[CAS NO. 1050506-87-0]  GPR120modulator2

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PRODUCTS SPECIFICATIONS [1050506-87-0]

Catalog
HY-50172
Brand
MCE
CAS
1050506-87-0

DESCRIPTION [1050506-87-0]

Overview

MDL-
Molecular Weight387.88
Molecular FormulaC20H18ClNO3S
SMILESO=C(O)CCC1=CC=C(OCC2=NC(C3=CC=CC=C3Cl)=CS2)C=C1C

For research use only. We do not sell to patients.

Summary

GPR120 modulator 2 is a G protein coupled receptor 120 (GPR120) modulator extracted from patent US8394841B2, compound example F13. GPR120 modulator 2 can be used for the research of diseases associated with abnormal or deregulated GPR120, such as diabetes [1] .


IC50 & Target

GPR120 [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL ( 257.81 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5781 mL 12.8906 mL 25.7812 mL
5 mM 0.5156 mL 2.5781 mL 5.1562 mL
10 mM 0.2578 mL 1.2891 mL 2.5781 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 3 mg/mL (7.73 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 3 mg/mL (7.73 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Benzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-
4-[[4-(2-Chlorophenyl)-2-thiazolyl]methoxy]-2-methylbenzenepropanoic acid