[CAS NO. 1185-57-5] Ammonium iron(III) citrate

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PRODUCTS SPECIFICATIONS [1185-57-5]

Catalog

HY-B1645

Brand

MCE

CAS

1185-57-5

DESCRIPTION [1185-57-5]

Overview

MDL	-
Molecular Weight	-
Molecular Formula	C6H8O7.xFe.xH3N
SMILES	OC(CC(C(O)=O)(O)CC(O)=O)=O.[x Fe(III)].[x NH3]

For research use only. We do not sell to patients.

4 Publications Citing Use of MCE

Summary

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to cause ferroptosis ^[1] . Ammonium iron(III) citrate can enhance protein production ^[2] .

In Vitro

Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter ^[1] .
Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas for Chlorella vulgaris FSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT05572892	University Hospital, Caen	Stroke	October 7, 2022

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H ₂ O : 33.33 mg/mL (Need ultrasonic)

DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)

In Vivo:

1.

Add each solvent one by one: PBS

Solubility: 50 mg/mL (Infinity mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.

References

Synonyms

1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium iron(3+) salt (1:?:?)

Citric acid, ammonium iron(3+) salt

1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium iron(3+) salt

Ferric ammonium citrate

Ammonium iron(III) citrate

Ammonium ferric citrate

FAC

Iron(III) ammonium citrate

E 381

FerriSeltz powder