[CAS NO. 1075237-97-6]  β-Lactamase-IN-1

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PRODUCTS SPECIFICATIONS [1075237-97-6]

Catelog
HY-19773
Brand
MCE
CAS
1075237-97-6

DESCRIPTION [1075237-97-6]

Overview

MDL-
Molecular Weight251.24
Molecular FormulaC11H13N3O4
SMILESO=C1C=NC2=C(N=C(OC)C=C2)N1C(CO)CO

For research use only. We do not sell to patients.

Summary

β-Lactamase-IN-1 is an inhibitor of β-Lactamase extracted from patent WO2016027249A1, page 77. β-Lactamase-IN-1 can be used to prepare of tricyclic nitrogen containing compound. β-Lactamase-IN-1 can be used for the research of neisseria gonorrhea infection [1] .


In Vitro

β-Lactamase-IN-1 can be used to prepare of tricyclic nitrogen containing compound which is an antibacterial agent [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 398.03 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9803 mL 19.9013 mL 39.8026 mL
5 mM 0.7961 mL 3.9803 mL 7.9605 mL
10 mM 0.3980 mL 1.9901 mL 3.9803 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (9.95 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (9.95 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.


Synonyms

Pyrido[2,3-b]pyrazin-3(4H)-one, 4-[2-hydroxy-1-(hydroxymethyl)ethyl]-6-methoxy-
4-[2-Hydroxy-1-(hydroxymethyl)ethyl]-6-methoxypyrido[2,3-b]pyrazin-3(4H)-one
4-[2-Hydroxy-1-(hydroxymethyl)ethyl]-6-(methyloxy)pyrido[2,3-b]pyrazin-3(4H)-one