[CAS NO. 1197033-19-4] 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

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PRODUCTS SPECIFICATIONS [1197033-19-4]

Catalog

HY-148503

Brand

MCE

CAS

1197033-19-4

DESCRIPTION [1197033-19-4]

Overview

MDL	-
Molecular Weight	899.97
Molecular Formula	C49H54N7O8P
SMILES	COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@]45[C@H]([C@](O[C@H]5C)([H])[C@H](N6C7=NC=NC(NC(C8=CC=CC=C8)=O)=C7N=C6)O4)OP(OCCC#N)N(C(C)C)C(C)C

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Summary

5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion ^[1] .

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References

[1] Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81.