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[CAS NO. 117977-21-6] Rabeprazole Sulfide
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W003467 |
| Brand: | MCE |
| CAS: | 117977-21-6 |
Overview
| MDL | MFCD08063845 |
|---|---|
| Molecular Weight | 343.44 |
| Molecular Formula | C18H21N3O2S |
| SMILES | CC1=C(OCCCOC)C=CN=C1CSC2=NC3=CC=CC=C3N2 |
Summary
Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H + /K + )-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori . Rabeprazole has the potential for various peptic diseases treatment [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 291.17 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9117 mL | 14.5586 mL | 29.1172 mL |
| 5 mM | 0.5823 mL | 2.9117 mL | 5.8234 mL |
| 10 mM | 0.2912 mL | 1.4559 mL | 2.9117 mL |
References
- [1] Uno T, et al. Determination of rabeprazole and its active metabolite, rabeprazole thioether in human plasma by column-switching high-performance liquid chromatography and its application to pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life
- [2] Tsutsui N, et al. A novel action of the proton pump inhibitor rabeprazole and its thioether derivative against the motility of Helicobacter pylori. Antimicrob Agents Chemother. 2000 Nov;44(11):3069-73.
Synonyms
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