[CAS NO. 1191-41-9] Ethyl linolenate

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PRODUCTS SPECIFICATIONS [1191-41-9]

Catalog

HY-N2073

Brand

MCE

CAS

1191-41-9

DESCRIPTION [1191-41-9]

Overview

MDL	MFCD07371452
Molecular Weight	306.48
Molecular Formula	C20H34O2
SMILES	CC/C=C\C/C=C\C/C=C\CCCCCCCC(OCC)=O

For research use only. We do not sell to patients.

Summary

Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC ₅₀ of 70 μM. Anti-melanogenesis Effects ^[1] .

In Vitro

Ethyl linolenate significantly blocks Forskolin-induced melanogenesis and inhibits tyrosinase activity ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Liquid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 326.29 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2629 mL	16.3143 mL	32.6286 mL
5 mM	0.6526 mL	3.2629 mL	6.5257 mL
10 mM	0.3263 mL	1.6314 mL	3.2629 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (8.16 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (8.16 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (8.16 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Sungran Huh, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull. 2010;33(7):1242-5.

Synonyms

9,12,15-Octadecatrienoic acid, ethyl ester, (9Z,12Z,15Z)-

Linolenic acid, ethyl ester

9,12,15-Octadecatrienoic acid, ethyl ester, (Z,Z,Z)-

Ethyl linolenate

Ethyl cis,cis,cis-9,12,15-octadecatrienoate

Ethyl α-linolenate

Ethyl (Z,Z,Z)-9,12,15-octadecatrienoate

Ethyl linolenoate

(Z,Z,Z)-9,12,15-Octadecatrienoic acid ethyl ester