Lymphoblastic Lymphoma\|Burkitt´s Lymphoma\|Non-Hodgkin´s Lymphoma\|Multiple Myeloma\|Myeloproliferative Syndromes\|Hematological Diseases	March 9, 2017	Phase 2
NCT00321074	Astellas Pharma Inc	LIVER TRANSPLANTATION	May 2005	Phase 3
NCT00187915	University of Florida\|Hoffmann-La Roche	Transplant, Kidney	July 2003	Not Applicable
NCT00579527	Enzyvant Therapeutics GmBH\|National Institutes of Health (NIH)\|National Institute of Allergy and Infectious Diseases (NIAID)\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	DiGeorge Anomaly\|Complete DiGeorge Anomaly\|Complete Atypical DiGeorge Anomaly\|Complete DiGeorge Syndrome\|Complete Atypical DiGeorge Syndrome	December 19, 2005	Phase 1\|Phase 2
NCT01118013	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Lymphoproliferative Disorder\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	December 2010	Phase 2
NCT03602898	Fred Hutchinson Cancer Center	Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Myelodysplastic Syndrome\|Myelofibrosis\|Myeloproliferative Neoplasm\|Recurrent Acute Myeloid Leukemia\|Recurrent Hodgkin Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Refractory Acute Myeloid Leukemia\|Therapy-Related Acute Myeloid Leukemia	June 1, 2021	Phase 2
NCT01621477	St. Jude Children´s Research Hospital\|Assisi Foundation	Acute Lymphoblastic Leukemia\|Acute Myelocytic Leukemia\|Chronic Myelocytic Leukemia\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic Syndrome\|Hodgkin or Non-Hodgkin Lymphoma\|Sarcoma, Myeloid	August 2012	Phase 2
NCT01187953	Veloxis Pharmaceuticals	Renal Failure	September 2010	Phase 3
NCT00596947	University of Pennsylvania	Transplants and Implants	October 2005	Phase 4
NCT01572662	M.D. Anderson Cancer Center	Leukemia\|Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Chronic Lymphocytic Leukemia\|Myeloproliferative Diseases\|Non-Hodgkins Lymphoma\|Hodgkins Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndrome	April 11, 2012	Phase 2
NCT03823768	Medical University of South Carolina\|Veloxis Pharmaceuticals	Neurotoxicity\|Liver Transplant; Complications	January 31, 2020	Phase 4
NCT01820572	Bristol-Myers Squibb	Kidney Transplantation	March 27, 2013	Phase 3
NCT01346397	Russian Academy of Medical Sciences\|Russian Scientific Center of Surgery	Acute Graft Rejection\|Chronic Allograft Nephropathy\|Polyomavirus-related Transplant Nephropathy	April 2009
NCT00166556	Mayo Clinic\|University of Chicago\|Immune Tolerance Network (ITN)	Transplantation, Liver	January 2005	Phase 2
NCT05303727	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Neuroblastoma	August 2022	Phase 2
NCT02395497	Johns Hopkins University	Amputation\|Wounds and Injuries\|Amputation, Traumatic\|Urologic Surgical Procedures, Male\|Amputation, Traumatic+Surgery\|Penis+Transplantation\|Penis+Surgery\|Penis+Injuries	June 2014	Phase 2\|Phase 3
NCT02130817	University of Wisconsin, Madison\|Bristol-Myers Squibb	End Stage Renal Disease\|Antibody Mediated Rejection	September 24, 2014	Phase 4
NCT03461445	University of California, Davis\|Veloxis Pharmaceuticals	Kidney Transplant; Complications\|Toxicity\|Drug Toxicity\|Neurotoxicity	April 1, 2018	Phase 4
NCT00053196	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma\|Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myeloproliferative Neoplasms	December 2002	Phase 2
NCT00434850	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Diabetes Mellitus, Type 1	October 2006	Phase 2
NCT00480610	Astellas Pharma Inc	Dermatitis, Atopic	April 2004	Phase 3
NCT02627573	St. Petersburg State Pavlov Medical University	Leukemia, Chronic Myeloid\|Myelodysplastic Syndromes\|Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	July 2015	Phase 2
NCT01410747	Astellas Pharma Inc	Lupus Nephritis	April 10, 2007
NCT00880815	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	CD20 Positive\|Chronic Lymphocytic Leukemia\|Follicular Lymphoma\|Mantle Cell Lymphoma\|Marginal Zone Lymphoma\|Recurrent Diffuse Large B-Cell Lymphoma\|T-Cell Non-Hodgkin Lymphoma	February 17, 2009	Phase 1
NCT00777933	Samsung Medical Center	Kidney Transplantation\|Living Donors	July 2000	Not Applicable
NCT03531281	City of Hope Medical Center\|National Cancer Institute (NCI)	Hematopoietic and Lymphoid Cell Neoplasm\|Hematopoietic Cell Transplantation Recipient	December 30, 2018	Phase 1
NCT00818194	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Healthy	April 2008	Phase 1
NCT00087581	Hoffmann-La Roche	Kidney Transplantation	June 2004	Phase 4
NCT00464555	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Type 1 Diabetes Mellitus	December 2006	Phase 2
NCT01410162	Norman Muirhead\|Astellas Pharma Canada, Inc.\|Lawson Health Research Institute	Renal Transplant\|Kidney Pancreas Transplant	December 2010	Phase 4
NCT00384137	Astellas Pharma Inc	Transplantation	October 2006	Phase 3
NCT00236106	Children´s Clinic, Randers	Atopic Dermatitis	February 2005	Phase 4
NCT00036153	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Rheumatoid Arthritis	March 2002	Phase 3
NCT01206569	Chinese University of Hong Kong	Lupus Nephritis	September 2010	Phase 4
NCT02334488	Poitiers University Hospital	Chronic Kidney Disease	December 11, 2014	Phase 3
NCT02917096	City of Hope Medical Center\|National Cancer Institute (NCI)	Primary Myelofibrosis\|Secondary Myelofibrosis	November 13, 2016	Phase 1
NCT00544115	City of Hope Medical Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Precancerous+Nonmalignant Condition	October 16, 2001	Phase 2
NCT00881556	Columbia University	Epidermolysis Bullosa	August 20, 2009	Early Phase 1
NCT03856216	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia\|Lymphocytic Neoplasm\|Lymphoma	October 28, 2019	Phase 2
NCT02961608	Hospital Universitari de Bellvitge	Kidney Transplant; Complications	May 2016	Phase 4
NCT00615173	Sun Yat-sen University	Kidney Diseases\|Lupus Nephritis\|Tacrolimus\|Induction Phase\|Maintenance Phase	July 2006	Phase 3
NCT04237246	University of Manitoba	Liver Failure	April 2015	Phase 4
NCT03121014	University of Illinois at Chicago	Acute Myeloid Leukemia\|Myelodysplastic Syndromes	April 24, 2017	Phase 2
NCT01418131	The University of Western Australia\|Royal Brisbane and Women´s Hospital\|Royal Adelaide Hospital, Australia\|Liverpool Hospital, Australia\|Fremantle Hospital and Health Service	Ulcerative Colitis	October 2012	Phase 4
NCT01476488	Seoul National University Hospital	Kidney Transplantation\|Pediatric Patients\|Maintenance With Tacrolimus	July 2011	Phase 2\|Phase 3
NCT02496494	Kyungpook National University Hospital	CYCLOSPORINE+TACROLIMUS	September 2012	Phase 4
NCT04747080	Peking University People´s Hospital\|Beijing Hospital\|Beijing Friendship Hospital\|China-Japan Friendship Hospital\|The First Affiliated Hospital of Zhengzhou University\|First Affiliated Hospital of Chongqing Medical University\|Shanxi Bethune hospital, Shanxi, China	ITP\|Immune Thrombocytopenia	March 1, 2021	Phase 2
NCT05252754	Johns Hopkins University	Post-ERCP Acute Pancreatitis	December 1, 2022	Phase 3
NCT03171831	First Affiliated Hospital of Guangxi Medical University	Thalassemia Major	April 1, 2017	Phase 4
NCT01664910	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Hematopoietic and Lymphoid Cell Neoplasm	October 29, 2012	Phase 1\|Phase 2
NCT00919503	Fred Hutchinson Cancer Center\|medac GmbH\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Non-Neoplastic Hematologic and Lymphocytic Disorder	July 31, 2009	Phase 2
NCT01655563	The Hospital for Sick Children	Heart Transplantation\|Liver Transplantation\|Kidney Transplantation	September 2011	Phase 2
NCT00629122	Weill Medical College of Cornell University	Kidney Failure, Chronic	February 2008	Phase 4
NCT02120157	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Myeloablative Conditioning\|HLA-mismatched Bone Marrow Transplantation\|Graft Survival\|Transplantation, Bone Marrow	July 2, 2015	Phase 2
NCT02123108	University of California, Los Angeles\|Novartis	Liver Transplantation	January 2011	Phase 4
NCT02663622	OncoImmune, Inc.\|Ohio State University\|University of Michigan Rogel Cancer Center\|Indiana University School of Medicine\|Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Hematopoietic Stem Cell Transplantation\|Leukemia	September 19, 2016	Phase 2
NCT03864250	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	Tacrolimus\|Idiopathic Membranous Nephropathy\|Clinical Trial	November 26, 2018	Not Applicable
NCT02217410	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation	February 5, 2015	Phase 1\|Phase 2
NCT04102943	Chong Kun Dang Pharmaceutical	Kidney Transplant	November 30, 2017	Phase 4
NCT00536978	M.D. Anderson Cancer Center	Lymphoma\|Leukemia	September 2007	Phase 2
NCT05589896	Ossium Health, Inc.\|Center for International Blood and Marrow Transplant Research	Acute Leukemia\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Biphenotypic Leukemia\|Acute Undifferentiated Leukemia	March 2023	Phase 1\|Phase 2
NCT00965094	Novartis Pharmaceuticals\|Novartis	Chronic Renal Failure	December 2009	Phase 4
NCT04127721	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Allogeneic Stem Cell Transplant Recipient\|Hematologic and Lymphocytic Disorder\|Hematopoietic and Lymphoid Cell Neoplasm	September 22, 2020	Phase 2
NCT04384692	Fred Hutchinson Cancer Center	Primary Myelofibrosis\|Secondary Myelofibrosis	December 18, 2020	Phase 2
NCT00149994	Novartis Pharmaceuticals\|Novartis	Liver Transplant	December 2002	Phase 4
NCT04768465	Da, Yuwei, M.D.	Myasthenia Gravis	January 1, 2021
NCT04904588	Center for International Blood and Marrow Transplant Research\|National Marrow Donor Program	Acute Lymphoblastic Leukemia\|Acute Myelogenous Leukemia\|Mixed Phenotype Acute Leukemia\|Acute Leukemia\|Myelodysplastic Syndromes\|Chronic Myelogenous Leukemia\|Chronic Lymphocytic Leukemia\|Lymphoma	September 30, 2021	Phase 2
NCT00189826	Astellas Pharma Inc	Liver Transplantation	August 2004	Phase 3
NCT02084446	Ronaldo de Matos Esmeraldo, MD\|Novartis Pharmaceuticals\|Hospital Geral de Fortaleza	Transplantation Infection\|Cytomegalovirus Infections	December 2012	Phase 4
NCT00622869	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	January 2008	Phase 3
NCT00443508	Rabin Medical Center\|Novartis	Kidney Diseases	February 2007	Phase 4
NCT00118742	Hoffmann-La Roche	Liver Transplantation	August 2005	Phase 4
NCT05202145	Alexion Pharmaceuticals	Healthy	January 11, 2022	Phase 1
NCT01858740	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Refractory Adult Acute Lymphoblastic Leukemia\|Refractory Childhood Acute Lymphoblastic Leukemia	December 17, 2013	Phase 2
NCT00950391	Washington University School of Medicine	Peripheral Nerve Injury	August 2010	Phase 1\|Phase 2
NCT00912678	University of Luebeck\|Astellas Pharma GmbH	Kidney Transplantation	March 2002	Phase 4
NCT01292525	Nantes University Hospital	Function of Renal Transplant	May 2011	Phase 3
NCT02954159	Medical College of Wisconsin\|Takeda	Ulcerative Colitis	May 18, 2017	Phase 3
NCT05156710	Sanofi	Transplant Rejection	June 9, 2022	Phase 2
NCT01092806	University of Oslo School of Pharmacy\|Oslo University Hospital	Post Transplant Diabetes Mellitus	October 2009	Phase 4
NCT01116232	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Lymphoproliferative Disorder\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	August 2010	Phase 2
NCT00350545	Stanford University	Graft vs Host Disease	August 2006	Not Applicable
NCT00006350	University of Maryland, Baltimore	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	January 2000	Phase 2
NCT00134394	University of Medicine and Dentistry of New Jersey\|Rutgers, The State University of New Jersey	Psoriasis	February 2005	Phase 2
NCT01224041	Astellas Pharma Inc\|Astellas Pharma Korea, Inc.	Rheumatoid Arthritis	August 2009	Phase 4
NCT02711202	Institute for Clinical and Experimental Medicine\|Charite University, Berlin, Germany\|Miltenyi Biomedicine GmbH	Kidney Transplantation	January 2007	Not Applicable
NCT01080469	Panacea Biotec Ltd	Healthy Volunteers	September 2007	Not Applicable
NCT00319917	Astellas Pharma Inc	Rheumatoid Arthritis	April 2006	Phase 4
NCT00004255	Chimeric Therapies\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	March 2000	Phase 2\|Phase 3
NCT05396898	University Hospital Tuebingen	Posttransplant Diabetes Mellitus	December 16, 2020	Phase 4
NCT01570348	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Institutes of Health (NIH)	Crohn Disease	July 17, 2012	Phase 2
NCT00402168	Bristol-Myers Squibb	Renal Transplant	January 2007	Phase 2
NCT00321113	Astellas Pharma Inc	KIDNEY TRANSPLANTATION	September 2004	Phase 3
NCT00519116	Wyeth is now a wholly owned subsidiary of Pfizer	Kidney Transplantation	October 2000	Phase 4
NCT00014469	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	December 2000	Phase 2
NCT03118492	City of Hope Medical Center\|National Cancer Institute (NCI)	Secondary Myelofibrosis	May 24, 2017	Phase 1
NCT02016625	Boehringer Ingelheim	Healthy	December 2013	Phase 1
NCT01049633	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Type 1 Diabetes Mellitus
NCT00670423	Jennifer E. Schwartz\|Millennium Pharmaceuticals, Inc.\|Indiana University	Graft vs Host Disease\|Peripheral Blood Stem Cell Transplantation\|Transplantation, Homologous	May 16, 2008	Phase 1
NCT02435901	Northwell Health	Sickle Cell Disease\|Beta Thalassemia-Major	December 2008	Phase 1\|Phase 2
NCT00578903	Baylor College of Medicine\|The Methodist Hospital Research Institute\|Center for Cell and Gene Therapy, Baylor College of Medicine	Aplastic Anemia	February 2002	Phase 2
NCT02683291	Associação Médico Espírita de Botucatu	Disorder Related to Renal Transplantation\|Cytomegalovirus Infections	January 2014	Phase 4
NCT03292861	Cedars-Sinai Medical Center\|Genzyme, a Sanofi Company	Heart Transplantation	September 13, 2018	Phase 2
NCT00459719	Astellas Pharma Inc	Liver Transplantation	March 2007	Phase 3
NCT00141037	National Institute of Allergy and Infectious Diseases (NIAID)\|Astellas Pharma Inc\|Hoffmann-La Roche	Kidney Diseases\|Kidney Transplantation\|Kidney Transplant\|Renal Transplantation\|Renal Transplant	March 2004	Phase 1\|Phase 2
NCT04360031	Université Catholique de Louvain	Kidney Transplant; Complications\|Immunosuppression\|Transplant Failure	February 10, 2020
NCT00498316	M.D. Anderson Cancer Center\|ViaCell\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Myelodysplastic Syndrome\|Leukemia	July 3, 2007	Phase 1
NCT05001074	Heleen Grootjans\|Chiesi Farmaceutici S.p.A.\|University Medical Center Groningen	Lung Transplant; Complications	July 28, 2020	Phase 3
NCT00270634	Aurinia Pharmaceuticals Inc.	Kidney Diseases	January 2006	Phase 2
NCT00295594	Astellas Pharma Inc	Liver Transplantation	March 2005	Phase 3
NCT04720326	Edward Geissler\|Chiesi GmbH\|Excelya Germany GmbH\|University of Regensburg	Prophylaxis Against Liver Transplant Rejection	December 23, 2020	Phase 4
NCT02224872	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Severe Aplastic Anemia\|Bone Marrow Failure Syndromes	August 2014	Phase 2
NCT00666302	Astellas Pharma Inc	Dermatitis, Atopic	October 2002	Phase 4
NCT01162005	Seoul National University Hospital\|Chong Kun Dang Pharmaceutical	Nephrotic Syndrome	July 2010	Phase 4
NCT01652014	University of Medicine and Dentistry of New Jersey\|National Cancer Institute (NCI)\|Rutgers, The State University of New Jersey	Accelerated Phase Chronic Myelogenous Leukemia\|Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Waldenström Macroglobulinemia	January 2014	Phase 2
NCT03467386	City of Hope Medical Center\|National Cancer Institute (NCI)	Acute Myeloid Leukemia	March 19, 2018	Phase 1
NCT00567918	Astellas Pharma Inc	Keratoconjunctivitis\|Conjunctivitis	May 2004	Phase 3
NCT02706678	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Renal Transplant Recipients	December 29, 2010	Phase 4
NCT00160966	University of Giessen\|Heidelberg University\|Hoffmann-La Roche\|Astellas Pharma Inc\|Novartis	Polyomavirus Infections	September 2004	Phase 4
NCT04311632	ITB-Med LLC	Kidney Transplantation	May 26, 2021	Phase 2
NCT01294020	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Intestine Transplantation\|Kidney Transplantation\|Lung Transplantation\|Liver Transplantation\|Heart Transplantation	May 25, 2011	Phase 2
NCT01325571	Astellas Pharma Inc\|Astellas Pharma China, Inc.	Myasthenia Gravis	March 2011	Phase 3
NCT00429416	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematologic Malignancies	March 2004	Phase 1\|Phase 2
NCT02122081	Ohio State University Comprehensive Cancer Center	Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia	July 27, 2015	Not Applicable
NCT00621699	University Medicine Greifswald	Pharmacokinetics\|Drug Interactions\|Hypercholesterolemia\|Immunosuppression	September 2007	Phase 1
NCT04022239	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Hematopoietic and Lymphoid System Neoplasm	March 13, 2020	Phase 1\|Phase 2
NCT00086346	Wyeth is now a wholly owned subsidiary of Pfizer	Liver Transplantation	December 2002	Phase 3
NCT05115630	M.D. Anderson Cancer Center	Myeloid Malignancies\|Acute Myeloid Leukemia\|Myelodysplastic Syndrome\|Chronic Myeloid Leukemia	April 8, 2022	Phase 1\|Phase 2
NCT03527238	University of Florida\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Liver Transplant\|Kidney Transplant	September 21, 2018	Phase 2
NCT02333162	University of Chicago\|National Cancer Institute (NCI)	Previously Treated Myelodysplastic Syndrome\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Hematologic Malignancy	December 5, 2014	Phase 1
NCT01334333	University of British Columbia\|Simon Fraser University\|Astellas Pharma Canada, Inc.	Renal Disease\|Renal Transplant	November 11, 2011	Phase 4
NCT00463723	University Hospital Freiburg\|Sucampo Pharmaceuticals, Inc.	Penetrating Keratoplasty		Phase 2\|Phase 3
NCT02495077	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation\|Rho Federal Systems Division, Inc.	Kidney Transplant	November 2, 2015	Phase 2
NCT01702181	Otsuka Pharmaceutical Development & Commercialization, Inc.	Atopic Dermatitis	August 2012	Phase 1
NCT03426969	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Primary Myelofibrosis\|Secondary Myelofibrosis	January 31, 2018	Early Phase 1
NCT00374231	University of Cincinnati\|Astellas Pharma Inc	Liver Transplantation	October 2002	Phase 4
NCT00144703	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital	Hematologic Malignancies\|Myelogenous Leukemia\|Acute Lymphoblastic Leukemia\|Myelodysplastic Syndrome\|Non-Hodgkin´s Lymphoma\|Hodgkin´s Disease	July 2002	Phase 2
NCT00325325	Hospital Universitario Ramon y Cajal\|Novartis\|Astellas Pharma Inc	Kidney Diseases	January 2006	Phase 2
NCT01647945	Edda Spiekerkoetter\|Stanford University	Pulmonary Arterial Hypertension	July 2012	Phase 2
NCT04936282	Fundación Canaria de Investigación Sanitaria	Kidney Transplant Failure and Rejection	January 2022	Phase 4
NCT00617604	Astellas Pharma Inc	De Novo Kidney Transplantation	December 2007	Phase 2
NCT00807144	Imperial College Healthcare NHS Trust	End-stage Renal Failure\|Graft Rejection	December 2008	Phase 4
NCT03415750	Edoardo Melilli\|Hospital Universitari de Bellvitge	Hypertrophy, Left Ventricular	November 2016	Phase 4
NCT00317785	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	May 2005	Phase 2
NCT00053989	Roswell Park Cancer Institute	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Fanconi Anemia\|Aplastic Anemia	January 29, 2002	Phase 2
NCT01763580	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	MCNS\|Minimal Change Nephrotic Syndrome (MCNS)	July 16, 2012	Phase 4
NCT02918292	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)\|Blood and Marrow Transplant Clinical Trials Network\|National Marrow Donor Program	Severe Aplastic Anemia	July 3, 2017	Phase 2
NCT01529827	Roswell Park Cancer Institute	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Aplastic Anemia\|Burkitt Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Congenital Amegakaryocytic Thrombocytopenia\|Diamond-Blackfan Anemia\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Paroxysmal Nocturnal Hemoglobinuria\|Peripheral T-cell Lymphoma\|Polycythemia Vera\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Secondary Myelofibrosis\|Severe Combined Immunodeficiency\|Severe Congenital Neutropenia\|Shwachman-Diamond Syndrome\|Splenic Marginal Zone Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Waldenstrom Macroglobulinemia\|Wiskott-Aldrich Syndrome	February 28, 2012	Phase 2
NCT03480360	Dartmouth-Hitchcock Medical Center	Acute Myeloid Leukemia\|Chronic Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Myelodysplasia\|Myeloproliferative Disorder\|Myelofibrosis\|Lymphoma\|Lymphoma, Non-Hodgkin\|Plasma Cell Disorder	March 28, 2018	Phase 3
NCT00533442	University of Miami\|Astellas Pharma Inc	Type 1 Diabetes	September 2000	Phase 2
NCT01904045	Technical University of Munich	Immunosuppression After Kidney Transplantation	May 2013
NCT03640026	Centre Hospitalier Departemental Vendee	Kidney Failure, Chronic	March 8, 2019	Phase 4
NCT03816332	National Cancer Institute (NCI)	Clinical Stage III Cutaneous Melanoma AJCC v8\|Clinical Stage III Merkel Cell Carcinoma AJCC v8\|Clinical Stage IV Cutaneous Melanoma AJCC v8\|Clinical Stage IV Merkel Cell Carcinoma AJCC v8\|Metastatic Basal Cell Carcinoma\|Metastatic Melanoma\|Metastatic Merkel Cell Carcinoma\|Metastatic Skin Squamous Cell Carcinoma\|Pathologic Stage III Cutaneous Melanoma AJCC v8\|Pathologic Stage III Merkel Cell Carcinoma AJCC v8\|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8\|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8\|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8\|Pathologic Stage IIID Cutaneous Melanoma AJCC v8\|Pathologic Stage IV Cutaneous Melanoma AJCC v8\|Pathologic Stage IV Merkel Cell Carcinoma AJCC v8\|Unresectable Basal Cell Carcinoma\|Unresectable Melanoma\|Unresectable Merkel Cell Carcinoma	February 1, 2019	Phase 1
NCT00650468	Astellas Pharma Inc	Renal Transplantation	November 1999	Phase 4
NCT00166816	National Taiwan University Hospital	Transplantation\|Kidney Transplantation\|Immunosuppression	March 2002	Phase 4
NCT04810156	Inge Marie Svane\|Herlev Hospital	Hepatitis, Drug-Induced	April 7, 2021	Phase 2
NCT01084980	Seoul National University Hospital	Minimal Change Disease	June 2010	Phase 2\|Phase 3
NCT04267991	Benha University	Corneal Disease	April 1, 2018
NCT00439556	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	CD20 Positive\|Hematopoietic and Lymphoid Cell Neoplasm\|Lymphocytic Neoplasm\|Lymphoma	February 13, 2007	Phase 2
NCT00385788	M.D. Anderson Cancer Center	Hodgkin´s Disease	July 2005	Phase 2
NCT00637143	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Renal Transplantation\|Chronic Renal Allograft Failure	April 1999	Phase 4
NCT00281879	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Unusual Cancers of Childhood	February 2006	Phase 2
NCT04440371	Jordan University of Science and Technology	Vitiligo, Generalized	June 21, 2020	Not Applicable
NCT02199041	St. Jude Children´s Research Hospital	Hematological Malignancies	July 11, 2014	Phase 2
NCT00025519	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Kidney Cancer	June 2001	Phase 2
NCT00296361	Astellas Pharma Inc	Kidney Transplantation	October 2004	Phase 3
NCT05073822	University College, London	Renal Transplant Rejection\|Renal Transplant Infection	February 20, 2023	Phase 1\|Phase 2
NCT03178149	Astellas Institute for Regenerative Medicine\|Astellas Pharma Inc	Age-Related Macular Degeneration	July 13, 2018	Phase 1
NCT00297310	Janssen-Cilag Pty Ltd	Kidney Transplantation\|Transplantation	May 2004	Phase 4
NCT01060475	Limerick BioPharma	Healthy	February 2010	Phase 1
NCT01614665	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Heart Transplantation\|Kidney Transplantation\|Liver Transplantation	April 3, 2012	Phase 2
NCT01161459	Zhi-Hong Liu, M.D.\|Nanjing University School of Medicine	Idiopathic Membranous Nephropathy	June 2010	Not Applicable
NCT00384202	Astellas Pharma Inc	Transplantation	October 2006	Phase 3
NCT03791827	Xiqiang Dang\|The Children´s Hospital Affiliated to Suzhou University\|Shandong Provincial Hospital\|Guizhou Provincial People´s Hospital\|LanZhou University\|The First Affiliated Hospital of Inner Mongolia Medical College\|People´s Hospital of Zhangjiajie\|Puyang Oilfield General Hospital\|The First Affiliated Hospital of Anhui Medical University\|Guizhou Maternal and Child Health Care Hospital\|The Second Affiliated Hospital & Yuying Children´s Hospital of Wenzhou Medical University\|Shenzhen Children´s Hospital\|The Second Affiliated Hospital of Harbin Medical University\|Yichang Central People´s Hospital\|Xian Children´s Hospital\|Wuhan Children´s Hospital, Tongji Medical College, Huazhong University of Science & Technology\|The First People´s Hospital of Yunnan\|The First Affiliated Hospital of Xiamen University\|The First Affiliated Hospital of Xinxiang Medical College\|Shanxi Provincial Maternity and Children´s Hospital\|Liaocheng People´s Hospital\|Fujian Provincial Hospital\|First Affiliated Hospital of Guangxi Medical University\|Second Hospital of Lanzhou University\|Guangzhou First People´s Hospital\|The Second Hospital of Shandong University\|Children´s Hospital of Hebei Province\|Beijing Children´s Hospital\|Zhengzhou Children´s Hospital\|The Children´s Hospital of Chongqing Medical University\|Wuxi Children´s Hospital\|The Children´s Hospital of Fudan University\|Shanghai Children´s Medical Center\|Qilu Children´s Hospital of Shandong University\|Second Xiangya Hospital of Central South University	Lupus Nephritis\|Children\|Steroid\|Immunosuppressive Treatment	December 1, 2018
NCT03020589	University of North Carolina, Chapel Hill	Renal Transplant	February 6, 2017	Phase 4
NCT01309022	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Diabetes Mellitus, Type 1
NCT01598987	Novartis Pharmaceuticals\|Novartis	Renal Function\|Liver Transplant	October 2012	Phase 3
NCT03842696	University of Michigan Rogel Cancer Center\|National Institutes of Health (NIH)	Hematologic Diseases\|Acute Leukemia in Remission\|Chronic Myelogenous Leukemia - Chronic Phase\|Chronic Myelogenous Leukemia, Accelerated Phase\|Chronic Myelogenous Leukemia, Blastic Phase\|Myelodysplastic Syndromes\|Mantle Cell Lymphoma\|Follicular Lymphoma\|Diffuse Large B Cell Lymphoma\|Non Hodgkin Lymphoma\|Graft Vs Host Disease\|Graft-versus-host-disease	February 4, 2020	Phase 1\|Phase 2
NCT02723591	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	Kidney Transplantation	September 9, 2016	Phase 4
NCT04341038	Hospital Universitari de Bellvitge\|Institut d´Investigació Biomèdica de Bellvitge	COVID-19\|Lung Injury	April 1, 2020	Phase 3
NCT04645667	UNC Lineberger Comprehensive Cancer Center\|University of North Carolina, Chapel Hill	Acute GVHD	February 1, 2021
NCT02081755	Baylor Research Institute	Carcinoma, Hepatocellular	March 2014	Phase 4
NCT01958190	Foundation for Liver Research	Liver Disease	February 7, 2011	Phase 4
NCT01082393	University Hospital, Ghent	Vitiligo	February 2010	Phase 4
NCT01371331	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Kidney Transplantation\|Heart Transplantation\|Liver Transplantation	June 9, 2011	Phase 4
NCT00514982	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Hermanski-Pudlak Syndrome\|Colitis\|Cytokines\|Lymphocytes\|Drug Evaluation	August 7, 2007	Phase 2
NCT00282256	Astellas Pharma Inc	Liver Transplantation	January 2004	Phase 2
NCT01080534	Panacea Biotec Ltd	Healthy Volunteers	September 2007	Not Applicable
NCT02953873	Medical University of South Carolina\|Astellas Pharma Inc	Immunosuppression	May 5, 2017	Phase 4
NCT01268995	Medical University of Vienna	New Onset Diabetes Mellitus After Renal Transplantation	September 2009	Phase 2
NCT02328755	University of Michigan Rogel Cancer Center	Acute Myeloid Leukemia	January 2015	Phase 1\|Phase 2
NCT00203281	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Kidney Transplantation\|Plasmapheresis	February 2003
NCT05607901	Tanta University	Dermatologic Disease	October 28, 2022	Phase 2
NCT04877288	Bristol-Myers Squibb	Renal Allograft Recipients	July 21, 2021	Phase 3
NCT00302523	Nanjing University School of Medicine	Idiopathic Membranous Nephropathy	March 2006	Not Applicable
NCT01323920	Dana-Farber Cancer Institute	Leukemia\|Lymphoma\|Myelodysplastic Syndrome	May 2011	Phase 2
NCT04147390	Shahid Beheshti University of Medical Sciences	Keratopathy	November 2019	Phase 2\|Phase 3
NCT02588339	H. Lee Moffitt Cancer Center and Research Institute\|Novartis	Graft Versus Host Disease\|GVHD	March 4, 2016	Phase 2
NCT03315052	Montefiore Medical Center	Acute Cellular Graft Rejection\|Liver Transplant Rejection	January 2019	Phase 4
NCT00801632	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Kidney Transplantation\|Kidney Failure, Chronic	December 2008	Phase 2
NCT00402558	M.D. Anderson Cancer Center	Myelodysplastic Syndrome\|Leukemia	May 2006	Phase 1
NCT03760263	Sentara Norfolk General Hospital\|Veloxis Pharmaceuticals	Transplant;Failure,Kidney	January 16, 2020	Phase 4
NCT01354301	Hospital do Rim e Hipertensão	Cytomegalovirus Infection\|Renal Transplant Failure\|Transplant; Complication, Rejection	May 2011	Phase 4
NCT01870908	Astellas Pharma Inc	Rheumatoid Arthritis	August 2012
NCT04629248	Hoffmann-La Roche	Primary Membranous Nephropathy	June 25, 2021	Phase 3
NCT03249831	City of Hope Medical Center\|California Institute for Regenerative Medicine (CIRM)	Sickle Cell Disease\|Sickle Cell Disorder\|Hemoglobinopathies\|Thalassemia\|Anemia, Sickle Cell	January 4, 2019	Phase 1
NCT02782546	Washington University School of Medicine\|National Institutes of Health (NIH)\|The V Foundation for Cancer Research\|National Cancer Institute (NCI)\|ImmunityBio, Inc.	Acute Myeloid Leukemia	January 30, 2017	Phase 2
NCT00818961	Northside Hospital, Inc.\|Blood and Marrow Transplant Group of Georgia	Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	May 2005	Phase 2
NCT00261820	Wyeth is now a wholly owned subsidiary of Pfizer	Graft Rejection\|Kidney Failure\|Kidney Transplantation		Phase 4
NCT01702207	University of Saskatchewan\|Astellas Pharma Canada, Inc.	Immunosuppression\|Cardiovascular Diseases\|Kidney Transplantation	October 2012	Phase 4
NCT03465410	NURIA LLOBERAS BLANCH\|Hospital Universitari de Bellvitge	KIDNEY TRANSPLANTATION	March 21, 2017	Phase 4
NCT00005113	Boston Children´s Hospital	End-Stage Renal Disease\|Kidney Transplantation	July 1999	Phase 3
NCT04498741	Enanta Pharmaceuticals, Inc\|Pharmaceutical Research Associates	RSV Infection	July 8, 2020	Phase 1
NCT01473732	Montefiore Medical Center	Chronic Allograft Injury\|Calcineurin Inhibitor Toxicity	March 2012	Not Applicable
NCT01159080	Asan Medical Center\|Seoul National University Hospital\|Samsung Medical Center	Kidney Transplantation	April 1, 2010	Phase 4
NCT02837978	Qiang Shu\|Qilu Hospital of Shandong University	Arthritis, Rheumatoid	January 2015	Phase 4
NCT02206035	William R. Drobyski, MD\|Medical College of Wisconsin	Hematopoietic Stem Cell Transplantation	December 2014	Phase 2
NCT01850979	University of Sao Paulo General Hospital	Sjogren Syndrome\|Dry Eye Syndrome	February 2010	Phase 4
NCT00833079	Taro Pharmaceuticals USA	Atopic Dermatitis	October 2008	Phase 1
NCT00448357	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)\|Otsuka America Pharmaceutical	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	October 2005	Phase 1\|Phase 2
NCT00038948	Wyeth is now a wholly owned subsidiary of Pfizer	Renal Transplantation	January 2002	Phase 3
NCT00299221	Newark Beth Israel Medical Center\|Astellas Pharma Inc	Immunosuppression	April 2004	Phase 4
NCT04917718	Loyola University\|Veloxis Pharmaceuticals	Chronic Kidney Diseases\|Heart Transplant	August 16, 2021	Phase 4
NCT00504348	Tokyo Medical and Dental University\|Japan Medical Association\|Astellas Pharma Inc	Interstitial Pneumonitis\|Polymyositis\|Dermatomyositis	July 2007	Phase 2\|Phase 3
NCT01938625	Janssen R&D Ireland	Hepatitis C, Chronic	December 12, 2013	Phase 2
NCT01128335	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	April 2010	Phase 2
NCT01713400	H. Lee Moffitt Cancer Center and Research Institute\|Gateway for Cancer Research	Graft vs. Host Disease	February 25, 2013	Phase 2
NCT03062813	Guangdong Provincial People´s Hospital	Hepatitis B Virus Associated Nephrotic Syndrome	February 1, 2017	Phase 4
NCT00499889	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia	February 2003	Phase 2
NCT00890500	Fate Therapeutics\|Dana-Farber Cancer Institute	Hematologic Malignancies\|Allogeneic Stem Cell Transplantation	January 2011	Phase 1
NCT01807767	Medical College of Wisconsin	High Model for End-Stage Liver Disease (MELD) Score	March 2013	Not Applicable
NCT01789619	UMC Utrecht	Atopic Dermatitis	October 2012
NCT01120028	University of Oxford\|National Health Service, United Kingdom\|Pfizer\|Novartis	Kidney Transplantation	September 2010	Phase 2\|Phase 3
NCT00448201	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	January 7, 2011	Phase 2
NCT05031897	Thomas Jefferson University	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Aplastic Anemia\|Chronic Lymphocytic Leukemia\|Chronic Myelomonocytic Leukemia\|Essential Thrombocythemia\|Hematopoietic and Lymphoid Cell Neoplasm\|Hodgkin Lymphoma\|Myelodysplastic Syndromes\|Myelofibrosis\|Myeloid Leukemia\|Myeloid Neoplasm\|Non-Hodgkin Lymphoma\|Plasma Cell Myeloma\|Polycythemia Vera\|Small Lymphocytic Lymphoma	October 25, 2021	Phase 2
NCT00109993	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Breast Cancer\|Chronic Myeloproliferative Disorders\|Gestational Trophoblastic Tumor\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Neuroblastoma\|Ovarian Cancer\|Testicular Germ Cell Tumor	January 2005	Phase 2
NCT05293509	M.D. Anderson Cancer Center	Stem Cell Transplantation	September 30, 2022	Phase 2
NCT01430065	Astellas Pharma Inc	Pharmacokinetics of ASP015K\|Drug Interactions\|Healthy Subjects	June 2009	Phase 1
NCT05089604	University of British Columbia\|Paladin Labs Inc.	Liver Transplantation\|Immunosuppression\|Neurotoxicity\|Tremor\|Tacrolimus	December 2021	Phase 4
NCT00895583	Pfizer	Graft Rejection\|Kidney Transplant\|Renal Allograft Recipients\|Renal Transplant	June 2009	Phase 4
NCT02630628	The University of Hong Kong	Lupus Nephritis	December 5, 2015	Phase 4
NCT03277430	Institute for Clinical and Experimental Medicine\|University Hospital, Motol\|Sahlgrenska University Hospital, Sweden	Mayer Rokitansky Kuster Hauser Syndrome\|Mullerian Aplasia\|Uterus; Absence, Congenital\|Infertility, Female\|Uterus Absence, Acquired\|Absolute Uterine Factor Infertility	October 9, 2015	Phase 3
NCT02582775	Masonic Cancer Center, University of Minnesota	Epidermolysis Bullosa	March 2016	Phase 2
NCT02504359	OHSU Knight Cancer Institute\|Oregon Health and Science University	Plasma Cell Leukemia\|Recurrent Plasma Cell Myeloma	July 20, 2015	Phase 1
NCT00031824	Children´s Oncology Group\|National Cancer Institute (NCI)	Graft Versus Host Disease	April 2002	Phase 3
NCT00669890	New York Medical College	Acute Myeloid Leukemia\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic Syndrome	May 2004	Phase 1
NCT03437577	University of Minnesota	Kidney Transplant Failure and Rejection	May 8, 2018	Phase 1\|Phase 2
NCT04156204	University of Colorado, Denver	Kidney Transplant Rejection\|Medication Adherence	November 20, 2019	Early Phase 1
NCT01911546	Joseph Kahwaji, MD, MPH\|Novartis\|Cedars-Sinai Medical Center	Highly-sensitized Kidney Transplant Recipients	June 2013	Phase 2
NCT05324618	Ain Shams University\|National Hepatology & Tropical Medicine Research Institute	Atopic\|Dermatitis	April 15, 2022	Phase 4
NCT00278512	Northwestern University	Vasculitis	August 2003	Phase 1
NCT01802268	Helio Tedesco Silva Junior\|Pfizer\|Hospital do Rim e Hipertensão	Kidney Transplant	February 2008	Phase 4
NCT00896012	University at Buffalo\|Novartis\|University of Washington	Kidney Transplantation	January 2008	Phase 4
NCT02752529	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	Cirrhosis, Liver	March 2016	Not Applicable
NCT00346359	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	March 2006	Phase 2
NCT04725682	Food and Drug Administration (FDA)\|BioPharma Services USA	Healthy Volunteers	January 5, 2021	Phase 1
NCT00803010	H. Lee Moffitt Cancer Center and Research Institute	Acute Graft Versus Host Disease	September 2008	Phase 2
NCT00284934	Novartis	Kidney Diseases	December 2005	Phase 3
NCT00134004	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	October 2004	Phase 2
NCT00693381	Astellas Pharma Inc	Kidney Transplantation	February 2003	Phase 3
NCT03770663	Assistance Publique - Hôpitaux de Paris	Antisynthetase Syndrome (ASS)\|Interstitial Lung Disease	February 5, 2021	Phase 3
NCT03797196	University Medical Center Groningen\|Radboud University Medical Center\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Amsterdam UMC, location VUmc\|UMC Utrecht\|Leiden University Medical Center\|Erasmus Medical Center\|Universitaire Ziekenhuizen KU Leuven	Renal Transplant Recipients\|Elderly Patients\|Immunosuppression	July 29, 2019	Phase 4
NCT04225988	Cedars-Sinai Medical Center\|Veloxis Pharmaceuticals	Kidney Transplant Rejection	January 9, 2020	Phase 4
NCT00423826	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Precancerous Condition\|Secondary Myelofibrosis	January 2007
NCT00133172	Astellas Pharma Inc\|Astellas Pharma Canada, Inc.	Kidney Transplantation	July 2005	Phase 4
NCT00133367	Massachusetts General Hospital\|Dana-Farber Cancer Institute	Multiple Myeloma\|Non-Hodgkin´s Lymphoma\|Hodgkin´s Disease\|Myelogenous Leukemia\|Lymphoblastic Leukemia	August 2005	Phase 2
NCT00555321	Bristol-Myers Squibb	Immunosuppression in Solid Organ Transplant	January 2008	Phase 2
NCT00313625	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Multiple Myeloma and Plasma Cell Neoplasm	September 2005	Phase 2
NCT02147938	Astellas Pharma S.A.S.\|Astellas Pharma Inc	Renal Transplantation	July 17, 2014
NCT04444817	University Hospital Heidelberg	Liver Transplantation	November 22, 2018
NCT01532635	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematologic Malignancy\|Leukemia\|Acute Lymphoblastic Leukemia\|ALL\|Acute Myelogenous Leukemia\|AML\|Chronic Lymphocytic Leukemia\|CLL\|Lymphoma\|Hodgkin´s Lymphoma\|Non-hodgkin´s Lymphoma\|Myeloma	March 2012	Phase 2
NCT00946023	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Lymphoma\|B-cell Lymphoma\|Non Hodgkin Lymphoma\|Chronic Lymphocytic Leukemia	July 2009	Phase 2
NCT03321656	Roberto Gedaly\|Veloxis Pharmaceuticals\|University of Kentucky	End Stage Renal Disease	March 28, 2019	Phase 2\|Phase 3
NCT03713645	Temple University\|Veloxis Pharmaceuticals	Kidney Transplant	November 12, 2018	Phase 4
NCT01885689	City of Hope Medical Center\|National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Adult Acute Myeloid Leukemia in Remission\|Myelodysplastic Syndrome\|Secondary Myelodysplastic Syndrome\|Chronic Myelomonocytic Leukemia\|Therapy-Related Myelodysplastic Syndrome	February 10, 2014	Phase 2
NCT00975663	University Hospital, Limoges	Lung and Heart-lung Transplantation	September 2009	Phase 4
NCT00935298	The Second Artillery General Hospital\|Capital Medical University\|Shanghai Changzheng Hospital\|Pharmacology Research Institute\|Air Force General Hospital of the PLA\|Health Department of General Logistics	Renal Transplantation	July 2009	Phase 4
NCT03380936	University of Colorado, Denver\|Veloxis Pharmaceuticals	Kidney Transplant Rejection	January 17, 2018	Early Phase 1
NCT00667056	Astellas Pharma Inc	Dermatitis	July 2004	Phase 4
NCT01342289	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Hodgkin´s Lymphoma\|Leukemia\|Myelodysplastic Syndrome(MDS)\|Multiple Myeloma\|Non Hodgkin´s Lymphoma	August 2011	Phase 1
NCT02921789	Astellas Pharma Global Development, Inc.\|Kyowa Kirin Co., Ltd.\|Astellas Pharma Inc	Kidney Transplantation\|Primary Focal Segmental Glomerulosclerosis (FSGS)	May 22, 2017	Phase 2
NCT04002115	Milton S. Hershey Medical Center	Acute Myeloid Leukemia	June 3, 2020	Phase 2
NCT00151632	Rennes University Hospital\|Ministry of Health, France	Evidence of Liver Transplantation	May 2003	Phase 3
NCT00860574	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	February 2009	Phase 2
NCT01843348	Novartis Pharmaceuticals\|Novartis	Kidney Transplantation\|Renal Transplantation	December 27, 2012	Phase 3
NCT02601703	Glenmark Pharmaceuticals Ltd. India	Atopic Dermatitis	August 2015	Phase 3
NCT01080482	Panacea Biotec Ltd	Healthy Volunteers	September 2007	Not Applicable
NCT00302536	Nanjing University School of Medicine	Focal Glomerulosclerosis	March 2006	Not Applicable
NCT01782729	Janssen-Cilag Ltd.,Thailand	Dermatitis, Atopic	March 2008	Phase 4
NCT00429377	Astellas Pharma Inc	Lupus Nephritis	June 2003	Phase 3
NCT00004904	Northwestern University\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Precancerous+Nonmalignant Condition\|Small Intestine Cancer	October 1999	Phase 1
NCT03779854	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Biphenotypic Leukemia\|Acute Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Lymphoblastic Leukemia\|Acute Undifferentiated Leukemia\|Allogeneic Hematopoietic Stem Cell Transplantation Recipient\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Blasts Under 25 Percent of Bone Marrow Nucleated Cells\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Mixed Phenotype Acute Leukemia\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2	August 29, 2019	Phase 2
NCT00577278	City of Hope Medical Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma	October 3, 2007	Phase 2
NCT04292418	Assiut University	Rejection Acute Renal	May 1, 2020
NCT00116103	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Asthma	June 2005	Phase 2
NCT04590183	Peking University	Posner Schlossman Syndrome	October 1, 2020	Not Applicable
NCT01436305	National Institute of Allergy and Infectious Diseases (NIAID)\|Clinical Trials in Organ Transplantation	Kidney Transplantation\|Renal Transplantation	September 2011	Phase 2
NCT04788641	AstraZeneca\|Parexel	Hyperkalaemia	March 30, 2021	Phase 1
NCT04045171	The Third Xiangya Hospital of Central South University\|Hunan Provincial People´s Hospital\|ZhuZhou Central Hospital\|First People´s Hospital of Chenzhou	Nephrotic Syndrome\|Tacrolimus\|Pharmacokinetics	August 10, 2019
NCT05032248	Assiut University	Oral Ulcer\|Behcet Syndrome	April 1, 2019	Not Applicable
NCT00523952	Astellas Pharma Inc	Dermatitis, Atopic	January 2004	Phase 3
NCT00286871	Duke University\|Novartis Pharmaceuticals	Chronic Hepatitis C\|Organ Transplantation\|Immunosuppression	February 2006	Phase 1
NCT00492661	Janssen-Cilag Pty Ltd	Renal Transplantion\|Kidney Transplantion	July 2007	Phase 4
NCT00909571	Astellas Pharma Inc\|Astellas Pharma Korea, Inc.	Liver Transplantation	April 2009	Phase 3
NCT01608412	Hospital de Clinicas de Porto Alegre	Kidney Transplant Recipients	February 2012	Phase 4
NCT01349101	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematological Malignancies	February 10, 2011	Phase 2
NCT01341301	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Hematologic Malignancy	May 2010	Phase 2
NCT01977781	Massachusetts Eye and Ear Infirmary	Ocular GVHD	December 2013	Phase 1
NCT00204191	Uniwersytet Mikolaja Kopernika w Toruniu\|Astellas Pharma Inc	Kidney Transplantation	May 2003	Phase 4
NCT05457556	Children´s Oncology Group	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Myelodysplastic Syndrome	November 23, 2022	Phase 3
NCT01135329	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Lymphoma\|Leukemia\|Myelodysplastic Syndrome	August 2010	Phase 2
NCT03841097	Roy D. Bloom, MD\|Veloxis Pharmaceuticals\|University of Pennsylvania	Kidney Transplant; Complications	November 11, 2019	Phase 4
NCT00569101	Seoul National University Hospital	Lupus Nephritis	September 2007	Phase 2
NCT00189761	Astellas Pharma Inc	Bone Marrow Transplantation\|Graft Versus Host Disease\|Graft-Vs-Host Disease\|Graft-Versus-Host Disease		Phase 2
NCT01580865	Ramathibodi Hospital\|King Chulalongkorn Memorial Hospital\|Maharaj Nakorn Chiang Mai Hospital\|Rajavithi Hospital\|Srinagarind Hospital, Khon Kaen University\|Siriraj Hospital\|Songklanagarind Hospital	Lupus Nephritis	May 2012	Not Applicable
NCT01190670	Astellas Pharma Inc	Healthy\|Pharmacokinetics of ASP015K and Tacrolimus	July 2010	Phase 1
NCT03465969	Astellas Pharma Europe Ltd.\|Astellas Pharma Inc	Kidney Transplantation\|Liver Transplantation	March 20, 2018	Phase 4
NCT03042637	Southeast Renal Research Institute	Nephrotic Syndrome	January 2012
NCT04521946	M.D. Anderson Cancer Center	Anaplastic Ependymoma\|Atypical Teratoid+Rhabdoid Tumor\|Central Nervous System Germ Cell Tumor\|Choroid Plexus Carcinoma\|Intracranial Myeloid Sarcoma\|Malignant Brain Neoplasm\|Malignant Glioma\|Medulloblastoma\|Primitive Neuroectodermal Tumor\|Recurrent Anaplastic Ependymoma\|Recurrent Atypical Teratoid+Rhabdoid Tumor\|Recurrent Malignant Brain Neoplasm\|Recurrent Malignant Glioma\|Recurrent Medulloblastoma\|Recurrent Primitive Neuroectodermal Tumor	January 14, 2021	Phase 1
NCT00260208	Novartis Pharmaceuticals\|Novartis	Liver Transplant\|Hepatitis C	January 2006	Phase 4
NCT01861106	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	GATA2\|Immunodeficiency\|MDS	July 24, 2013	Phase 2
NCT00309101	Astellas Pharma Inc	Myasthenia Gravis	February 2006	Phase 3
NCT00105235	National Institute of Allergy and Infectious Diseases (NIAID)\|Immune Tolerance Network (ITN)	Liver Disease\|Liver Transplantation	June 2005	Phase 2
NCT04080076	NephroNet, Inc.\|Mallinckrodt	Renal Disease	January 12, 2019	Phase 4
NCT02794610	The Eye Center and The Eye Foundation for Research in Ophthalmology	Ocular Penetration of Topical Tacrolimus	May 2016	Not Applicable
NCT00362531	Peking University	Idiopathic Membranous Nephropathy\|Nephrotic Syndrome	November 2004	Phase 2\|Phase 3
NCT00125307	Chinese University of Hong Kong	Lupus Nephritis\|Lupus Erythematosus, Systemic	January 2004	Phase 4
NCT00058825	Baylor College of Medicine\|The Methodist Hospital Research Institute	Hematologic Malignancies	August 2000	Phase 1\|Phase 2
NCT01390402	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Chronic Myelogenous Leukemia	January 2012	Phase 2
NCT00358657	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Immunodeficiency Syndrome\|Severe Aplastic Anemia\|Genetic Disorder	May 24, 2006	Phase 2
NCT04669210	St. Petersburg State Pavlov Medical University	Graft-versus-host-disease\|Stem Cell Transplant Complications\|Acute Myeloid Leukemia\|Acute Lymphoid Leukemia	November 3, 2020	Phase 2
NCT01224418	Astellas Pharma Inc\|Astellas Pharma Korea, Inc.	Rheumatoid Arthritis	May 2008	Phase 4
NCT00445744	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Myelodysplastic Syndrome With Isolated Del(5q)\|Polycythemia Vera\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Secondary Myelofibrosis\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies	December 2006	Not Applicable
NCT04965597	Fred Hutchinson Cancer Center\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)\|National Marrow Donor Program\|National Heart, Lung, and Blood Institute (NHLBI)	Bone Marrow Failure Syndrome\|Congenital Amegakaryocytic Thrombocytopenia\|Congenital Pure Red Cell Aplasia\|Hereditary Sideroblastic Anemia\|Myeloid Neoplasms With Germline GATA2 Mutation\|Paroxysmal Nocturnal Hemoglobinuria\|Shwachman-Diamond Syndrome	April 19, 2022	Phase 2
NCT01878786	Matthew Cooper\|Georgetown University	Delayed Graft Function	June 2013	Phase 2\|Phase 3
NCT02963103	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Kidney Transplantation	May 2010	Phase 4
NCT02563782	Astellas Institute for Regenerative Medicine\|Astellas Pharma Inc	Age-Related Macular Degeneration	August 24, 2015	Phase 2
NCT00002831	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia	August 1, 1995	Phase 1\|Phase 2
NCT00545493	University Hospital, Bonn\|Octapharma\|Astellas Pharma GmbH	Rasmussen Encephalitis	November 2002	Phase 2\|Phase 3
NCT01707004	University of Wisconsin, Madison\|National Cancer Institute (NCI)	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia	May 16, 2013	Phase 2
NCT00296023	University of California, San Francisco\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	January 1999	Not Applicable
NCT00423514	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	November 20, 2006	Phase 1\|Phase 2
NCT01338987	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Myelodysplastic Syndrome\|Acute Lymphocytic Leukemia\|Acute Myelogenous Leukemia\|Chronic Myelogenous Leukemia\|Chronic Myelomonocytic Leukemia	April 19, 2011	Phase 2
NCT02820259	Rennes University Hospital	Biliary Concentration of Tacrolimus	May 1, 2016
NCT00028600	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Multiple Myeloma\|Plasma Cell Neoplasm	November 2001	Phase 2
NCT04056962	West China Hospital	Tacrolimus, Kaposiform Hemangioendothelioma, Tufted Angioma	September 1, 2019	Phase 4
NCT01745159	Astellas Pharma China, Inc.\|Astellas Pharma Inc	Moderate+Severe Atopic Dermatitis	September 2012	Phase 4
NCT00255710	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	July 2002	Phase 1
NCT00789776	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|The Wayne D. Kuni and Joan E. Kuni Foundation	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Aggressive Non-Hodgkin Lymphoma\|Diffuse Large B-Cell Lymphoma\|Previously Treated Myelodysplastic Syndrome\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Indolent Adult Non-Hodgkin Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hodgkin Lymphoma\|Refractory Plasma Cell Myeloma\|Refractory Small Lymphocytic Lymphoma\|Waldenstrom Macroglobulinemia	October 13, 2008	Phase 1\|Phase 2
NCT01895049	Helio Tedesco Silva Junior\|Novartis\|Sanofi\|Hospital do Rim e Hipertensão	Kidney Transplantation\|Cytomegalovirus	August 2013	Phase 4
NCT03978494	Sandoz	Kidney Transplant	September 2, 2019	Phase 1
NCT00117689	Genzyme, a Sanofi Company\|Sanofi	Liver Dysfunction\|Rejection, Transplant\|Transplantation, Liver	April 2005	Phase 2
NCT00860496	Pfizer	Healthy Volunteers	June 2009	Phase 1
NCT02446964	City of Hope Medical Center\|National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Complete Remission\|Acute Myeloid Leukemia in Remission\|Previously Treated Myelodysplastic Syndrome\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Childhood Acute Lymphoblastic Leukemia in Complete Remission	June 25, 2015	Phase 1
NCT00371319	Tuen Mun Hospital	Lupus Nephritis	September 2005	Phase 4
NCT01131988	Dr. Reddy´s Laboratories Limited	Healthy	January 2008	Phase 1
NCT01789255	National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|B-cell Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Intraocular Lymphoma\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Primary Central Nervous System Hodgkin Lymphoma\|Primary Central Nervous System Non-Hodgkin Lymphoma\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ringed Sideroblasts\|Refractory Chronic Lymphocytic Leukemia\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Hairy Cell Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Central Nervous System Hodgkin Lymphoma\|Secondary Central Nervous System Non-Hodgkin Lymphoma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult Hodgkin Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	June 2013	Phase 2
NCT01551212	Novartis Pharmaceuticals\|Novartis	Liver Transplantation	May 24, 2012	Phase 4
NCT02936505	Vastra Gotaland Region\|Oslo University Hospital\|Helsinki University Central Hospital\|Skane University Hospital\|Copenhagen University Hospital, Denmark	Lung Transplantation\|Allografts	October 2016	Not Applicable
NCT00455013	Bristol-Myers Squibb	Disorder Related to Renal Transplantation	July 2007	Phase 2
NCT03247088	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent Acute Myeloid Leukemia\|Refractory Acute Myeloid Leukemia	July 30, 2017	Phase 1\|Phase 2
NCT01998789	Tomoaki Kato\|Columbia University	Orthotopic Liver Transplant	October 2013	Phase 2
NCT02178683	Colorado Blood Cancer Institute	Graft Versus Host Disease	November 2010	Phase 3
NCT00089011	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Burkitt Lymphoma\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Polycythemia Vera\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Prolymphocytic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Childhood Anaplastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Lymphoblastic Lymphoma\|Stage I Childhood Small Noncleaved Cell Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Multiple Myeloma\|Stage I Small Lymphocytic Lymphoma\|Stage IA Mycosis Fungoides+Sezary Syndrome\|Stage IB Mycosis Fungoides+Sezary Syndrome\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Childhood Anaplastic Large Cell Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Childhood Lymphoblastic Lymphoma\|Stage II Childhood Small Noncleaved Cell Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Multiple Myeloma\|Stage IIA Mycosis Fungoides+Sezary Syndrome\|Stage IIB Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Childhood Anaplastic Large Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Lymphoblastic Lymphoma\|Stage III Childhood Small Noncleaved Cell Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Stage III Small Lymphocytic Lymphoma\|Stage IIIA Mycosis Fungoides+Sezary Syndrome\|Stage IIIB Mycosis Fungoides+Sezary Syndrome\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma\|Stage IVA Mycosis Fungoides+Sezary Syndrome\|Stage IVB Mycosis Fungoides+Sezary Syndrome\|Testicular Lymphoma\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies\|Waldenström Macroglobulinemia	April 2004	Phase 2
NCT02220985	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Undifferentiated Leukemia\|Allogeneic Hematopoietic Stem Cell Transplant Recipient\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Donor\|Lymphoblastic Lymphoma\|Myelodysplastic Syndrome With Excess Blasts\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission	February 3, 2015	Phase 2
NCT00166842	National Taiwan University Hospital	Transplantation\|Kidney Transplantation\|Immunosuppression	September 2002	Phase 4
NCT00028171	National Center for Research Resources (NCRR)	Kidney Transplantation		Not Applicable
NCT03225417	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla	Hematopoietic Stem Cell Transplantation\|Multiple Myeloma	May 16, 2017	Phase 1\|Phase 2
NCT03147157	The First Hospital of Jilin University	Liver Transplantation\|Graft Versus Host Disease\|Graft Rejection\|Drug-Related Side Effects and Adverse Reactions	May 2017	Not Applicable
NCT02736227	Northwestern University\|Novartis Pharmaceuticals	Liver Transplantation	March 2016	Not Applicable
NCT02143479	Astellas Pharma S.A.S.\|Astellas Pharma Inc	Liver Transplantation	June 18, 2014
NCT02373202	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	February 2015	Phase 3
NCT00309088	Astellas Pharma Inc	Myasthenia Gravis	April 2006	Phase 3
NCT01384513	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Thomas Jefferson University	Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Aplastic Anemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|Chronic Eosinophilic Leukemia\|Chronic Myelomonocytic Leukemia\|Chronic Neutrophilic Leukemia\|Essential Thrombocythemia\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Juvenile Myelomonocytic Leukemia\|Mastocytosis\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Polycythemia Vera\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Anemia\|Refractory Anemia With Ringed Sideroblasts\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Secondary Myelodysplastic Syndromes\|Splenic Marginal Zone Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Waldenström Macroglobulinemia	August 4, 2011	Phase 2

Appearance

Solid

Source

fungus Streptomyces tsukubaensis.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 150 mg/mL ( 186.56 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2438 mL	6.2188 mL	12.4375 mL
5 mM	0.2488 mL	1.2438 mL	2.4875 mL
10 mM	0.1244 mL	0.6219 mL	1.2438 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 5% DMSO >> 40% PEG300 >> 5% Tween-80 >> 50% saline

Solubility: 2.75 mg/mL (3.42 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (3.11 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (3.11 mM); Suspended solution; Need ultrasonic
4.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (3.11 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Thomson AW, et al. Mode of action of Tacrolimus (FK506): molecular and cellular mechanisms. Ther Drug Monit. 1995 Dec;17(6):584-91.
[2] Vogel KR, et al. mTOR inhibitors rescue premature lethality and attenuate dysregulation of GABAergic/glutamatergic transcription in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism. J Inherit Metab Dis. 2016 Nov;39(6):877-886.
[3] Zhu H, et al. Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF 1α expression in vivo. Mol Med Rep. 2014 Aug;10(2):585-92.
[4] Okada Y, et al. Tacrolimus ameliorates dextran sulfate sodium-induced colitis in mice: implication of interleukin-1β suppression. Biol Pharm Bull. 2011;34(12):1823-7.
[5] Yuwei He, et al. Drug targeting through platelet membrane-coated nanoparticles for the treatment of rheumatoid arthritis. Nano Res. 30 June 2018.

Synonyms

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-

(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

FR 900506

FK 506

Tsukubaenolide

L 679934

Fujimycin

(-)-FK 506

Tacrolimus

Prograf

Protopic

Advagraf

TacroBell

FK506

Prograph

Envarsus XR

Astagraf XL

Hecoria

Tacropic

Protopy

Modigraf

Envarsus

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