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[CAS NO. 1198786-98-9] INT-777 (R-enantiomer)
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-15677A |
| Brand: | MCE |
| CAS: | 1198786-98-9 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 450.65 |
| Molecular Formula | C27H46O5 |
| SMILES | O[C@@H]1CC[C@@]2(C)[C@@]([C@@H](CC)[C@@H](O)[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@@H]4[C@H](C)C[C@@H](C)C(O)=O)([H])C1 |
Summary
INT-777 (R-enantiomer) is the R-enantiomer of INT-777, with EC 50 of 4.79 μM for TGR5, and less potent than INT-777.
In Vivo
INT-777 (R-enantiomer) is more choleretic than CA (4), but less than INT-777 [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 221.90 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.2190 mL | 11.0951 mL | 22.1902 mL |
| 5 mM | 0.4438 mL | 2.2190 mL | 4.4380 mL |
| 10 mM | 0.2219 mL | 1.1095 mL | 2.2190 mL |
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