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[CAS NO. 113665-84-2] Clopidogrel

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Catalog:	HY-15283
Brand:	MCE
CAS:	113665-84-2

Overview

MDL	MFCD05662337
Molecular Weight	321.82
Molecular Formula	C16H16ClNO2S
SMILES	ClC1=C(C=CC=C1)[C@H](N2CCC3=C(C2)C=CS3)C(OC)=O

For research use only. We do not sell to patients.

10 Publications Citing Use of MCE

[1]Int J Biol Sci. 2019 Jan 1;15(1):239-252.
[2]Int J Mol Sci. 2022, 23(16), 9118.
[3]Front Pharmacol. 2022 Jan 10;12:792263.
[4]J Appl Physiol (1985). 2021 Sep 30.
[5]Am J Transl Res. 2020 May 15;12(5):1741-1753.
[6]Drug Des Devel Ther. 2020 Dec 21;14:5599-5610.
[7]ACS Omega. 2020 Aug 4;5(32):19995-20003.
[8]J Food Biochem. 2020 Sep;44(9):e13352.
[9]Open Chem. 2020 Jun.
[10]J Pharm Health Care Sci. 2021 May 4;7(1):18.

Summary

Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.

IC50 & Target

P2Y12 receptor ^[1] .

In Vivo

Clopidogrel, administered during the last three months, significantly decreases blood glucose, collagen and fibronectin expression compared to vehicle-treated diabetic mice. Clopidogrel markedly ameliorates hyperglycemia-induced renal fibrosis ^[1] . The combination therapy of clopidogrel and aspirin (dual-antiplatelet therapy) has been shown to be significantly beneficial compared to aspirin monotherapy and has also shown to decrease sub-acute stent thrombosis as well as recurrent ischemic events following ACS ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT02052635	AstraZeneca	Non-ST Elevation Acute Coronary Syndrome	September 2014	Phase 4
NCT00661206	Deutsches Herzzentrum Muenchen	Coronary Artery Disease	September 2008	Phase 4
NCT04069234	Region Skane\|IHF GmbH - Institut für Herzinfarktforschung\|Hippocrates Research\|IRW consulting AB\|AstraZeneca	Diabetes Mellitus\|Microvascular Coronary Artery Disease	September 15, 2019	Phase 3
NCT02612480	Radboud University Medical Center	Endotoxemia	October 2015	Not Applicable
NCT00421252	Beth Israel Deaconess Medical Center	Coronary Artery Disease\|Myocardial Ischemia\|Bleeding	January 2007	Phase 4
NCT00799396	University of Maryland, Baltimore\|National Institute of General Medical Sciences (NIGMS)\|National Heart, Lung, and Blood Institute (NHLBI)	Platelet Aggregation Inhibitors\|Coronary Heart Disease	July 2006	Phase 4
NCT01586975	Northwestern University	Stroke\|Myocardial Infarctions	July 2007	Phase 2\|Phase 3
NCT02071966	Catholic University of the Sacred Heart	Non ST Segment Elevation Acute Coronary Syndrome	November 2012	Phase 4
NCT04078737	Beijing Tiantan Hospital\|Ministry of Science and Technology of the People´s Republic of China	Stroke\|Transient Ischemic Attack	September 23, 2019	Phase 3
NCT00296803	Sanofi\|Bristol-Myers Squibb	Metabolic Syndrome x	November 2005	Phase 4
NCT04695106	Medical University of Gdansk\|Medical University of Warsaw\|Nicolaus Copernicus University\|Institute of Cardiology, Warsaw, Poland\|Military Institute of Medicine, Poland\|Bielanski Hospital\|Medical University of Silesia\|Poznan University of Medical Sciences\|University of Opole, Poland\|Medical University of ?ód?\|Voivodeship Hospital, Kielce, Poland\|Voivode Specialist Hospital in Olsztyn, Poland\|Medical University of Lublin\|Pomeranian Medical University Szczecin\|Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland	Atrial Fibrillation\|Antithrombotic Therapy\|Acute Coronary Syndrome\|Percutaneous Coronary Interventions	October 25, 2021	Phase 4
NCT02265289	Boehringer Ingelheim	Healthy	January 1999	Phase 1
NCT02415803	First Affiliated Hospital of Harbin Medical University	Non ST Segment Elevation Acute Coronary Syndrome	December 2014	Phase 3
NCT03463317	Charite University, Berlin, Germany\|Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)\|Atrial Fibrillation Network\|Stiftung Institut fuer Herzinfarktforschung	Atrial Fibrillation	February 28, 2018	Phase 4
NCT05320926	Yonsei University	Ischemic Heart Disease	March 11, 2022	Not Applicable
NCT00404781	Shenyang Northern Hospital	Ischemic Heart Disease\|Acute Coronary Syndromes	June 2006	Phase 4
NCT00623623	Boehringer Ingelheim	Myocardial Infarction	March 1, 2008	Phase 3
NCT01657071	Yuhan Corporation	Acute Coronary Syndrome	March 2012	Phase 1
NCT01325935	Associations for Establishment of Evidence in Interventions\|Medtronic	Coronary Artery Disease	April 2011	Phase 4
NCT03198741	Shenyang Northern Hospital\|Changhai Hospital\|ANKON medical technologies (Shanghai)Co.,LTD	Gastrointestinal Injury\|Ischemic Heart Disease	July 13, 2017	Phase 4
NCT01765400	University of Nebraska\|Daiichi Sankyo, Inc.\|Eli Lilly and Company	Systolic Heart Failure	February 2013	Phase 4
NCT00620646	Samsung Medical Center	Clopidogrel Non-Responsiveness	February 2008	Not Applicable
NCT04060914	Beijing Anzhen Hospital	Antiplatelet Therapy\|Coronary Artery Disease\|Percutaneous Coronary Intervention	August 30, 2019	Phase 4
NCT02244710	Fundación Investigación Sanitaria en León\|AstraZeneca	Acute Coronary Syndrome (ACS)	March 2015	Not Applicable
NCT00222573	University of Oxford\|Sanofi\|AstraZeneca	Acute Myocardial Infarction	July 1999	Phase 4
NCT02618733	Dong-A University\|AstraZeneca\|Biotronik SE & Co. KG	Acute Coronary Syndrome	December 2014	Not Applicable
NCT03207451	Inova Health Care Services\|Merck Sharp & Dohme LLC	Coronary Artery Disease\|Peripheral Vascular Disease\|Myocardial Infarction	January 1, 2016	Phase 4
NCT00140465	Deutsches Herzzentrum Muenchen\|Technical University of Munich	Coronary Disease	October 2004	Phase 4
NCT01621763	Dr. Reddy´s Laboratories Limited	Healthy	September 2008	Phase 1
NCT01233167	Sir Run Run Shaw Hospital	Coronary Artery Disease	August 2011	Not Applicable
NCT04688723	Zuyderland Medisch Centrum\|Boehringer Ingelheim	Coronary Artery Disease\|Myocardial Ischemia\|Myocardial Infarction\|Atrial Fibrillation	December 23, 2020	Phase 4
NCT02677545	University Hospital, Basel, Switzerland	Carotid Artery Stenosis	December 2016	Phase 2
NCT01584791	Seoul National University Hospital\|Hanmi Pharmaceutical co., ltd.	Coronary Artery Disease	October 2010	Phase 4
NCT04981041	Ludwig-Maximilians - University of Munich	Acute Coronary Syndrome\|Atrial Fibrillation	December 16, 2021	Phase 4
NCT02133989	Samsung Medical Center\|Yuyu Pharma, Inc.	Carotid Stenosis	June 2014	Phase 3
NCT05209412	Xijing Hospital	De Novo Stenosis\|Coronary Artery Disease\|Percutaneous Coronary Intervention	February 1, 2022	Not Applicable
NCT05504330	Anhui Medical University	Asymptomatic Intracranial Stenosis\|Cognitive Impairment\|Cerebrovascular Event	August 15, 2022
NCT01267734	Seoul National University Hospital\|Boston Scientific Corporation	Coronary Heart Disease	June 2010	Phase 4
NCT02792712	Taipei Veterans General Hospital, Taiwan	Acute Coronary Syndrome	January 2016	Phase 4
NCT04418479	Joo-Yong Hahn\|Samsung Medical Center	Coronary Artery Disease	August 10, 2020	Phase 4
NCT02294643	Seoul National University Bundang Hospital\|Yuhan Corporation	Coronary Artery Disease\|Diabetes Mellitus\|Renal Insufficiency, Chronic	April 2009	Phase 3
NCT01826175	Massachusetts General Hospital\|AstraZeneca	Acute Coronary Syndrome\|Coronary Artery Disease	May 2013	Phase 4
NCT02560688	Daiichi Sankyo, Inc.	Drug Interaction	December 2015	Phase 1
NCT02391883	Hvidovre University Hospital	Hip Fracture	January 2011
NCT00751491	University of Roma La Sapienza	Stable Angina\|Percutaneous Coronary Intervention	September 2008	Phase 3
NCT01338909	University of Patras	Myocardial Infarction	April 2011	Phase 3
NCT04630288	Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud\|Andalusian Network for Design and Translation of Advanced Therapies	Acute Coronary Syndromes	July 2, 2019
NCT00914368	Uppsala University	Coronary Artery Disease\|Myocardial Infarction\|Stent Thrombosis\|Heart Diseases\|Acute Coronary Syndrome	January 2009	Phase 2
NCT00774475	University of Florence\|Tuscany Region	Unstable Angina\|NSTEMI	November 2008	Phase 3
NCT00007683	US Department of Veterans Affairs\|Sanofi-Synthelabo\|Bristol-Myers Squibb\|VA Office of Research and Development	Heart Failure	October 1998	Phase 3
NCT00716924	Sanofi\|Bristol-Myers Squibb	Thrombosis	May 2004	Phase 3
NCT01032668	Bursa Postgraduate Hospital	Coronary Artery Disease	September 2008	Phase 3
NCT02376283	The Royal Wolverhampton Hospitals NHS Trust	Heart Attack	March 9, 2015	Phase 4
NCT00097591	Eli Lilly and Company\|Daiichi Sankyo, Inc.	Coronary Arteriosclerosis\|Acute Coronary Syndromes	November 2004	Phase 3
NCT02606552	Yonsei University	Atrial Fibrillation\|Coronary Artery Disease	July 20, 2016	Phase 4
NCT00404053	Shenyang Northern Hospital	Acute Coronary Syndrome	December 2004	Phase 4
NCT00891670	Gyeongsang National University Hospital	Coronary Artery Stenosis\|Maximal Platelet Aggregation\|Late Platelet Aggregation\|High Post-Treatment Platelet Reactivity	May 2009	Phase 3
NCT04484259	University of Florida\|AstraZeneca	Diabetes Mellitus, Type 2\|Coronary Artery Disease	March 31, 2021	Phase 4
NCT01805596	Lawson Health Research Institute	Coronary Artery Disease\|Endothelial Function	April 2013	Phase 3
NCT03245489	Medical University of South Carolina	Head and Neck Cancer	October 20, 2017	Phase 1
NCT02617290	Assistance Publique - Hôpitaux de Paris\|Action Research Group\|AstraZeneca	Coronary Artery Disease\|Myocardial Ischemia\|Myocardial Infarction\|Stent Thrombosis\|Cardiovascular Diseases	January 9, 2017	Phase 3
NCT00115375	Sanofi\|Bristol-Myers Squibb	Congenital Heart Defects\|Blood Platelet Disorders	January 2004	Phase 2
NCT03161678	University of Maryland, Baltimore	Myocardial Infarction\|Thrombosis\|Platelet Dysfunction	August 22, 2017	Phase 4
NCT01456546	University of Southern Denmark	CYP2C19 Genotypes	October 2011	Phase 1
NCT03103685	Chiang Mai University	Dental Diseases\|Antiplatelet Agents\|Antiplatelet Drugs	May 1, 2017	Phase 4
NCT03381742	First Affiliated Hospital of Harbin Medical University\|Beijing Anzhen Hospital\|The First Affiliated Hospital of Dalian Medical University\|The Central Hospital of Jia Mu Si City\|The First Affiliated Hospital of Kunming Medical College\|RenJi Hospital\|Tianjin Medical University General Hospital\|Weifang People´s Hospital\|Wuhan Union Hospital, China\|Shengjing Hospital\|Shaanxi Provincial People´s Hospital	Coronary Artery Disease	December 13, 2017	Phase 2\|Phase 3
NCT00153062	Boehringer Ingelheim\|GlaxoSmithKline\|Bayer	Stroke	August 2003	Phase 4
NCT01523392	AstraZeneca	Stable Coronary Artery Disease	March 2012	Phase 4
NCT02429271	Hellenic Cardiovascular Research Society	Myocardial Infarction\|ST Segment Elevation Myocardial Infarction (STEMI)	August 2015	Phase 3
NCT02711410	National Cerebral and Cardiovascular Center	Platelet Aggregation Inhibitors	October 2009
NCT01543932	University of Roma La Sapienza	Coronary Artery Disease	July 2012	Phase 3
NCT03679091	First Affiliated Hospital of Harbin Medical University	Platelet Reactivity	August 29, 2018	Phase 4
NCT00642174	Eli Lilly and Company\|Daiichi Sankyo, Inc.	Diabetes Mellitus\|Coronary Artery Disease	April 2008	Phase 2
NCT02975076	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	Stroke, Acute\|Ischemic Attack, Transient	December 2016	Not Applicable
NCT02499666	Henry Ford Health System	Coronary Artery Disease\|Angina Pectoris	June 29, 2015
NCT02209350	Meshalkin Research Institute of Pathology of Circulation	Aorta-iliac Segment Lesion (C,D Type by TASC II)	August 2, 2014	Phase 1
NCT00152724	University Hospital, Angers	Healthy Volunteers	January 1996
NCT01642238	Juan J Badimon\|AstraZeneca\|Icahn School of Medicine at Mount Sinai	Acute Coronary Syndrome	July 2012	Phase 4
NCT02578537	Shenyang Northern Hospital	Non ST Segment Elevation Acute Coronary Syndrome\|Chronic Kidney Disease	October 2015	Phase 4
NCT01037491	Taipei Veterans General Hospital, Taiwan	Gastric Ulcer\|Duodenal Ulcer	October 2009	Not Applicable
NCT01924325	Xijing Hospital	Ischemic Stroke\|TIA	January 2014	Phase 2\|Phase 3
NCT01118325	AstraZeneca	Stable Coronary Artery Disease	April 2010	Phase 2
NCT01959191	Yonsei University	Coronary Artery Disease	January 2008
NCT02217501	University of Texas Southwestern Medical Center	Peripheral Arterial Disease	November 2015	Phase 3
NCT02626169	Baylor College of Medicine	Atherosclerosis	December 2015	Phase 4
NCT02224274	University Medical Centre Ljubljana	Cardiac Arrest\|Postresuscitation Syndrome\|Myocardial Infarction (ST-Elevation Myocardial Infarction and Non-ST-Elevation Myocardial Infarction)	August 2014	Phase 4
NCT00589862	Creighton University	Coronary Artery Disease	October 2007	Phase 4
NCT00776477	China National Center for Cardiovascular Diseases	Atherosclerosis	December 2007	Phase 3
NCT00687076	Baylor College of Medicine\|National Heart, Lung, and Blood Institute (NHLBI)	Peripheral Arterial Disease	April 2004	Phase 4
NCT02594410	Lee´s Pharmaceutical Limited	Hypertension	September 2011	Phase 4
NCT04850001	Anhui Medical University	Magnetic Resonance Imaging\|Asymptomatic Intracranial Stenosis\|Medical Treatment	September 10, 2020
NCT01103440	Icahn School of Medicine at Mount Sinai	Stable Angina	April 2007	Phase 2
NCT00833703	Sanofi\|Bristol-Myers Squibb	Heart Defects, Congenital	January 2009	Phase 3
NCT02048085	Medical Center of South Arkansas	Acute ST Segment Elevation Myocardial Infarction\|Acute Coronary Syndrome	January 2, 2014	Phase 4
NCT00650169	Mylan Pharmaceuticals Inc\|MylanPharma	Healthy	December 2004	Phase 1
NCT00857155	LifeBridge Health	Coronary Artery Disease	January 2009	Not Applicable
NCT01108588	Merck Sharp & Dohme LLC	Healthy Volunteers	June 2010	Phase 1
NCT02037412	Yonsei University	Acute Coronary Syndrome\|Acute Myocardial Infarction\|Unstable Angina (Intermediate Coronary Syndrome)	January 2014	Phase 4
NCT04624854	Harbin Medical University\|Chinese Society of Cardiology\|Lepu Medical Technology (Beijing) Co., Ltd.	Coronary Artery Disease\|Myocardial Ischemia\|Acute Coronary Syndrome\|Heart Diseases\|Syndrome Heart Disease\|Cardiovascular Diseases\|Arteriosclerosis\|Arterial Occlusive Diseases\|Coronary Disease\|Vascular Diseases	October 27, 2020	Phase 4
NCT01304472	University of Patras	Coronary Artery Disease (CAD)	February 2011	Phase 3
NCT01449617	Azienda Ospedaliera di Perugia\|University Of Perugia	Carotid Artery Disease	August 2010
NCT00827346	Ottawa Heart Institute Research Corporation	Platelet Reactivity	January 2009	Phase 2\|Phase 3
NCT02960126	Chuncheon Sacred Heart Hospital	Atrial Fibrillation	November 2016	Phase 3
NCT00751231	Portola Pharmaceuticals	Percutaneous Coronary Intervention	December 2008	Phase 2
NCT01823185	Imam Abdulrahman Bin Faisal University\|King Fahad Armed Forces Hospital\|Dammam Central Hospital	Coronary Artery Disease\|Myocardial Infarction\|Heart Disease\|Vascular Disease\|Angina Pectoris\|Cardiovascular Disease\|Ischemia\|Infarction\|Embolism\|Thrombosis\|Chest Pain	March 2013	Phase 4
NCT02506140	Beijing Tiantan Hospital\|Beijing Municipal Science & Technology Commission	Stroke\|Ischemic Attack, Transient	August 2015	Phase 2\|Phase 3
NCT01641510	Dong-A University	Acute Coronary Syndromes	October 2013	Phase 3
NCT00224809	Baylor Research Institute\|National Heart, Lung, and Blood Institute (NHLBI)	Cardiovascular Diseases\|Heart Diseases\|Coronary Disease	September 2002	Not Applicable
NCT01757262	AstraZeneca	Coronary Heart Disease	January 2013	Phase 3
NCT00406991	Schepens Eye Research Institute\|Massachusetts Eye and Ear Infirmary	Diabetes\|Diabetic Retinopathy	June 2003	Phase 2
NCT01452152	University of Maryland, Baltimore\|National Heart, Lung, and Blood Institute (NHLBI)	Cardiovascular Diseases\|Acute Coronary Syndrome	February 2012	Phase 4
NCT04847752	Tongji Hospital	Ischemic Stroke\|Large-Artery Atherosclerosis (Embolus+Thrombosis)	March 1, 2021
NCT01778842	Gennaro Sardella\|University of Roma La Sapienza	Coronary Artery Disease	March 2013	Phase 3
NCT05353140	Xijing Hospital	Atrial Fibrillation\|Percutaneous Coronary Intervention	September 1, 2022	Not Applicable
NCT01469416	University of California, San Francisco	Healthy	March 2012	Phase 1
NCT00827411	Assistance Publique - Hôpitaux de Paris\|Allies in Cardiovascular Trials Initiatives and Organized\|Institut National de la Santé Et de la Recherche Médicale, France\|Sanofi\|Bristol-Myers Squibb\|Medtronic\|Cordis Corporation\|Fondation de France\|Diagnostica Stago\|Boston Scientific Corporation	Coronary Artery Disease\|Acute Coronary Syndrome	January 2009	Phase 4
NCT04229264	Science Valley Research Institute\|Wyeth is now a wholly owned subsidiary of Pfizer	Critical Limb Ischemia	January 9, 2020	Phase 3
NCT03224923	Ottawa Heart Institute Research Corporation	Stable Coronary Syndrome\|Percutaneous Coronary Intervention\|Antiplatelet Therapy\|Ticagrelor	August 18, 2017	Phase 4
NCT01887704	Capital Medical University\|Beijing Anzhen Hospital	Coronary Artery Disease	January 2010	Not Applicable
NCT01823510	Juan J Badimon\|AstraZeneca\|Icahn School of Medicine at Mount Sinai	Type-2 Diabetes Mellitus\|Coronary Artery Disease	July 2013	Phase 4
NCT02570581	Centre Hospitalier Universitaire de Nice	Healthy	June 2014	Phase 1
NCT03431142	Shenyang Northern Hospital	Prolonged DAPT in ACS Patients With Hisk of Both Ischemic and Hemorrhage	February 12, 2018	Phase 4
NCT02293395	Janssen Research & Development, LLC\|Bayer\|Duke Clinical Research Institute\|Harvard Medical School (HMS and HSDM)	Acute Coronary Syndrome	April 20, 2015	Phase 2
NCT02262650	Boehringer Ingelheim	Healthy	April 2004	Phase 1
NCT01509365	Les Laboratoires des Médicaments Stériles\|University Hospital Fattouma Bourguiba	Cardiovascular Disease\|Overweight	December 2011	Phase 4
NCT02260622	Ottawa Hospital Research Institute\|The Ottawa Hospital	Critical Limb Ischemia	October 2014	Phase 2
NCT00566891	S. Anna Hospital	Coronary Artery Disease	December 2007	Phase 4
NCT00413608	Assistance Publique - Hôpitaux de Paris	Healthy	January 2007	Phase 1
NCT01744288	AstraZeneca	Inhibition on Platelet Aggregation	December 2012	Phase 1
NCT01515345	Kaiser Franz Josef Hospital	Platelet Inhibition\|Coronary Stent Implantation	July 2011	Phase 3
NCT01830543	Janssen Scientific Affairs, LLC\|Bayer	Atrial Fibrillation\|Percutaneous Coronary Intervention	May 10, 2013	Phase 3
NCT01157455	CCRF Consulting Co., Ltd.	Coronary Artery Diseases	May 2010	Phase 4
NCT04023630	Second Affiliated Hospital, School of Medicine, Zhejiang University	Atrial Fibrillation\|Acute Coronary Syndromes	October 1, 2019	Phase 4
NCT03581409	Seoul National University Hospital\|Seoul National University Bundang Hospital	Aneurysm, Cerebral\|Endovascular Procedures	October 24, 2018	Phase 4
NCT03437044	University of Florida\|AstraZeneca	Diabetes Mellitus, Type 2\|Coronary Artery Disease	March 14, 2018	Phase 4
NCT04237922	Brigham and Women´s Hospital	Antiplatelet	September 22, 2019
NCT00368238	Yale University\|American Heart Association	Healthy Subjects	October 2005	Phase 2
NCT04501900	Shanghai Zhongshan Hospital	Cardiovascular Diseases	October 2020	Phase 4
NCT02953405	Daewoong Pharmaceutical Co. LTD.	MCA - Middle Cerebral Artery Dissection	December 2015
NCT02798874	Chinese PLA General Hospital	Cardiovascular Diseases	May 2016	Not Applicable
NCT01135667	Lene Holmvang\|Rigshospitalet, Denmark	Coronary Artery Disease\|Percutaneous Coronary Intervention\|Acute Coronary Syndromes	September 2010	Phase 4
NCT02120092	Medical University of Vienna	Acute Coronary Syndrome	October 2010	Phase 2
NCT03729401	Ottawa Heart Institute Research Corporation	Coronary Artery Disease\|Myocardial Infarction	August 22, 2019	Phase 4
NCT00822536	Assistance Publique - Hôpitaux de Paris\|Fédération Française de Cardiologie	Coronary Artery Disease\|Stent Thrombosis\|Myocardial Ischemia	January 2009	Phase 4
NCT02185534	AstraZeneca	Bioequivalence, AUC, Cmax, Pharmacokinetics	August 2014	Phase 1
NCT01665235	RenJi Hospital	Blood Pressure Variability\|Intracranial Artery Stenosis	August 2012	Not Applicable
NCT00385138	The Medicines Company	Atherosclerosis\|Acute Coronary Syndrome (ACS)	September 2006	Phase 3
NCT02689037	The 476th Hospital of People´s Liberation Army	Intracranial Atherosclerosis	April 2016	Phase 3
NCT05122455	University of Sao Paulo\|Daiichi Sankyo, Inc.	SCAD\|AMI	September 14, 2021	Phase 2\|Phase 3
NCT03188705	University of Maryland, Baltimore	Heart Diseases\|Coronary Disease\|Coronary Artery Disease\|Cardiovascular Diseases\|Myocardial Ischemia\|Artery Occlusion\|Aspirin Sensitivity\|Clopidogrel, Poor Metabolism of\|Platelet Dysfunction\|Platelet Thrombus	October 14, 2019	Phase 4
NCT00638326	University of Pecs	Stable Angina Pectoris\|Ad Hoc Percutaneous Coronary Intervention	March 2008	Phase 3
NCT01129271	Sanofi\|Bristol-Myers Squibb	Healthy	April 2009	Phase 1
NCT03392051	Akcea Therapeutics	Elevated Lipoprotein(a)\|Cardiovascular Diseases	December 28, 2017	Phase 1
NCT01327534	Stiftung Institut fuer Herzinfarktforschung\|Daiichi Sankyo, Inc.	Myocardial Infarction\|STEMI	May 2011	Phase 3
NCT03691688	Shanghai Zhongshan Hospital	Coronary Artery Disease\|Hyperuricemia	December 1, 2018
NCT03787927	Bloodworks\|National Blood Foundation	Bleeding\|Platelet Dysfunction Due to Drugs\|Platelet Dysfunction	December 3, 2018	Phase 1\|Phase 2
NCT05566301	IRCCS Policlinico S. Donato	Clopidogrel, Poor Metabolism of\|Carotid Stenosis	September 2, 2021
NCT01994941	The University of Hong Kong	Acute Coronary Syndrome	August 2013	Phase 4
NCT00444132	Sheba Medical Center	Clopidogrel Non-Responsiveness	March 2005	Phase 3
NCT04734028	Gyeongsang National University Hospital\|Korean Society of Interventional Cardiology	Coronary Artery Disease\|Clopidogrel, Poor Metabolism of\|Platelet Dysfunction\|Stent Thrombosis	July 9, 2003
NCT01294462	AstraZeneca	Acute Coronary Syndrome\|Percutaneous Coronary Intervention	February 2011	Phase 3
NCT04237935	Brigham and Women´s Hospital	Antiplatelet	September 22, 2019
NCT02696330	Ain Shams Maternity Hospital	Female , Infertility	September 2015	Phase 4
NCT04809818	Lumosa Therapeutics Co., Ltd.	Acute Ischemic Stroke	March 21, 2021	Phase 1
NCT00300339	Sanofi	Intermittent Claudication	February 2006	Phase 2
NCT01789814	Tufts Medical Center	Coronary Artery Disease	July 2013	Phase 4
NCT01526122	Dong-A ST Co., Ltd.	Atherosclerosis	September 2011	Phase 1
NCT02096419	University of Zagreb\|Clinical Hospital Centre Zagreb\|Ministry of Science, Education and Sport, Republic of Croatia	Acute Coronary Syndrome	February 2012	Phase 4
NCT05476081	University of L´Aquila	Ischemic Stroke\|TIA	February 3, 2021
NCT01158703	Ahmad Slim\|Bristol-Myers Squibb\|Brooke Army Medical Center	Coronary Graft Patency	July 2010	Phase 4
NCT03289520	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|The Cleveland Clinic\|Boston University\|Duke University\|University of Iowa\|MaineHealth\|University of Texas Southwestern Medical Center\|University of Alabama at Birmingham\|Washington University School of Medicine\|Baystate Medical Center\|Vanderbilt University\|CAMC Health System\|Emory University\|St. Louis University\|Tyler Nephrology Associates\|Vascular Surgery Associates LLC	Kidney Failure\|Hemodialysis Fistula Thrombosis	January 7, 2003	Phase 3
NCT01113372	Cardiovascular Research Center, Brazil\|Medtronic	Coronary Artery Disease	April 2010	Phase 4
NCT02317198	St. Antonius Hospital\|UMC Utrecht\|Leiden University Medical Center\|Meander Medical Center\|Medical Center Alkmaar\|Isala\|Gelre Hospitals\|Gelderse Vallei Hospital\|Medical Centre Leeuwarden\|Rijnstate Hospital	Non-ST-elevation Acute Coronary Syndrome\|Unstable Angina\|Non-ST-elevation Myocardial Infarction	June 2013	Phase 4
NCT01118793	Scripps Health\|National Center for Research Resources (NCRR)	Coronary Artery Disease	December 2008
NCT01496261	Chong Kun Dang Pharmaceutical\|Inje University	Coronary Artery Disease	August 2011	Phase 1
NCT04561739	Xijing Hospital	De Novo Stenosis\|Coronary Artery Disease	February 1, 2021	Not Applicable
NCT00991029	University of California, San Francisco\|Neurological Emergencies Treatment Trials Network (NETT)\|Medical University of South Carolina\|The Emmes Company, LLC	Ischemic Attack, Transient	May 28, 2010	Phase 3
NCT01538446	Assistance Publique - Hôpitaux de Paris\|Eli Lilly and Company\|Daiichi Sankyo, Inc.\|Allies in Cardiovascular Trials Initiatives and Organized\|Accumetrics, Inc.\|Stentys	Acute Coronary Syndrome	March 2012	Phase 4
NCT05493657	Yonsei University	Severe Aortic Stenosis	September 15, 2022	Not Applicable
NCT02777580	KU Leuven\|Boehringer Ingelheim\|Life Sciences Research Partners\|Fund for Clinical Cardiovascular Research at LRD	Myocardial Infarction	August 1, 2017	Phase 4
NCT00940784	Ronald Hoffman\|Myeloproliferative Disorders-Research Consortium\|National Cancer Institute (NCI)\|Icahn School of Medicine at Mount Sinai	Polycythemia Vera	June 2009	Phase 2
NCT02513004	Yongjian Wu\|Chinese Academy of Medical Sciences, Fuwai Hospital	Coronary Disease	June 2015	Phase 4
NCT04671069	Madrigal Pharmaceuticals, Inc.	Healthy	July 26, 2019	Phase 1
NCT01493999	University of Pecs	Acute Coronary Syndrome	September 2011	Phase 4
NCT04822363	Beth Israel Deaconess Medical Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health (NIH)	Platelet Activation Testing Before+After Anti-platelet Therapy\|Healthy	August 20, 2021	Early Phase 1
NCT00189618	Arteriogenesis Competence Network	Peripheral Arterial Disease	May 2005	Phase 4
NCT04770012	Ottawa Heart Institute Research Corporation\|Canadian Institutes of Health Research (CIHR)	Cardiac Allograft Vasculopathy\|Heart Transplant	June 28, 2021	Phase 3
NCT02459288	Ping-Yen Liu\|National Cheng-Kung University Hospital	Acute Coronary Syndrome\|Chronic Kidney Disease\|End-Stage Renal Disease	January 2014	Phase 4
NCT00699998	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.\|Duke Clinical Research Institute	Acute Coronary Syndrome	June 2008	Phase 3
NCT04698031	VA Office of Research and Development	Silent Brain Infarction	March 30, 2022	Phase 4
NCT01732822	AstraZeneca	Peripheral Artery Disease	December 4, 2012	Phase 3
NCT00662467	Hamilton Health Sciences Corporation\|McMaster University	Myocardial Infarction	November 2006	Not Applicable
NCT04407312	Gyeongsang National University Hospital\|Korea Otsuka Pharmaceutical Co., Ltd.	Myocardial Infarction, Acute	January 1, 2016	Phase 4
NCT05193071	General Hospital of Shenyang Military Region	Ischemic Stroke	July 8, 2022	Phase 4
NCT02457130	Spanish Society of Cardiology\|AstraZeneca	Coronary Artery Disease\|Diabetes Mellitus. Type 2	April 2015	Phase 4
NCT03649711	University of Arkansas\|American Society of Nephrology	Chronic Kidney Diseases\|Heart Attack\|Stroke, Ischemic	November 1, 2018	Phase 3
NCT01112137	University of Cologne	Blood Pressure\|Endothelial Function\|Platelet Function	January 2005	Phase 4
NCT00004564	National Center for Research Resources (NCRR)	Hypercholesterolemia\|Thrombosis		Not Applicable
NCT00732290	Centre Hospitalier Universitaire de Saint Etienne	Healthy	February 2009	Phase 1
NCT01779401	Chinese Academy of Medical Sciences, Fuwai Hospital\|Beijing Municipal Health Bureau\|Haemonetics Corporation\|Zhejiang Otsuka Pharmaceutical Co., Ltd.	Coronary Heart Disease	September 2012	Not Applicable
NCT02776540	Ain Shams University	Ischemic Cerebrovascular Accident	June 1, 2016	Phase 4
NCT02230527	The Cleveland Clinic	Peripheral Arterial Disease	October 2014	Phase 2\|Phase 3
NCT01175200	Ascopharm Groupe Novasco\|Groupe Hospitalier Pitie-Salpetriere\|Medco Health Solutions, Inc.	Anti Platelet Effects	September 2010	Not Applicable
NCT01129388	Sanofi\|Bristol-Myers Squibb	Healthy	March 2009	Phase 1
NCT01626534	Assistance Publique Hopitaux De Marseille	Acute Coronary Syndrome	March 2012	Phase 3
NCT04305587	Pfizer	Diabetes Mellitus Type 2	March 16, 2020	Phase 1
NCT01663038	Chong Kun Dang Pharmaceutical\|Inje University	Coronary Artery Disease	December 2010	Phase 1
NCT03357874	Assistance Publique Hopitaux De Marseille	Acute Coronary Syndrome	October 28, 2018	Phase 3
NCT00249873	Sanofi\|Bristol-Myers Squibb	Atrial Fibrillation\|Vascular Risk	June 2003	Phase 3
NCT00642811	AstraZeneca	Stable Coronary Artery Disease	May 2008	Phase 2
NCT05554822	Azienda Ospedaliero Universitaria Maggiore della Carita\|Abbott Medical Devices	Left Atrial Appendage Occlusion\|Antiplatelet Therapy	June 14, 2021	Phase 3
NCT04483583	University of Florida	Coronary Artery Disease	December 10, 2020	Phase 4
NCT00799045	Laval University\|Sanofi\|Bristol-Myers Squibb	Migraine	October 2008	Phase 4
NCT02580149	Michael Wolzt, Prof. MD\|Medical University of Vienna	Ischemia	October 2015	Phase 4
NCT01813435	ECRI bv\|Biosensors International\|AstraZeneca\|The Medicines Company	Coronary Artery Disease (CAD)	July 1, 2013	Phase 3
NCT01955512	University of Southampton	Asthma	May 2013	Phase 2
NCT04174261	Hellenic Society of Interventional Cardiology	Periprocedural Myocardial Infarction	January 29, 2017	Phase 4
NCT02404363	Assistance Publique - Hôpitaux de Paris\|Groupe Francophone Thrombose et Cancer	Locally Advanced Pancreatic Cancer\|Adenocarcinoma, Pancreas\|Metastatic Pancreatic Cancer	January 11, 2016	Phase 3
NCT02428374	Federal University of São Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Myocardial Fibrosis	May 2015	Phase 4
NCT02469740	University Hospital of Limerick	Myocardial Ischemia\|Coronary Artery Disease\|Endothelial Dysfunction	July 2015	Phase 4
NCT02748330	Peking Union Medical College Hospital	Coronary Artery Disease\|Diabetes Mellitus, Type 2	June 2016	Phase 4
NCT02334254	Beijing Anzhen Hospital	Atrial Fibrillation	August 2013	Phase 4
NCT01012544	St. Antonius Hospital\|University of Cologne	Coronary Artery Stent Thrombosis	April 2009	Phase 4
NCT05223335	Mayo Clinic	Bleeding Complications	March 29, 2022	Phase 4
NCT00302913	University Heart Center Freiburg - Bad Krozingen	Coronary Artery Disease\|Drug Resistance	December 2005	Not Applicable
NCT00433784	Hopital du Sacre-Coeur de Montreal	Coronary Artery Disease\|Elective Percutaneous Coronary Intervention	September 2004	Phase 4
NCT03661411	General Hospital of Shenyang Military Region	Stroke	October 17, 2018	Phase 4
NCT02285751	Medical University of Vienna	Critical Illness	November 2012	Phase 2
NCT00335452	Sanofi\|Bristol-Myers Squibb	Acute Coronary Disease\|Angina Unstable	June 2006	Phase 3
NCT01409616	Astellas Pharma Inc	Pharmacodynamic Interaction\|Healthy Subjects	April 2009	Phase 1
NCT04738097	Mazandaran University of Medical Sciences	Ischemic Stroke\|Transient Ischemic Attack	August 8, 2021	Phase 3
NCT01192724	Yonsei University	Coronary Artery Disease	March 2010	Phase 4
NCT00821834	Sanofi	Stable Angina\|Myocardial Infarction	December 2008	Phase 3
NCT02086903	Dong-A University	Pharmacodynamics	February 2014	Phase 3
NCT00363753	University of California, San Diego	Transient Ischemic Attack\|Stroke\|Aspirin\|Clopidogrel	August 2006	Phase 1
NCT02817789	University Hospital, Bordeaux	Aortic Valve Stenosis	May 9, 2016	Phase 3
NCT02944123	Dong-A University	Acute Coronary Syndrome	September 2016	Phase 3
NCT00889044	Sheba Medical Center	Platlet Aggregation\|Major Bleeding Outcomes	April 2009	Phase 3
NCT01905566	CHEOL WHAN LEE, M.D., Ph.D\|AstraZeneca\|CardioVascular Research Foundation, Korea\|Asan Medical Center	Plaque, Atherosclerotic	September 2013	Phase 4
NCT02054663	Ottawa Heart Institute Research Corporation	Acute Coronary Syndrome	December 2013	Phase 4
NCT00942175	Takeda	Healthy	December 2009	Phase 1
NCT04434365	Peking Union Medical College Hospital	Stable Coronary Artery Disease\|Percutaneous Coronary Intervention	June 21, 2019	Phase 1\|Phase 2
NCT01146301	R&D Cardiologie	Carotid Stenosis	March 2008	Phase 4
NCT01069302	Takeshi Morimoto\|Kyoto University, Graduate School of Medicine	Coronary Artery Disease	February 2010	Phase 4
NCT02048228	Chinese PLA General Hospital	CLOPIDOGREL, POOR METABOLISM of (Disorder)	October 2014	Phase 2\|Phase 3
NCT00977938	Baim Institute for Clinical Research\|Abbott\|Boston Scientific Corporation\|Bristol-Myers Squibb\|Sanofi-Synthelabo\|Cordis Corporation\|Eli Lilly and Company\|Daiichi Sankyo, Inc.\|Medtronic	Coronary Artery Disease	October 2009	Phase 4
NCT02869009	General Hospital of Shenyang Military Region	Ischemic Stroke	November 2016	Early Phase 1
NCT02696226	The Cleveland Clinic	Aortic Valve Disorder	February 2016	Not Applicable
NCT03947229	Yonsei University	Coronary Artery Disease\|DES	August 14, 2019	Phase 4
NCT04333407	Imperial College London	COVID-19	April 3, 2020	Not Applicable
NCT00222261	Ullevaal University Hospital\|The Norwegian Council for Cardiovascular Diseases.\|Ada and Hagbart Waages Humanitarian and Charity Foundation\|Alf and Aagot Helgesens Research Foundation.\|Oslo University Hospital	Coronary Heart Disease\|Angina Pectoris\|Atherosclerosis	April 2003	Phase 4
NCT04057300	McGill University Health Centre+Research Institute of the McGill University Health Centre\|Canadian Institutes of Health Research (CIHR)	Acute Coronary Syndrome	October 1, 2018	Phase 4
NCT04171687	HK inno.N Corporation	Healthy	October 21, 2019	Phase 1
NCT02663713	University of Patras\|AstraZeneca	Myocardial Infarction\|Diabetes Mellitus\|Renal Disease\|Coronary Artery Disease	January 2017	Phase 4
NCT00910299	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.	Coronary Artery Disease (CAD)	July 2009	Phase 2
NCT01621750	Dr. Reddy´s Laboratories Limited	Fasting	August 2008	Phase 1
NCT02983214	University of Ioannina\|LIBYTEC Pharmaceutical S.A.	Ischemic Stroke\|Peripheral Artery Disease\|Diabetes Mellitus, Type 2	November 2016	Phase 4
NCT02070159	Dong-A University	Coronary Artery Disease	December 2011	Phase 3
NCT00385944	Eli Lilly and Company\|Daiichi Sankyo, Inc.	Acute Coronary Syndrome	March 2007	Phase 2
NCT02394145	Kyunghee University Medical Center	Chronic Kidney Disease	September 2009	Phase 3
NCT03150680	AHEPA University Hospital\|LABNET IAE - Private Reference Diagnostic Laboratory	Coronary Artery Disease	September 1, 2017
NCT02675205	Fondation Ophtalmologique Adolphe de Rothschild	Cerebral Aneurysm	December 2015	Phase 3
NCT00528411	AstraZeneca	Coronary Artery Disease	October 2007	Phase 2
NCT03698513	Bristol-Myers Squibb	Healthy Volunteers	October 4, 2018	Phase 1
NCT02327624	Sheffield Teaching Hospitals NHS Foundation Trust\|AstraZeneca	Coronary Artery Disease	June 2015	Phase 4
NCT01505790	Assistance Publique Hopitaux De Marseille	Acute Coronary Syndromes	July 2011	Phase 3
NCT01447563	Hospital Universitario Dr. Jose E. Gonzalez	Comparative Bioavailability of Clopidogrel Tablets	May 2008	Phase 1
NCT02224131	Beijing Tiantan Hospital	Embolic Stroke	January 2015	Phase 4
NCT00734123	Hospital Arnau de Vilanova\|Pfizer	Atherosclerosis\|Cardiovascular Diseases	April 2008	Phase 4
NCT00858715	Medical University of Vienna	Atherosclerosis\|Angioplasty	May 2008	Not Applicable
NCT01706510	Rapid City Regional Hospital, Inc\|AstraZeneca	Coronary Artery Disease	December 2012	Phase 4
NCT02201667	RenJi Hospital	Acute Coronary Syndrome	August 2014	Phase 4
NCT00822666	Assistance Publique - Hôpitaux de Paris\|Institut National de la Santé Et de la Recherche Médicale, France	Coronary Artery Disease	October 2008	Phase 3
NCT01506713	Dr. Reddy´s Laboratories Limited	Fasting	September 2006	Phase 1
NCT02233790	First Hospital of China Medical University\|AstraZeneca	Myocardial Infarction\|No-Reflow Phenomenon	December 2014	Phase 4
NCT02548611	LMU Klinikum	Angina Pectoris	September 2015	Phase 4
NCT00228423	Ottawa Heart Institute Research Corporation\|Sanofi\|Bristol-Myers Squibb	Atherosclerosis	May 2006	Phase 2
NCT00152646	University Hospital, Angers	Peripheral Arterial Disease	March 2005	Phase 4
NCT00163267	University Hospital Tuebingen	Peripheral Vascular Diseases	September 2005	Phase 2\|Phase 3
NCT02567461	University of Florida\|Daiichi Sankyo, Inc.	Coronary Artery Disease	March 2016	Phase 4
NCT03814642	HK inno.N Corporation	Healthy	January 21, 2019	Phase 1
NCT02829151	Yonsei University	Critical Limb Ischemia	February 21, 2017	Phase 4
NCT03054207	Jules Desmeules\|University Hospital, Geneva	Hiv	June 2015	Phase 1
NCT01174693	Gangnam Severance Hospital\|Myung In Pharmaceutical Company\|Yonsei University	Cerebral Infarction	March 2010	Phase 4
NCT02742987	Campus Bio-Medico University	Coronary Artery Disease\|Diabetes Mellitus	March 2014	Phase 4
NCT01684813	Fundación Pública Andaluza para la gestión de la Investigación en Sevilla\|Andaluz Health Service	Diabetes Mellitus Type II\|Acute Coronary Syndrome	October 2012	Phase 4
NCT02211066	Hospital Clinic of Barcelona\|AstraZeneca	Patients Who Are Scheduled to Undergo a PCI (Percutaneous Coronary Intervention) for CTO (Chronic Total Occlusion)	October 2014	Phase 4
NCT00432120	Charles University, Czech Republic	Ischemic Heart Disease	March 2006	Phase 3
NCT00797056	Washington University School of Medicine	Peripheral Vascular Diseases	April 2008	Early Phase 1
NCT03385538	Zealand University Hospital	Ischemic Stroke	November 1, 2015	Phase 4
NCT02505399	University Hospital, Toulouse	Atherosclerosis	November 2015	Phase 4
NCT01283282	Emory University	Coronary Artery Disease	January 2008	Phase 4
NCT01598337	Prince Sultan Cardiac Center, Adult Cardiology Department.	Coronary Artery Disease	April 2011	Phase 3
NCT04368377	University of Milan\|Fondazione Un Cuore per Milano - a no profit foundation	Pneumonia, Viral\|Corona Virus Infection\|Respiratory Failure\|Embolism and Thrombosis	April 6, 2020	Phase 2
NCT01959451	LMU Klinikum	Acute Coronary Syndrome	September 2013	Phase 4
NCT02699008	Wuhan Asia Heart Hospital	Acute Coronary Syndrome	January 2014	Not Applicable
NCT00020189	National Cancer Institute (NCI)	Head and Neck Cancer\|Thromboembolism	June 2000	Phase 2
NCT00775762	Catholic University of the Sacred Heart	Polyvascular Disease\|Cardiovascular Disease	November 2008	Phase 3
NCT00648947	Mylan Pharmaceuticals Inc\|MylanPharma	Healthy	December 2004	Phase 1
NCT01979445	The Medicines Company	Coronary Artery Disease (CAD)	December 2, 2013	Phase 2
NCT01930591	Unity Health Toronto\|Prairie Vascular Research Inc.	Acute Myocardial Infarction	May 2014	Phase 3
NCT02224066	Hospital de Meixoeiro	Severe Aortic Valve Stenosis\|Transcatheter Aortic Valve Implantation\|Transcatheter Aortic Valve Replacement	January 2016	Phase 4
NCT01777503	Arcispedale Santa Maria Nuova-IRCCS\|ANMCO Italian Association of Hospital Cardiologist\|Italian Society of Invasive Cardiology	Acute Coronary Syndrome\|Coronary Arteriosclerosis\|Myocardial Ischemia\|Cardiovascular Diseases	November 2012	Phase 4
NCT01523366	AstraZeneca	Stable Coronary Artery Disease	April 2012	Phase 4
NCT02411903	The Third Affiliated Hospital of Guangzhou Medical University	Cerebral Infarction\|Clopidogrel,Poor Metabolism of (Disorder)	March 2015	Phase 4
NCT02433587	University Hospitals Cleveland Medical Center	Peripheral Arterial Disease\|Endovascular Procedures	October 2019	Phase 3
NCT00714961	Sanofi\|Bristol-Myers Squibb	Acute Coronary Syndromes	February 2003	Phase 3
NCT00816166	Codman & Shurtleff	Ischemic Stroke\|Transient Ischemic Attack	October 2008	Phase 2\|Phase 3
NCT02494284	CHEOL WHAN LEE, M.D., Ph.D\|CardioVascular Research Foundation, Korea\|Medtronic\|Chong Kun Dang Pharmaceutical Corp.\|Asan Medical Center	Coronary Artery Disease	December 22, 2015	Phase 4
NCT00391872	AstraZeneca	Acute Coronary Syndrome	October 2006	Phase 3
NCT01422109	Yuhan Corporation	Acute Coronary Syndrome	July 2011	Phase 1
NCT00343876	Intermountain Health Care, Inc.\|Bristol-Myers Squibb\|Sanofi-Synthelabo	Coronary Artery Disease	July 2005	Phase 4
NCT00693069	Hopital du Sacre-Coeur de Montreal	Coronary Artery Disease	September 2004	Phase 3
NCT01806090	Chinese University of Hong Kong	Gastrointestinal Bleeding	February 2012	Phase 4
NCT00684203	Merck Sharp & Dohme LLC	Atherosclerosis\|Myocardial Ischemia\|Myocardial Infarction	December 1, 2006	Phase 2
NCT00776633	Deutsches Herzzentrum Muenchen	Coronary Artery Disease\|Atrial Fibrillation	September 2008	Phase 4
NCT04409834	The TIMI Study Group	COVID-19\|Venous Thromboembolism\|Arterial Thrombosis	August 5, 2020	Phase 4
NCT01212302	Ruhr University of Bochum	Coronary Artery Disease	October 2008	Not Applicable
NCT03942458	Jiangsu vcare pharmaceutical technology co., LTD	Healthy Subjects\|PK+PD	April 3, 2019	Phase 1
NCT00105209	Kawut, Steven, MD\|National Heart, Lung, and Blood Institute (NHLBI)\|Columbia University	Hypertension, Pulmonary	April 2002	Phase 2
NCT00360386	Sanofi\|Bristol-Myers Squibb	Ischemia	March 2004	Phase 2
NCT01129414	Sanofi\|Bristol-Myers Squibb	Healthy	June 2009	Phase 1
NCT01950416	University of Patras	ST Elevation Myocardial Infarction\|Fibrinolysis\|P2Y12 Inhibitor	March 2013	Phase 4
NCT01482117	Inje University	Interaction	November 2011	Not Applicable
NCT01512485	Dr. Reddy´s Laboratories Limited	Healthy	October 2006	Phase 1
NCT03568890	Centre de Recherche de l´Institut Universitaire de Cardiologie et de Pneumologie de Quebec\|Institut universitaire de cardiologie et de pneumologie de Québec, University Laval	Left Atrial Appendage Closure\|Thrombosis\|Stroke\|TIA\|Bleeding	September 1, 2018	Phase 4
NCT00853450	AstraZeneca	Antiplatelet Effect	February 2009	Phase 1
NCT00396877	Sanofi\|Bristol-Myers Squibb	Heart Defects, Congenital	November 2006	Phase 3
NCT01768637	University of Texas Southwestern Medical Center\|American Heart Association	Chronic Kidney Disease	January 2013	Phase 1
NCT02222987	Boehringer Ingelheim	Healthy	February 1999	Phase 1
NCT03775746	East and North Hertfordshire NHS Trust\|University of Hertfordshire	Acute Coronary Syndrome	January 8, 2019	Phase 4
NCT02989558	University of Athens	Aortic Valve Stenosis	December 2016	Phase 3
NCT05210595	Dong-A University	Acute Myocardial Infarction\|Ticagrelor	January 1, 2022	Phase 4
NCT01335048	Ospedale Misericordia e Dolce	Stable Angina	April 2011	Phase 4
NCT00059306	University of British Columbia\|National Institute of Neurological Disorders and Stroke (NINDS)	Cerebrovascular Accident\|Hypertension	February 2003	Phase 3
NCT00243178	Sanofi\|Bristol-Myers Squibb	Atrial Fibrillation\|Vascular Risk	July 2003	Phase 3
NCT04219774	Duke University	Cognition Disorder\|Stroke\|Occlusion Carotid	January 4, 2019	Phase 2
NCT01995370	Japan Cardiovascular Research Foundation\|Otsuka Pharmaceutical Co., Ltd.	Noncardioembolic Cerebral Infarction	December 13, 2013	Phase 4
NCT01107899	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.	Acute Coronary Syndromes	October 2009	Phase 1
NCT02640794	Centre de Recherche de l´Institut Universitaire de Cardiologie et de Pneumologie de Quebec\|Institut universitaire de cardiologie et de pneumologie de Québec, University Laval	Aortic Valve Disease\|Myocardial Infarction\|Stroke\|Bleeding	January 2015	Phase 4
NCT01630642	Torrent Pharmaceuticals Limited	Healthy		Phase 1
NCT01123824	Sanofi\|Bristol-Myers Squibb	Healthy	April 2009	Phase 1
NCT05122741	University of Messina\|Natasha Irrera\|Gianluca Di Bella\|Antonio Micari\|Roberto Licordari	Myocardial Infarction\|Myocardial Fibrosis\|Myocardial Remodeling, Ventricular	December 1, 2021
NCT01210339	AstraZeneca	Healthy Volunteers	November 2010	Phase 1
NCT00648453	Sanofi\|Bristol-Myers Squibb	Peripheral Arterial Disease	December 2002	Phase 4
NCT01661322	University of Nottingham	Stroke	April 2009	Phase 3
NCT02439190	Bristol-Myers Squibb	Thrombosis	September 2015	Phase 1
NCT01264640	University of Rostock	Healthy Volunteers	July 2010	Not Applicable
NCT05546320	Chinese Academy of Medical Sciences, Fuwai Hospital	Patent Foramen Ovale\|Migraine	October 15, 2022	Phase 4
NCT01465828	Gennaro Sardella\|University of Roma La Sapienza	Acute Coronary Syndrome	October 2011	Phase 3
NCT02331511	Shahid Beheshti University of Medical Sciences	Complication of Cardiac Defibrillator\|Disorder of Cardiac Pacemaker System\|Venous Occlusion	October 2015	Not Applicable
NCT01961856	University of Patras	Platelet Reactivity	September 2013	Phase 3
NCT02938182	First Affiliated Hospital Xi´an Jiaotong University	Migraine	October 2016	Phase 4
NCT00640679	Deutsches Herzzentrum Muenchen	Coronary Artery Disease	April 2008	Phase 4
NCT02320357	University Hospital, Bordeaux\|Ministry for Health and Solidarity, France	Systemic Lupus Erythematous	August 19, 2015	Phase 1\|Phase 2
NCT01774838	University of Cologne	Acute Coronary Syndrome\|Unstable Angina	October 2014	Phase 3
NCT01603342	Novo Nordisk A+S	Haemostasis\|Healthy	December 2007	Phase 1
NCT01011257	Neil Kleiman, MD\|The Methodist Hospital Research Institute	Coronary Artery Disease	September 2009	Phase 4
NCT03759067	Korea University Anam Hospital	Angina, Stable	October 18, 2010	Not Applicable
NCT00781573	North Texas Veterans Healthcare System	Myocardial Infarction	September 11, 2008	Not Applicable
NCT03823274	Yuhan Corporation	Ischemic Stroke	April 1, 2019
NCT01896557	University of Sao Paulo General Hospital\|InCor Heart Institute	Coronary Artery Disease\|Drug Interaction Potentiation	October 2011	Phase 4
NCT02093299	Zealand University Hospital	Stroke	December 2012
NCT03088072	Scripps Health\|Daiichi Sankyo, Inc.	Non-Valvular Atrial Fibrillation\|Left Atrial Appendage Closure	March 23, 2017	Phase 4
NCT01121224	VA Office of Research and Development	Saphenous Vein Graft Atherosclerosis	January 11, 2012	Phase 4
NCT05047172	University of Florida\|National Institute of Neurological Disorders and Stroke (NINDS)\|University of Cincinnati\|Medical University of South Carolina\|Janssen Scientific Affairs, LLC\|AstraZeneca	Intracranial Arteriosclerosis\|Stroke	August 2, 2022	Phase 3
NCT00935506	Bristol-Myers Squibb	Cardiovascular Disease	July 2009	Phase 1
NCT05359224	Yonsei University\|Severance Hospital\|Gangnam Severance Hospital\|Bucheon St. Mary´s Hospital\|International St. Mary´s Hospital\|Ewha Woman´s University Seoul Hospital	Intracranial Aneurysm	June 13, 2022	Phase 4
NCT01758614	Xuanwu Hospital, Beijing	Carotid Artery Occlusion\|Middle Cerebral Artery Occlusion\|Stroke	June 6, 2013	Phase 3
NCT00109382	University of Calgary\|Canadian Institutes of Health Research (CIHR)\|Canadian Stroke Consortium (CSC)	Transient Ischemic Attack\|Stroke	May 2003	Phase 2\|Phase 3
NCT01106534	Abbott Medical Devices\|Baim Institute for Clinical Research\|Bristol-Myers Squibb\|Eli Lilly and Company\|Daiichi Sankyo, Inc.	Chronic Total Occlusion of Coronary Artery\|Vascular Disease\|Myocardial Ischemia\|Coronary Artery Stenosis\|Coronary Disease\|Coronary Artery Disease\|Coronary Restenosis	August 2009	Phase 4
NCT01014624	Daiichi Sankyo, Inc.	Coronary Artery Disease	February 2010	Phase 4
NCT00669149	Centre Hospitalier de PAU	Coronary Artery Disease	June 2008	Phase 4
NCT04661709	Guang´anmen Hospital of China Academy of Chinese Medical Sciences\|Special Project of National Traditional Chinese Medicine Clinical Research Base of State Administration of Traditional Chinese Medicine\|National Natural Science Foundation of China	Coronary Heart Disease\|Unstable Angina\|Chinese Herbal Medicine	March 1, 2021	Phase 4
NCT02224534	Gyeongsang National University Hospital\|Chinese PLA General Hospital\|Chungnam National University Hospital\|Pusan National University Yangsan Hospital\|National University Heart Centre, Singapore\|Ulsan University Hospital\|Kyungpook National University Hospital\|Samsung Changwon Hospital\|Kyunghee University Medical Center\|Chungbuk National University Hospital\|Chonnam National University Hospital\|Seoul National University Bundang Hospital	ST Elevation Myocardial Infarction	October 2014	Phase 4
NCT00724880	Catharina Ziekenhuis Eindhoven	Coronary Artery Disease	June 2006	Phase 4
NCT01159639	University of Zagreb	Coronary Artery Disease\|Aspirin Resistance	June 2010	Phase 4
NCT02966119	University Hospital, Lille\|Région Hauts de France, France\|Ministry of Health, France	Cerebral Hemorrhage	December 7, 2016	Phase 3
NCT02639143	First Affiliated Hospital of Harbin Medical University	Inflammation\|Thrombosis	December 2015	Phase 4
NCT02171598	Boehringer Ingelheim	Healthy	February 2009	Phase 1
NCT03599284	Jiangsu vcare pharmaceutical technology co., LTD	Coronary Artery Disease\|Percutaneous Coronary Intervention\|Platelet Aggregation Inhibitors	August 30, 2018	Phase 2
NCT01955642	Centre Hospitalier Universitaire de Saint Etienne\|Groupe de Recherche sur la Thrombose	Brain Ischemia\|Ischemic Attack	September 2013
NCT04431349	Ajou University School of Medicine	Blood Loss, Surgical\|Ticagrelor\|Clopidogrel	January 1, 2016
NCT04937699	Second Affiliated Hospital, School of Medicine, Zhejiang University	Acute Coronary Syndrome\|Percutaneous Coronary Intervention	January 2023	Phase 4
NCT01156571	The Medicines Company	Atherosclerosis\|Percutaneous Coronary Intervention\|Acute Coronary Syndrome	September 2010	Phase 3
NCT04850417	Spanish Society of Cardiology\|Instituto de Investigación Sanitaria Hospital Universitario de la Princesa\|Fundación de Investigación Biomédica - Hospital Universitario de La Princesa	Spontaneous Coronary Artery Dissection	April 30, 2021	Phase 4
NCT04805710	Shenyang Northern Hospital	Rivaroxaban	March 17, 2021	Phase 4
NCT00698607	Seoul National University Hospital\|Abbott\|Boston Scientific Corporation	Coronary Artery Disease	June 2008	Phase 4
NCT01700322	Johannes Gutenberg University Mainz	Coronary Artery Disease	August 2012	Phase 4
NCT00830960	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.	Acute Coronary Syndrome	February 2009	Phase 3
NCT04824911	Chang Gung Memorial Hospital	Acute Stroke\|Dual Antiplatelet Therapy\|Statin	March 23, 2021	Phase 2
NCT01830491	Hanmi Pharmaceutical Company Limited	Coronary Artery Disease (CAD)	March 2009	Phase 4
NCT01955200	The First Affiliated Hospital with Nanjing Medical University\|National Natural Science Foundation of China	Coronary Artery Disease	October 5, 2013	Phase 4
NCT02959606	Seoul National University Hospital	Peripheral Arterial Disease	December 2016	Phase 4
NCT00778193	Research Associates of New York, LLP	Gastroduodenal Ulcer	October 2007	Phase 4
NCT00728156	Newcastle-upon-Tyne Hospitals NHS Trust\|British Heart Foundation\|University of Newcastle Upon-Tyne	Type 2 Diabetes Mellitus\|Coronary Artery Disease	August 2009	Phase 4
NCT02514642	First Affiliated Hospital of Harbin Medical University	Coronary Artery Disease	July 2015	Phase 4
NCT04001894	First Affiliated Hospital of Harbin Medical University	Platelet Reactivity	July 2, 2019	Phase 4
NCT04165629	Clinical Centre of Serbia	Peripheral Artery Disease\|Critical Limb Ischemia\|Claudication, Intermittent	January 1, 2020
NCT00330772	Hamilton Health Sciences Corporation\|Bristol-Myers Squibb\|McMaster University	Coronary Artery Disease\|Coronary Artery Bypass Grafting	July 2006	Phase 3
NCT05553613	Kafrelsheikh University	Ischemic Stroke	October 17, 2022	Phase 3
NCT05098704	University Hospital, Bordeaux\|Ministry for Health and Solidarity, France	Scleroderma\|Systemic Sclerosis	June 22, 2022	Phase 2\|Phase 3
NCT03430661	Idorsia Pharmaceuticals Ltd.	Healthy	January 24, 2018	Phase 1
NCT03072121	Jun Li\|Shanghai Hutchison Pharmaceuticals Limited\|Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Coronary Artery Disease(CAD)	June 2017	Phase 4
NCT02831218	Seung-Jung Park\|CardioVascular Research Foundation, Korea\|Asan Medical Center	Percutaneous Transluminal Coronary Angioplasty	December 2016	Not Applicable
NCT01263093	Eli Lilly and Company	Major Depressive Disorder	December 2010	Phase 1
NCT05573958	Sarmad Zahoor\|University of Managemant and Technology, Pakistan\|Mayo Hospital Lahore\|Punjab Institute of Cardology	Acute Coronary Syndrome	October 1, 2022	Phase 4
NCT01894789	Ottawa Heart Institute Research Corporation	Coronary Artery Disease	March 2013	Phase 2\|Phase 3
NCT01627431	University of Roma La Sapienza\|University of Florence	Peripheral Arterial Disease	July 2012	Phase 4
NCT01023360	National Taiwan University Hospital\|Haemonetics Corporation	30 Healthy People	May 2008	Phase 4
NCT01790997	Dexa Medica Group	Acute Ischemic Stroke	May 2012	Phase 3
NCT02925923	University of Alabama at Birmingham	Acute Coronary Syndrome\|Angina, Unstable	November 1, 2016	Phase 2
NCT04946734	Guangdong Provincial People´s Hospital	PFO - Patent Foramen Ovale\|Migraine	July 15, 2021	Phase 3
NCT02379676	Kiyuk Chang\|AstraZeneca\|Seoul St. Mary´s Hospital	Endothelial Dysfunction\|Vascular Inflammation	January 2015	Phase 4
NCT02044250	Seoul National University Hospital\|Chong Kun Dang Pharmaceutical\|Samjin Pharmaceutical Co., Ltd.\|Daewoong Pharmaceutical Co. LTD.\|Hanmi Pharmaceutical co., ltd.	Coronary Heart Disease	February 2014	Phase 4
NCT02578706	Icahn School of Medicine at Mount Sinai\|National Heart, Lung, and Blood Institute (NHLBI)	HIV-1 Infection	October 2015	Phase 2
NCT01129063	Sanofi\|Bristol-Myers Squibb	Healthy	March 2009	Phase 1
NCT01115738	Eli Lilly and Company	Acute Coronary Syndrome	May 2010	Phase 2
NCT02044146	Ottawa Heart Institute Research Corporation\|Canadian Institutes of Health Research (CIHR)	Acute Coronary Syndrome\|Percutaneous Coronary Intervention	September 2014	Phase 2\|Phase 3
NCT02939872	Seung-Jung Park\|CardioVascular Research Foundation, Korea\|Asan Medical Center	Percutaneous Transluminal Coronary Angioplasty\|Coronary Disease	March 9, 2017	Phase 4
NCT01371058	Shenyang Northern Hospital	Coronary Artery Disease	March 2011	Phase 4
NCT02247128	St. Antonius Hospital	Aortic Valve Disease\|Myocardial Infarction\|Stroke\|Bleeding	January 2014	Phase 4
NCT03078465	Nanjing First Hospital, Nanjing Medical University	Coronary Artery Disease	June 20, 2017	Phase 3
NCT01147588	AstraZeneca	Healthy	May 2010	Phase 1
NCT01815008	Johns Hopkins University	Platelet Aggregation\|Platelet Transcriptome\|Coronary Artery Disease	October 2012	Phase 4
NCT01463150	University of Patras	Platelet Reactivity	October 2011	Phase 4
NCT01612884	Indiana University	Thrombosis\|Coronary Artery Disease	August 2011	Phase 4
NCT00174759	Sanofi\|Bristol-Myers Squibb	Arterial Occlusive Diseases	September 2004	Phase 3
NCT01381185	University Hospital Ostrava	Acute Myocardial Infarction	May 2011	Phase 4
NCT04250116	Yonsei University	Atrial Fibrillation	April 28, 2020	Phase 4
NCT01094457	Shenyang Northern Hospital	Acute Coronary Syndromes\|Percutaneous Coronary Intervention\|Clopidogrel Low Responsiveness	March 2009	Phase 4
NCT04091074	Assiut University	Carotid Stenosis	January 1, 2022	Phase 1
NCT01012193	Gyeongsang National University Hospital	Coronary Artery Disease\|Percutaneous Coronary Intervention	January 2008	Phase 4
NCT00357968	Eli Lilly and Company\|Daiichi Sankyo, Inc.\|The TIMI Study Group	Coronary Artery Disease	August 2006	Phase 2
NCT02707445	Korea University Anam Hospital	Myocardial Ischemia\|CLOPIDOGREL, POOR METABOLISM of (Disorder)	September 2011	Not Applicable
NCT03039205	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Platelet Aggregation\|Adenosine\|Coronary Artery Disease\|Kidney Dysfunction\|Antiplatelet Therapy	November 7, 2017	Phase 2
NCT03667066	The University of The West Indies	Platelet Dysfunction	September 1, 2017
NCT03197298	Thorax Centrum Twente	Acute Coronary Syndrome\|Percutaneous Coronary Intervention\|Drug-Eluting Stents	December 21, 2012
NCT02060786	Ajou University School of Medicine\|Dong-A Pharmaceutical	Acute Coronary Syndrome	October 2010	Phase 4
NCT05166538	Yonsei University	Multi Vessel Coronary Artery Disease	February 1, 2022	Phase 4
NCT02554721	Otsuka Pharmaceutical Co., Ltd.	Healthy	August 2015	Phase 1
NCT03496506	Actelion	Healthy Subjects	March 5, 2018	Phase 1
NCT03062462	First Affiliated Hospital of Harbin Medical University	Coronary Artery Disease\|Clopidogrel, Poor Metabolism of	February 10, 2017	Phase 2\|Phase 3
NCT00814268	Sanofi\|Bristol-Myers Squibb	Stroke	December 2008	Phase 4
NCT04116931	The First Affiliated Hospital with Nanjing Medical University	Acute Coronary Syndrome (ACS)	June 22, 2020	Phase 4
NCT00130039	Asan Medical Center\|Korea Otsuka International Asia Arab	Cerebral Infarction\|Atherosclerosis	August 2005	Phase 4
NCT02123004	Jinan Central Hospital	ST-Segment Elevation Myocardial Infarction	April 2014	Phase 4
NCT00839345	Charles University, Czech Republic	Coronary Artery Disease
NCT02108808	University of Patras	Fractional Flow Reserve	April 2014	Phase 4
NCT01012219	Merck Sharp & Dohme LLC	Primary Hypercholesterolemia\|Mixed Hyperlipidemia	November 2009	Phase 1
NCT01864005	AstraZeneca	Non-ST or ST Elevation Acute Coronary Syndromes	May 2013	Phase 4
NCT03190005	Taipei City Hospital	Stable Angina	January 1, 2017
NCT01738100	Hyeon-Cheol Gwon\|Samsung Medical Center	ST-Segment Elevation Myocardial Infarction	September 2012	Phase 2
NCT01846559	Sheffield Teaching Hospitals NHS Foundation Trust\|University of Sheffield	Healthy	April 2013	Phase 4
NCT05162053	Jiangsu vcare pharmaceutical technology co., LTD	Acute Coronary Syndrome	December 9, 2021	Phase 1
NCT03078257	The First Affiliated Hospital with Nanjing Medical University\|National Natural Science Foundation of China	Coronary Artery Disease	January 1, 2016	Phase 1
NCT02298088	Hospital do Coracao	Acute ST Segment Elevation Myocardial Infarction\|Thrombolysis in Myocardial Infarction Flow	August 2015	Phase 3
NCT01235351	The TIMI Study Group\|Bristol-Myers Squibb\|Sanofi	Myocardial Infarction\|Percutaneous Coronary Intervention	October 2010	Phase 2
NCT01260584	Daiichi Sankyo, Inc.	Coronary Artery Disease	November 2010	Phase 4
NCT03766581	Bristol-Myers Squibb\|Janssen, LP	Acute Ischemic Stroke\|Transient Ischemic Attack (TIA)	January 27, 2019	Phase 2
NCT05257824	Seoul National University Bundang Hospital\|Soonchunhyang University Hospital\|Soonchunhyang University Cheonan Hospital\|Seoul National University Hospital\|Pusan National University Yangsan Hospital\|Keimyung University Dongsan Medical Center\|Seoul St. Mary´s Hospital\|Uijeongbu St. Mary´s Hospital\|Ajou University School of Medicine\|Chungnam National University Sejong Hospital\|Severance Hospital\|Asan Medical Center\|Yonsei University Gangnam Severance Hospital	Aneurysm Cerebral\|Endovascular Procedures	June 23, 2022	Phase 4
NCT03614832	First Affiliated Hospital of Harbin Medical University	Platelet Reactivity	May 1, 2018	Phase 4
NCT04006288	University of Florida\|Janssen, LP	Coronary Artery Disease	September 6, 2019	Phase 4
NCT01097343	University of North Carolina, Chapel Hill	Disease Susceptibility	March 2010	Phase 2
NCT02446730	Chonnam National University Hospital	Cardiac Death\|Hemorrhage\|Cerebrovascular Accident\|Myocardial Infarction	September 2014	Phase 4
NCT02486367	University Hospitals Cleveland Medical Center	Aortic Stenosis\|Inflammation\|Thrombosis	June 2015	Phase 4
NCT02628587	Hospital Central San Luis Potosi, Mexico	Acute Coronary Syndrome	February 2016	Phase 4
NCT03119012	Samsung Medical Center	Coronary Artery Disease\|Stents\|Atherosclerosis	April 19, 2017	Phase 4
NCT01129375	Sanofi\|Bristol-Myers Squibb	Healthy	February 2009	Phase 1
NCT00262275	Papworth Hospital NHS Foundation Trust	Ischemic Heart Disease	July 2002	Not Applicable
NCT02026219	Inha University Hospital	Non-ST Segment Elevation Myocardial Infarction\|ST Segment Elevation Myocardial Infarction	October 2013	Phase 4
NCT04654052	Fundación EPIC	Acute Coronary Syndrome\|Acute Myocardial Infarction\|Coronary Artery Disease\|Percutaneous Coronary Intervention	July 2, 2021	Phase 4
NCT02587260	Erasmus Medical Center\|Covance	Cardiovascular Diseases	December 17, 2015	Phase 4
NCT00305162	The Medicines Company	Myocardial Infarction (MI)\|Acute Coronary Syndromes (ACS)	April 2006	Phase 3
NCT01495845	University of North Carolina, Chapel Hill\|Kerr Drug\|Laboratory Corporation of America	Stroke\|Transient Ischemic Attack\|Myocardial Infarction	December 2011	Phase 1
NCT00882388	Seoul National University Hospital	Healthy	March 2005	Phase 4
NCT01394848	Yonsei University\|OrbusNeich\|Yuhan Corporation	Stable Angina	October 2011	Phase 4
NCT04619381	Vanderbilt University Medical Center	Coronary Artery Disease	March 19, 2021
NCT02319941	Seung-Jung Park\|AstraZeneca\|Roche Pharma AG\|KBM pharm\|Asan Medical Center	Acute Coronary Syndrome	May 20, 2015	Phase 2
NCT02163954	Kyunghee University Medical Center\|Kyunghee University	Chronic Kidney Disease	January 2013	Phase 3
NCT01107912	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.	Coronary Artery Disease	March 2010	Phase 1
NCT00976092	Deutsches Herzzentrum Muenchen	Myocardial Infarction	September 2009	Phase 4
NCT03329261	Laboratoires Teriak	Diabetes Mellitus, Type 2\|NSTEMI - Non-ST Segment Elevation MI\|Coronary Angioplasty	December 7, 2017	Phase 4
NCT05233124	Instituto Nacional de Cardiologia Ignacio Chavez	Acute Coronary Syndrome\|Coronary Artery Ectasia	September 1, 2021	Phase 2
NCT02140801	Nanjing First Hospital, Nanjing Medical University	Thrombosis	May 1, 2014	Phase 4
NCT02556203	Bayer\|Janssen Research & Development, LLC	Transcatheter Aortic Valve Replacement	December 16, 2015	Phase 3
NCT01621451	Asan Medical Center\|Takeda	Early Gastric Cancer\|Gastric Dysplasia	June 2012	Phase 4
NCT00386191	Sanofi	Cerebral Infarction	September 2006	Phase 4
NCT02548650	University of Florida\|Merck Sharp & Dohme LLC	Myocardial Infarction\|Diabetes Mellitus\|Peripheral Arterial Disease	March 25, 2016	Phase 4
NCT01635426	Ain Shams University	Recurrent Pregnancy Loss	March 2012	Phase 2\|Phase 3
NCT04088513	First Affiliated Hospital, Sun Yat-Sen University	G6PD Deficiency\|Stroke	January 22, 2020	Phase 4
NCT02419820	IlDong Pharmaceutical Co Ltd\|Asan Medical Center	Acute Coronary Syndrome	March 2015	Phase 1
NCT03613857	Cairo University	Myocardial Infarction	April 15, 2017
NCT00979589	Beijing Tiantan Hospital\|University of California, San Francisco	Stroke\|Transient Ischemic Attack	December 2009	Phase 3
NCT05516784	Universiti Sains Malaysia	Coronary Artery Disease (CAD)	September 1, 2019	Phase 4
NCT00696566	Sheffield Teaching Hospitals NHS Foundation Trust\|British Heart Foundation\|University of Sheffield	Coronary Artery Disease	November 2007	Phase 1
NCT00619073	University of Massachusetts, Worcester\|Sanofi\|Bristol-Myers Squibb	Blood Platelets\|Clopidogrel	April 2008	Not Applicable
NCT00494156	C. Clay Cothren, MD\|Denver Health and Hospital Authority	Carotid Artery Injury\|Vertebral Artery Injury	July 2003	Not Applicable
NCT00418860	Samsung Medical Center\|Medtronic	Coronary Artery Disease	September 2006	Not Applicable
NCT00944333	Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS	Angina Pectoris\|Silent Ischemia	July 2009	Phase 3
NCT02121288	AstraZeneca	Peripheral Artery Disease\|Vascular Disease\|Arterial Occlusion Disease\|Intermittent Claudication\|Ankle Brachial Index (0.9 or Less)	December 2014	Phase 4
NCT02164864	Boehringer Ingelheim	Atrial Fibrillation\|Percutaneous Coronary Intervention	July 22, 2014	Phase 3
NCT04369534	University of Zagreb\|Croatian Science Foundation\|Clinical Hospital Centre Zagreb	Acute Coronary Syndrome\|STEMI\|NSTEMI - Non-ST Segment Elevation MI\|PLATELET AGGREGATION\|INDIVIDUALIZED THERAPY	December 1, 2015	Phase 4
NCT00915733	Gyeongsang National University Hospital	Myocardial Infarction	May 2009	Phase 4
NCT01572623	Campus Bio-Medico University	Carotid Stenosis	July 2011	Phase 4
NCT02094963	Seung-Jung Park\|CardioVascular Research Foundation, Korea\|Asan Medical Center	Acute Coronary Syndrome\|Myocardial Ischemia\|Heart Diseases\|Cardiovascular Diseases\|Angina Pectoris	July 5, 2014	Phase 4
NCT00749710	Tel-Aviv Sourasky Medical Center	Femoral Neck Fractures\|Pertrochanteric Fractures\|Antiaggregant Therapy	September 2008	Not Applicable
NCT02034292	IlDong Pharmaceutical Co Ltd\|Asan Medical Center	Acute Coronary Syndrome	February 2014	Phase 1
NCT01107925	Eli Lilly and Company\|Daiichi Sankyo Co., Ltd.	Coronary Artery Disease	March 2010	Phase 1
NCT01561950	Novo Nordisk A+S	Haemostasis\|Healthy	May 2008	Phase 1
NCT01341964	Population Health Research Institute	Drug Action Increased	May 2011	Phase 4
NCT01341600	University of Maryland, Baltimore\|Food and Drug Administration (FDA)\|National Cancer Institute (NCI)\|National Institute of General Medical Sciences (NIGMS)\|National Heart, Lung, and Blood Institute (NHLBI)	Metabolism of Clopidogrel	July 2010	Not Applicable
NCT02833948	ECRI bv\|Rigshospitalet, Denmark\|Bayer\|Cardialysis BV	Aortic Valve Stenosis\|Cardiovascular Diseases\|Heart Valve Diseases\|Ventricular Outflow Obstruction\|Thrombosis	May 2016	Phase 3
NCT00882739	Ospedale San Donato	Acute Myocardial Infarction	April 2009	Phase 4
NCT04142151	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	Ischemic Stroke\|Antiplatelet Effect	September 1, 2019	Not Applicable
NCT03961334	University of Zurich\|Swiss National Science Foundation	Stroke, Ischemic	December 5, 2019	Phase 3
NCT03330223	The First Affiliated Hospital with Nanjing Medical University	Renal Failure\|Coronary Artery Disease\|Hemolysis	November 10, 2017
NCT02565693	UMC Utrecht\|Dutch Heart Foundation\|ZonMw: The Netherlands Organisation for Health Research and Development	Cerebral Hemorrhage\|Atrial Fibrillation	September 2014	Phase 2
NCT01155765	University of Patras	Hemodialysis\|Chronic Renal Failure	May 2010	Phase 3
NCT00235950	AstraZeneca	Coronary Heart Disease	January 2004	Phase 4
NCT01109784	University of Patras	Coronary Artery Disease (CAD)\|Acute Coronary Syndrome (ACS)	April 2010	Phase 3
NCT02447809	The First Affiliated Hospital with Nanjing Medical University\|National Natural Science Foundation of China	Coronary Artery Disease	January 2015	Phase 4
NCT04502017	Texas Cardiac Arrhythmia Research Foundation	Device-Related Thrombosis\|Atrial Fibrillation\|Left Atrial Appendage Occlusion	August 5, 2020	Phase 4
NCT03006835	Xijing Hospital\|Shenzhen Salubris Pharmaceuticals Co., Ltd.	Coronary Heart Disease	January 2017	Phase 4
NCT00121446	University of Alberta\|Hoffmann-La Roche\|Sanofi\|Eli Lilly and Company	Myocardial Infarction	July 2003	Phase 2\|Phase 3
NCT01129427	Sanofi\|Bristol-Myers Squibb	Healthy	August 2009	Phase 1
NCT01743014	AHEPA University Hospital\|Aristotle University Of Thessaloniki	Diabetes Type 2\|Diabetic Nephropathy\|Vascular Disease	July 2012	Phase 4
NCT00817999	Creighton University	Healthy	November 2008	Phase 4
NCT02287909	University of Florida	Coronary Artery Disease	December 2014	Phase 4
NCT00059215	Eli Lilly and Company	Cardiovascular Diseases\|Heart Diseases	April 2003	Phase 2
NCT00513149	National Taiwan University Hospital	Coronary Artery Disease	July 2006	Phase 4
NCT01643031	Rabin Medical Center\|Tel Aviv Medical Center\|Sheba Medical Center\|Meir Medical Center\|Rambam Health Care Campus	Diabetes Mellitus\|Coronary Disease	August 2012	Phase 4
NCT02922465	Kowa Research Institute, Inc.	Healthy	September 2016	Phase 1
NCT03378934	Peking Union Medical College Hospital	Coronary Artery Disease\|Percutaneous Coronary Intervention	September 26, 2018	Phase 4
NCT00644657	University of Oklahoma	Coronary Artery Disease\|Chest Pain	March 2007	Not Applicable
NCT01102439	Population Health Research Institute	Coronary Artery Disease	April 2010	Phase 4
NCT00645918	Accumetrics, Inc.	Coronary Arteriosclerosis\|Acute Coronary Syndrome	June 2008	Not Applicable
NCT00356135	Eli Lilly and Company\|Daiichi Sankyo, Inc.	Coronary Arteriosclerosis\|Acute Coronary Syndrome	July 2006	Phase 2
NCT02559414	NYU Langone Health	HIV\|Cardiovascular Diseases\|Inflammation	February 2015	Phase 2
NCT00862420	Sanofi	Peripheral Arterial Disease (PAD)	February 2009	Phase 3
NCT02866175	Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company\|Daiichi Sankyo, Inc.	Atrial Fibrillation	February 24, 2017	Phase 3
NCT00372216	Stiftung Institut fuer Herzinfarktforschung\|Bristol-Myers Squibb\|Sanofi	Myocardial Infarction	October 2006	Phase 3
NCT01609647	Dong-A University	Acute Coronary Syndrome	September 2012	Phase 3
NCT01094275	Neil Kleiman, MD\|The Methodist Hospital Research Institute	Coronary Artery Disease	January 2010
NCT03150667	North Texas Veterans Healthcare System	Chronic Kidney Diseases\|Acute Coronary Syndrome	April 10, 2017	Phase 4
NCT03072082	Jun Li\|China Academy of Chinese Medical Sciences\|Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Coronary Artery Disease(CAD)	June 2017	Phase 4
NCT02032290	Azienda Policlinico Umberto I	Acute Coronary Syndrome:\|Non ST Elevation Myocardial Infarction\|ST Elevation Myocardial Infarction\|Unstable Angina	February 2014	Phase 4
NCT01630915	Torrent Pharmaceuticals Limited	Healthy		Phase 1
NCT01636180	Fundacja O?rodek Bada? Medycznych\|KCRI	Acute Myocardial Infarction	March 2012	Phase 4
NCT00954707	Cordis Corporation	Coronary Artery Disease	August 2009	Phase 4
NCT03774394	University of Florida\|Scott R. MacKenzie Foundation	Chronic Kidney Disease (CKD)\|Type 2 Diabetes Mellitus (T2DM)\|Coronary Artery Disease (CAD)	August 22, 2019	Phase 4
NCT00325390	Sanofi\|Daiichi Pharmaceuticals	Platelet Aggregation Inhibitors\|NSTEACS	July 2004	Phase 3
NCT02010632	Khon Kaen University	Pharmacodynamics	August 2013	Phase 1
NCT02384070	Odessa Heart Institute	Coronary Artery Disease	January 2009	Not Applicable
NCT00611286	Marco Valgimigli\|Università degli Studi di Ferrara	Coronary Artery Disease	December 2006	Phase 4
NCT02889549	First Affiliated Hospital of Harbin Medical University	Coronary Artery Disease	August 2016	Phase 2\|Phase 3
NCT00050817	Sanofi	Arteriosclerosis	October 2002	Phase 3
NCT01141153	Hospital Universitari Vall d´Hebron Research Institute	Atrial Fibrillation\|Stroke	June 2010	Phase 4
NCT02931045	Medical University of Warsaw\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Myocardial Infarction	December 30, 2017	Phase 4
NCT02519608	University Hospital of Ferrara	Coronary Artery Disease\|Chronic Obstructive Pulmonary Disease	September 2015	Phase 2
NCT01603082	AstraZeneca	Acute Coronary Syndrome	July 2012	Phase 4
NCT01802775	Daiichi Sankyo, Inc.\|UMC Utrecht	Peripheral Arterial Disease	February 6, 2013	Phase 2
NCT02330640	Chinese Academy of Medical Sciences, Fuwai Hospital	Antiplatelet Therapy of Coronary Artery Bypass	January 2016	Phase 4
NCT01572129	Campus Bio-Medico University	Acute Coronary Syndrome\|Myocardial Infarction	November 2011	Phase 4
NCT01742117	Mayo Clinic\|Spartan Bioscience Inc.\|Applied Health Research Centre\|National Heart, Lung, and Blood Institute (NHLBI)	Coronary Artery Disease\|Acute Coronary Syndrome\|Stenosis	May 2013	Phase 4
NCT01812330	General Hospital of Chinese Armed Police Forces	Acute Coronary Syndrome	January 2013	Phase 3
NCT01960296	Icahn School of Medicine at Mount Sinai\|Doris Duke Charitable Foundation	Clopidogrel	January 2012	Phase 2
NCT02309970	Rabin Medical Center	Ischemic Stroke	December 2014

Appearance

Oil

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 155.37 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1073 mL	15.5366 mL	31.0733 mL
5 mM	0.6215 mL	3.1073 mL	6.2147 mL
10 mM	0.3107 mL	1.5537 mL	3.1073 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.77 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.77 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: 2.5 mg/mL (7.77 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.

References

[1] Zongyu Zheng, et al. Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis. Int J Biol Sci. 2019 Jan.
[2] An insight into the interaction between clopidogrel and proton pump inhibitors By Shah, Bhavik S.; Parmar, Sanjay A.; Mahajan, Shailaja; Mehta, Anita A. From Current Drug Metabolism (2012), 13(2),225-235.

Synonyms

Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-

Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-

Clopidogrel

(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate

(S)-Methyl α-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-α-(o-chlorophenyl)acetate

SR 25990

(S)-Clopidogrel

(+)-(S)-Clopidogrel

Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate

R 130964

Thrombo

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